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1. Full Text Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial
by Migden, Michael R, Dr and Guminski, Alexander, PhD and Gutzmer, Ralf, Prof and Dirix, Luc, MD and Lewis, Karl D, MD and Combemale, Patrick, MD and Herd, Robert M, MD and Kudchadkar, Ragini, MD and Trefzer, Uwe, Prof and Gogov, Sven, MD and Pallaud, Celine, PhD and Yi, Tingting, PhD and Mone, Manisha, PhD and Kaatz, Martin, MD and Loquai, Carmen, MD and Stratigos, Alexander J, Prof and Schulze, Hans-Joachim, MD and Plummer, Ruth, Prof and Chang, Anne Lynn S, MD and Cornélis, Frank, MD and Lear, John T, MD and Sellami, Dalila, MD and Dummer, Reinhard, Prof
The lancet oncology, ISSN 1470-2045, 2015, Volume 16, Issue 6, pp. 716 - 728
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasm Recurrence, Local - radiotherapy | Skin Neoplasms - drug therapy | Skin Neoplasms - radiotherapy | Humans | Middle Aged | Biphenyl Compounds - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Neoplasm Recurrence, Local - surgery | Neoplasm Recurrence, Local - pathology | Neoplasm Metastasis | Pyridines - adverse effects | Aged, 80 and over | Adult | Female | Skin Neoplasms - surgery | Skin Neoplasms - pathology | Carcinoma, Basal Cell - radiotherapy | Pyridines - administration & dosage | Double-Blind Method | Kaplan-Meier Estimate | Treatment Outcome | Carcinoma, Basal Cell - pathology | Disease-Free Survival | Carcinoma, Basal Cell - surgery | Biphenyl Compounds - administration & dosage | Carcinoma, Basal Cell - drug therapy | Aged | Medical colleges | Care and treatment | Basal cell carcinoma | Surgical clinics | Clinical trials | Skin | Metastasis | Index Medicus
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2. Full Text Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial
by Cameron, David, Prof and Brown, Julia, Prof and Dent, Rebecca, MD and Jackisch, Christian, MD and Mackey, John, Prof and Pivot, Xavier, MD and Steger, Guenther G, Prof and Suter, Thomas M, Prof and Toi, Masakazu, Prof and Parmar, Mahesh, DPhil and Laeufle, Rita, MD and Im, Young-Hyuck, MD and Romieu, Gilles, MD and Harvey, Vernon, MD and Lipatov, Oleg, MD and Pienkowski, Tadeusz, MD and Cottu, Paul, MD and Chan, Arlene, Prof and Im, Seock-Ah, Prof and Hall, Peter S, PhD and Bubuteishvili-Pacaud, Lida, MD and Henschel, Volkmar, PhD and Deurloo, Regula J, PhD and Pallaud, Celine, PhD and Bell, Richard, Prof
The lancet oncology, ISSN 1470-2045, 2013, Volume 14, Issue 10, pp. 933 - 942
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Antibodies, Monoclonal, Humanized - adverse effects | Humans | Middle Aged | Vascular Endothelial Growth Factor A - blood | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Vascular Endothelial Growth Factor Receptor-2 - blood | Receptors, Estrogen - analysis | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Breast Neoplasms - drug therapy | Bevacizumab | Receptors, Progesterone - analysis | Breast Neoplasms - chemistry | Antibodies, Monoclonal, Humanized - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Adult | Breast Neoplasms - mortality | Female | Aged | Chemotherapy, Adjuvant | Receptor, ErbB-2 - analysis | Breast cancer | Adjuvant treatment | Cancer | Index Medicus
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3. Full Text The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell carcinoma
by Dummer, Reinhard, MD and Guminski, Alexander, MD, PhD and Gutzmer, Ralf, MD and Dirix, Luc, MD and Lewis, Karl D., MD and Combemale, Patrick, MD and Herd, Robert M., MD and Kaatz, Martin, MD and Loquai, Carmen, MD and Stratigos, Alexander J., MD and Schulze, Hans-Joachim, MD and Plummer, Ruth, MD and Gogov, Sven, MD and Pallaud, Celine, PhD and Yi, Tingting, PhD and Mone, Manisha, PhD and Chang, Anne Lynn S., MD and Cornélis, Frank, MD and Kudchadkar, Ragini, MD and Trefzer, Uwe, MD and Lear, John T., MD and Sellami, Dalila, MD and Migden, Michael R., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 75, Issue 1, pp. 113 - 125.e5
Dermatology | Basal Cell Carcinoma Outcomes with LDE225 Treatment study | hedgehog pathway inhibitor | sonidegib | locally advanced basal cell carcinoma | metastatic basal cell carcinoma | advanced basal cell carcinoma | Locally advanced basal cell carcinoma | Advanced basal cell carcinoma | Metastatic basal cell carcinoma | Sonidegib | Hedgehog pathway inhibitor | Life Sciences & Biomedicine | Science & Technology | Skin Neoplasms - drug therapy | Humans | Middle Aged | Carcinoma, Basal Cell - secondary | Biphenyl Compounds - adverse effects | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Biphenyl Compounds - therapeutic use | Young Adult | Pyridines - adverse effects | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Smoothened Receptor - antagonists & inhibitors | Pyridines - therapeutic use | Skin Neoplasms - pathology | Pyridines - administration & dosage | Double-Blind Method | Survival Rate | Disease Progression | Biphenyl Compounds - administration & dosage | Carcinoma, Basal Cell - drug therapy | Aged | Medical research | Care and treatment | Basal cell carcinoma | Analysis | Patient outcomes | Corn | Medicine, Experimental | Skin | Metastasis | Drug therapy | Cancer | Index Medicus
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