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by Tabassum, R and Ramo, JT and Ripatti, P and Koskela, JT and Kurki, M and Karjalainen, J and Palta, P and Hassan, S and Nunez-Fontarnau, J and Kiiskinen, TTJ and Soderlund, S and Matikainen, N and Gerl, MJ and Surma, MA and Klose, C and Stitziel, NO and Laivuori, H and Havulinna, AS and Service, SK and Salomaa, V and Pirinen, M and Jauhiainen, M and Daly, MJ and Freimer, NB and Palotie, A and Taskinen, MR and Simons, K and Ripatti, S and Jalanko, A and Kaprio, J and Donner, K and Kaunisto, M and Mars, N and Dada, A and Shcherban, A and Ganna, A and Lehisto, A and Kilpelainen, E and Brein, G and Awaisa, G and Harju, J and Parr, K and Parolo, PD and Kajanne, R and Lemmela, S and Sipila, TP and Sipila, T and Lyhs, U and Llorens, V and Niiranen, T and Kristiansson, K and Mannikko, L and Jimenez, MG and Perola, M and Wong, R and Kilpi, T and Hiekkalinna, T and Jarvensivu, E and Kaiharju, E and Mattsson, H and Laukkanen, M and Laiho, P and Lahteenmaki, S and Sistonen, T and Soini, S and Ziemann, A and Lehtonen, A and Lertratanakul, A and Georgantas, B and Riley-Gillis, B and Quarless, D and Rahimov, F and Heap, G and Jacob, H and Waring, J and Davis, JW and Smaoui, N and Popovic, R and Esmaeeli, S and Matakidou, A and Challis, B and Close, D and Petrovski, S and Karlsson, A and Schleutker, J and Pulkki, K and Virolainen, P and Kallio, L and Mannermaa, A and Heikkinen, S and Kosma, VM and Chen, CY and Runz, H and Liu, J and Bronson, P and John, S and Landenpera, S and Eaton, S and Zhou, W and Hendolin, M and ... and FinnGen Project
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 1 - 14
Understanding genetic architecture of plasma lipidome could provide better insights into lipid metabolism and its link to cardiovascular diseases (CVDs). Here,... 
INSULIN | PREDIMED TRIAL | HOSPITAL DISCHARGE REGISTER | RISK-FACTORS | RARE VARIANTS | GENOTYPE IMPUTATION | CERAMIDES | MULTIDISCIPLINARY SCIENCES | DEATH | VALIDITY | GENOME-WIDE ASSOCIATION | Phenotypes | Architecture | Lipids | Genomes | Lipoprotein lipase | Triglycerides | Lipase | Gene expression | Metabolism | Fatty acids | Loci | Blood plasma | Genetic variance | Heritability | Lipid metabolism | Cardiovascular diseases | Species
Journal Article
by Gormley, A.M and Stefansson, Hreinn and Winsvold, Bendik and Palta, Priit and Esko, Tõnu and Pers, Tune and Farh, Kai-How and Cuenca-Leon, E and Muona, M and Furlotte, N.A and Kurth, Karl and Ingason, Anes and Mcmahon, George and Ligthart, Lannie and Terwindt, Gisela and Todt, Unda and Müller-Myhsok, Bertram and Ran, C and Gordon, S.G and Stam, Anine and Steinberg, Stacy and Göbel, Hartmut and Koiranen, Markku and Quaye, Lydia and Adams, H.H.H and Lehtimäki, Terho and Sarin, A.-P and Wedenoja, J and Hinds, David A and Buring, J.E and Schürks, Markus and Ridker, Paul and Hrafnsdottir, M.G and Ring, Susan and Hottenga, Jouke Jan and Penninx, Brenda and Färkkilä, Markus and Artto, Ville and Hämäläinen, Eija and Lucae, Susanne and Malik, Rainer and Heath, Anew C and Madden, Pamela and Martin, Nicholas and Montgomery, Grant and Kurki, M.I and Kals, Mart and Mägi, Reedik and Pärn, K and Hamalainen, Eija and Huang, H and Byrnes, A.E and Franke, Lude and Huang, Jian and Stergiakouli, Evangelia and Lee, Phil and Sandor, C and Webber, C and Cader, Z and Müller-Myhsok, B and Schreiber, Stefan and Meitinger, Thomas and Hagen, Knut and Salomaa, Veikko and Heikkilä, Kauko and Loehrer, Elizabeth and Uitterlinden, Ané and Hofman, A and Duijn, Cornelia and Cherkas, Lynn and Pedersen, L.M and Stubhaug, A and Nielsen, C.S and Männikkö, M and Mihailov, Evelin and Milani, Lili and Esserlind, A.-L and Christensen, A.F and Hansen, T.F and Werge, Thomas and Kaprio, Jaakko and Aromaa, Arpo and Raitakari, Olli and Ikram, Arfan and Ikram, Kamran and Jarvelin, Marjo-Riitta and Metspalu, Anes and Kubisch, Christian and Strachan, David and Ferrari, Michel and Belin, A.C and Wessman, Maija and Maagdenberg, Arn and Zwart, John-Anker and Boomsma, Dorret and Smith, G.D and Stefansson, K and Eriksson, Nicholas and Daly, Mark and Neale, Benjamin and ... and Int Headache Genetics Consortium and International Headache Genetics Consortium
Nature Genetics, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 856 - 866
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1 - 8
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 07/2015, Volume 209, pp. 238 - 247
Gene therapy has great potential to treat a range of different diseases, such as cancer. For that therapeutic gene can be inserted into a plasmid vector and... 
Gene delivery | Tumor | Matrix metalloprotease | PEGylation | Non-covalent complexes | Cell-penetrating peptide | VITRO | DRUG-DELIVERY | CELL-PENETRATING PEPTIDES | MICELLES | POLYETHYLENIMINE | CHEMISTRY, MULTIDISCIPLINARY | VECTOR | DNA COMPLEXES | THERAPY | INJECTION | PHARMACOLOGY & PHARMACY | EXPRESSION | Neoplasms - metabolism | Luciferases - metabolism | Cricetulus | Nanoparticles - chemistry | Humans | Polyethylene Glycols - chemistry | Luciferases - genetics | Neoplasms - genetics | Lipopeptides - chemistry | Cell-Penetrating Peptides - chemistry | Genes, Reporter | CHO Cells | Cell Line | Gene Transfer Techniques | Cricetinae | Gene Expression | Matrix Metalloproteinase 2 - metabolism | DNA - administration & dosage | Polyethylene Glycols - administration & dosage | Neoplasms - drug therapy | DNA - chemistry | Animals | Tumor Burden - drug effects | Plasmids | Cell Line, Tumor | Mice | Cell-Penetrating Peptides - administration & dosage | Lipopeptides - administration & dosage | Neoplasms - pathology | Genetic vectors | Genes | Genetic research | Gene therapy | Gene expression | Health aspects | Polyols | Tumors | Anopheles | Peptides | Proteases | Polyethylene glycol | Permeability | Genetic translation | Cancer | Biological Sciences | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Chemical Sciences | Neurochemistry with Molecular Neurobiology | Naturvetenskap | Kemi | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | neurokemi med molekylär neurobiologi | Farmakologi och toxikologi | Natural Sciences | Pharmacology and Toxicology
Journal Article
Journal Article
Molecular Ecology, ISSN 0962-1083, 09/2018, Volume 27, Issue 17, pp. 3498 - 3514
Journal Article
Journal of Housing and the Built Environment, ISSN 1566-4910, 12/2019, Volume 34, Issue 4, pp. 1149 - 1167
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2017, Volume 114, Issue 3, pp. E327 - E336
Genetic variants affecting hematopoiesis can influence commonly measured blood cell traits. To identify factors that affect hematopoiesis, we performed... 
CEBPA | GWAS | Genome sequencing | Basophils | Hematopoiesis | FETAL-HEMOGLOBIN LEVELS | PARTITIONING HERITABILITY | COPY NUMBER VARIATIONS | MULTIDISCIPLINARY SCIENCES | LOCI | basophils | MAST-CELL | GENETIC-VARIATION | hematopoiesis | C/EBP-ALPHA | BASOPHIL | genome sequencing | WIDE ASSOCIATION | NONCODING VARIANTS | Index Medicus | Biological Sciences | PNAS Plus
Journal Article