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PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, pp. e0131241 - e0131241
Blocking the enzyme Fatty Acid Synthase (FASN) leads to apoptosis of HER2-positive breast carcinoma cells. The hypothesis is that blocking FASN, in combination... 
GROWTH-FACTOR RECEPTOR | ANTICANCER ACTIVITY | BODY-WEIGHT | GREEN TEA | CELLS | HER2-TARGETED THERAPY | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | OVARIAN-CANCER | TRASTUZUMAB RESISTANCE | Neoplasm Transplantation | Gallic Acid - pharmacology | Humans | Drug Resistance, Neoplasm | Dose-Response Relationship, Drug | Antibodies, Monoclonal, Humanized - pharmacology | Female | Antineoplastic Agents - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Trastuzumab - pharmacology | Gallic Acid - analogs & derivatives | Catechin - pharmacology | Sirolimus - analogs & derivatives | Neoplasm Invasiveness | Mice, SCID | Breast Neoplasms - drug therapy | Cell Adhesion | Sirolimus - pharmacology | Fatty Acid Synthase, Type I - antagonists & inhibitors | Naphthalenes - pharmacology | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Mice, Inbred NOD | Catechin - analogs & derivatives | Mice | Mutation | Quinazolines - pharmacology | Drugs | Enzymes | Catechin | Synthesis | Analysis | Breast cancer | Fatty acids | TOR protein | Biomedical research | Toxicity | AKT protein | Biochemistry | Kinases | Cancer therapies | Anticancer properties | Proteins | Breast carcinoma | Epidermal growth factor | Polyphenols | Biocompatibility | Epidermal growth factor receptors | Epigallocatechin-3-gallate | Extracellular signal-regulated kinase | ErbB-2 protein | Patients | Fatty-acid synthase | Molecular chains | Medicine | Signaling | Molecular modelling | Medical prognosis | Epigenetics | Breast | Antitumor activity | Ligands | Molecular biology | Trastuzumab | Cancer | Apoptosis | Tumors | Index Medicus | Cell interaction | Interaccions dels medicaments | Interacció cel·lular | Terapèutica | Drug interactions | Therapeutics | Càncer de mama
Journal Article
Revista Española de Cardiología, ISSN 0300-8932, 06/2019, Volume 72, Issue 6, pp. 499 - 499
Journal Article
Revista Espanola de Cardiologia, ISSN 0300-8932, 06/2019, Volume 72, Issue 6, p. 499
Journal Article
Revista Espanola de Cardiologia, ISSN 0300-8932, 05/2019, Volume 72, Issue 5, p. 419
Journal Article
Revista Española de Cardiología, ISSN 0300-8932, 05/2019, Volume 72, Issue 5, p. 419
Journal Article
Stem Cell Reports, ISSN 2213-6711, 05/2017, Volume 8, Issue 5, pp. 1392 - 1407
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2018, Volume 20, Issue 2, pp. 211 - 221
Journal Article
Spanish Journal of Cardiology (Revista Española de Cardiología, English Edition), ISSN 1885-5857, 2018, Volume 72, Issue 6, pp. 499 - 499
Journal Article
Spanish Journal of Cardiology (Revista Española de Cardiología, English Edition), ISSN 1885-5857, 2018, Volume 72, Issue 5, pp. 419 - 419
Journal Article
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 04/2019, Volume 18, Issue 4, pp. 771 - 779
The interaction of a drug with its target is critical to achieve drug efficacy. In cases where cellular environment influences target engagement, differences... 
DEPENDENT KINASE CDK6 | 1ST-LINE TREATMENT | PALBOCICLIB | P16(INK4A) EXPRESSION | ONCOLOGY | CRYSTAL-STRUCTURE | SENSITIVITY | COMBINATION | ABERRATIONS | CANCER
Journal Article
Journal Article
Endocrine Reviews, ISSN 0163-769X, 02/2010, Volume 31, Issue 1, pp. 137 - 137
Journal Article
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