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Journal of Biological Chemistry, ISSN 0021-9258, 07/2003, Volume 278, Issue 28, pp. 25517 - 25525
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 27, pp. 12228 - 12232
The sterol regulatory element binding protein 2 (SREBP-2) and the liver X receptor (LXR) control antagonistic transcriptional programs that stimulate cellular... 
MicroRNA | Messenger RNA | HEK293 cells | Sterols | Adenoviruses | HDL lipoproteins | Mice | Repression | Macrophages | Cholesterols | ABCA1 | miRNA | High-density lipoprotein | ABCG1 | Cholesterol | high-density lipoprotein | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | MICRORNAS | STATINS | HIGH-DENSITY-LIPOPROTEIN | METABOLISM | CHOLESTEROL EFFLUX | cholesterol | MICE | BINDING | Cholesterol - blood | Humans | Transcriptional Activation | Molecular Sequence Data | Male | 5' Untranslated Regions - genetics | RNA, Messenger - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Base Sequence | ATP-Binding Cassette Transporters - metabolism | Lipoproteins, LDL - metabolism | Response Elements - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | ATP Binding Cassette Transporter 1 | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Cell Line | Receptors, LDL - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Gene Expression Regulation | Receptors, LDL - metabolism | Cholesterol - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Animals | Cholesterol, HDL - blood | MicroRNAs - genetics | Lipoproteins, LDL - blood | High density lipoproteins | Research | Properties | Binding proteins | Genetic regulation | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 11/2016, Volume 539, Issue 7628, pp. 294 - 298
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2009, Volume 4, Issue 9, p. e6951
Journal Article
The Lancet, ISSN 0140-6736, 10/2017, Volume 390, Issue 10104, pp. 1758 - 1768
Niemann-Pick disease, type C1 (NPC1) is a lysosomal storage disorder characterised by progressive neurodegeneration. In preclinical testing,... 
MIGLUSTAT THERAPY | STORAGE | MEDICINE, GENERAL & INTERNAL | HEPATOCELLULAR-CARCINOMA | CHOLESTEROL | BIOMARKER | CYCLODEXTRIN | CALBINDIN-D | PATIENT | BRAIN | CHILDREN | Injections, Spinal | Niemann-Pick Disease, Type C - drug therapy | 2-Hydroxypropyl-beta-cyclodextrin - adverse effects | Humans | Rare Diseases - drug therapy | Hearing Loss, High-Frequency - chemically induced | Child, Preschool | Niemann-Pick Disease, Type C - cerebrospinal fluid | Fatty Acid Binding Protein 3 - cerebrospinal fluid | Male | Biomarkers - blood | Hydroxycholesterols - cerebrospinal fluid | 2-Hydroxypropyl-beta-cyclodextrin - administration & dosage | Disease Progression | Dose-Response Relationship, Drug | Young Adult | Adolescent | Calbindins - cerebrospinal fluid | Female | Hydroxycholesterols - blood | Biomarkers - cerebrospinal fluid | Niemann-Pick Disease, Type C - blood | Child | Niemann-Pick disease | Medical research | Genetic disorders | Research & development--R&D | Clinical trials | Patients | Evidence-based medicine | Cholesterol | Studies | Cyclodextrin | Neurodegeneration | Biomarkers | Drug therapy | Drug dosages | Cerebellum | Regulatory agencies | Animal models | Childrens health | Hepatocellular carcinoma | Cognition | Cyclodextrins | Cerebrospinal fluid | Dosage | Proteins | Randomization | Npc1 protein | Bioindicators | Safety | Age | Health | FDA approval | Health care facilities | Hearing loss | Domains | Life span | Hearing aids | Mastoiditis | Ototoxicity
Journal Article
Journal Article
Scientific reports, ISSN 2045-2322, 04/2018, Volume 8, Issue 1, pp. 6361 - 2
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. 
Mass spectroscopy | Fourier transforms
Journal Article
Cell Metabolism, ISSN 1550-4131, 04/2013, Volume 17, Issue 4, pp. 549 - 561
Journal Article
Cell Reports, ISSN 2211-1247, 05/2019, Volume 27, Issue 9, pp. 2636 - 2648.e4
There is increasing evidence that the lysosome is involved in the pathogenesis of a variety of neurodegenerative disorders. Thus, mechanisms that link lysosome... 
Journal Article