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1. Full Text DNA methylation-based classification of central nervous system tumours
by Capper, David and Jones, David T. W and Sill, Martin and Hovestadt, Volker and Schrimpf, Daniel and Sturm, Dominik and Koelsche, Christian and Sahm, Felix and Chavez, Lukas and Reuss, David E and Kratz, Annekathrin and Wefers, Annika K and Huang, Kristin and Pajtler, Kristian W and Schweizer, Leonille and Stichel, Damian and Olar, Adriana and Engel, Nils W and Lindenberg, Kerstin and Harter, Patrick N and Braczynski, Anne K and Plate, Karl H and Dohmen, Hildegard and Garvalov, Boyan K and Coras, Roland and Hölsken, Annett and Hewer, Ekkehard and Bewerunge-Hudler, Melanie and Schick, Matthias and Fischer, Roger and Beschorner, Rudi and Schittenhelm, Jens and Staszewski, Ori and Wani, Khalida and Varlet, Pascale and Pages, Melanie and Temming, Petra and Lohmann, Dietmar and Selt, Florian and Witt, Hendrik and Milde, Till and Witt, Olaf and Aronica, Eleonora and Giangaspero, Felice and Rushing, Elisabeth and Scheurlen, Wolfram and Geisenberger, Christoph and Rodriguez, Fausto J and Becker, Albert and Preusser, Matthias and Haberler, Christine and Bjerkvig, Rolf and Cryan, Jane and Farrell, Michael and Deckert, Martina and Hench, Jürgen and Frank, Stephan and Serrano, Jonathan and Kannan, Kasthuri and Tsirigos, Aristotelis and Brück, Wolfgang and Hofer, Silvia and Brehmer, Stefanie and Seiz-Rosenhagen, Marcel and Hänggi, Daniel and Hans, Volkmar and Rozsnoki, Stephanie and Hansford, Jordan R and Kohlhof, Patricia and Kristensen, Bjarne W and Lechner, Matt and Lopes, Beatriz and Mawrin, Christian and Ketter, Ralf and Kulozik, Andreas and Khatib, Ziad and Heppner, Frank and Koch, Arend and Jouvet, Anne and Keohane, Catherine and Mühleisen, Helmut and Mueller, Wolf and Pohl, Ute and Prinz, Marco and Benner, Axel and Zapatka, Marc and Gottardo, Nicholas G and Driever, Pablo Hernáiz and Kramm, Christof M and Müller, Hermann L and Rutkowski, Stefan and Von Hoff, Katja and Frühwald, Michael C and Gnekow, Astrid and Fleischhack, Gudrun and Tippelt, Stephan and Calaminus, Gabriele and Monoranu, Camelia-Maria and Perry, Arie and Jones, Chris and ...
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7697, pp. 469 - 474
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous... 
MOLECULAR CLASSIFICATION | MULTICENTER | ENTITY | GLIOMA | MULTIDISCIPLINARY SCIENCES | PILOCYTIC ASTROCYTOMA | CLASS PROBABILITY ESTIMATION | SUBGROUPS | MEDULLOBLASTOMA | EXPRESSION | BIOCONDUCTOR | Central Nervous System Neoplasms - classification | Reproducibility of Results | Central Nervous System Neoplasms - genetics | Humans | Middle Aged | Child, Preschool | Infant | Male | Unsupervised Machine Learning | Young Adult | Central Nervous System Neoplasms - pathology | DNA Methylation | Adolescent | Aged, 80 and over | Adult | Female | Aged | Central Nervous System Neoplasms - diagnosis | Child | Cohort Studies | Genetic aspects | Nucleotide sequencing | Diagnosis | Methylation | Observations | Methods | DNA sequencing | Tumors | Cancer | Analysis | DNA | Machine learning | Central nervous system | Classifiers | Brain cancer | Standardization | Clinical trials | Probability | Data processing | Nervous system | Genomes | Gene expression | Generalized linear models | Learning algorithms | Classification | Diagnostic software | DNA methylation | Diagnostic systems | Bioinformatics | Deoxyribonucleic acid--DNA
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2. Full Text Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
by Klionsky, Daniel J and Abdelmohsen, Kotb and Abe, Akihisa and Abedin, Md Joynal and Abeliovich, Hagai and Acevedo Arozena, Abraham and Adachi, Hiroaki and Adams, Christopher M and Adams, Peter D and Adeli, Khosrow and Adhihetty, Peter J and Adler, Sharon G and Agam, Galila and Agarwal, Rajesh and Aghi, Manish K and Agnello, Maria and Agostinis, Patrizia and Aguilar, Patricia V and Aguirre-Ghiso, Julio and Airoldi, Edoardo M and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akporiaye, Emmanuel T and Al-Rubeai, Mohamed and Albaiceta, Guillermo M and Albanese, Chris and Albani, Diego and Albert, Matthew L and Aldudo, Jesus and Algül, Hana and Alirezaei, Mehrdad and Alloza, Iraide and Almasan, Alexandru and Almonte-Beceril, Maylin and Alnemri, Emad S and Alonso, Covadonga and Altan-Bonnet, Nihal and Altieri, Dario C and Alvarez, Silvia and Alvarez-Erviti, Lydia and Alves, Sandro and Amadoro, Giuseppina and Amano, Atsuo and Amantini, Consuelo and Ambrosio, Santiago and Amelio, Ivano and Amer, Amal O and Amessou, Mohamed and Amon, Angelika and An, Zhenyi and Anania, Frank A and Andersen, Stig U and Andley, Usha P and Andreadi, Catherine K and Andrieu-Abadie, Nathalie and Anel, Alberto and Ann, David K and Anoopkumar-Dukie, Shailendra and Antonioli, Manuela and Aoki, Hiroshi and Apostolova, Nadezda and Aquila, Saveria and Aquilano, Katia and Araki, Koichi and Arama, Eli and Aranda, Agustin and Araya, Jun and Arcaro, Alexandre and Arias, Esperanza and Arimoto, Hirokazu and Ariosa, Aileen R and Armstrong, Jane L and Arnould, Thierry and Arsov, Ivica and Asanuma, Katsuhiko and Askanas, Valerie and Asselin, Eric and Atarashi, Ryuichiro and Atherton, Sally S and Atkin, Julie D and Attardi, Laura D and Auberger, Patrick and Auburger, Georg and Aurelian, Laure and Autelli, Riccardo and Avagliano, Laura and Avantaggiati, Maria Laura and Avrahami, Limor and Awale, Suresh and Azad, Neelam and Bachetti, Tiziana and Backer, Jonathan M and Bae, Dong-Hun and Bae, Jae-sung and Bae, Ok-Nam and Bae, Soo Han and Baehrecke, Eric H and Baek, Seung-Hoon and Baghdiguian, Stephen and Bagniewska-Zadworna, Agnieszka and ... and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Diagnostikcentrum and Klinisk patologi och klinisk genetik and Institutionen för medicin och hälsa and Avdelningen för läkemedelsforskning and Avdelningen för cellbiologi
Autophagy, ISSN 1554-8627, 01/2016, Volume 12, Issue 1, pp. 1 - 222
stress | chaperone-mediated autophagy | vacuole | autolysosome | macroautophagy | flux | autophagosome | LC3 | lysosome | phagophore | Phagophore | Lysosome | Autolysosome | Flux | Autophagosome | Vacuole | Chaperonemediated autophagy | Macroautophagy | Stress | ACTIVATED PROTEIN-KINASE | ENDOPLASMIC-RETICULUM STRESS | STARVATION-INDUCED AUTOPHAGY | GLUCAGON-INDUCED AUTOPHAGY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | LIFE-SPAN EXTENSION | BETAINE HOMOCYSTEINE METHYLTRANSFERASE | VACUOLAR MEMBRANE DYNAMICS | NF-KAPPA-B | Autophagy - physiology | Biological Assay - methods | Animals | Biological Assay - standards | Computer Simulation | Humans | Life Sciences | Medical and Health Sciences | Medicin och hälsovetenskap
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3. Full Text MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism
by Bandopadhayay, Pratiti and Ramkissoon, Lori A and Jain, Payal and Bergthold, Guillaume and Wala, Jeremiah and Zeid, Rhamy and Schumacher, Steven E and Urbanski, Laura and O'Rourke, Ryan and Gibson, William J and Pelton, Kristine and Ramkissoon, Shakti H and Han, Harry J and Zhu, Yuankun and Choudhari, Namrata and Silva, Amanda and Boucher, Katie and Henn, Rosemary E and Kang, Yun Jee and Knoff, David and Paolella, Brenton R and Gladden-Young, Adrianne and Varlet, Pascale and Pages, Melanie and Horowitz, Peleg M and Federation, Alexander and Malkin, Hayley and Tracy, Adam A and Seepo, Sara and Ducar, Matthew and Van Hummelen, Paul and Santi, Mariarita and Buccoliero, Anna Maria and Scagnet, Mirko and Bowers, Daniel C and Giannini, Caterina and Puget, Stephanie and Hawkins, Cynthia and Tabori, Uri and Klekner, Almos and Bognar, Laszlo and Burger, Peter C and Eberhart, Charles and Rodriguez, Fausto J and Hill, D. Ashley and Mueller, Sabine and Haas-Kogan, Daphne A and Phillips, Joanna J and Santagata, Sandro and Stiles, Charles D and Bradner, James E and Jabado, Nada and Goren, Alon and Grill, Jacques and Ligon, Azra H and Goumnerova, Liliana and Waanders, Angela J and Storm, Phillip B and Kieran, Mark W and Ligon, Keith L and Beroukhim, Rameen and Resnick, Adam C
Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 3, pp. 273 - 282
Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent genetic drivers. We performed genomic analysis of new and published data... 
TRANSFORMATION | PROTEIN | GENE | GENETICS & HEREDITY | C-MYB | ADENOID CYSTIC CARCINOMA | NEURAL STEM-CELL | BET BROMODOMAIN INHIBITION | CANCER | LOW-GRADE GLIOMAS | V-MYB | RNA-Binding Proteins - genetics | Humans | Oncogene Proteins, Fusion - biosynthesis | Carcinogenesis - genetics | Gene Expression Regulation, Neoplastic | Glioma - genetics | RNA-Binding Proteins - biosynthesis | Exome - genetics | Comparative Genomic Hybridization | Oncogene Proteins, Fusion - genetics | Gene Rearrangement | Glioma - pathology | Oncogene Proteins v-myb - biosynthesis | Cell Line, Tumor | Oncogene Proteins v-myb - genetics | High-Throughput Nucleotide Sequencing | Mutation | Child | Epigenetic inheritance | Gliomas | Genetic research | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Gene expression | Health aspects | Proteins | Pediatrics | Medical research | Transcription factors | Brain research | Brain cancer | Genomes | Kinases | Tumors | Cancer
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4. Full Text Comprehensive analysis of the MLH1 promoter region in 480 patients with colorectal cancer and 1150 controls reveals new variants including one with a heritable constitutional MLH1 epimutation
by Morak, Monika and Ibisler, Ayseguel and Keller, Gisela and Jessen, Ellen and Laner, Andreas and Gonzales-Fassrainer, Daniela and Locher, Melanie and Massdorf, Trisari and Nissen, Anke M and Benet-Pagès, Anna and Holinski-Feder, Elke
Journal of Medical Genetics, ISSN 0022-2593, 04/2018, Volume 55, Issue 4, pp. 240 - 248
BackgroundGermline defects in MLH1, MSH2, MSH6 and PMS2 predisposing for Lynch syndrome (LS) are mainly based on sequence changes, whereas a constitutional... 
genetic screening/counselling | cancer: colon | genetics | epigenetics | HNPCC | METHYLATION | GENOMIC REARRANGEMENTS | MICROSATELLITE INSTABILITY | GENETICS & HEREDITY | MISMATCH REPAIR GENE | SEQUENCE VARIANTS | HMLH1 | LYNCH SYNDROME | GERMLINE EPIMUTATIONS | IDENTIFICATION | Phenotypes | MLH1 protein | Colorectal carcinoma | MSH2 protein | Colorectal cancer | Gene expression | Proteins | Gene silencing | MSH6 protein | Classification | Alleles | DNA methylation | Mutation | Methylation | Deoxyribonucleic acid--DNA | CpG islands | Tumors
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