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1. Full Text Identification of six new susceptibility loci for invasive epithelial ovarian cancer
by Kuchenbaecker, Karoline and Ramus, Susan and Tyrer, Jonathan and Lee, Anew and Shen, Howard C and Beesley, Jonathan and Lawrenson, Kate and McGuffog, Lesley and Healey, Sue and Lee, Janet M and Spindler, Tassja J and Lin, Yvonne G and Pejovic, Tanja and Bean, Yukie and Li, Qiyuan and Coetzee, Simon and Hazelett, Dennis and Miron, Alexander and Southey, Melissa and Terry, Mary Beth and Goldgar, David and Buys, Sauna and Janavicius, Ramunas and Dorfling, Cecilia and Rensburg, Elizabeth and Neuhausen, Susan and Ding, Yuan and Hansen, Thomas and Jønson, Lars and Gerdes, Anne-Marie and Ejlertsen, Bent and Barrowdale, Daniel and Dennis, Joe and Benítez, Javier and Osorio, Ana and Garcia, Maria Jose and Komenaka, Ian and Weitzel, Jeffrey and Ganschow, Pamela and Peterlongo, Paolo and Bernard, Loris and Viel, Alessana and Bonnani, Bernardo and Peissel, Bernard and Manoukian, Siranoush and Radice, Paolo and Papi, Laura and Ottini, Laura and Fostira, Florentia and Konstantopoulou, I and Garber, Judy and Frost, Debra and Perkins, Jo and Platte, Radka and Ellis, Steve and Godwin, Anew K and Schmutzler, Rita and Meindl, Alfons and Engel, Christoph and Sutter, Christian and Sinilnikova, Olga and Damiola, Francesca and Mazoyer, Sylvie and Stoppa-Lyonnet, Dominique and Claes, Kathleen B.M and De Leeneer, Kim and Kirk, Judy and Roiguez, Gustavo and Piedmonte, Marion and O'Malley, David M and Hoya, Miguel and Caldes, Trinidad and Aittomäki, Kristiina and Nevanlinna, Heli and Margriet, J. Collée and Rookus, Matti and Oosterwijk, Jan and Tihomirova, Laima and Tung, Nadine and Hamann, Ute and Isaccs, Claudine and Tischkowitz, Marc and Imyanitov, Evgeny and Caligo, Maria and Campbell, Ian and Hogervorst, Frans and Olah, E and Díez, Orland and Blanco, Ignacio and Brunet, Joan and Lazaro, Conxi and Pujana, Miguel and Jakubowska, Anna and Gronwald, Jacek and Lubinski, Jan and Sukiennicki, Grzegorz and Barkardottir, Rosa and Plante, Marie and Simard, Jacques and Soucy, Penny and ... and KConFab Investigators and EMBRACE and GEMO Study Collaborators and Breast Cancer Family Registry and Australian Ovarian Canc Study Grp and HEBON and Consortium Invest Modifiers BRCA1 and Australian Canc Study Ovarian Canc and Australian Cancer Study (Ovarian Cancer Investigators) and Australian Ovarian Cancer Study Group and Consortium of Investigators of Modifiers of BRCA1 and BRCA2 and the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Diagnostikcentrum and Klinisk patologi och klinisk genetik and Avdelningen för kliniska vetenskaper and Hälsouniversitetet
Nature Genetics, ISSN 1061-4036, 01/2015, Volume 47, Issue 2, pp. 164 - 171
textabstractGenome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer (EOC) susceptibility alleles. The pattern of association at... 
BRCA2 MUTATION CARRIERS | BREAST-CANCER | COMMON VARIANTS | METAANALYSIS | HIGH-RISK | MYOPODIN | GENETICS & HEREDITY | HUMAN ELG1 | ABO BLOOD-GROUP | SINGLE NUCLEOTIDE POLYMORPHISMS | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Humans | Genotype | Risk | Ovarian Neoplasms - genetics | Young Adult | BRCA1 Protein - genetics | Neoplasms, Glandular and Epithelial - genetics | Adolescent | Alleles | Carcinoma, Ovarian Epithelial | Adult | Female | Heterozygote | Polymorphism, Single Nucleotide | Mutation | Genome-Wide Association Study - methods | Quantitative Trait Loci | BRCA2 Protein - genetics | Genes, Reporter | Quantitative trait loci | Genetic aspects | Identification and classification | Health aspects | Ovarian cancer | Haplotypes | Accuracy | Population | Hormone replacement therapy | Genomes | Meta-analysis | Index Medicus | Cèl·lules epitelials | Càncer d'ovari | Developmental genetics | Human genome | Epithelial cells | Genètica del desenvolupament | Nucleotides | Genoma humà | Nucleòtids | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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2. Full Text Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
by Bojesen, Stig E and Pooley, Karen A and Johnatty, Sharon E and Beesley, Jonathan and Michailidou, Kyriaki and Tyrer, Jonathan P and Edwards, Stacey L and Pickett, Hilda A and Shen, Howard C and Smart, Chanel E and Hillman, Kristine M and Mai, Phuong L and Lawrenson, Kate and Stutz, Michael D and Lu, Yi and Karevan, Rod and Woods, Nicholas and Johnston, Rebecca L and French, Juliet D and Chen, Xiaoqing and Weischer, Maren and Nielsen, Sune F and Maranian, Melanie J and Ghoussaini, Maya and Ahmed, Shahana and Baynes, Caroline and Bolla, Manjeet K and Wang, Qin and Dennis, Joe and McGuffog, Lesley and Barrowdale, Daniel and Lee, Anew and Healey, Sue and Lush, Michael and Tessier, Daniel C and Vincent, Daniel and Bacot, Françis and Vergote, Ignace and Lambrechts, Sanina and Despierre, Evelyn and Risch, Harvey A and González-Neira, Anna and Rossing, Mary Anne and Pita, Guillermo and Doherty, Jennifer A and Alvarez, Nuria and Larson, Melissa C and Fridley, Brooke L and Schoof, Nils and Chang-Claude, Jenny and Cicek, Mine S and Peto, Julian and Kalli, Kimberly R and Broeks, Annegien and Armasu, Sebastian M and Schmidt, Marjanka K and Braaf, Linde M and Winterhoff, Boris and Nevanlinna, Heli and Konecny, Gottfried E and Lambrechts, Diether and Rogmann, Lisa and Guénel, Pascal and Teoman, Attila and Milne, Roger L and Garcia, Joaquin J and Cox, Angela and Shridhar, Vijayalakshmi and Burwinkel, Barbara and Marme, Frederik and Hein, Rebecca and Sawyer, Elinor J and Haiman, Christopher A and Wang-Gohrke, Shan and Anulis, Irene L and Moysich, Kirsten B and Hopper, John L and Odunsi, Kunle and Lindblom, Annika and Giles, Graham G and Brenner, Hermann and Simard, Jacques and Lurie, Galina and Fasching, Peter A and Carney, Michael E and Radice, Paolo and Wilkens, Lynne R and Swerdlow, Anthony and Goodman, Marc T and Brauch, Hiltrud and Garcia-Closas, Montserrat and Hillemanns, Peter and Winqvist, Robert and Dürst, Matthias and Devilee, Peter and Runnebaum, Ingo and Jakubowska, Anna and Lubinski, Jan and Mannermaa, Arto and Butzow, Ralf and ... and Gene Environm Interactimi Breast and Kathleen Cuningham Fdn Consortium and Australian Ovarian Canc Study and Epidemiological Study BRCA1 and Hereditary Breast Ovarian Canc Res and Genetic Modifiers Canc Risk BRCA1 and Australian Canc Study and Swedish Breast Canc Study SWE-BRCA and Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) and Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Gene Environment Interaction and Breast Cancer (GENICA) and Swedish Breast Cancer Study (SWE-BRCA) and Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE) and Australian Ovarian Cancer Study and Australian Cancer Study and Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) and The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Medicinska fakulteten and Umeå universitet and Institutionen för strålningsvetenskaper
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 371 - 384
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of multiple cancers. Using the Illumina custom genotyping array iCOGs, we... 
BUCCAL CELLS | GENETIC-VARIATION | COMMON VARIANTS | TERT-CLPTM1L LOCUS | REVERSE-TRANSCRIPTASE | SEQUENCE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | POLYMORPHISM | FIBROBLASTS | GENOME-WIDE ASSOCIATION | Luciferases - metabolism | Alternative Splicing | Oligonucleotide Array Sequence Analysis | Humans | Breast Neoplasms - etiology | Genetic Loci - genetics | Ovarian Neoplasms - pathology | Gene Expression Profiling | Case-Control Studies | DNA Methylation | Telomerase - genetics | Female | Ovarian Neoplasms - etiology | Real-Time Polymerase Chain Reaction | Telomere - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | RNA, Messenger - genetics | Risk Factors | Genotype | Reverse Transcriptase Polymerase Chain Reaction | Breast Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Biomarkers, Tumor - genetics | Chromatin - genetics | Breast cancer | Genetic aspects | Research | Single nucleotide polymorphisms | Risk factors | Ovarian cancer | Genetics | Mutation | Index Medicus | Càncer de mama | Càncer d'ovari | Telòmer | Telomere | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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3. Full Text PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
by Southey, Melissa C and Goldgar, David E and Winqvist, Robert and Pylkäs, Katri and Couch, Fergus and Tischkowitz, Marc and Foulkes, William D and Dennis, Joe and Michailidou, Kyriaki and van Rensburg, Elizabeth J and Heikkinen, Tuomas and Nevanlinna, Heli and Hopper, John L and Dörk, Thilo and Claes, Kathleen BM and Reis-Filho, Jorge and Teo, Zhi Ling and Radice, Paolo and Catucci, Irene and Peterlongo, Paolo and Tsimiklis, Helen and Odefrey, Fabrice A and Dowty, James G and Schmidt, Marjanka K and Broeks, Annegien and Hogervorst, Frans B and Verhoef, Senno and Carpenter, Jane and Clarke, Christine and Scott, Rodney J and Fasching, Peter A and Haeberle, Lothar and Ekici, Arif B and Beckmann, Matthias W and Peto, Julian and dos-Santos-Silva, Isabel and Fletcher, Olivia and Johnson, Nichola and Bolla, Manjeet K and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Federik and Burwinkel, Barbara and Yang, Rongxi and Guénel, Pascal and Truong, Thérèse and Menegaux, Florence and Sanchez, Marie and Bojesen, Stig and Nielsen, Sune F and Flyger, Henrik and Benitez, Javier and Zamora, M Pilar and Perez, Jose Ignacio Arias and Menéndez, Primitiva and Anton-Culver, Hoda and Neuhausen, Susan and Ziogas, Argyrios and Clarke, Christina A and Brenner, Hermann and Arndt, Volker and Stegmaier, Christa and Brauch, Hiltrud and Brüning, Thomas and Ko, Yon-Dschun and Muranen, Taru A and Aittomäki, Kristiina and Blomqvist, Carl and Bogdanova, Natalia V and Antonenkova, Natalia N and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and Kataja, Vesa and Kosma, Veli-Matti and Hartikainen, Jaana M and Spurdle, Amanda B and Investigators, kConFab and Wauters, Els and Smeets, Dominiek and Beuselinck, Benoit and Floris, Giuseppe and Chang-Claude, Jenny and Rudolph, Anja and Seibold, Petra and Flesch-Janys, Dieter and Olson, Janet E and Vachon, Celine and Pankratz, Vernon S and McLean, Catriona and Haiman, Christopher A and Henderson, Brian E and Schumacher, Fredrick and Le Marchand, Loic and Kristensen, Vessela and Alnæs, Grethe Grenaker and Zheng, Wei and Hunter, David J and ... and Australian Ovarian Canc Study Grp and kConFab Investigators and Australian Ovarian Cancer Study Group
Journal of Medical Genetics, ISSN 0022-2593, 12/2016, Volume 53, Issue 12, pp. 800 - 811
BackgroundThe rarity of mutations in PALB2, CHEK2 and ATM make it difficult to estimate precisely associated cancer risks. Population-based family studies have... 
GENE | BRCA2-INTERACTING PROTEIN | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | MUTATIONS | BRCA1 | BREAST | Prostatic Neoplasms - metabolism | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Male | Risk | Case-Control Studies | Breast Neoplasms - metabolism | Ovarian Neoplasms - epidemiology | Prostatic Neoplasms - epidemiology | Ovarian Neoplasms - genetics | Checkpoint Kinase 2 - genetics | Breast Neoplasms - genetics | Prostatic Neoplasms - genetics | Tumor Suppressor Proteins - genetics | Female | Ovarian Neoplasms - metabolism | Mutation | Ataxia Telangiectasia Mutated Proteins - genetics | Nuclear Proteins - genetics | Fanconi Anemia Complementation Group N Protein | Breast Neoplasms - epidemiology | Breast cancer | Genetic aspects | Research | BRCA mutations | Genetic variation | Risk factors | Index Medicus | Cancer: breast | Cancer: ovary | Genetics | cancer predisposition | 1507 | Cancer Genetics | Cancer: prostate | 1506
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4. Full Text Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
by Lawrenson, Kate and Kar, Siddhartha and McCue, Karen and Kuchenbaeker, K and Michailidou, Kyriaki and Tyrer, Jonathan and Beesley, Jonathan and Ramus, Susan and Li, Q and Delgado, M.K and Lee, Janet M and Aittomäki, Kristiina and Anulis, Irene and Anton-Culver, Hoda and Arndt, V and Arun, Banu and Arver, Brita Wasteson and Bandera, Elisa and Barile, Monica and Barkardottir, R.B and Barrowdale, Daniel and Beckmann, Matthias and Benítez, Javier and Berchuck, Anew and Bisogna, Maria and Bjorge, Line and Blomqvist, Carl and Blot, William and Bogdanova, Natalia and Bojesen, A and Bojesen, Stig and Bolla, Manjeet K and Bonnani, Bernardo and Borresen-Dale, Anne-Lise and Brauch, Hiltrud and Brennan, Paul and Brenner, Hermann and Bruinsma, Fiona and Brunet, Joan and Buhari, Shaik Ahmad Bin Syed and Burwinkel, Barbara and Butzow, Ralf and Buys, Sauna and Cai, Qiuyin and Caldes, Trinidad and Campbell, Ian and Canniotto, R and Chang-Claude, Jenny and Chiquette, J and Choi, J.-Y and Claes, Kathleen B.M and Cook, Linda S and Cox, Angela and Cramer, Daniel and Cross, Simon and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and Damiola, Francesca and Dansonka-Mieszkowska, Agnieszka and Darabi, Hatef and Dennis, Joe and Devilee, Peter and Díez, Orland and Doherty, Jennifer A and Domchek, Susan and Dorfling, Cecilia and Dörk, Thilo and Dumont, Martine and Ehrencrona, Hans and Ejlertsen, Bent and Ellis, Steve and Engel, Christoph and Lee, Eunjung and Evans, D.G and Fasching, Peter and Feliubadaló, L and Figueroa, Jonine and Flesch-Janys, Dieter and Fletcher, Olivia and Flyger, Henrik and Foretova, Lenka and Fostira, Florentia and Foulkes, William and Fridley, Brooke and Friedman, Eitan and Frost, Debra and Gambino, G and Ganz, Patricia A and Garber, Judy and García-Closas, Montserrat and Gentry-Maharaj, Aleksana and Ghoussaini, Maya and Giles, Graham and Glasspool, Rosalind and Godwin, Anew K and Goldberg, Mark and Goldgar, David and González-Neira, Anna and Goode, Ellen and ... and KConFab Investigators and Australian Ovarian Canc Study Grp and GEMO Study Collaborators and EMBRACE and Hereditary Breast & Ovarian Canc R and Australian Ovarian Cancer Study Group and Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Diagnostikcentrum and Klinisk patologi och klinisk genetik and Avdelningen för cellbiologi
Nature Communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12675 - 12675
textabstractA locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and... 
BRCA2 MUTATION CARRIERS | COMMON VARIANTS | IDENTIFIES 3 | GWAS | INVESTIGATORS | EPITHELIAL-CELLS | MODIFIERS | GENE | MULTIDISCIPLINARY SCIENCES | GENOME-WIDE ASSOCIATION | REVEALS | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | RNA, Messenger - genetics | Asian Continental Ancestry Group - genetics | Genotype | RNA, Messenger - metabolism | Ovarian Neoplasms - genetics | Chromosomes, Human, Pair 19 - genetics | Breast Neoplasms - genetics | Alleles | Female | Polymorphism, Single Nucleotide | African Continental Ancestry Group - genetics | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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5. Full Text Previous lung diseases and lung cancer risk: A pooled analysis from the international lung cancer consortium
by Brenner, Darren R and Boffetta, Paolo and Duell, Eric J and Bickeböller, Heike and Rosenberger, Albert and McCormack, Valerie and Muscat, Joshua E and Yang, Ping and Wichmann, H.-Erich and Brueske-Hohlfeld, Irene and Schwartz, Ann G and Cote, Michele L and Tjonneland, Anne and Friis, Soren and Le Marchand, Loic and Zhang, Zuo-Feng and Morgenstern, Hal and Szeszenia-Dabrowska, Neonila and Lissowska, Jolanta and Zaridze, David and Rudnai, Peter and Fabianova, Eleonora and Foretova, Lenka and Janout, Vladimir and Bencko, Vladimir and Schejbalova, Miriam and Brennan, Paul and Mates, Ioan N and Lazarus, Philip and Field, John K and Raji, Olaide and McLaughlin, John R and Liu, Geoffrey and Wiencke, John and Neri, Monica and Ugolini, Donatella and Andrew, Angeline S and Lan, Qing and Hu, Wei and Orlow, Irene and Park, Bernard J and Hung, Rayjean J
American Journal of Epidemiology, ISSN 0002-9262, 10/2012, Volume 176, Issue 7, pp. 573 - 585
To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and tuberculosis) in the development of lung cancer, the authors... 
lung diseases | lung neoplasms | pneumonia | pulmonary disease | tuberculosis | bronchitis | meta-analysis | chronic obstructive | chronic | emphysema | RESIDENTIAL RADON | VALIDATION | PREDICTION MODEL | SMOKING | OBSTRUCTIVE PULMONARY-DISEASE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INFLAMMATION | NEVER-SMOKERS | ASSOCIATION | EPIDEMIOLOGY | EXPOSURE | Pulmonary Emphysema - complications | Bronchitis, Chronic - complications | Lung Neoplasms - etiology | Humans | Risk Factors | Self Report | Proportional Hazards Models | Pneumonia - complications | Logistic Models | Risk | Tuberculosis, Pulmonary - complications | Prevention | Causes of | Influence | Research | Lung cancer | Lung diseases | Tuberculosis | Risk factors | Meta-analysis | Smoking | Index Medicus | Systematic Reviews and Meta- and Pooled Analyses
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