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Journal of Heterocyclic Chemistry, ISSN 0022-152X, 09/2017, Volume 54, Issue 5, pp. 2867 - 2873
Reaction of phenoxyacetic acid hydrazide with isocyanate was used to the synthesis of new semicarbazide derivatives. Cyclization of these compounds in a 2%... 
CHEMISTRY, ORGANIC | AGENTS | ARYL | TRIAZOLE | AROMATASE INHIBITORS | PRIMAQUINE | Isocyanates | Hydroxides | Triazoles | Analysis
Journal Article
Journal of Liquid Chromatography & Related Technologies, ISSN 1082-6076, 07/2015, Volume 38, Issue 12, pp. 1199 - 1206
Newly obtained derivatives of N-substituted amides of 3-(3-ethylthio-1,2,4-triazol-5-yl)propenoic acid were analyzed by reversed phase high performance liquid... 
RP-HPLC | lipophilicity | activity | 1,2,4-triazole | RP-TLC | chromatography | PHASE LIQUID-CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | ACID | BEHAVIOR | DRUG DISCOVERY | BIOCHEMICAL RESEARCH METHODS | THIN-LAYER-CHROMATOGRAPHY | N-SUBSTITUTED AMIDES | SYSTEMS | VALUES | TOOL | Mass spectrometry | Chromatography | Extrapolation | Methyl alcohol | Mathematical analysis | Derivatives | Lipophilicity | Standards | Computer programs
Journal Article
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 06/2017, Volume 24, Issue 18, pp. 1948 - 1982
Infectious diseases are one of the most important and urgent health problems in the world. According to the World Health Organization (WHO) statistics,... 
Antibacterial compounds | Antibacterial activity | Antibacterial drug target | Antibiotics resistance | Structure-activity relationship | Infectious diseases treatment | CHEMISTRY, MEDICINAL | antibiotics resistance | antibacterial compounds | BACTERIAL-CELL DIVISION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN SYNTHASE III | DNA-GYRASE INHIBITORS | infectious diseases treatment | RESISTANT STAPHYLOCOCCUS-AUREUS | antibacterial drug target | D-GLUTAMIC ACID | GRAM-NEGATIVE BACTERIA | SMALL-MOLECULE INHIBITORS | UDP-N-ACETYLGLUCOSAMINE | PHARMACOLOGY & PHARMACY | POTENTIAL FABH INHIBITORS | structure-activity relationship | STRUCTURE-BASED DESIGN | Peptidoglycan - metabolism | Gram-Positive Bacteria - drug effects | Humans | Enzyme Inhibitors - pharmacology | Drug Resistance, Bacterial | Ribosomes - metabolism | Drug Discovery - methods | Structure-Activity Relationship | Gram-Negative Bacteria - drug effects | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Ribosomes - drug effects | Anti-Bacterial Agents - pharmacology | Klebsiella | Drugs | Pneumonia | Health problems | Sanitation | Outbreaks | Infections | Urinary tract | Vaccines | Structure-activity relationships | Drug resistance | Drug development | Antibacterial materials | Living conditions | E coli | Parasitic diseases | Bacteria | Strains (organisms) | Bacterial infections | Markets | Side effects | Infectious diseases | Antibiotics | Fatalities | Actinomycetes | Drug discovery
Journal Article
Journal of the Chinese Chemical Society, ISSN 0009-4536, 03/2014, Volume 61, Issue 3, pp. 369 - 376
The novel N‐(substituted‐thioureido)aminobicyclo dicarboximide and 3,4‐disubstituted 1,2,4‐triazolino‐5‐thione were synthesized and their antimicrobial and... 
Triazole | Antimicrobial activity | Dicarboximide | Synthesis | Antituberculosis activity | ACID | ANTICONVULSANT | RESISTANCE | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | AMIDES | Drugstores | Chemical properties | Oxalic acid | Triazoles | Analysis | Resveratrol
Journal Article
Journal of Liquid Chromatography & Related Technologies, ISSN 1082-6076, 11/2013, Volume 36, Issue 19, pp. 2639 - 2650
The retention behavior of biologically active pyrazoles has been determined using RP-18 TLC and IAM chromatography. The experimental parameters of... 
pyrazole | lipophilicity | antibacterial | carboxamide | activity | chromatography | CHEMISTRY, ANALYTICAL | DESIGN | LIQUID-CHROMATOGRAPHY | QSAR | RETENTION | BIOCHEMICAL RESEARCH METHODS | Mathematical models | Chromatography | Algorithms | Liquid chromatography | Derivatives | Antiinfectives and antibacterials | Lipophilicity | Pyrazole
Journal Article
Phosphorus, Sulfur, and Silicon and the Related Elements, ISSN 1042-6507, 11/2013, Volume 188, Issue 11, pp. 1661 - 1669
In a reaction of hydrazides of cyclohexylacetic acid 1 and phenylacetic acid 2 with isothiocyanates, respective thiosemicarbazide derivatives 3-18 were... 
isothiocyanates | 1,2,4-triazoles | antimicrobial activity | Thiosemicarbazides | DESIGN | 4-triazoles | TRIAZOLE | CHEMISTRY, ORGANIC | CHEMISTRY, INORGANIC & NUCLEAR | Antibacterial activity
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 01/2016, Volume 1104, pp. 24 - 32
The aim of this work are experimental and computational structural studies of new derivatives of 1-cyanoacetyl-4-arylsemicarbazide with potential anticancer... 
Spectroscopy | Tautomerism | Quantum chemical calculations | Semicarbazide | ENERGY | ACID | ANTIBACTERIAL ACTIVITY | CHEMISTRY, PHYSICAL | SEMICARBAZIDES | AGENTS | THEORETICAL INVESTIGATIONS | CYCLIZATION | Drugstores | Care and treatment | Raman spectroscopy | Analysis | Pharmacy | Cancer
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 8/2016, Volume 25, Issue 8, pp. 1666 - 1677
In this study, the antibacterial, cytotoxic and antiproliferative activities of novel thiosemicarbazide derivatives were assessed. Our results demonstrated... 
Biochemistry, general | Cell proliferation | Biomedicine | Thiosemicarbazide | Antibacterial activity | Cytotoxicity | Pharmacology/Toxicology | Cell Biology | BIOLOGICAL EVALUATION | CHEMISTRY, MEDICINAL | Lactates | Medical colleges | Dental caries | Chemotherapy | Pyridine | College teachers | Antibacterial agents | Cancer | Original Research
Journal Article
Acta Crystallographica Section E: Structure Reports Online, ISSN 1600-5368, 02/2013, Volume 69, Issue 2, pp. o155 - o156
The title compound, C11H13N3S, exists in the 5-thioxo tautomeric form. The benzene ring exhibits disorder with a refined ratio of 0.77 (2):0.23 (2) for... 
single-crystal X-ray study | mean σ(C-C) = 0.004 Å | T = 296 K | R factor = 0.047 | wR factor = 0.156 | data-to-parameter ratio = 17.6 | disorder in main residue | CRYSTALLOGRAPHY
Journal Article
Monatshefte für Chemie - Chemical Monthly, ISSN 0026-9247, 2/2010, Volume 141, Issue 2, pp. 199 - 203
In the reaction of 4,4′-diphenylmethane diisocyanate with carboxylic acid hydrazides, 4,4′-bis(1-substituted-semicarbazidyl)diphenylmethane derivatives were... 
Theoretical and Computational Chemistry | CNS activity | Chemistry | Analytical Chemistry | Physical Chemistry | Chemistry/Food Science, general | 1,2,4-Triazol-3-one | Inorganic Chemistry | Semicarbazide | Organic Chemistry | 1,2,4-Triazol-3 one | AGENTS | ANTITUBERCULOSIS ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY
Journal Article