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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 967 - 15
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2018, Volume 38, Issue Suppl_1
Journal Article
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 05/2019, Volume 33, Issue 3, pp. 1500 - 1506
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2019, Volume 39, Issue 5, pp. 836 - 838
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A17184 - A17184
Atherosclerosis is a disease of chronic inflammation and the leading cause of morbidity and mortality worldwide. Despite decades of research, our understanding... 
Journal Article
Circulation Research, ISSN 0009-7330, 04/2019, Volume 124, Issue 9, pp. 1297 - 1299
Thromboembolic events secondary to rupture or erosion of advanced atherosclerotic plaques represent the leading cause of death worldwide. However, the... 
atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | genetics | smooth muscle | PERIPHERAL VASCULAR DISEASE | animals | HEMATOLOGY | humans | mice
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2009, Volume 296, Issue 4, pp. H1027 - H1037
Journal Article
The Journal of cell biology, 04/2015, Volume 209, Issue 1, p. 13
Atherosclerosis occurs in the subendothelial space (intima) of medium-sized arteries at regions of disturbed blood flow and is triggered by an interplay... 
Macrophages - physiology | Mechanotransduction, Cellular | Atherosclerosis - pathology | Muscle, Smooth, Vascular - pathology | Animals | Atherosclerosis - immunology | Humans | Myocytes, Smooth Muscle - physiology | Endothelium, Vascular - pathology | Endothelial Cells - physiology
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 12/2015, Volume 35, Issue 12, pp. 2508 - 2516
Vascular smooth muscle cells (SMC), like all cells, acquire a cell-specific epigenetic signature during development that includes acquisition of a unique... 
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Many studies have noted similarities between atherosclerosis and cancer including pronounced cellular plasticity, clonal expansion of cellular subtypes,... 
atherosclerosis | macrophages | efferocytosis | smooth muscle | oncogenes | neoplasms | myocytes
Journal Article
Circulation Research, ISSN 0009-7330, 06/2008, Volume 102, Issue 12, pp. 1548 - 1557
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 11/2008, Volume 295, Issue 5, pp. 1175 - 1182
Phenotypic switching of vascular smooth muscle cells (SMCs), such as increased proliferation, enhanced migration, and downregulation of SMC differentiation... 
Extracellular signal-regulated kinases 1/2 | Histone acetylation | Gene transcription | ALPHA-ACTIN | MYOCARDIN | gene transcription | ACTIVATION | PHYSIOLOGY | TRANSCRIPTION | LOW-DENSITY-LIPOPROTEIN | extracellular signal-regulated kinases 1/2 | CELL BIOLOGY | REPRESSION | IN-VIVO | GENE-EXPRESSION | VASCULAR ENDOTHELIAL-CELLS | PROMOTER | histone acetylation | Phosphorylation | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Actins - metabolism | Cercopithecus aethiops | ets-Domain Protein Elk-1 - genetics | Actins - genetics | Cell Differentiation - genetics | Transfection | Time Factors | Kruppel-Like Transcription Factors - metabolism | ets-Domain Protein Elk-1 - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Repressor Proteins - metabolism | Promoter Regions, Genetic | Phospholipid Ethers - metabolism | Histone Deacetylases - genetics | Down-Regulation | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Rats | Repressor Proteins - genetics | Histone Deacetylase 2 | Histone Deacetylases - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Cell Differentiation - drug effects | Protein Binding | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | COS Cells | Kruppel-Like Transcription Factors - genetics | Mitogen-Activated Protein Kinase 1 - metabolism | Cell culture | Signal transduction | Lipids | Kinases | Genes | Cells | Index Medicus | extracellular signal-regulated kinases 1 | Vascular Biology
Journal Article
Journal Article
CIRCULATION RESEARCH, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 624 - 626
Many studies have noted similarities between atherosclerosis and cancer including pronounced cellular plasticity, clonal expansion of cellular subtypes,... 
PERIPHERAL VASCULAR DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 6, pp. 685 - 696
RATIONALE:We previously identified conserved G/C Repressor elements in the promoters of most smooth muscle cell (SMC) marker genes and demonstrated that... 
acetylation | smooth muscle cells | gene transcription | HDAC2 | vascular disease | transcription factors | pELK-1 | smooth muscle | KLF4 | INDUCED STIMULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | TGF-BETA | ALPHA-ACTIN EXPRESSION | DIFFERENTIATION MARKER GENES | SMOOTH-MUSCLE-CELL | VASCULAR INJURY | HISTONE DEACETYLASES | SERUM RESPONSE FACTOR | PERIPHERAL VASCULAR DISEASE | OXIDIZED PHOSPHOLIPIDS | HEMATOLOGY | GROWTH FACTOR-BB | Transcription, Genetic - drug effects | Muscle, Smooth, Vascular - metabolism | Humans | ets-Domain Protein Elk-1 - genetics | Promoter Regions, Genetic - genetics | Transfection | Chromatin Immunoprecipitation | RNA Interference | Kruppel-Like Transcription Factors - metabolism | ets-Domain Protein Elk-1 - metabolism | Protein Binding - drug effects | Carotid Artery Injuries - genetics | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Microfilament Proteins - genetics | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Histone Deacetylase 2 - genetics | Mice, Inbred C57BL | Cells, Cultured | Rats | Mice, Transgenic | Muscle, Smooth, Vascular - cytology | Regulatory Sequences, Nucleic Acid - genetics | Phospholipid Ethers - pharmacology | Gene Expression Regulation - drug effects | Muscle Proteins - genetics | Animals | Mice | Histone Deacetylase 2 - metabolism | Mutation | Kruppel-Like Transcription Factors - genetics | Index Medicus | Smooth muscle cells
Journal Article