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1. Full Text Response to the Letter to the Editor on : "A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets," Cancer Lett. 2016 Nov 28;382(2):203-214
by Orsulic, Sandra, Dr
Cancer letters, ISSN 0304-3835, 2017, Volume 393, pp. 127 - 128
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Fibroblasts | Neoplasms - genetics | Humans | Oncogenes | Index Medicus
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2. Full Text Abstract 1009: Reciprocal roles of cancer associated fibroblasts and CD4+ T cells in ovarian cancer progression
by Hu, Ye and Orsulic, Sandra
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1009 - 1009
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3. Full Text Inflammation is a key contributor to ovarian cancer cell seeding
by Jia, Dongyu and Nagaoka, Yoshiko and Katsumata, Makoto and Orsulic, Sandra
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 12394 - 7
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Atrophy | Inflammation - pathology | Animals | Neoplasm Seeding | Biopsy | Humans | Ovarian Neoplasms - pathology | Cell Line, Tumor | Female | Mice | Ovulation | Disease Models, Animal | Wound healing | Menopause | Aging | Inflammation | Fallopian tube | Ovarian cancer | Post-menopause | Index Medicus
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4. Full Text Can molecular subtyping be used to triage women with advanced ovarian cancer to Primary Debulking Surgery or Neoadjuvant Chemotherapy?
by Orsulic, Sandra and Karlan, Beth Y
Gynecologic oncology, ISSN 0090-8258, 02/2019, Volume 152, Issue 2, pp. 221 - 222
Oncology | Life Sciences & Biomedicine | Obstetrics & Gynecology | Science & Technology | Index Medicus
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5. Full Text The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
by Gasser, Stephan and Orsulic, Sandra and Brown, Eric J and Raulet, David H
Nature (London), ISSN 0028-0836, 08/2005, Volume 436, Issue 7054, pp. 1186 - 1190
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Immunobiology | Organs and cells involved in the immune response | Analysis of the immune response. Humoral and cellular immunity | DNA Damage - drug effects | Protein Kinases - metabolism | NK Cell Lectin-Like Receptor Subfamily K | Phosphorylation | DNA Replication - drug effects | Humans | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | Cell Transformation, Neoplastic - metabolism | Up-Regulation - drug effects | Animals | Aphidicolin - pharmacology | Immune System - metabolism | Immunity, Innate - physiology | Receptors, Natural Killer Cell | Cell Line, Tumor | Fibroblasts | Checkpoint Kinase 1 | Ligands | Mice | Kinetics | Protein-Serine-Threonine Kinases - metabolism | Receptors, Immunologic - metabolism | Proteins | T cell receptors | Gene expression | DNA damage | Rodents | Immune system | Index Medicus
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6. Full Text Editorial: The Tumor Microenvironment: Recent Advances and Novel Therapeutic Approaches
by Korkaya, Hasan and Orsulic, Sandra
Frontiers in cell and developmental biology, ISSN 2296-634X, 09/2020, Volume 8, pp. 586176 - 586176
Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | TAM | CAF | CSC | MDSC | tumor microenvironment | ECM
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7. Full Text Inhibitor of apoptosis proteins (IAPs) mediate collagen type XI alpha 1-driven cisplatin resistance in ovarian cancer
by Rada, Miran and Nallanthighal, Sameera and Cha, Jennifer and Ryan, Kerry and Sage, Jessica and Eldred, Catherine and Ullo, Maria and Orsulic, Sandra and Cheon, Dong-Joo
Oncogene, ISSN 0950-9232, 08/2018, Volume 37, Issue 35, pp. 4809 - 4820
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Prognosis | Humans | Ovarian Neoplasms - pathology | Cisplatin - pharmacology | Collagen Type XI - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Female | Signal Transduction - physiology | Inhibitor of Apoptosis Proteins - metabolism | Mice | Ovarian Neoplasms - metabolism | Apoptosis - physiology | Drug Resistance, Neoplasm - physiology | Gene Expression Regulation, Neoplastic - physiology | Ovarian Neoplasms - drug therapy | Cellular proteins | Care and treatment | Development and progression | Genetic aspects | Drug resistance | Gene expression | Health aspects | Ovarian cancer | NF-κB protein | IAP protein | Animal models | Therapeutic applications | XIAP protein | AKT protein | Cisplatin | 1-Phosphatidylinositol 3-kinase | Signal transduction | Collagen | Xenografts | Extracellular matrix | Apoptosis | Index Medicus
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8. Full Text Identification of Infertility-Associated Topologically Important Genes Using Weighted Co-expression Network Analysis
by Wu, Jingni and Xia, Xiaomeng and Hu, Ye and Fang, Xiaoling and Orsulic, Sandra
Frontiers in genetics, ISSN 1664-8021, 2021, Volume 12, pp. 580190 - 580190
Gene expression | Genes | Analysis | Infertility | Protein-protein interactions | hub lncRNA | hub mRNA | biomarker | WGCNA | infertility in endometriosis
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9. Full Text A paradoxical correlation of cancer-associated fibroblasts with survival outcomes in B-cell lymphomas and carcinomas
by Haro, Marcela and Orsulic, Sandra
Frontiers in cell and developmental biology, ISSN 2296-634X, 08/2018, Volume 6, pp. 98 - 98
Cancer-associated fibroblasts | DLBCL | Gene signature | CAFs | Tumor microenvironment | B cells | B-cell lymphoma | Ovarian cancer | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Fibroblasts | Lymphomas | Genetic aspects | Research | cancer-associated fibroblasts | gene signature
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10. Full Text The PARP1 inhibitor BMN 673 exhibits immunoregulatory effects in a Brca1−/− murine model of ovarian cancer
by Huang, Jing and Wang, Lei and Cong, Zhongyi and Amoozgar, Zohreh and Kiner, Evgeny and Xing, Deyin and Orsulic, Sandra and Matulonis, Ursula and Goldberg, Michael S
Biochemical and biophysical research communications, ISSN 0006-291X, 08/2015, Volume 463, Issue 4, pp. 551 - 556
Immune microenvironment | PARP1 | BMN 673 | Ovarian cancer | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Enzyme Inhibitors - pharmacology | Ovarian Neoplasms - pathology | Poly(ADP-ribose) Polymerase Inhibitors | Mice, Knockout | Ovarian Neoplasms - genetics | Phthalazines - pharmacology | Animals | Flow Cytometry | Female | Mice | Genes, BRCA1 | Poly (ADP-Ribose) Polymerase-1 | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Ovarian Neoplasms - immunology | Index Medicus
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11. Full Text A mouse model for the molecular characterization of Brca1-associated ovarian carcinoma
by Xing, Deyin and Orsulic, Sandra
Cancer research (Chicago, Ill.), ISSN 0008-5472, 09/2006, Volume 66, Issue 18, pp. 8949 - 8953
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | Female genital diseases | Paclitaxel - pharmacology | Epithelial Cells - drug effects | Ovarian Neoplasms - pathology | Mice, Transgenic | Ovary - physiology | Cisplatin - pharmacology | Genes, myc | Tumor Suppressor Protein p53 - deficiency | Tumor Suppressor Protein p53 - genetics | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Epithelial Cells - physiology | Genes, p53 | Proto-Oncogene Proteins c-myc - physiology | Animals | Cell Transformation, Neoplastic - genetics | Female | Ovary - drug effects | Mice | Proto-Oncogene Proteins c-myc - genetics | DNA Damage | Genes, BRCA1 | BRCA1 Protein - deficiency | Disease Models, Animal | Index Medicus
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12. Full Text A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
by Jia, Dongyu and Liu, Zhenqiu and Deng, Nan and Tan, Tuan Zea and Huang, Ruby Yun-Ju and Taylor-Harding, Barbie and Cheon, Dong-Joo and Lawrenson, Kate and Wiedemeyer, Wolf R and Walts, Ann E and Karlan, Beth Y and Orsulic, Sandra
Cancer letters, ISSN 0304-3835, 2016, Volume 382, Issue 2, pp. 203 - 214
Hematology, Oncology and Palliative Medicine | Cancer-associated fibroblasts | Myofibroblasts | Tumor microenvironment | Pan-cancer | Therapeutic targets | Life Sciences & Biomedicine | Oncology | Science & Technology | Cancer-Associated Fibroblasts - metabolism | Coculture Techniques | Humans | Actins - metabolism | Gene Expression Regulation, Neoplastic | Ovarian Neoplasms - pathology | Transcriptome | Databases, Genetic | Neoplasms, Glandular and Epithelial - metabolism | Tumor Microenvironment | Myofibroblasts - metabolism | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Collagen Type I - genetics | Neoplasm Grading | Time Factors | Biomarkers, Tumor - metabolism | Ovarian Neoplasms - metabolism | Myofibroblasts - pathology | Neoplasms, Glandular and Epithelial - pathology | Collagen Type I - metabolism | Kaplan-Meier Estimate | Neoplasms, Glandular and Epithelial - therapy | Gene Expression Profiling - methods | Disease-Free Survival | Cancer-Associated Fibroblasts - pathology | Carcinoma, Ovarian Epithelial | Cell Line, Tumor | Ovarian Neoplasms - therapy | Biomarkers, Tumor - genetics | Neoplasm Staging | Genetic aspects | Health aspects | Genes | Cancer | Index Medicus | cancer-associated fibroblasts | pan-cancer | therapeutic targets | tumor microenvironment | myofibroblasts
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13. Full Text Argininosuccinate synthetase (ASS) deficiency in high-grade pulmonary neuroendocrine carcinoma: an opportunity for personalized targeted therapy
by Walts, Ann E and Walts, Ann E and Bomalaski, John S and Bomalaski, John S and Ines, Delma and Ines, Delma and Orsulic, Sandra and Orsulic, Sandra
Journal of cancer research and clinical oncology, ISSN 0171-5216, 8/2015, Volume 141, Issue 8, pp. 1363 - 1369
Small cell lung cancer | Medicine & Public Health | Hematology | Pegylated arginine deiminase (ADI-PEG20) | Neuroendocrine carcinoma | Large cell neuroendocrine carcinoma | Oncology | Cancer Research | Internal Medicine | Argininosuccinate synthetase (ASS) | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Hydrolases - therapeutic use | Lung Neoplasms - enzymology | Humans | Middle Aged | Carcinoma, Neuroendocrine - therapy | Lung Neoplasms - pathology | Male | Lung Neoplasms - therapy | Polyethylene Glycols - therapeutic use | Patient Selection | Small Cell Lung Carcinoma - metabolism | Small Cell Lung Carcinoma - pathology | Neoplasm Grading | Carcinoma, Neuroendocrine - pathology | Argininosuccinate Synthase - deficiency | Aged, 80 and over | Carcinoma, Neuroendocrine - enzymology | Female | Aged | Small Cell Lung Carcinoma - therapy | Small Cell Lung Carcinoma - epidemiology | Molecular Targeted Therapy - methods | Precision Medicine - methods | Monoclonal antibodies | Carcinoma | Ligases | Lung cancer | Formaldehyde | Cancer | Index Medicus
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14. Full Text A collagen-remodeling gene signature regulated by TGF-β signaling is associated with metastasis and poor survival in serous ovarian cancer
by Cheon, Dong-Joo and Tong, Yunguang and Sim, Myung-Shin and Dering, Judy and Berel, Dror and Cui, Xiaojiang and Lester, Jenny and Beach, Jessica A and Tighiouart, Mourad and Walts, Ann E and Karlan, Beth Y and Orsulic, Sandra
Clinical cancer research, ISSN 1078-0432, 2014, Volume 20, Issue 3, pp. 711 - 723
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Pharmacology. Drug treatments | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Antineoplastic agents | Tumors | Female genital diseases | Immunohistochemistry | Oligonucleotide Array Sequence Analysis | Humans | Ovarian Neoplasms - pathology | Transcriptome | Cystadenocarcinoma, Serous - genetics | Ovarian Neoplasms - mortality | Cystadenocarcinoma, Serous - pathology | Ovarian Neoplasms - genetics | Heterografts | In Situ Hybridization | Neoplasm Invasiveness - pathology | Female | Collagen - genetics | Real-Time Polymerase Chain Reaction | Gene Expression Regulation, Neoplastic - genetics | Signal Transduction | Kaplan-Meier Estimate | Collagen - metabolism | Animals | Transforming Growth Factor beta - genetics | Cystadenocarcinoma, Serous - mortality | Mice | Neoplasm Invasiveness - genetics | Transforming Growth Factor beta - metabolism | Index Medicus | serous ovarian cancer | collagen | microarray | TGF-beta | gene signature | stroma