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1. 5-Amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3yl)-phenyl ester (ATB-429), a hydrogen sulfide-releasing derivative of mesalamine, exerts antinociceptive effects in a model of postinflammatory hypersensitivity
by Distrutti, Eleonora and Sediari, Luca and Mencarelli, Andrea and Renga, Barbara and Orlandi, Stefano and Russo, Giuseppe and Caliendo, Giuseppe and Santagada, Vincenzo and Cirino, Giuseppe and Wallace, John L and Fiorucci, Stefano
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 2006, Volume 319, Issue 1, pp. 447 - 458
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hydrogen Sulfide - metabolism | Analgesics - pharmacology | Spinal Cord - metabolism | Rats, Wistar | Mesalamine - pharmacokinetics | Colon - drug effects | Rats | Irritable Bowel Syndrome - drug therapy | Male | Colon - metabolism | Mesalamine - pharmacology | Animals | Disulfides - pharmacokinetics | Disulfides - pharmacology | Potassium Channel Blockers - pharmacology
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2. Full Text Synthesis, antifungal activity of caffeic acid derivative esters, and their synergism with fluconazole and nystatin against Candida spp
by Sardi, Janaína de Cássia Orlandi and Gullo, Fernanda Patrícia and Freires, Irlan Almeida and Pitangui, Nayla de Souza and Segalla, Maicon Petrônio and Fusco-Almeida, Ana Marisa and Rosalen, Pedro Luiz and Regasini, Luís Octávio and Mendes-Giannini, Maria José Soares
Diagnostic microbiology and infectious disease, ISSN 0732-8893, 2016, Volume 86, Issue 4, pp. 387 - 391
Infectious Disease | Internal Medicine | Candida albicans | Antifungal | Synergism | Caffeic acid | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fluconazole - pharmacology | Humans | Caffeic Acids - pharmacology | Antifungal Agents - chemical synthesis | Candidiasis - microbiology | Esters - toxicity | Esters - chemical synthesis | Microbial Sensitivity Tests | Caffeic Acids - isolation & purification | Candida albicans - drug effects | Candida albicans - isolation & purification | Caffeic Acids - toxicity | Inhibitory Concentration 50 | Nystatin - pharmacology | Molecular Structure | Fluconazole - toxicity | Antifungal Agents - pharmacology | Cells, Cultured | Caffeic Acids - chemical synthesis | Antifungal Agents - isolation & purification | Drug Synergism | Keratinocytes - drug effects | Esters - isolation & purification | Nystatin - toxicity | Esters - pharmacology | Keratinocytes - physiology | Fluconazole | Esters | Index Medicus
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3. Full Text New structure–activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR)
by Orlandi, Francesca and Coronnello, Marcella and Bellucci, Cristina and Dei, Silvia and Guandalini, Luca and Manetti, Dina and Martelli, Cecilia and Romanelli, Maria Novella and Scapecchi, Serena and Salerno, Milena and Menif, Hayette and Bello, Ivan and Mini, Enrico and Teodori, Elisabetta
Bioorganic & medicinal chemistry, ISSN 0968-0896, 01/2013, Volume 21, Issue 2, pp. 456 - 465
N,N-Bis(cyclohexanol)amine aryl esters | MDR reversers | Pirarubicin uptake | Chemosensitizers | Doxorubicin-resistant erythroleukemia K562 cells (K562/DOX) | P-gp inhibitors | Amines - chemistry | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Drug Resistance, Neoplasm | Esters | Structure-Activity Relationship | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antineoplastic Agents - chemistry | Isomerism | Doxorubicin - toxicity | Antineoplastic Agents - toxicity | Cyclohexanols - chemistry | K562 Cells | Index Medicus | Aromatics
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4. Full Text Structure−Activity Relationships Studies in a Series of N,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors
by Martelli, Cecilia and Coronnello, Marcella and Dei, Silvia and Manetti, Dina and Orlandi, Francesca and Scapecchi, Serena and Novella Romanelli, Maria and Salerno, Milena and Mini, Enrico and Teodori, Elisabetta
Journal of medicinal chemistry, ISSN 0022-2623, 02/2010, Volume 53, Issue 4, pp. 1755 - 1762
Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Amines - chemistry | Antineoplastic Agents - chemical synthesis | Drug Resistance, Multiple - drug effects | Humans | Esters | Structure-Activity Relationship | Amines - chemical synthesis | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antineoplastic Agents - chemistry | Drug Synergism | Doxorubicin - analogs & derivatives | K562 Cells | Antineoplastic Agents - pharmacology | Amines - pharmacology | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Index Medicus
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5. Full Text Inhibition of P-glycoprotein-mediated Multidrug Resistance (MDR) by N,N-bis(cyclohexanol)amine aryl esters: Further restriction of molecular flexibility maintains high potency and efficacy
by Martelli, Cecilia and Dei, Silvia and Lambert, Catherine and Manetti, Dina and Orlandi, Francesca and Romanelli, Maria Novella and Scapecchi, Serena and Salerno, Milena and Teodori, Elisabetta
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 01/2011, Volume 21, Issue 1, pp. 106 - 109
MDR reverters | N,N-Bis(cyclohexanol)amine aryl esters | Pirarubicin uptake | Pgp inhibitors | Chemosensitizers | Doxorubicin-resistant erythroleukemia K562 cells (K562/DOX) | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Amines - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Molecular Conformation | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Esters | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Antineoplastic Agents - chemistry | Isomerism | Cyclohexanols - chemistry | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Drug Resistance, Neoplasm - drug effects | Index Medicus
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6. Full Text Chemical characterisation of the whole plant cell wall of archaeological wood: an integrated approach
by Zoia, Luca and Tamburini, Diego and Orlandi, Marco and Łucejko, Jeannette Jacqueline and Salanti, Anika and Tolppa, Eeva-Liisa and Modugno, Francesca and Colombini, Maria Perla
Analytical and bioanalytical chemistry, ISSN 1618-2642, 2017, Volume 409, Issue 17, pp. 4233 - 4245
Ionic liquids | NMR | GPC, Py(HMDS)-GC-MS | Waterlogged archaeological wood | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Ships, Ancient | Testing | Lignin | Cellulose | Aluminum sulfate | Esters | Spectroscopic analysis | Degradation | Magnetic resonance spectroscopy | Chloride | Lignocellulose | Ships | Artefacts | Oxidation | Chemical composition | Pretreatment | Carbohydrates | Solvents | Pyrolysis | Integrated approach | Preservation | Wood | Cell walls | Mass spectroscopy | Liquid chromatography | Dissolution | Chromatography | Gas chromatography | Artifacts | Pyrolysis products | Penetration | Historical structures | Acetyl chloride | Alum | NMR spectroscopy | Mass spectrometry | Index Medicus
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7. Full Text Structure−Activity Relationships Studies in a Series ofN,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors
by Martelli, Cecilia and Coronnello, Marcella and Dei, Silvia and Manetti, Dina and Orlandi, Francesca and Scapecchi, Serena and Novella Romanelli, Maria and Salerno, Milena and Mini, Enrico and Teodori, Elisabetta
Journal of medicinal chemistry, ISSN 0022-2623, 02/2010, Volume 53, Issue 4, pp. 1755 - 1762
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8. Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels
by Distrutti, Eleonora and Sediari, Luca and Mencarelli, Andrea and Renga, Barbara and Orlandi, Stefano and Antonelli, Elisabetta and Roviezzo, Fiorenza and Morelli, Antonio and Cirino, Giuseppe and Wallace, John L and Fiorucci, Stefano
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 01/2006, Volume 316, Issue 1, pp. 325 - 335
Colon - physiology | Cystathionine beta-Synthase - antagonists & inhibitors | Gene Expression - drug effects | Rats, Wistar | Air Pollutants - pharmacology | Nitric Oxide Synthase - antagonists & inhibitors | Male | ATP-Binding Cassette Transporters - agonists | Digestive System - drug effects | Rectum - physiology | Analgesics | Glyburide - pharmacology | Dilatation | Behavior, Animal - drug effects | Colitis - psychology | NG-Nitroarginine Methyl Ester - pharmacology | Hydrogen Sulfide - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Pain Measurement - drug effects | Potassium Channels, Inwardly Rectifying - agonists | Hydrogen Sulfide - blood | Cystathionine gamma-Lyase - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | Animals | KATP Channels | Genes, fos - genetics | Index Medicus
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9. Full Text Parametrization of Non-covalent Interactions for Transition State Interrogation Applied to Asymmetric Catalysis
by Orlandi, Manuel and Coelho, Jaime A. S and Hilton, Margaret J and Toste, F. Dean and Sigman, Matthew S
Journal of the American Chemical Society, ISSN 0002-7863, 05/2017, Volume 139, Issue 20, pp. 6803 - 6806
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Propanols - chemistry | Thermodynamics | Esters - chemistry | Stereoisomerism | Boronic Acids - chemistry | Catalysis | Kinetics | Esters - chemical synthesis | Research | Intermolecular forces | Transition state (Chemistry) | Analysis | Index Medicus
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10. Full Text Epithelium integrity is crucial for the relaxant activity of brain natriuretic peptide in human isolated bronchi
by Matera, Maria G and Calzetta, Luigino and Passeri, Daniela and Facciolo, Francesco and Rendina, Erino A and Page, Clive and Cazzola, Mario and Orlandi, Augusto
British journal of pharmacology, ISSN 0007-1188, 08/2011, Volume 163, Issue 8, pp. 1740 - 1754
brain natriuretic peptide | inducible NOS | nitric oxide | acetylcholine | natriuretic peptide receptor A | bronchodilatation | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Acetylcholine - biosynthesis | Epithelial Cells - drug effects | Humans | Middle Aged | Receptor, Muscarinic M2 - drug effects | Male | Natriuretic Peptide, Brain - physiology | Nitric Oxide Synthase Type II - antagonists & inhibitors | Respiratory Hypersensitivity - physiopathology | Female | Receptor, Muscarinic M2 - antagonists & inhibitors | Bronchi - physiology | Cell Culture Techniques | Bronchi - cytology | Cholinergic Agonists - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Epithelium - drug effects | Nitric Oxide - biosynthesis | Histamine - pharmacology | Receptors, Atrial Natriuretic Factor - metabolism | Respiratory Hypersensitivity - chemically induced | Enzyme Inhibitors - pharmacology | Muscle Tonus - drug effects | Carbachol - pharmacology | Epithelium - physiology | Receptors, Atrial Natriuretic Factor - drug effects | Histamine Agonists - pharmacology | Epithelium - injuries | Index Medicus | Research Papers
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11. Full Text Personalized Medicine and the Contradictions and Limits of First-Generation Deescalation Trials in Patients With Human Papillomavirus–Positive Oropharyngeal Cancer
by Orlandi, Ester and Licitra, Lisa
JAMA otolaryngology-- head & neck surgery, ISSN 2168-6181, 11/2017, Volume 144, Issue 2, pp. 99 - 100
Otorhinolaryngology | Life Sciences & Biomedicine | Surgery | Science & Technology | Index Medicus | Abridged Index Medicus
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12. Full Text Horseradish peroxidase catalyzed oxidative cross-coupling reactions: the synthesis of ‘unnatural’ dihydrobenzofuran lignans
by Saliu, Francesco and Tolppa, Eeva-Liisa and Zoia, Luca and Orlandi, Marco
Tetrahedron letters, ISSN 0040-4039, 07/2011, Volume 52, Issue 30, pp. 3856 - 3860
Dihydrobenzofuran lignans | Horseradish peroxidase | Radical cross-coupling reaction | Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives | Organic chemistry | Chemistry | Free radicals chemistry | Heterocyclic compounds | Reactivity and mechanisms | Exact sciences and technology | Preparations and properties | Peroxidase | Synthesis (chemistry) | Lignans | Tetrahedrons | Chemical reactions | Esters | Biochemistry | Biomimetic materials
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13. Full Text Enantioselective Organocatalytic Reduction of β‐Trifluoromethyl Nitroalkenes: An Efficient Strategy for the Synthesis of Chiral β‐Trifluoromethyl Amines
by Massolo, Elisabetta and Benaglia, Maurizio and Orlandi, Manuel and Rossi, Sergio and Celentano, Giuseppe
Chemistry : a European journal, ISSN 0947-6539, 02/2015, Volume 21, Issue 9, pp. 3589 - 3595
chiral fluorinated amines | trifluoromethyl derivatives | nitroalkenes | bifunctional catalyst | reduction | Reduction | Trifluoromethyl derivatives | Bifunctional catalyst | Nitroalkenes | Chiral fluorinated amines | Amines - chemistry | Alkenes - chemistry | Hydrocarbons, Fluorinated - chemical synthesis | Stereoisomerism | Nitro Compounds - chemistry | Esters | Hydrocarbons, Fluorinated - chemistry | Nitro Compounds - chemical synthesis | Molecular Structure | Catalysis | Thiourea - chemistry | Alkenes - chemical synthesis | Index Medicus | Enrichment | Amines | Catalysts | Precursors | Strategy | Derivatives
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14. Full Text Moderately accelerated intensity‐modulated radiation therapy using simultaneous integrated boost: Practical reasons or evidence‐based choice? A critical appraisal of literature
by De Felice, Francesca and Bonomo, Pierluigi and Sanguineti, Giuseppe and Orlandi, Ester
Head & neck, ISSN 1043-3074, 11/2020, Volume 42, Issue 11, pp. 3405 - 3414
radiotherapy | simultaneous integrated boost | intensity modulated radiotherapy | head and neck cancer | squamous cell carcinoma | Otorhinolaryngology | Life Sciences & Biomedicine | Surgery | Science & Technology | Squamous cell carcinoma | Chemotherapy | Analysis | Radiation | Radiotherapy | Evidence-based medicine | Cancer | Head and neck cancer | Radiation therapy | Cisplatin | Morbidity | Index Medicus
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15. Full Text Comment on 'Human papillomavirus association is the most important predictor for surgically treated patients with oropharyngeal cancer'
by Bossi, Paolo and Granata, Roberta and Orlandi, Ester and Licitra, Lisa
British journal of cancer, ISSN 0007-0920, 02/2018, Volume 118, Issue 3, pp. e5 - e5
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus | Letter to the Editor
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