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1. Full Text Mental Disorders Across the Adult Life Course and Future Coronary Heart Disease: Evidence for General Susceptibility
by Gale, Catharine R and Batty, G David and Osborn, David P J and Tynelius, Per and Rasmussen, Finn
Circulation, ISSN 0009-7322, 01/2014, Volume 129, Issue 2, pp. 186 - 193
BACKGROUND—Depression, anxiety, and psychotic disorders have been associated with an increased risk of coronary heart disease (CHD). It is unclear whether this... 
cohort studies | epidemiology | heart diseases | men | mental disorders | DEPRESSION | D PERSONALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | MIDDLE-AGE | CARDIAC MORTALITY | ILLNESS | RELATIVE RISK | ALL-CAUSE MORTALITY | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | PSYCHIATRIC-HOSPITAL ADMISSIONS | Body Mass Index | Smoking - adverse effects | Disease Susceptibility - psychology | Follow-Up Studies | Humans | Risk Factors | Proportional Hazards Models | Coronary Disease - epidemiology | Male | Mental Disorders - complications | Educational Status | Mental Health | Sweden - epidemiology | Alcohol Drinking - adverse effects | Coronary Disease - psychology | Social Class | Mental Disorders - psychology | Young Adult | Disease Susceptibility - epidemiology | Adolescent | Adult | Registries | Retrospective Studies | Longitudinal Studies | Complications and side effects | Research | Mental illness | Coronary heart disease | Risk factors
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2. Full Text Diagnosed depression and sociodemographic factors as predictors of mortality in patients with dementia
by Lewis, Gemma and Werbeloff, Nomi and Hayes, Joseph F and Howard, Robert and Osborn, David P. J
British Journal of Psychiatry, ISSN 0007-1250, 08/2018, Volume 213, Issue 2, pp. 471 - 476
Background Potentially modifiable risk factors for developing dementia have been identified. However, risk factors for increased mortality in patients with... 
SURVIVAL | EXCESS MORTALITY | PRIMARY-CARE | PSYCHIATRY | FOLLOW-UP | SYMPTOMS | MARITAL-STATUS | Sociodemographic aspects | Health records | Prognosis | Mental disorders | Health services | Cognitive ability | Mental health | National health services | Mental depression | Computerized medical records | Medical diagnosis | Electronic medical records | Risk factors | Mental health care | Databases | Dementia disorders | Codes | Unmet needs | Comorbidity | Mortality | Cultural differences | Minority & ethnic groups | Studies | Cohort analysis | Ethnicity | Asian Americans | Alzheimers disease | Electronic health records | Psychiatry | Dementia | Sociodemographics | Paper
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3. Full Text Self-harm, Unintentional Injury, and Suicide in Bipolar Disorder During Maintenance Mood Stabilizer Treatment: A UK Population-Based Electronic Health Records Study
by Hayes, Joseph F and Pitman, Alexandra and Marston, Louise and Walters, Kate and Geddes, John R and King, Michael and Osborn, David P. J
JAMA Psychiatry, ISSN 2168-622X, 06/2016, Volume 73, Issue 6, pp. 630 - 637
IMPORTANCE: Self-harm is a prominent cause of morbidity in patients with bipolar disorder and is strongly associated with suicide. There is evolving evidence... 
MORTALITY | TERM LITHIUM TREATMENT | PRIMARY-CARE | METAANALYSIS | ANTIPSYCHOTICS | PROPENSITY SCORE | PSYCHIATRY | BEHAVIOR | RISK | ANTIEPILEPTIC DRUGS | PHARMACOTHERAPY | Humans | Middle Aged | Male | Wounds and Injuries - epidemiology | Self-Injurious Behavior - epidemiology | Adult | Female | Valproic Acid - therapeutic use | Valproic Acid - adverse effects | Antimanic Agents - adverse effects | Quetiapine Fumarate - adverse effects | Antimanic Agents - therapeutic use | Cross-Sectional Studies | Treatment Outcome | United Kingdom | Bipolar Disorder - drug therapy | Suicide - statistics & numerical data | Quetiapine Fumarate - therapeutic use | Lithium Carbonate - therapeutic use | Propensity Score | Benzodiazepines - adverse effects | Benzodiazepines - therapeutic use | Electronic Health Records | Lithium Carbonate - adverse effects | Longitudinal Studies | Bipolar Disorder - epidemiology | Cohort Studies
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4. Full Text Mortality gap for people with bipolar disorder and schizophrenia: UK-based cohort study 2000-2014
by Hayes, Joseph F and Marston, Louise and Walters, Kate and King, Michael B and Osborn, David P. J
British Journal of Psychiatry, ISSN 0007-1250, 09/2017, Volume 211, Issue 3, pp. 175 - 181
Background Bipolar disorder and schizophrenia are associated with increased mortality relative to the general population. There is an international emphasis on... 
SEVERE MENTAL-DISORDERS | PREMATURE MORTALITY | EXCESS MORTALITY | PRIMARY-CARE | IMPROVEMENT NETWORK THIN | PSYCHIATRY | RISK | HEALTH | SELF-HARM | CARDIOVASCULAR MORBIDITY | PRACTICE RESEARCH DATABASE | Health records | Cohort analysis | Mental disorders | Mortality | Suicides & suicide attempts | Schizophrenia | Bipolar disorder | Computerized medical records | Primary care | Electronic medical records | Papers
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5. Full Text Risks and benefits of psychotropic medication in pregnancy: Cohort studies based on UK electronic primary care health records
by Petersen, Irene and McCrea, Rachel L and Sammon, Cormac J and Osborn, David P. J and Evans, Stephen J and Cowen, Phillip J and Freemantle, Nick and Nazareth, Irwin
Health Technology Assessment, ISSN 1366-5278, 03/2016, Volume 20, Issue 23, pp. 1 - 208
Background: Although many women treated with psychotropic medication become pregnant, no psychotropic medication has been licensed for use in pregnancy. This... 
ATYPICAL ANTIPSYCHOTIC-DRUGS | RANDOMIZED-TRIALS | IN-UTERO EXPOSURE | ANTIDEPRESSANT THERAPY | HEALTH CARE SCIENCES & SERVICES | POPULATION-BASED COHORT | SPECTRUM DISORDERS | OF-THE-LITERATURE | ANTIEPILEPTIC DRUGS | BIPOLAR DISORDER | POSTPARTUM PERIOD | Risk Assessment | Antipsychotic Agents - adverse effects | Humans | United Kingdom | Psychotic Disorders - epidemiology | Drug Utilization | Pregnancy Complications - drug therapy | Pregnancy | Young Adult | Antipsychotic Agents - therapeutic use | Adult | Female | Primary Health Care | Psychotic Disorders - drug therapy | Retrospective Studies | Valproic Acid - adverse effects | Electronic Health Records | Infant, Newborn | Pregnancy Complications - epidemiology
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6. Full Text Cross-cultural attitudes to help-seeking among individuals whoare suicidal: new perspective for policy-makers
by Pitman Alexandra and Osborn David P J
The British Journal of Psychiatry, ISSN 0007-1250, 07/2011, Volume 199, Issue 1, pp. 8 - 10
World Mental Health Survey data demonstrate that a high proportion of peoplewho are suicidal receive no treatment and that, contrary to previousassumptions,... 
Low income groups | Health sciences | High income | Mental disorders | Stigma | Mental health | Attitudes | Perceptions | Systematic review | Suicide | Epidemiology | Stigmatization | Self destructive behavior | Cultural attitudes | Prevention | Policy making | Mental health care | Suicides & suicide attempts | Patient satisfaction | Helpseeking | Psychiatry | Health surveys | Public health
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7. Full Text Adverse Renal, Endocrine, Hepatic, and Metabolic Events during Maintenance Mood Stabilizer Treatment for Bipolar Disorder: A Population-Based Cohort Study
by Hayes, Joseph F and Marston, Louise and Walters, Kate and Geddes, John R and King, Michael and Osborn, David P. J
PLoS Medicine, ISSN 1549-1277, 08/2016, Volume 13, Issue 8, p. e1002058
Background There is limited, poorly characterized information about adverse events occurring during maintenance treatment of bipolar disorder. We aimed to... 
GLOMERULAR-FILTRATION-RATE | MEDICINE, GENERAL & INTERNAL | PRIMARY-CARE | MANAGEMENT | METAANALYSIS | PROPENSITY SCORE METHODS | BIAS | DATABASES | MODEL | CHRONIC KIDNEY-DISEASE | LITHIUM | Antipsychotic Agents - adverse effects | Humans | Middle Aged | Male | Renal Insufficiency - chemically induced | Antipsychotic Agents - therapeutic use | Hypertension - chemically induced | Adult | Female | Valproic Acid - therapeutic use | Thyroid Diseases - chemically induced | Valproic Acid - adverse effects | Chemical and Drug Induced Liver Injury - etiology | Quetiapine Fumarate - adverse effects | Hypercalcemia - chemically induced | Lithium Compounds - adverse effects | Bipolar Disorder - drug therapy | Quetiapine Fumarate - therapeutic use | Propensity Score | Lithium Compounds - therapeutic use | Benzodiazepines - adverse effects | Cardiovascular Diseases - chemically induced | Diabetes Mellitus, Type 2 - chemically induced | Benzodiazepines - therapeutic use | Longitudinal Studies | Cohort Studies | Type 2 diabetes | Complications and side effects | Chronic kidney failure | Antidepressants | Primary health care | Analysis | Family medicine | Bipolar disorder | Dosage and administration | Management | Drug therapy | Hypertension | Substance abuse treatment | Thyroid diseases | Cardiovascular disease | Metabolism | Primary care | Patients | Studies | Confidence intervals | Collaboration | Physiology | Diabetes | Kidney diseases
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8. Full Text The stigma perceived by people bereaved by suicide and other sudden deaths: A cross-sectional UK study of 3432 bereaved adults
by Pitman, Alexandra L and Osborn, David P.J and Rantell, Khadija and King, Michael B
Journal of Psychosomatic Research, ISSN 0022-3999, 08/2016, Volume 87, pp. 22 - 29
To test the hypothesis that perceived stigma scores in young adults bereaved by suicide are significantly higher than in young adults bereaved by other sudden... 
Bereavement | Guilt | Suicide | Responsibility | Stigma | Shame | PSYCHIATRY | NEEDS | MENTAL-HEALTH | SCALE | SURVIVORS | Death, Sudden - epidemiology | Grief | Cross-Sectional Studies | Humans | Male | Young Adult | Adolescent | Suicide - psychology | Adult | Family | Female | Perception | Surveys and Questionnaires | Social Stigma | United Kingdom - epidemiology | Adults
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9. Full Text Prescribing of antipsychotics in UK primary care: a cohort study
by Marston, Louise and Nazareth, Irwin and Petersen, Irene and Walters, Kate and Osborn, David P J
BMJ Open, ISSN 2044-6055, 12/2014, Volume 4, Issue 12, p. e006135
Objective To examine the recorded indication for antipsychotic prescriptions in UK primary care. Design Cohort study. Setting Primary care. Participants... 
MEDICINE, GENERAL & INTERNAL | BRITISH-ASSOCIATION | DISORDERS | RISK | PERIODS | TRENDS | Mood Disorders - drug therapy | Humans | Middle Aged | Male | Young Adult | Practice Patterns, Physicians' - statistics & numerical data | Risperidone - therapeutic use | Antipsychotic Agents - therapeutic use | Aged, 80 and over | Adult | Female | Child | Severity of Illness Index | Inappropriate Prescribing | Dementia - drug therapy | United Kingdom | Bipolar Disorder - drug therapy | Drug Prescriptions - statistics & numerical data | Mental Disorders - drug therapy | Adolescent | Aged | Primary Health Care | Psychotic Disorders - drug therapy | Schizophrenia - drug therapy | Cohort Studies
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10. Full Text Association of Hydroxylmethyl Glutaryl Coenzyme A Reductase Inhibitors, L-Type Calcium Channel Antagonists, and Biguanides with Rates of Psychiatric Hospitalization and Self-Harm in Individuals with Serious Mental Illness
by Hayes, Joseph F and Lundin, Andreas and Wicks, Susanne and Lewis, Glyn and Wong, Ian C. K and Osborn, David P. J and Dalman, Christina
JAMA Psychiatry, ISSN 2168-622X, 2018, Volume 76, Issue 4, pp. 382 - 390
IMPORTANCE Drug repurposing is potentially cost-effective, low risk, and necessary in psychiatric drug development. The availability of large, routine data... 
METFORMIN | REGISTER | MANAGEMENT | PSYCHIATRY | DISEASE | SCHIZOPHRENIA | WEIGHT-GAIN | OPPORTUNITIES | SIMVASTATIN | STATINS | CARDIOVASCULAR RISK | Online First | Original Investigation | Research
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11. Full Text Cardiovascular Risk Prediction Models for People With Severe Mental Illness: Results From the Prediction and Management of Cardiovascular Risk in People With Severe Mental Illnesses (PRIMROSE) Research Program
by Osborn, David P. J and Hardoon, Sarah and Omar, Rumana Z and Holt, Richard I. G and King, Michael and Larsen, John and Marston, Louise and Morris, Richard W and Nazareth, Irwin and Walters, Kate and Petersen, Irene
JAMA Psychiatry, ISSN 2168-622X, 02/2015, Volume 72, Issue 2, pp. 143 - 151
IMPORTANCE: People with severe mental illness (SMI), including schizophrenia and bipolar disorder, have excess rates of cardiovascular disease (CVD). Risk... 
MORTALITY | METABOLIC SYNDROME | PRIMARY-CARE | EVENTS | PSYCHIATRY | SCHIZOPHRENIA | RELATIVE RISK | Prognosis | Comorbidity | Humans | Middle Aged | Male | Risk | Models, Statistical | Psychotic Disorders - epidemiology | Schizophrenia - epidemiology | Electronic Health Records - statistics & numerical data | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Adult | Female | Aged | United Kingdom - epidemiology | Bipolar Disorder - epidemiology | Cardiovascular Diseases - diagnosis | Complications and side effects | Cardiovascular diseases | Mental illness | Health aspects | Risk factors | Mentally ill
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12. Full Text Recording of severe mental illness in United Kingdom primary care, 2000-2010
by Hardoon, Sarah and Hayes, Joseph F and Blackburn, Ruth and Petersen, Irene and Walters, Kate and Nazareth, Irwin and Osborn, David P. J
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e82365
Background: There is increasing emphasis on primary care services for individuals with severe mental illnesses (SMI), including schizophrenia, bipolar... 
INCIDENCE RATES | GENERAL-POPULATION | LIFETIME PREVALENCE | NONAFFECTIVE PSYCHOSIS | STABILITY | MULTIDISCIPLINARY SCIENCES | NATIONAL-COMORBIDITY-SURVEY | BIPOLAR I DISORDER | SCHIZOPHRENIA | GENDER-DIFFERENCES | EPIDEMIOLOGY | Demography | Mental Disorders - epidemiology | Primary Health Care - statistics & numerical data | Humans | Middle Aged | Male | Bipolar Disorder - diagnosis | Schizophrenia - epidemiology | Young Adult | Schizophrenia - diagnosis | Time Factors | Adolescent | General Practice | Aged, 80 and over | Adult | Female | Aged | United Kingdom - epidemiology | Bipolar Disorder - epidemiology | Databases, Factual | Medicine | Schizophrenia | Medical records | Practice | Family medicine | Bipolar disorder | Health aspects | Epidemiology | Mentally ill | Health care | Deprivation | Mental disorders | Computer programs | Psychosis | Studies | Demographics | Databases | Illnesses | Recording | Diagnosis | Age
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