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1. Full Text Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
by Fisher, Sheila A and Regueiro, Miguel D and Anderson, Carl A and Prescott, Natalie J and Mathew, Christopher G and Rutgeerts, Paul and Parkes, Miles and Steinhart, A Hillary and Drummond, Hazel and Bitton, Alain and Georges, Michel and Gut, Ivo and Jewell, Derek and Barrett, Jeffrey C and Daly, Mark J and Dewit, Olivier and Bumpstead, Suzannah and Hansoul, Sarah and Hugot, Jean-Pierre and Barmada, M Michael and Xavier, Ramnik J and Libioulle, Cécile and Tremelling, Mark and Laukens, Debby and Datta, Lisa Wu and Kistner, Emily O and Onnie, Clive M and Griffiths, Anne M and Franchimont, Denis and Lathrop, Mark and Nimmo, Elaine and Green, Todd and Mansfield, John and Zelenika, Diana and Deloukas, Panos and Taylor, Kent D and Ahmad, Tariq and de Vos, Martine and Van Gossum, André and Duerr, Richard H and Silverberg, Mark S and Nicolae, Dan L and Rotter, Jerome I and Schumm, L Philip and Cardon, Lon R and Ghori, Jilur and Heath, Simon and Dassopoulos, Themistocles and Vermeire, Severine and Sandor, Cynthia and Satsangi, Jack and Marchini, Jonathan and Gwilliam, Rhian and Louis, Edouard and Rioux, John D and Mni, Myriam and Belaiche, Jacques and Targan, Stephan R and Brant, Steven R and Murtha, Michael T and Cho, Judy H and Wellcome Trust Case Control and NIDDK IBD Genetics Consortium and Belgian-French IBD Consortium and Wellcome Trust Case Control Consortium and the NIDDK IBD Genetics Consortium and the Belgian-French IBD Consortium and the Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 08/2008, Volume 40, Issue 8, pp. 955 - 962
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data... 
GENETIC-VARIATION | CELLS | VARIANTS | COLITIS | GENETICS & HEREDITY | RISK | LARGE-SCALE | NONSYNONYMOUS SNPS | IL-23 | EXPRESSION | MULTIPLE | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome, Human | Quantitative Trait Loci | Humans | Physiological aspects | Crohn's disease | Genetic aspects | Research | Genetic susceptibility | Risk factors | Inflammatory bowel disease | Studies | Medical research | Genetics | Genomics | Crohns disease | Index Medicus
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2. Full Text A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
by Hampe, Jochen and Till, Andreas and Mathew, Christopher G and Sipos, Bence and Krawczak, Michael and Briggs, Jason and Fölsch, Ulrich R and Prescott, Natalie J and Onnie, Clive M and Günther, Simone and Lengauer, Thomas and Albrecht, Mario and Mayr, Gabriele and Platzer, Matthias and Teuber, Markus and Rosenstiel, Philip and De La Vega, Francisco M and Schreiber, Stefan and Franke, Andre and Huse, Klaus and Häsler, Robert
Nature Genetics, ISSN 1061-4036, 02/2007, Volume 39, Issue 2, pp. 207 - 211
We performed a genome-wide association study of 19,779 nonsynonymous SNPs in 735 individuals with Crohn disease and 368 controls. A total of 7,159 of these... 
VISUALIZATION | SYSTEM | GENETIC-VARIATION | INFLAMMATORY-BOWEL-DISEASE | ULCERATIVE-COLITIS | MUTATION | GENETICS & HEREDITY | POPULATIONS | NOD2 | POLYMORPHISM | APG16L | Carrier Proteins - genetics | Crohn Disease - genetics | Autophagy-Related Proteins | Genetic Predisposition to Disease | Humans | Models, Molecular | Molecular Sequence Data | Nod2 Signaling Adaptor Protein - genetics | Polymorphism, Single Nucleotide | Proteins | Genetic markers | Regression analysis | Genomics | Risk factors | Crohns disease | Index Medicus
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3. Full Text Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
by Franke, Ane and Balschun, Tobias and Karlsen, Tom H and Sventoraityte, Jurgita and Nikolaus, Susanna and Mayr, Gabriele and Domingues, Francisco S and Albrecht, Mario and Nothnagel, Michael and Ellinghaus, David and Sina, Christian and Onnie, Clive M and Weersma, Rinse K and Stokkers, Pieter C. F and Wijmenga, Cisca and Gazouli, Maria and Strachan, David and McArdle, Wendy L and Vermeire, Séverine and Rutgeerts, Paul and Rosenstiel, Philip and Krawczak, Michael and Vatn, Morten H and Mathew, Christopher G and Schreiber, Stefan and Moum, Bjørn and Jahnsen, Jørgen and Solberg, Camilla and Stray, Njål and Henriksen, Magne and Sauar, Jostein and Høie, Ole and IBSEN Study Grp and IBSEN study group and the IBSEN study group
Nature genetics, ISSN 1061-4036, 2008, Volume 40, Issue 11, pp. 1319 - 1323
Inflammatory bowel disease (IBD) typically manifests as either ulcerative colitis (UC) or Crohn's disease (CD). Systematic identification of susceptibility... 
INFLAMMATORY-BOWEL-DISEASE | METAANALYSIS | CROHNS-DISEASE | GENETICS & HEREDITY | PHENOTYPE | IL-10 GENE | IBD | TNF-ALPHA | INTERLEUKIN-10 | CYTOKINE GENE POLYMORPHISMS | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Base Sequence | Humans | Interleukin-10 - genetics | Colitis, Ulcerative - genetics | Actin-Related Protein 2-3 Complex - genetics | Mutation - genetics | Case-Control Studies | Interleukin-10 | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Risk factors | Ulcerative colitis | Data analysis | Statistical analysis | Genes | Risk | Histology | Information management | Crohns disease | Inflammatory bowel disease | Genotype & phenotype | Software packages | Bowel disease | Quality control | Genetics | Index Medicus
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4. Full Text Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
by Ouwehand, Willem and Keniry, Andrew and Fisher, Sheila A and Jewell, Derek P and Anderson, Carl A and Prescott, Natalie J and Deloukas, Panos and Blaszczyk, Katarzyna and Mansfield, John C and Mathew, Christopher G and Watkins, Nick and Drummond, Hazel and Cummings, Fraser R and Forbes, Alastair and Barrett, Jeffrey C and Ravindrarajah, Radhi and Sanderson, Jeremy and Inouye, Mike and Hunt, Sarah and Nimmo, Elaine R and Johnson, Christopher and Bumpstead, Suzannah and Hanson, Catherine E and Lobo, Alan and Massey, Dunecan and Cardon, Lon and Ewels, Philip and Satsangi, Jack and Tremelling, Mark and Gwilliam, Rhian and Carter, Martyn and Berzuini, Carlo and Lees, Charlie W and Onnie, Clive M and Parkes, Miles and Lewis, Cathryn M and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and the Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 06/2008, Volume 40, Issue 6, pp. 710 - 712
We report results of a nonsynonymous SNP scan for ulcerative colitis and identify a previously unknown susceptibility locus at ECM1. We also show that several... 
INFLAMMATORY-BOWEL-DISEASE | VARIANTS | IL23R | SUSCEPTIBILITY | GENETICS & HEREDITY | PHENOTYPE | IDENTIFICATION | GENOME-WIDE ASSOCIATION | Biomarkers - metabolism | Crohn Disease - epidemiology | Crohn Disease - genetics | Interleukin-12 Subunit p40 - genetics | Autophagy-Related Proteins | Genetic Predisposition to Disease | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Colitis, Ulcerative - genetics | Protein-Serine-Threonine Kinases - genetics | Nod2 Signaling Adaptor Protein - genetics | Colitis, Ulcerative - epidemiology | GTP-Binding Proteins - genetics | Receptors, Interleukin - genetics | Case-Control Studies | Homeodomain Proteins - genetics | Carrier Proteins - genetics | HLA-A Antigens - genetics | Polymorphism, Single Nucleotide - genetics | Cohort Studies | Physiological aspects | Crohn's disease | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Risk factors | Ulcerative colitis | Inflammatory bowel disease | Medical research | Biomedical research | Bowel disease | Colorectal cancer | Genetics | Gene loci | Regression analysis | Crohns disease | Index Medicus
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5. Full Text High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
by Eyre, Steve and Bowes, John and Diogo, Dorothee and Lee, Annette and Barton, Anne and Martin, Paul and Zhernakova, Alexana and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and Amos, Christopher I and Padyukov, Leonid and Toes, Rene E. M and Huizinga, Tom W. J and Wijmenga, Cisca and Trynka, Gosia and Franke, Lude and Westra, Harm-Jan and Alfredsson, Lars and Hu, Xinli and Sandor, Cynthia and de Bakker, Paul I. W and Davila, Sonia and Khor, Chiea Chuen and Heng, Khai Koon and Anews, Robert and Edkins, Sarah and Hunt, Sarah E and Langford, Cordelia and Symmons, Deborah and Concannon, Pat and Onengut-Gumuscu, Suna and Rich, Stephen S and Deloukas, Panos and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Arlsetig, Lisbeth and Martin, Javier and Rantapaa-Dahlqvist, Solbritt and Plenge, Robert M and Raychaudhuri, Soumya and Klareskog, Lars and Gregersen, Peter K and Worthington, Jane and Biol Rheumatoid Arthrit Genetics G and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
Using the Immunochip custom SNP array, which was designed for dense genotyping of 186 loci identified through genome-wide association studies (GWAS), we... 
INTERLEUKIN-6 RECEPTOR | RISK LOCI | METAANALYSIS | GENETICS & HEREDITY | CORONARY-HEART-DISEASE | EXPRESSION | ASSOCIATION | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Autoantibodies - blood | Humans | Male | Genetic Loci | Chromosome Mapping - instrumentation | Arthritis, Rheumatoid - genetics | Chromosome Mapping - methods | Female | Polymorphism, Single Nucleotide | Autoantibodies - genetics | Rheumatoid arthritis | Physiological aspects | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Research | Chromosomes | Studies | Medical research | Autoimmune diseases | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
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6. Full Text Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
by Burton, Paul R and Clayton, David G and Cardon, Lon R and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Ouwehand, Willem H and Samani, Nilesh J and Todd, John A and Donnelly, Peter and Barrett, Jeffrey C and Davison, Dan and Easton, Doug and Evans, David and Leung, Hin-Tak and Marchini, Jonathan L and Morris, Andrew P and Spencer, Chris C. A and Tobin, Martin D and Attwood, Antony P and Boorman, James P and Cant, Barbara and Everson, Ursula and Hussey, Judith M and Jolley, Jennifer D and Knight, Alexandra S and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V and Stevens, Helen E and Taylor, Niall C and Walters, Graham R and Walker, Neil M and Watkins, Nicholas A and Winzer, Thilo and Jones, Richard W and McArdle, Wendy L and Ring, Susan M and Strachan, David P and Pembrey, Marcus and Breen, Gerome and St. Clair, David and Caesar, Sian and Gordon-Smith, Katherine and Jones, Lisa and Fraser, Christine and Green, Elaine K and Grozeva, Detelina and Hamshere, Marian L and Holmans, Peter A and Jones, Ian R and Kirov, George and Moskvina, Valentina and Nikolov, Ivan and O'Donovan, Michael C and Owen, Michael J and Collier, David A and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H and Ferrier, I. Nicol and Ball, Stephen G and Balmforth, Anthony J and Barrett, Jennifer H and Bishop, D. Timothy and Iles, Mark M and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S and Braund, Peter S and Dixon, Richard J and Mangino, Massimo and Stevens, Suzanne and Thompson, John R and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W and Nimmo, Elaine R and Satsangi, Jack and Fisher, Sheila A and Forbes, Alastair and Lewis, Cathryn M and Onnie, Clive M and Prescott, Natalie J and Sanderson, Jeremy and Mathew, Christopher G and Barbour, Jamie and Mohiuddin, M. Khalid and Todhunter, Catherine E and Mansfield, John C and Ahmad, Tariq and Cummings, Fraser R and Jewell, Derek P and ... and Breast Canc Susceptib Collaborat and Wellcome Trust Case Control Cons and Biol RA Genet & Genom Study and Wellcome Trust Case Control Consortium and The Wellcome Trust Case Control Consortium
Nature, ISSN 0028-0836, 06/2007, Volume 447, Issue 7145, pp. 661 - 678
There is increasing evidence that genome-wide association ( GWA) studies represent a powerful approach to the identification of genes involved in common human... 
INFLAMMATORY-BOWEL-DISEASE | MULTILOCUS GENOTYPE DATA | TYPE-1 DIABETES LOCUS | MULTIDISCIPLINARY SCIENCES | RHEUMATOID-ARTHRITIS FAMILIES | MITOCHONDRIAL C-1-TETRAHYDROFOLATE SYNTHASE | AFFECTED SIBLING PAIRS | BIPOLAR DISORDER | LYMPHOID TYROSINE PHOSPHATASE | SINGLE-NUCLEOTIDE POLYMORPHISMS | CORONARY-ARTERY-DISEASE | Geography | Crohn Disease - genetics | Genetics, Population | Genetic Predisposition to Disease - genetics | Diabetes Mellitus - genetics | Chromosomes, Human - genetics | Gene Frequency | Humans | United Kingdom | Bipolar Disorder - genetics | Case-Control Studies | Genome, Human - genetics | Arthritis, Rheumatoid - genetics | Genetic Markers - genetics | Coronary Artery Disease - genetics | Hypertension - genetics | Data analysis | Disease | Genomics | Data collection | Gene loci | Epidemiology | Risk factors | Index Medicus
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