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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 51, pp. 22231 - 22236
Inositol polyphosphate 4-phosphatase-II (INPP4B) is a regulator of the phosphoinositide 3-kinase (PI3K) signaling pathway and is implicated as a tumor... 
Cell growth | Carcinoma | Protein synthesis | Epithelial cells | Breasts | Cell lines | Breast cancer | Tumors | Phosphatidylinositols | Cancer | CELLS | PTEN LOSS | ACTIVATION | PIK3CA MUTATIONS | PATHWAY | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | ESTROGEN-RECEPTOR-ALPHA | GENE-EXPRESSION PROFILES | CARCINOMA | CORRELATE | Neoplasm Transplantation | Humans | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Loss of Heterozygosity | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - enzymology | Tumor Suppressor Proteins - genetics | Biomarkers, Tumor - metabolism | Female | Proto-Oncogene Proteins c-akt - metabolism | Gene Expression Regulation, Neoplastic - genetics | PTEN Phosphohydrolase - genetics | Phosphoric Monoester Hydrolases - genetics | Tumor Suppressor Proteins - metabolism | Signal Transduction | PTEN Phosphohydrolase - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Biomarkers, Tumor - genetics | Mice | Mice, Inbred BALB C | Phosphoric Monoester Hydrolases - metabolism | Inositol phosphates | Development and progression | Cellular signal transduction | Genetic aspects | Chemical properties | Research | Genetic regulation | Health aspects | Phosphates | Proteins | Studies | Human subjects | Estrogen | Kinases | Gene expression | Index Medicus | Biological Sciences | phosphatidylinositol 3,4-bisphosphate
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 08/2015, Volume 28, Issue 2, pp. 155 - 169
Journal Article
International Journal of Health Policy and Management, ISSN 2322-5939, 2015, Volume 4, Issue 12, pp. 799 - 804
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e17607 - e17607
Background: Hearing impairment is the most common sensory impairment in humans, affecting 1:1,000 births. We have identified an ENU generated mouse mutant,... 
INOSITOL POLYPHOSPHATE 5-PHOSPHATASES | HAIR-CELLS | HEREDITARY DEAFNESS | TARGETED DISRUPTION | INNER-EAR | PHOSPHATASE | IN-VIVO | BIOLOGY | ZEBRAFISH NRC MUTANT | SUPPORTING CELLS | PHOSPHOINOSITIDES | Hair Cells, Auditory - metabolism | Hair Cells, Auditory - pathology | Inositol Polyphosphate 5-Phosphatases | Molecular Sequence Data | Male | Vestibule, Labyrinth - metabolism | Behavior, Animal | Nerve Tissue Proteins - chemistry | Mice, Mutant Strains | Hearing Loss, Sensorineural - enzymology | Spiral Ganglion - pathology | Ethylnitrosourea | Nerve Fibers - pathology | Amino Acid Sequence | Nerve Fibers - metabolism | Phosphoric Monoester Hydrolases - genetics | Mice, Inbred C57BL | Mutagenesis - genetics | Vestibule, Labyrinth - physiopathology | Neural Conduction - physiology | Hearing Loss, Sensorineural - genetics | Spiral Ganglion - metabolism | Vestibule, Labyrinth - pathology | Mutation - genetics | Nerve Tissue Proteins - genetics | Animals | Amino Acid Substitution - genetics | Mice | Hearing Loss, Sensorineural - physiopathology | Phosphoric Monoester Hydrolases - chemistry | Enzymes | Inositol | Genetic aspects | Phosphatases | Cell death | Hearing loss | Spiral ganglion | Hair cells | Genes | Impairment | Inositol polyphosphate | Lipids | Biochemistry | Kinases | Phosphatase | Proteins | E coli | Neurodegeneration | Actin | Ion channels | Degeneration | Catalysis | Vestibular system | Hair | Phosphoinositides | Cell survival | Channel gating | Polymerization | Outer hair cells | Hearing impairment | Gene expression | Children & youth | Signaling | Hearing | Brain research | Ethyl nitrosourea | Genetic counseling | Cochlea | Mutation | Molecular biology | Inositol-1,4,5-trisphosphate 5-phosphatase | phosphoinositides | spiral ganglion | outer hair cells | Age | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 2009, Volume 10, Issue 4, pp. 260 - 272
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 34, pp. 20827 - 20840
Journal Article
Bulletin of the World Health Organization, ISSN 0042-9686, 01/2013, Volume 91, Issue 1, pp. 2 - 2
  [...]although we support making universal health care one of the post-2015 development goals, we feel that universal health coverage is not enough, as... 
PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | Health Care Reform | Universal Coverage | Humans | United Nations | Human Rights | Analysis | World health | Planning | Equal rights | National health insurance | Health services | Developing countries--LDCs | Index Medicus | Health care | Health | Organizations
Journal Article
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 01/2019, Volume 28, Issue 2, pp. 230 - 244
Abstract Polycystic kidney disease (PKD) results from excessive renal epithelial cell proliferation, leading to the formation of large fluid filled cysts which... 
OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | DOWNSTREAM TARGET | SIGNALING PATHWAY | CYST EPITHELIAL-CELLS | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | C-MYC | WNT | TRANSCRIPTION FACTOR | PHOSPHOINOSITIDE 3-KINASE
Journal Article
Journal Article