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Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 2005, Volume 20, Issue 5, pp. 309 - 323
The binding of drugs to plasma proteins, such as albumin and α1-acid glycoprotein (AGP) is a major determinant in the disposition of drugs. A topology analysis... 
molecular aspect | interaction | α1-acid glycoprotein | protein binding | albumin | Pharmaceutical Preparations - metabolism | Drug Interactions | Biological Transport | Uremia - blood | Humans | Orosomucoid - chemistry | Orosomucoid - metabolism | Protein Binding | Serum Albumin - chemistry | Binding Sites | Serum Albumin - metabolism
Journal Article
Drug Delivery System, ISSN 0913-5006, 04/2016, Volume 31, Issue 1, pp. 8 - 8
Journal Article
Cancer Science, ISSN 1347-9032, 03/2015, Volume 106, Issue 3, pp. 270 - 278
Previously, we prepared a pirarubicin (THP)‐encapsulated micellar drug using styrene–maleic acid copolymer (SMA) as the drug carrier, in which active THP was... 
Antimetastatic property | prolonged plasma half‐life | SMA‐THP conjugate | antitumor effect | enhanced permeability and retention effect | Prolonged plasma half-life | Antitumor effect | Enhanced permeability and retention effect | SMA-THP conjugate | CELLS | AGENT SMANCS | DRUG-DELIVERY | DOXORUBICIN | MICELLES | NEOCARZINOSTATIN | LIVER METASTASES | NANOPARTICLES | IN-VITRO | ONCOLOGY | ADRIAMYCIN | prolonged plasma half-life | Drug Carriers - adverse effects | Lung Neoplasms - drug therapy | Maleates - pharmacology | Humans | Polystyrenes - pharmacology | Male | Maleates - adverse effects | Mitochondrial Proteins | Maleates - chemical synthesis | Polystyrenes - chemical synthesis | Lung Neoplasms - secondary | Antineoplastic Agents - adverse effects | Micelles | Doxorubicin - analogs & derivatives | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Rats | Drug Carriers - chemical synthesis | Rats, Sprague-Dawley | Doxorubicin - pharmacokinetics | Drug Carriers - pharmacology | Polystyrenes - adverse effects | Animals | Cell Line, Tumor | Mice | Mice, Inbred BALB C | HeLa Cells | Doxorubicin - adverse effects | Doxorubicin - pharmacology | Permeability | Health aspects | Lung cancer | Analysis | Drugs | Laboratories | Cytotoxicity | Metastasis | Cancer therapies | Chromatography | Metastases | Acids | Blood circulation | Spectrum analysis | Maleic acid | Styrene | Antitumor activity | Polymers | Nanotechnology | Tumors | Index Medicus | Original
Journal Article
Current medicinal chemistry, 11/2018
Carbon monoxide (CO), at low concentrations, can have a variety of positive effects on the body including anti-apoptosis, anti-inflammatory, anti-oxidative and... 
Journal Article
BBA - General Subjects, ISSN 0304-4165, 12/2013, Volume 1830, Issue 12, pp. 5435 - 5443
Journal Article
Yakugaku Zasshi, ISSN 0031-6903, 04/2009, Volume 129, Issue 4, pp. 413 - 425
Journal Article
Kidney International, ISSN 0085-2538, 04/2013, Volume 83, Issue 4, pp. 582 - 592
The accumulation of -cresyl sulfate (PCS), a uremic toxin, is associated with the mortality rate of chronic kidney disease patients; however, the biological... 
p-cresyl sulfate | chronic kidney disease | uremic toxins | indoxyl sulfate | NADPH oxidase | oxidative stress | KAPPA-B | ORGANIC ANION TRANSPORTERS | FAILURE | CRESYLSULPHATE | ENDOTHELIAL-CELLS | UROLOGY & NEPHROLOGY | SMOOTH-MUSCLE-CELLS | CHRONIC KIDNEY-DISEASE | EXPRESSION | Cresols - toxicity | Reactive Oxygen Species - metabolism | Epithelial Cells - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | NADPH Oxidases - metabolism | Male | Sulfuric Acid Esters - toxicity | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Transfection | Nephrectomy | RNA Interference | Inflammation Mediators - metabolism | Renal Insufficiency, Chronic - genetics | NADPH Oxidases - genetics | Kidney Tubules, Proximal - enzymology | Cytokines - genetics | Cell Line | Cell Survival - drug effects | Kidney Tubules, Proximal - pathology | Collagen Type I - metabolism | Cytokines - metabolism | Probenecid - pharmacology | Rats | Epithelial Cells - pathology | NADPH Oxidase 4 | Renal Insufficiency, Chronic - enzymology | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - pathology | Animals | Epithelial Cells - enzymology | Fibrosis | Enzyme Activation | Oxidative Stress - drug effects | Renal Insufficiency, Chronic - chemically induced | Kidney Tubules, Proximal - drug effects | Index Medicus
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2018, Volume 66, Issue 4, pp. 382 - 390
Journal Article
Cancer Science, ISSN 1347-9032, 02/2015, Volume 106, Issue 2, pp. 194 - 200
Journal Article