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Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2105 - 2105
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 07/2015, Volume 11, Issue 8, pp. 536 - 541
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12853 - 12858
SET domain containing (lysine methyltransferase) 7 (SETD7) is implicated in multiple signaling and disease related pathways with a broad diversity of reported... 
Enzymes | Transcriptional regulatory elements | Genes | Cell lines | Histones | Gene expression regulation | Kinetics | Methylation | Inhibitory concentration 50 | Chemicals | Chemical biology | Epigenetics | Chemical probe | METHYLATION | STABILITY | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | SET7/9 | epigenetics | LYSINE METHYLTRANSFERASE | ENZYME | chemical biology | PATHWAY | PURIFICATION | GENES | chemical probe | Humans | Methyltransferases - metabolism | Structure-Activity Relationship | Phosphoproteins - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | MCF-7 Cells | Tetrahydroisoquinolines - chemistry | Enzyme Inhibitors - chemistry | Epigenesis, Genetic - drug effects | Protein Structure, Tertiary | Tetrahydroisoquinolines - pharmacology | Histone-Lysine N-Methyltransferase - genetics | Sulfonamides - chemistry | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Phosphoproteins - genetics | Sulfonamides - pharmacology | Pyrrolidines - chemistry | Methyltransferases - antagonists & inhibitors | Histone-Lysine N-Methyltransferase - metabolism | Signal Transduction - drug effects | Fibroblasts - drug effects | Adaptor Proteins, Signal Transducing - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Protein research | Research | Methyltransferases | Lysine | Health aspects | Protein-protein interactions | Biological Sciences
Journal Article
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3865 - 3878
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 04/2016, Volume 37, Issue 1, pp. 47 - 57
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2009, Volume 19, Issue 15, pp. 4406 - 4409
We have identified a new class of selective, potent CB2 agonists. The drug-like properties of this series is discussed in terms of Lipophilic Efficiency... 
CB2 | Agonist | Parallel synthesis | LiPE | Lipophilicity | CHEMISTRY, MEDICINAL | CHEMISTRY, ORGANIC | CANNABINOID RECEPTOR AGONISTS
Journal Article
Journal Article
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 08/2009, Volume 19, Issue 15, pp. 4406 - 4409
A series of libraries were designed using the 1-(cyclopropylmethyl)-2-alkyl-4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridin-5-ium templates 2a- b, and Sulfonamide... 
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2016, Volume 59, Issue 10, pp. 4800 - 4811
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 09/2019, Volume 62, Issue 17, pp. 7669 - 7683
The first chemical probe to primarily occupy the co-factor binding site of a Su(var)3-9, enhancer of a zeste, trithorax (SET) domain containing protein lysine... 
POTENT | METHYLATION | CHEMISTRY, MEDICINAL | DISCOVERY | Index Medicus
Journal Article