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2017, Methods in molecular biology, ISBN 1493964399, Volume 1491.
This volume focuses on explorative activity-based proteomics, biomedical applications of activity-based proteomics, and chemical strategies in activity-based... 
Proteogenomics | methods | Proteomics | Structure-Activity Relationship
Web Resource
2017, Methods in molecular biology, ISBN 1493964399, Volume 1491.
This volume focuses on explorative activity-based proteomics, biomedical applications of activity-based proteomics, and chemical strategies in activity-based... 
Proteogenomics | methods | Structure-Activity Relationship
Web Resource
Molecular & Biochemical Parasitology, ISSN 0166-6851, 01/2019, Volume 227, pp. 1 - 4
Previous studies indicated that the proteasome of the protozoan parasite is particularly sensitive to inhibition of the trypsin-like activity. In this study,... 
Trypanosoma brucei | African trypanosomiasis | Proteasome | β2 subunit-specific inhibitors | Index Medicus
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 03/2019, Volume 2019, Issue 10, p. 1994
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2018, Volume 175, Issue 1, pp. 38 - 52
Journal Article
2017, Methods in Molecular Biology, ISBN 9781493964376, Volume 1491
eBook
ISSN 1359-7345, 9/2017, Volume 53, Issue 74, pp. 1255 - 1258
Poly-adenosine diphosphate ribose (PAR) is a branched biopolymer that occurs as a result of post-translational modification of proteins. In 1981 Miwa et al.... 
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2019, Volume 14, Issue 7, pp. e0212382 - e0212382
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1491, pp. 103 - 111
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 12/2016, Volume 35, Issue 23, pp. 2602 - 2613
Inhibition of the immunoproteasome subunit 5i alleviates autoimmune diseases in preclinical studies and represents a promising new anti-inflammatory therapy.... 
immunoproteasome | COMPLEX | mode of action | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BORTEZOMIB | LMP7 | ligand | CELL BIOLOGY | X-ray crystallography | 20S PROTEASOME | SUBSTRATE-SPECIFICITY | SELECTIVE INHIBITORS | species selectivity | Yeast | Autoimmune diseases | Proteases | Crystallography
Journal Article
Science, ISSN 0036-8075, 06/2017, Volume 356, Issue 6342, pp. 1084 - 1087
A recent phase 1 trial of the fatty acid amide hydrolase (FAAH) inhibitor BIA 10-2474 led to the death of one volunteer and produced mild-to-severe... 
MOLECULAR CHARACTERIZATION | ENZYME | PAIN | ACID AMIDE HYDROLASE-1 | CLINICAL-TRIAL | MULTIDISCIPLINARY SCIENCES | ANANDAMIDE | RECEPTOR | BLOCKADE | ESTERASE | PF-04457845 | Anti-Anxiety Agents - metabolism | Analgesics - pharmacology | Pyridines - chemistry | Humans | Analgesics - metabolism | Pyridazines - pharmacology | Protein Interaction Maps | Pyridines - adverse effects | Cyclic N-Oxides - adverse effects | Cyclic N-Oxides - pharmacology | Urea - analogs & derivatives | Cyclic N-Oxides - metabolism | Anti-Anxiety Agents - adverse effects | Anti-Anxiety Agents - chemistry | Neurons - metabolism | Neurons - drug effects | Pyridazines - therapeutic use | Analgesics - adverse effects | Anti-Anxiety Agents - pharmacology | Amidohydrolases - antagonists & inhibitors | Cross Reactions | Cyclic N-Oxides - chemistry | Urea - therapeutic use | Pyridines - metabolism | Analgesics - chemistry | Cell Line, Tumor | Pyridines - pharmacology | Clinical Trials, Phase I as Topic | Urea - pharmacology | Amino acid sequence | Methods | Fatty-acid amide hydrolase | Brain | Profiling | Hydrolase | Neurons | Therapeutic applications | Cortex | Nervous system | Tissue analysis | Metabolism | Lipase | Tissues | Fatty acids | Proteins | Neurotoxicity | Pain | Inhibitors | Brain damage | Anxiety | Lipid metabolism | Brain injury | Index Medicus | Drugs | Networks | Proteomics | Amides
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 1, pp. 26 - 33
Journal Article
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