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by Ono, H
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 03/2019, Volume 20, Issue 6, p. 1317
Insulin exists in the central nervous system, where it executes two important functions in the hypothalamus: the suppression of food intake and the improvement... 
HIGH-FAT DIET | FOOD-INTAKE | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHODIESTERASE 3B PATHWAY | AGRP NEURONS | CEREBROSPINAL-FLUID | CHEMISTRY, MULTIDISCIPLINARY | BETA/NF-KAPPA-B | BODY-WEIGHT | GLUCOSE-HOMEOSTASIS | inflammation | insulin resistance | glucose metabolism | LEPTIN RESISTANCE | hypothalamus | obesity | food intake
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6165 - 12
Brown adipose tissue (BAT) plays a role in energy expenditure and is involved in nutrient metabolism. C-X-C chemokine ligand 12 (CXCL12)-CXCR4 pathway... 
CELLS | OBESITY | GENE | CHEMOKINE RECEPTOR CXCR4 | MULTIDISCIPLINARY SCIENCES | KINASE | ADIPOSE-TISSUE | FEATURES | CXCL12 protein | Adipose tissue | Body weight | Extracellular signal-regulated kinase | Energy expenditure | Oxygen consumption | mRNA | Adipocytes | Glucose | Injection | Metabolism | Kinases | Insulin | CXCR4 protein | High fat diet | Uncoupling protein 1 | Rodents | Adipose tissue (brown)
Journal Article
Nature Communications, ISSN 2041-1723, 08/2015, Volume 6, Issue 1, p. 7940
Journal Article
PLOS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0152207
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 03/2018, Volume 25, Issue 9, pp. 984 - 1001
Background: Gut microbiota play a vital role not only in the digestion and absorption of nutrients, but also in homeostatic maintenance of host immunity,... 
Gut microbiota | Obesity | Probiotics | Fecal microbiota transplantation | Type 2 diabetes mellitus | Non-alcoholic fatty liver disease | Prebiotics | CHEMISTRY, MEDICINAL | non-alcoholic fatty liver disease | RESISTIN-LIKE-MOLECULE | FATTY LIVER-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NECROSIS-FACTOR-ALPHA | NONALCOHOLIC STEATOHEPATITIS | DIET-INDUCED OBESITY | fecal microbiota transplantation | INCREASED INTESTINAL PERMEABILITY | GLUCOSE-HOMEOSTASIS | GLUCAGON-LIKE PEPTIDE-1 | FARNESOID X RECEPTOR | INSULIN-RESISTANCE | type 2 diabetes mellitus | prebiotics | PHARMACOLOGY & PHARMACY | obesity | probiotics | Diabetes Mellitus, Type 2 - microbiology | Humans | Non-alcoholic Fatty Liver Disease - microbiology | Gastrointestinal Microbiome | Non-alcoholic Fatty Liver Disease - therapy | Molecular Targeted Therapy | Obesity - microbiology | Fecal Microbiota Transplantation | Non-alcoholic Fatty Liver Disease - drug therapy | Animals | Diabetes Mellitus, Type 2 - therapy | Obesity - therapy | Probiotics - therapeutic use | Dysbacteriosis | Liver diseases | Pathogenesis | Digestive system | Therapeutic applications | Liver | Diabetes mellitus | Disorders | Membrane reactors | Transplantation | Metabolism | Immunity | Microbiota | Fatty liver | Termites | Nutrients | Diabetes mellitus (non-insulin dependent) | Digestive tract | Metabolic disorders
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 09/2019, Volume 20, Issue 19, p. 4680
Hyperuricemia has been recognized as a risk factor for insulin resistance as well as one of the factors leading to diabetic kidney disease (DKD). Since DKD is... 
diabetic kidney diseases | xanthine oxidase | glomerular damage
Journal Article
Journal Article
Hepatology Research, ISSN 1386-6346, 05/2008, Volume 38, Issue 5, pp. 474 - 483
Aim:  Intra‐arterial cisplatin appears to have high therapeutic efficacy, but this has not been studied in detail. Accordingly, we developed a fine‐powder... 
cisplatin | transcatheter arterial infusion | chemotherapy | hepatocellular carcinoma | Hepatocellular carcinoma | Chemotherapy | Cisplatin | Transcatheter arterial infusion | TRIAL | INTRAARTERIAL INFUSION | 5-FLUOROURACIL | MITOXANTRONE | THROMBOSIS | GASTROENTEROLOGY & HEPATOLOGY
Journal Article