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1. Full Text Unraveling the environmental and genetic interactions in atherosclerosis: Central role of the gut microbiota
by Org, Elin and Mehrabian, Margarete and Lusis, Aldons J
Atherosclerosis, ISSN 0021-9150, 2015, Volume 241, Issue 2, pp. 387 - 399
Cardiovascular | Mucosal immune system | Host-gut microbiota interactions | Polyphenolic metabolites | Germ-free mice | Systems biology approach | Trimethylamine-N-oxide | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Bacteria - metabolism | Genetic Predisposition to Disease | Atherosclerosis - immunology | Diet - adverse effects | Atherosclerosis - genetics | Humans | Risk Factors | Gastrointestinal Tract - microbiology | Biomarkers - blood | Gene-Environment Interaction | Systems Biology | Atherosclerosis - blood | Host-Pathogen Interactions | Atherosclerosis - etiology | Gastrointestinal Tract - immunology | Bacteria - immunology | Animals | Bacteria - classification | Environment | Atherosclerosis - microbiology | Bacteria - pathogenicity | Gastrointestinal Microbiome - immunology | Disease Models, Animal | Genetic research | Insulin resistance | Genetic aspects | Metabolites | Microbiota (Symbiotic organisms) | Atherosclerosis | Index Medicus
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2. Full Text Individual diet has sex-dependent effects on vertebrate gut microbiota
by Bolnick, Daniel I and Snowberg, Lisa K and Hirsch, Philipp E and Lauber, Christian L and Org, Elin and Parks, Brian and Lusis, Aldons J and Knight, Rob and Caporaso, J. Gregory and Svanbäck, Richard
Nature communications, ISSN 2041-1723, 07/2014, Volume 5, Issue 1, pp. 4500 - 4500
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Mice - microbiology | Dysbiosis - drug therapy | Species Specificity | Humans | Gastrointestinal Tract - microbiology | Molecular Sequence Data | Male | DNA Primers - genetics | Dysbiosis - microbiology | Sequence Analysis, DNA | Smegmamorpha - microbiology | Microbiota | Phenotype | Animals | Analysis of Variance | Diet | Base Sequence | Sex Factors | RNA, Ribosomal, 16S - genetics | Female | Perches - microbiology | Index Medicus
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3. Full Text Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort
by Org, Elin and Blum, Yuna and Kasela, Silva and Mehrabian, Margarete and Kuusisto, Johanna and Kangas, Antti J and Soininen, Pasi and Wang, Zeneng and Ala-Korpela, Mika and Hazen, Stanley L and Laakso, Markku and Lusis, Aldons J
Genome Biology, ISSN 1474-7596, 04/2017, Volume 18, Issue 1, pp. 70 - 70
TMAO | Type 2 diabetes | Host-microbiota interactions | Serum metabolites | Metabolic traits | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Body Mass Index | Amino Acids - blood | Bacteria - metabolism | Glucose Tolerance Test | Microbiota - physiology | Diabetes Mellitus, Type 2 - microbiology | Humans | Middle Aged | Gastrointestinal Microbiome | Male | Metabolic Syndrome - blood | Diabetes Mellitus, Type 2 - blood | Phenotype | Metabolic Syndrome - microbiology | Lipids - blood | Bacteria - classification | Aged | Methylamines | Fatty Acids - blood | Blood Glucose - metabolism | Cohort Studies | rRNA 16S | Taxonomy | Microbiomes | Glucose | Metabolic syndrome | Body mass index | Microbiota | Metabolites | Population | Physiology | Blood pressure | Lipid metabolism | Intestinal microflora | Bioinformatics | Heart diseases | Community structure | Phenotypes | Fasting | Diabetes mellitus | Coronary artery | Fatty acids | Multiculturalism & pluralism | Serum levels | Studies | Glucose tolerance | Trimethylamine | Insulin resistance | Metabolic disorders | Index Medicus
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4. Full Text Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
by Koeth, Robert A and Wang, Zeneng and Levison, Bruce S and Buffa, Jennifer A and Org, Elin and Sheehy, Brendan T and Britt, Earl B and Fu, Xiaoming and Wu, Yuping and Li, Lin and Smith, Jonathan D and Didonato, Joseph A and Chen, Jun and Li, Hongzhe and Wu, Gary D and Lewis, James D and Warrier, Manya and Brown, J Mark and Krauss, Ronald M and Tang, W.H. Wilson and Bushman, Frederic D and Lusis, Aldons J and Hazen, Stanley L
Nature medicine, ISSN 1078-8956, 05/2013, Volume 19, Issue 5, pp. 576 - 585
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Atherosclerosis - physiopathology | Humans | Methylamines - blood | Carnitine - chemistry | Carnitine - metabolism | Cholesterol - metabolism | Choline - chemistry | Desmosterol - metabolism | Meat | Mice, Knockout | Atherosclerosis - etiology | Macrophages - metabolism | Animals | Intestines - microbiology | Time Factors | Mass Spectrometry | Female | Atherosclerosis - microbiology | Mice | Metagenome | Methylamines - metabolism | RNA - metabolism | Physiological aspects | Levocarnitine | Genetic aspects | Research | Microbiota (Symbiotic organisms) | Microbial metabolism | Biomedical research | Diet | Risk factors | Atherosclerosis | Index Medicus
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5. Full Text Sex differences and hormonal effects on gut microbiota composition in mice
by Org, Elin and Mehrabian, Margarete and Parks, Brian W and Shipkova, Petia and Liu, Xiaoqin and Drake, Thomas A and Lusis, Aldons J
Gut microbes, ISSN 1949-0976, 07/2016, Volume 7, Issue 4, pp. 313 - 322
inbred strains | gut microbiota interactions | sex-by-diet interactions | genetics | hormones | sex differences | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Mice - microbiology | Animals | Hormones - metabolism | Gastrointestinal Microbiome | Sex Factors | Gastrointestinal Tract - microbiology | Bile Acids and Salts - metabolism | Feeding Behavior | Female | Male | Mice - physiology | Index Medicus
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6. Full Text ALOX5AP gene and the PDE4D gene in a central European population of stroke patients
by Lõhmussaar, Elin and Gschwendtner, Andreas and Mueller, Jakob C and Org, Tõnis and Wichmann, Erich and Hamann, Gerhard and Meitinger, Thomas and Dichgans, Martin
Stroke (1970), ISSN 0039-2499, 04/2005, Volume 36, Issue 4, pp. 731 - 736
Genetics | Stroke | Clinical Neurology | Peripheral Vascular Disease | Neurosciences & Neurology | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Neurology | Other metabolic disorders | Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy | Biological and medical sciences | Metabolic diseases | Vascular diseases and vascular malformations of the nervous system | Amyloidosis | Medical sciences | Nervous system (semeiology, syndromes) | Haplotypes | Europe, Eastern | Cyclic Nucleotide Phosphodiesterases, Type 4 | Humans | Middle Aged | Cyclic Nucleotide Phosphodiesterases, Type 3 | Male | Risk | Case-Control Studies | Iceland | Stroke - genetics | Ischemia | Female | Odds Ratio | Microsatellite Repeats | Membrane Proteins - genetics | Gene Frequency | Risk Factors | Genotype | 3',5'-Cyclic-AMP Phosphodiesterases - genetics | Genetic Markers | Linkage Disequilibrium | Carrier Proteins - genetics | Magnetic Resonance Imaging | Regression Analysis | Edetic Acid - chemistry | 5-Lipoxygenase-Activating Proteins | Alleles | Sex Factors | Aged | Polymorphism, Single Nucleotide | Index Medicus
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7. Full Text Transmission of atherosclerosis susceptibility with gut microbial transplantation
by Gregory, Jill C and Buffa, Jennifer A and Org, Elin and Wang, Zeneng and Levison, Bruce S and Zhu, Weifei and Wagner, Matthew A and Bennett, Brian J and Li, Lin and DiDonato, Joseph A and Lusis, Aldons J and Hazen, Stanley L
The Journal of biological chemistry, ISSN 0021-9258, 02/2015, Volume 290, Issue 9, pp. 5647 - 5660
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Species Specificity | Diet - adverse effects | Humans | Male | Aorta - metabolism | Cecum - microbiology | Atherosclerosis - etiology | Mice, Inbred CBA | Female | Mice, Inbred DBA | Atherosclerosis - microbiology | Methylamines - metabolism | Microbiota - physiology | Disease Susceptibility - blood | Disease Susceptibility - complications | Mice, Inbred C57BL | Methylamines - blood | Gastrointestinal Tract - microbiology | Mice, Transgenic | Disease Susceptibility - microbiology | Mice, Inbred Strains | Mice, Inbred C3H | Mice, Knockout | Aorta - pathology | Atherosclerosis - blood | Host-Pathogen Interactions | Animals | Choline - administration & dosage | Mice, Inbred BALB C | Mice, Inbred AKR | Index Medicus | Koch's Postulate | Molecular Bases of Disease | Nutrition | Choline | Gut Microbiota | Atherosclerosis | Dyslipidemia | Phospholipid | Trimethylamine N-Oxide (TMAO) | Lipid
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8. Full Text Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk
by Zhu, Weifei and Gregory, Jill C and Org, Elin and Buffa, Jennifer A and Gupta, Nilaksh and Wang, Zeneng and Li, Lin and Fu, Xiaoming and Wu, Yuping and Mehrabian, Margarete and Sartor, R. Balfour and McIntyre, Thomas M and Silverstein, Roy L and Tang, W.H. Wilson and DiDonato, Joseph A and Brown, J. Mark and Lusis, Aldons J and Hazen, Stanley L
Cell (Cambridge), ISSN 0092-8674, 03/2016, Volume 165, Issue 1, pp. 111 - 124
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Choline - metabolism | Calcium - metabolism | Humans | Mice, Inbred C57BL | Gastrointestinal Microbiome | Methylamines - blood | Cecum - microbiology | Ferric Compounds | Thrombosis - pathology | Thrombosis - metabolism | Animals | Diet | Blood Platelets - metabolism | Chlorides | Germ-Free Life | Female | Mice | Carotid Artery Injuries - pathology | Methylamines - metabolism | Medical colleges | Metabolites | Microbiota (Symbiotic organisms) | Choline | Thrombosis | Blood clot | Risk factors | Cardiovascular agents | Index Medicus
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