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Publication DateThe Laryngoscope, ISSN 0023-852X, 06/2017, Volume 127, Issue 6, pp. 1334 - 1338
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Loading RightsAnnual Review of Pathology: Mechanisms of Disease, ISSN 1553-4006, 02/2009, Volume 4, Issue 1, pp. 49 - 70
The prototypic head and neck squamous cell carcinoma (HNSCC) arises from the mucosal lining of the upper aerodigestive tract, demonstrates squamous...
Pathology | Genetics | Human papillomavirus | Vaccines | Tyrosine kinase inhibitors | SQUAMOUS-CELL-CARCINOMA | pathology | vaccines | UPPER AERODIGESTIVE TRACT | COMMON CLONAL ORIGIN | tyrosine kinase inhibitors | PHASE-II TRIAL | genetics | SURGICAL MARGINS | 2ND PRIMARY TUMORS | human papillomavirus | ORAL PREMALIGNANT LESIONS | TYROSINE KINASE INHIBITOR | FACTOR RECEPTOR EXPRESSION | HUMAN-PAPILLOMAVIRUS INFECTION | Smoking - adverse effects | Predictive Value of Tests | Age Factors | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Male | Patient Selection | Cell Transformation, Neoplastic - genetics | Head and Neck Neoplasms - epidemiology | Female | Genetic Predisposition to Disease | Papillomavirus Infections - complications | Carcinoma, Squamous Cell - epidemiology | Risk Factors | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Alcohol Drinking - adverse effects | Head and Neck Neoplasms - pathology | Phenotype | Sex Factors | Head and Neck Neoplasms - genetics | Biomarkers, Tumor - genetics | Cell Transformation, Neoplastic - pathology | Care and treatment | Head and neck cancer | Development and progression | Research | Diagnosis | Pathology, Molecular | Cancer
Pathology | Genetics | Human papillomavirus | Vaccines | Tyrosine kinase inhibitors | SQUAMOUS-CELL-CARCINOMA | pathology | vaccines | UPPER AERODIGESTIVE TRACT | COMMON CLONAL ORIGIN | tyrosine kinase inhibitors | PHASE-II TRIAL | genetics | SURGICAL MARGINS | 2ND PRIMARY TUMORS | human papillomavirus | ORAL PREMALIGNANT LESIONS | TYROSINE KINASE INHIBITOR | FACTOR RECEPTOR EXPRESSION | HUMAN-PAPILLOMAVIRUS INFECTION | Smoking - adverse effects | Predictive Value of Tests | Age Factors | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Male | Patient Selection | Cell Transformation, Neoplastic - genetics | Head and Neck Neoplasms - epidemiology | Female | Genetic Predisposition to Disease | Papillomavirus Infections - complications | Carcinoma, Squamous Cell - epidemiology | Risk Factors | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Alcohol Drinking - adverse effects | Head and Neck Neoplasms - pathology | Phenotype | Sex Factors | Head and Neck Neoplasms - genetics | Biomarkers, Tumor - genetics | Cell Transformation, Neoplastic - pathology | Care and treatment | Head and neck cancer | Development and progression | Research | Diagnosis | Pathology, Molecular | Cancer
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Loading RightsCancer Cytopathology, ISSN 1934-662X, 07/2017, Volume 125, Issue 7, pp. 529 - 533
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Loading RightsJAMA, ISSN 0098-7484, 04/2013, Volume 309, Issue 14, pp. 1493 - 1501
IMPORTANCE BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in PTC-related patient mortality has not been established....
PATHOGENESIS | CELLS | MEDICINE, GENERAL & INTERNAL | BRAF(V600E) MUTATION | RISK | RECURRENCE | COHORT | HIGH PREVALENCE | CARCINOMA | GENE METHYLATION | GENOME | Thyroid Neoplasms - mortality | Neoplasm Invasiveness | Humans | Middle Aged | Carcinoma - mortality | Male | Risk | Lymphatic Metastasis | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Carcinoma, Papillary | DNA Mutational Analysis | Proto-Oncogene Proteins B-raf - genetics | Adult | Carcinoma - genetics | Female | Aged | Retrospective Studies | Mutation | Carcinoma - pathology | Thyroid Neoplasms - pathology | Care and treatment | Thyroid cancer | United States | Mortality | Analysis | Research | Patients | Mutation (Biology) | Genes
PATHOGENESIS | CELLS | MEDICINE, GENERAL & INTERNAL | BRAF(V600E) MUTATION | RISK | RECURRENCE | COHORT | HIGH PREVALENCE | CARCINOMA | GENE METHYLATION | GENOME | Thyroid Neoplasms - mortality | Neoplasm Invasiveness | Humans | Middle Aged | Carcinoma - mortality | Male | Risk | Lymphatic Metastasis | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Carcinoma, Papillary | DNA Mutational Analysis | Proto-Oncogene Proteins B-raf - genetics | Adult | Carcinoma - genetics | Female | Aged | Retrospective Studies | Mutation | Carcinoma - pathology | Thyroid Neoplasms - pathology | Care and treatment | Thyroid cancer | United States | Mortality | Analysis | Research | Patients | Mutation (Biology) | Genes
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Loading RightsOral Oncology, ISSN 1368-8375, 2013, Volume 49, Issue 8, pp. 723 - 725
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Loading RightsCancer Cytopathology, ISSN 1934-662X, 07/2017, Volume 125, Issue 7, pp. 529 - 533
The evaluation of programmed cell death ligand 1 has a potential role in the application of immune checkpoint inhibitors for select cancers of the head and...
LUNG-CANCER | PEMBROLIZUMAB | MELANOMA | ONCOLOGY | OPEN-LABEL | PATHOLOGY | NIVOLUMAB | BLOCKADE | CLINICAL ACTIVITY | CARCINOMA | EXPRESSION | PHASE-2 TRIAL | Squamous Cell Carcinoma of Head and Neck | B7-H1 Antigen - analysis | Biomarkers, Tumor - analysis | Humans
LUNG-CANCER | PEMBROLIZUMAB | MELANOMA | ONCOLOGY | OPEN-LABEL | PATHOLOGY | NIVOLUMAB | BLOCKADE | CLINICAL ACTIVITY | CARCINOMA | EXPRESSION | PHASE-2 TRIAL | Squamous Cell Carcinoma of Head and Neck | B7-H1 Antigen - analysis | Biomarkers, Tumor - analysis | Humans
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Loading RightsCancer Research, ISSN 0008-5472, 03/2013, Volume 73, Issue 6, pp. 1733 - 1741
Human papillomavirus-associated head and neck squamous cell carcinomas (HPV-HNSCC) originate in the tonsils, the major lymphoid organ that orchestrates...
SURVIVAL | OROPHARYNGEAL | ONCOLOGY | SAFETY | B7-H1 EXPRESSION | PTEN | ANTIBODY | HUMAN-PAPILLOMAVIRUS | BLOCKADE | CANCER | T-CELLS | Immunohistochemistry | B7-H1 Antigen - physiology | Head and Neck Neoplasms - virology | Carcinoma, Squamous Cell - virology | Humans | Interferon-gamma - metabolism | Papillomaviridae - isolation & purification | Programmed Cell Death 1 Receptor - physiology | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - immunology | Flow Cytometry | CD8-Positive T-Lymphocytes - immunology | immune checkpoint | PD-L1 | oropharyngeal cancers | squamous cell carcinomas | adapative resistance | PD-1 | head and neck cancers | HPV
SURVIVAL | OROPHARYNGEAL | ONCOLOGY | SAFETY | B7-H1 EXPRESSION | PTEN | ANTIBODY | HUMAN-PAPILLOMAVIRUS | BLOCKADE | CANCER | T-CELLS | Immunohistochemistry | B7-H1 Antigen - physiology | Head and Neck Neoplasms - virology | Carcinoma, Squamous Cell - virology | Humans | Interferon-gamma - metabolism | Papillomaviridae - isolation & purification | Programmed Cell Death 1 Receptor - physiology | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Squamous Cell - immunology | Head and Neck Neoplasms - immunology | Flow Cytometry | CD8-Positive T-Lymphocytes - immunology | immune checkpoint | PD-L1 | oropharyngeal cancers | squamous cell carcinomas | adapative resistance | PD-1 | head and neck cancers | HPV
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Loading RightsJournal of Clinical Oncology, ISSN 0732-183X, 08/2014, Volume 32, Issue 23, pp. 2408 - 2415
Purpose To better understand oral human papillomavirus (HPV) infection and cancer risk among long-term sexual partners of patients with HPV-positive...
UNITED-STATES | HEAD | TRANSMISSION | RISK-FACTORS | ONCOLOGY | YOUNG MEN | TONSILLAR CANCER | ADULTS | PREVALENCE | NECK-CANCER | Prevalence | Prospective Studies | HIV Infections - virology | Humans | Middle Aged | Risk Factors | Male | Oropharyngeal Neoplasms - virology | Human papillomavirus 16 - isolation & purification | Female | Papillomavirus Infections - virology | Aged | Sexual Partners | Human papillomavirus 16 - genetics | ORIGINAL REPORTS | Hnc1
UNITED-STATES | HEAD | TRANSMISSION | RISK-FACTORS | ONCOLOGY | YOUNG MEN | TONSILLAR CANCER | ADULTS | PREVALENCE | NECK-CANCER | Prevalence | Prospective Studies | HIV Infections - virology | Humans | Middle Aged | Risk Factors | Male | Oropharyngeal Neoplasms - virology | Human papillomavirus 16 - isolation & purification | Female | Papillomavirus Infections - virology | Aged | Sexual Partners | Human papillomavirus 16 - genetics | ORIGINAL REPORTS | Hnc1
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Loading RightsOncoImmunology, ISSN 2162-4011, 05/2013, Volume 2, Issue 5, p. e24065
Human papillomavirus (HPV) types associated with head and neck cancer generally induce a robust immune response. Despite the establishment of such an...
PD-L1 | head and neck cancer | PD-1 | HPV | immune checkpoints | Head and neck cancer | Immune checkpoints | ONCOLOGY | SAFETY | ANTIBODY | HUMAN-PAPILLOMAVIRUS | IMMUNOLOGY | Author's View
PD-L1 | head and neck cancer | PD-1 | HPV | immune checkpoints | Head and neck cancer | Immune checkpoints | ONCOLOGY | SAFETY | ANTIBODY | HUMAN-PAPILLOMAVIRUS | IMMUNOLOGY | Author's View
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The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment
Oral Oncology, ISSN 1368-8375, 2016, Volume 61, pp. 152 - 158
Highlights • Targeting of the PD-1:PD-L1 axis demonstrates promise in the treatment of head and neck cancer patients. • PD-1/PD-L1 blockade enhances the...
Otolaryngology | Hematology, Oncology and Palliative Medicine | Squamous cell carcinoma | Immune checkpoint | Immunotherapy | PD-L1 | PD-L2 | Head and neck cancer | B7-H1 | PD-1 | TUMOR-INFILTRATING LYMPHOCYTES | CTLA-4 COUNTER-RECEPTOR | ONCOLOGY | HPV-ASSOCIATED HEAD | DENTISTRY, ORAL SURGERY & MEDICINE | OROPHARYNGEAL CANCER | SQUAMOUS-CELL CARCINOMA | B7 FAMILY | COSTIMULATORY MOLECULE | PROGRAMMED DEATH-1 LIGAND-1 | T-CELLS | CLINICAL-SIGNIFICANCE | Tumor Microenvironment | Head and Neck Neoplasms - immunology | B7-H1 Antigen - antagonists & inhibitors | Humans | Head and Neck Neoplasms - therapy | Programmed Cell Death 1 Ligand 2 Protein - antagonists & inhibitors | Care and treatment | Drug therapy | Cancer | Cell death | Monoclonal antibodies
Otolaryngology | Hematology, Oncology and Palliative Medicine | Squamous cell carcinoma | Immune checkpoint | Immunotherapy | PD-L1 | PD-L2 | Head and neck cancer | B7-H1 | PD-1 | TUMOR-INFILTRATING LYMPHOCYTES | CTLA-4 COUNTER-RECEPTOR | ONCOLOGY | HPV-ASSOCIATED HEAD | DENTISTRY, ORAL SURGERY & MEDICINE | OROPHARYNGEAL CANCER | SQUAMOUS-CELL CARCINOMA | B7 FAMILY | COSTIMULATORY MOLECULE | PROGRAMMED DEATH-1 LIGAND-1 | T-CELLS | CLINICAL-SIGNIFICANCE | Tumor Microenvironment | Head and Neck Neoplasms - immunology | B7-H1 Antigen - antagonists & inhibitors | Humans | Head and Neck Neoplasms - therapy | Programmed Cell Death 1 Ligand 2 Protein - antagonists & inhibitors | Care and treatment | Drug therapy | Cancer | Cell death | Monoclonal antibodies
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Loading RightsAmerican Journal of Surgical Pathology, ISSN 0147-5185, 02/2013, Volume 37, Issue 2, pp. 185 - 192
High-risk human papillomavirus (HPV) is an established cause of head and neck carcinomas arising in the oropharynx. The presence of HPV has also been reported...
sinonasal undifferentiated carcinoma | adenoid cystic carcinoma | human papillomavirus | sinonasal carcinoma | squamous cell carcinoma | SQUAMOUS-CELL-CARCINOMA | SURGERY | HEAD | PARANASAL SINUSES | PATHOLOGY | HPV | PARA-NASAL SINUSES | P16 EXPRESSION | OROPHARYNGEAL CANCER | NECK | MALIGNANT NEOPLASMS | Tissue Array Analysis | Humans | Middle Aged | Carcinoma, Small Cell - virology | DNA, Viral - analysis | Male | Neoplasms, Squamous Cell - virology | Carcinoma, Adenoid Cystic - virology | Paranasal Sinus Neoplasms - virology | Papillomaviridae - genetics | Papillomavirus Infections - pathology | In Situ Hybridization | Aged, 80 and over | Adult | Female | Papillomavirus Infections - virology | Neoplasms, Squamous Cell - pathology | Carcinoma, Adenoid Cystic - pathology | Carcinoma, Small Cell - metabolism | Comorbidity | Carcinoma, Adenoid Cystic - metabolism | Survival Rate | Papillomaviridae - isolation & purification | Paranasal Sinus Neoplasms - pathology | Papillomavirus Infections - metabolism | Paranasal Sinus Neoplasms - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Aged | Carcinoma, Small Cell - pathology | Neoplasms, Squamous Cell - metabolism | Human papillomavirus
sinonasal undifferentiated carcinoma | adenoid cystic carcinoma | human papillomavirus | sinonasal carcinoma | squamous cell carcinoma | SQUAMOUS-CELL-CARCINOMA | SURGERY | HEAD | PARANASAL SINUSES | PATHOLOGY | HPV | PARA-NASAL SINUSES | P16 EXPRESSION | OROPHARYNGEAL CANCER | NECK | MALIGNANT NEOPLASMS | Tissue Array Analysis | Humans | Middle Aged | Carcinoma, Small Cell - virology | DNA, Viral - analysis | Male | Neoplasms, Squamous Cell - virology | Carcinoma, Adenoid Cystic - virology | Paranasal Sinus Neoplasms - virology | Papillomaviridae - genetics | Papillomavirus Infections - pathology | In Situ Hybridization | Aged, 80 and over | Adult | Female | Papillomavirus Infections - virology | Neoplasms, Squamous Cell - pathology | Carcinoma, Adenoid Cystic - pathology | Carcinoma, Small Cell - metabolism | Comorbidity | Carcinoma, Adenoid Cystic - metabolism | Survival Rate | Papillomaviridae - isolation & purification | Paranasal Sinus Neoplasms - pathology | Papillomavirus Infections - metabolism | Paranasal Sinus Neoplasms - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Aged | Carcinoma, Small Cell - pathology | Neoplasms, Squamous Cell - metabolism | Human papillomavirus
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Loading RightsHead & Neck, ISSN 1043-3074, 07/2008, Volume 30, Issue 7, pp. 898 - 903
Background. Cystic lymph node metastases have been associated with tonsil cancer. A subset of oropharyngeal cancers contain human papillomavirus (HPV) DNA. The...
cystic neck mass | oropharyngeal cancer | head and neck cancer | lymph nodal metastasis | human papillomavirus | Head and neck cancer | Human papillomavirus | Cystic neck mass | Lymph nodal metastasis | Oropharyngeal cancer | SURGERY | NEEDLE ASPIRATION CYTOLOGY | CERVICAL CYSTS | HUMAN-PAPILLOMAVIRUS | TONSILLAR CARCINOMA | ORIGIN | OTORHINOLARYNGOLOGY | SQUAMOUS-CELL CARCINOMA | Immunohistochemistry | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Prognosis | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Male | Tomography, X-Ray Computed | Papillomavirus Infections - diagnosis | Carcinoma, Squamous Cell - mortality | Female | Retrospective Studies | Tonsillar Neoplasms - pathology | Risk Assessment | Papillomavirus Infections - epidemiology | Lymph Nodes - virology | Lymphatic Metastasis | Tonsillar Neoplasms - surgery | Head and Neck Neoplasms - pathology | Magnetic Resonance Imaging | Tonsillar Neoplasms - virology | Survival Analysis | Carcinoma, Squamous Cell - secondary | Aged | Biopsy, Needle | Head and Neck Neoplasms - mortality | Neoplasm Staging | Head and Neck Neoplasms - surgery | Cohort Studies | Head | Tonsil | DNA | Neck | Cervix | Lymph nodes | Metastases | Tumors
cystic neck mass | oropharyngeal cancer | head and neck cancer | lymph nodal metastasis | human papillomavirus | Head and neck cancer | Human papillomavirus | Cystic neck mass | Lymph nodal metastasis | Oropharyngeal cancer | SURGERY | NEEDLE ASPIRATION CYTOLOGY | CERVICAL CYSTS | HUMAN-PAPILLOMAVIRUS | TONSILLAR CARCINOMA | ORIGIN | OTORHINOLARYNGOLOGY | SQUAMOUS-CELL CARCINOMA | Immunohistochemistry | Head and Neck Neoplasms - virology | Lymph Nodes - pathology | Prognosis | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Male | Tomography, X-Ray Computed | Papillomavirus Infections - diagnosis | Carcinoma, Squamous Cell - mortality | Female | Retrospective Studies | Tonsillar Neoplasms - pathology | Risk Assessment | Papillomavirus Infections - epidemiology | Lymph Nodes - virology | Lymphatic Metastasis | Tonsillar Neoplasms - surgery | Head and Neck Neoplasms - pathology | Magnetic Resonance Imaging | Tonsillar Neoplasms - virology | Survival Analysis | Carcinoma, Squamous Cell - secondary | Aged | Biopsy, Needle | Head and Neck Neoplasms - mortality | Neoplasm Staging | Head and Neck Neoplasms - surgery | Cohort Studies | Head | Tonsil | DNA | Neck | Cervix | Lymph nodes | Metastases | Tumors
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Loading RightsThe Laryngoscope, ISSN 0023-852X, 06/2017, Volume 127, Issue 6, pp. 1334 - 1338
Objective To analyze the impact of adjuvant radiation therapy (RT) on overall survival (OS) and disease‐specific survival (DSS) in patients with verrucous...
T stage | head and neck cancer | survival | radiation therapy | oral cavity | Verrucous carcinoma | SEER | cancer | MEDICINE, RESEARCH & EXPERIMENTAL | HEAD | ANAPLASTIC TRANSFORMATION | RADIATION | OTORHINOLARYNGOLOGY | NECK | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Male | Carcinoma, Squamous Cell - radiotherapy | Neoplasm Recurrence, Local - mortality | Carcinoma, Verrucous - mortality | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Radiotherapy, Adjuvant - mortality | Mouth | Female | Mouth Neoplasms - radiotherapy | SEER Program | Cross-Sectional Studies | Carcinoma, Verrucous - radiotherapy | Kaplan-Meier Estimate | Treatment Outcome | Mouth Neoplasms - mortality | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Radiotherapy, Adjuvant - methods | Carcinoma, Verrucous - surgery | Mouth Neoplasms - surgery | Aged | Head and Neck Neoplasms - mortality | Head and Neck Neoplasms - surgery | Squamous cell carcinoma | Care and treatment | Analysis | Venture capital | Radiation | Radiotherapy | Epidemiology | Financial disclosure
T stage | head and neck cancer | survival | radiation therapy | oral cavity | Verrucous carcinoma | SEER | cancer | MEDICINE, RESEARCH & EXPERIMENTAL | HEAD | ANAPLASTIC TRANSFORMATION | RADIATION | OTORHINOLARYNGOLOGY | NECK | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Male | Carcinoma, Squamous Cell - radiotherapy | Neoplasm Recurrence, Local - mortality | Carcinoma, Verrucous - mortality | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Radiotherapy, Adjuvant - mortality | Mouth | Female | Mouth Neoplasms - radiotherapy | SEER Program | Cross-Sectional Studies | Carcinoma, Verrucous - radiotherapy | Kaplan-Meier Estimate | Treatment Outcome | Mouth Neoplasms - mortality | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Radiotherapy, Adjuvant - methods | Carcinoma, Verrucous - surgery | Mouth Neoplasms - surgery | Aged | Head and Neck Neoplasms - mortality | Head and Neck Neoplasms - surgery | Squamous cell carcinoma | Care and treatment | Analysis | Venture capital | Radiation | Radiotherapy | Epidemiology | Financial disclosure
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Loading RightsImmunity, ISSN 1074-7613, 12/2018, Volume 49, Issue 6, pp. 1148 - 1161.e7
Anti-PD-1 immune checkpoint blockers can induce sustained clinical responses in cancer but how they function remains incompletely understood. Here, we combined...
checkpoint | IFN-γ | non-canonical NF-κB | immunotherapy | cancer | IL-12 | anti-PD-1 | dendritic cell | BET | RESPONSES | CD40 | ACTIVATION | MACROPHAGES | INTERLEUKIN-12 | IMMUNOLOGY | TRANSCRIPTION FACTOR | EXPRESSION | PD-1 | REVEALS | Animal models | PD-1 protein | Crosstalk | Interleukin | Cytotoxicity | Lymphocytes T | Immunity | Experiments | Gene sequencing | Anticancer properties | Proteins | Cell activation | Lymphocytes | Immunotherapy | NF-κB protein | Pharmacodynamics | Cytokines | Dendritic cells | Research funding | Interleukin 12 | Pharmacology | Grants | Gene expression | Ribonucleic acid--RNA | Immune checkpoint | Microscopy | γ-Interferon | Antitumor activity | Interferon | Cancer | Tumors
checkpoint | IFN-γ | non-canonical NF-κB | immunotherapy | cancer | IL-12 | anti-PD-1 | dendritic cell | BET | RESPONSES | CD40 | ACTIVATION | MACROPHAGES | INTERLEUKIN-12 | IMMUNOLOGY | TRANSCRIPTION FACTOR | EXPRESSION | PD-1 | REVEALS | Animal models | PD-1 protein | Crosstalk | Interleukin | Cytotoxicity | Lymphocytes T | Immunity | Experiments | Gene sequencing | Anticancer properties | Proteins | Cell activation | Lymphocytes | Immunotherapy | NF-κB protein | Pharmacodynamics | Cytokines | Dendritic cells | Research funding | Interleukin 12 | Pharmacology | Grants | Gene expression | Ribonucleic acid--RNA | Immune checkpoint | Microscopy | γ-Interferon | Antitumor activity | Interferon | Cancer | Tumors
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Loading RightsAmerican Journal of Ophthalmology, ISSN 0002-9394, 04/2019, Volume 200, pp. 226 - 241
Novel cancer immunotherapies, called immune checkpoint inhibitors, have demonstrated clinical efficacy in the treatment of squamous cell carcinomas of the head...
HEAD | MANAGEMENT | PEMBROLIZUMAB | RECURRENT | PD-L1 EXPRESSION | OPHTHALMOLOGY | NIVOLUMAB | NECK-CANCER | Immunohistochemistry | Squamous cell carcinoma | Health aspects | Immunotherapy | Apoptosis | Cardiovascular disease | Ligands | Software | Ophthalmology | Patients | Endothelium | Tumors
HEAD | MANAGEMENT | PEMBROLIZUMAB | RECURRENT | PD-L1 EXPRESSION | OPHTHALMOLOGY | NIVOLUMAB | NECK-CANCER | Immunohistochemistry | Squamous cell carcinoma | Health aspects | Immunotherapy | Apoptosis | Cardiovascular disease | Ligands | Software | Ophthalmology | Patients | Endothelium | Tumors
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