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helicobacter pylori (9) 9
humans (8) 8
toxin (7) 7
hela cells (6) 6
vacuolating cytotoxin (6) 6
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protein structure, tertiary (2) 2
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/1998, Volume 95, Issue 17, pp. 10212 - 10217
The Helicobacter pylori toxin VacA causes vacuolar degeneration in mammalian cell lines in vitro and plays a key role in peptic ulcer disease. Two alleles, m1... 
Cytotoxins | Receptors | HEK293 cells | Toxicity | Epithelial cells | Cell lines | HeLa cells | Amino acids | Toxins | Kidney cells | Mosaic structure | STRAINS | VACA | RESISTANT | mosaic structure | PROTEIN | ACID | GENE | TOXIN | MULTIDISCIPLINARY SCIENCES | DISEASE | ULCER | BINDING | Bacterial toxins | Helicobacter pylori | Physiological aspects | Peptic ulcer | Serum | Research | Cytoplasm
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 1999, Volume 290, Issue 2, pp. 459 - 470
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 01/2002, Volume 206, Issue 2, pp. 253 - 258
Abstract There are two functionally different alleles of the Helicobacter pylori vacA gene, which code for proteins with different in target cell specificity.... 
Toxin | VacA | Evolution | Geographic variation | Helicobacter pylori | Genes | Amino acid sequence | Geographical variations | Phylogeny | Clustering | Gene polymorphism | Clear cutting | Horizontal transfer | Alleles | Phylogenetics | VacA protein | Deoxyribonucleic acid--DNA | Polymorphism | Anomalies
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/1998, Volume 95, Issue 17, p. 10212
  The Helicobacter pylori toxin VacA causes vacuolar degeneration in mammalian cell lines in vitro and plays a key role in peptic ulcer disease. Two alleles,... 
Microbiology | Ulcers | Rodents | Bacteria
Journal Article
Infection and Immunity, ISSN 0019-9567, 11/1998, Volume 66, Issue 11, pp. 5547 - 5550
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
Journal Article
Infection and Immunity, ISSN 0019-9567, 06/2000, Volume 68, Issue 6, p. 3754
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 08/1998, Volume 165, Issue 1, pp. 79 - 84
Abstract The vacuolating cytotoxin (VacA) is a major virulence factor of Helicobacter pylori which is not yet well characterised and is difficult to obtain in... 
Helicobacter pylori | Immunoaffinity | Cytotoxin | Time dependence | Cell culture | Elution | Purification | Affinity chromatography | Virulence | pH | Monoclonal antibodies | Monomers
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 01/2002, Volume 206, Issue 2, pp. 253 - 258
Journal Article
FEMS Microbiology Letters, ISSN 0378-1097, 08/1998, Volume 165, Issue 1, pp. 79 - 84
Journal Article
Chinese Journal of Digestive Diseases, ISSN 1443-9611, 03/2001, Volume 2, Issue 1, pp. 17 - 21
OBJECTIVE: To characterize the vacA alleles present in Chinese Helicobacter pylori strains and to compare the allelic variation in the vacA gene of Chinese... 
vacuolating toxin | sequence analysis | vacuolating cytotoxin gene (vacA) | Helicobacter pylori | allele | genotype
Journal Article
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