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1. Full Text Guidelines of care for the management of atopic dermatitis
by Sidbury, Robert, MD and Davis, Dawn M., MD and Cohen, David E., MD and Cordoro, Kelly M., MD and Berger, Timothy G., MD and Bergman, James N., MD and Chamlin, Sarah L., MD, MSCI and Cooper, Kevin D., MD and Feldman, Steven R., MD, PhD and Hanifin, Jon M., MD and Krol, Alfons, MD and Margolis, David J., MD, PhD and Paller, Amy S., MD and Schwarzenberger, Kathryn, MD and Silverman, Robert A., MD and Simpson, Eric L., MD and Tom, Wynnis L., MD and Williams, Hywel C., DSc and Elmets, Craig A., MD and Block, Julie, BA and Harrod, Christopher G., MS and Begolka, Wendy Smith, MBS and Eichenfield, Lawrence F., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2014, Volume 71, Issue 2, pp. 327 - 349
Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important... 
Dermatology | interferon gamma | oral antihistamines | oral steroids | photochemotherapy | cyclosporin A | atopic dermatitis | azathioprine | methotrexate | mycophenolate mofetil | phototherapy | systemic therapy | oral antimicrobials | ULTRAVIOLET-B PHOTOTHERAPY | EXTRACORPOREAL PHOTOCHEMOTHERAPY | UVB PHOTOTHERAPY | RANDOMIZED CONTROLLED-TRIAL | DERMATOLOGY | PSORALEN PHOTOCHEMOTHERAPY | DOUBLE-BLIND | THIOPURINE METHYLTRANSFERASE | STAPHYLOCOCCUS-AUREUS | LONG-TERM TREATMENT | MYCOPHENOLATE-MOFETIL | Medical colleges | Antihistamines | Hospitals | Atopic dermatitis | Practice guidelines (Medicine) | Anti-infective agents | Phototherapy
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2. Full Text Prescribing practices for systemic agents in the treatment of severe pediatric atopic dermatitis in the US and Canada: The PeDRA TREAT survey
by Totri, Christine R., MD, MAS and Eichenfield, Lawrence F., MD and Logan, Kirsty, PhD and Proudfoot, Laura, MD, PhD and Schmitt, Jochen, MD, MPH and Lara-Corrales, Irene, MD, MSc and Sugarman, Jeffrey, MD, PhD and Tom, Wynnis, MD and Siegfried, Elaine, MD and Cordoro, Kelly, MD and Paller, Amy S., MD, MS and Flohr, Carsten, MD, PhD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 76, Issue 2, pp. 281 - 285
Background There is a paucity of literature to direct physicians in the prescribing of immunomodulators for patients with severe atopic dermatitis (AD).... 
Dermatology | cyclosporine | oral steroids | atopic dermatitis | azathioprine | methotrexate | mycophenolate mofetil | oral antimicrobials | TRIAL | ECZEMA | CHILDREN | DERMATOLOGY | Severity of Illness Index | Pediatrics | Azathioprine - therapeutic use | United States | Humans | Middle Aged | Male | Practice Patterns, Physicians | Methotrexate - therapeutic use | Drug Prescriptions - standards | Canada | Cyclosporine - therapeutic use | Dermatitis, Atopic - drug therapy | Mycophenolic Acid - therapeutic use | Adult | Female | Child | Health Care Surveys | Surveys | Medical colleges | Care and treatment | Prescription writing | Atopic dermatitis | Children's hospitals | Skin | Children | Health aspects | Anti-infective agents | Mycophenolate mofetil | Index Medicus
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3. Full Text Pediatric morphea (localized scleroderma): Review of 136 patients
by Christen-Zaech, Stéphanie, MD and Hakim, Miriam D., MD and Afsar, F. Sule, MD and Paller, Amy S., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2008, Volume 59, Issue 3, pp. 385 - 396
Background Morphea is an autoimmune inflammatory sclerosing disorder that may cause permanent functional disability and disfigurement. Objectives We sought to... 
Dermatology | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ABNORMALITIES | DISEASE | OVERLAP SYNDROMES | METHOTREXATE | SCLEROSIS | LINEAR SCLERODERMA | CHILDHOOD | CHILDREN | FEATURES | DERMATOLOGY | Scleroderma, Localized - drug therapy | Prevalence | Scleroderma, Localized - complications | Humans | Risk Factors | Autoimmune Diseases - complications | Child, Preschool | European Continental Ancestry Group | Infant | Male | Scleroderma, Localized - diagnosis | Dermatologic Agents - therapeutic use | Methotrexate - therapeutic use | Scleroderma, Localized - ethnology | Antibodies, Antinuclear - blood | Scleroderma, Systemic - complications | Adolescent | Age of Onset | Sex Factors | Female | Retrospective Studies | Child | Skin - pathology | Pediatrics | Autoantibodies
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4. Full Text Long-term safety and efficacy of etanercept in children and adolescents with plaque psoriasis
by Paller, Amy S., MD and Siegfried, Elaine C., MD and Pariser, David M., MD and Rice, Kara Creamer, MS and Trivedi, Mona, MD and Iles, Jan, MD and Collier, David H., MD and Kricorian, Greg, MD and Langley, Richard G., MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2015, Volume 74, Issue 2, pp. 280 - 287.e3
Background There are no systemic therapies approved in the United States to treat pediatric psoriasis. Objective We sought to evaluate long-term safety and... 
Dermatology | plaque psoriasis | pediatric population | etanercept | open-label | long-term safety | PEDIATRIC PSORIASIS | JUVENILE IDIOPATHIC ARTHRITIS | OVERWEIGHT | QUALITY-OF-LIFE | ADVERSE EVENTS | DERMATOLOGY | Severity of Illness Index | Etanercept - adverse effects | Psoriasis - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Nasopharyngitis - chemically induced | Child, Preschool | Male | Cellulitis - chemically induced | Time Factors | Adolescent | Respiratory Tract Infections - chemically induced | Female | Immunosuppressive Agents - adverse effects | Child | Headache - chemically induced | Etanercept - therapeutic use
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5. Full Text Alterations in B-cell subsets in pediatric patients with early atopic dermatitis
by Czarnowicki, Tali, MD, MSc and Esaki, Hitokazu, MD and Gonzalez, Juana, PhD and Renert-Yuval, Yael, MD and Brunner, Patrick, MD and Oliva, Margeaux, BA and Estrada, Yeriel, BSc and Xu, Hui, MSc and Zheng, Xiuzhong, MSc and Talasila, Sreya, MD and Haugh, Isabel, MD and Huynh, Thy, MD and Lyon, Sarah, BA and Tran, Gary, BA and Sampson, Hugh, MD and Suárez-Fariñas, Mayte, PhD and Krueger, James G., MD, PhD and Guttman-Yassky, Emma, MD, PhD and Paller, Amy S., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 140, Issue 1, pp. 134 - 144.e9
Background B cells undergo maturation and class-switching in response to antigen exposure and T-cell help. Early B-cell differentiation has not been defined in... 
Allergy and Immunology | B cells | T cells | allergen-specific IgE | Atopic dermatitis | atopic march | IMMUNE-RESPONSE | SYSTEMIC-LUPUS-ERYTHEMATOSUS | DENDRITIC CELLS | FOOD ALLERGY | IFN-GAMMA | CD40 LIGAND | PERIPHERAL-BLOOD | IMMUNOLOGY | REFERENCE VALUES | ALLERGY | HUMAN IGE | T-CELLS | Skin - cytology | Humans | Middle Aged | Child, Preschool | Infant | Male | Immunoglobulin E - blood | Aging - immunology | Immunoglobulin E - immunology | Allergens - immunology | Dermatitis, Atopic - immunology | Adult | B-Lymphocyte Subsets - immunology | Female | T-Lymphocytes - immunology | Dermatitis, Atopic - blood | Skin - immunology | Pediatrics | Food allergy | Medical colleges | Analysis | Skin | Children | Cell differentiation | Health aspects | Antigens | CD27 antigen | Allergens | Flow cytometry | Differentiation (biology) | Immunoglobulin E | Lymphocytes T | Immunoglobulin D | Dermatitis | Gating systems | Lymphocytes | CD38 antigen | Skin diseases | Lesions | Gating | Age | Food allergies | Immunological memory | Memory cells | Immunoglobulins | CD19 antigen | Maturation | Color | CD3 antigen | T cell receptors | Patients | Switching | Lymphocytes B | Correlation analysis | CD20 antigen | Ligands | Adults | Silicon germanides
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6. Full Text An IL-17–dominant immune profile is shared across the major orphan forms of ichthyosis
by Paller, Amy S., MD, MS and Renert-Yuval, Yael, MD and Suprun, Maria, MPH and Esaki, Hitokazu, MD and Oliva, Margeaux, BA and Huynh, Thy Nhat, MD and Ungar, Benjamin, BA and Kunjravia, Norma, MD and Friedland, Rivka, MD and Peng, Xiangyu, MSc and Zheng, Xiuzhong, MSc and Estrada, Yeriel D., BSc and Krueger, James G., MD, PhD and Choate, Keith A and Suárez-Fariñas, Mayte, PhD and Guttman-Yassky, Emma, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 1, pp. 152 - 165
Background The ichthyoses are rare genetic disorders associated with generalized scaling, erythema, and epidermal barrier impairment. Pathogenesis-based... 
Allergy and Immunology | Netherton syndrome | TNF-α | inflammation | IL-17 | skin | Epidermis | congenital ichthyosiform erythroderma | epidermolytic ichthyosis | ichthyosis | lamellar ichthyosis | autosomal recessive congenital ichthyosis | TO-SEVERE PSORIASIS | CONTROLLED-TRIAL | TNF-alpha | BARRIER FUNCTION | STRATUM-CORNEUM | MONOCLONAL-ANTIBODY | IMMUNOLOGY | COMEL-NETHERTON-SYNDROME | SEVERE ATOPIC-DERMATITIS | ALLERGY | RECESSIVE CONGENITAL ICHTHYOSIS | PERMEABILITY BARRIER | Psoriasis - immunology | Severity of Illness Index | Dermatitis, Atopic - genetics | Gene Expression | Humans | Middle Aged | Interleukin-17 - immunology | Interleukin-17 - genetics | Male | RNA, Messenger - metabolism | Interleukin-23 - immunology | Ichthyosis - immunology | Interleukin-23 - genetics | Young Adult | Psoriasis - genetics | Adolescent | Dermatitis, Atopic - immunology | Ichthyosis - genetics | Adult | Female | Aged | Child | Skin - immunology | Medical colleges | Skin diseases | Skin | Orphans | Demographics | Congenital diseases | Baldness | Cytokines | Psoriasis | Inflammation | Mutation | Family medical history | Pruritus | Age
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7. Full Text Phenotype of atopic dermatitis subjects with a history of eczema herpeticum
by Beck, Lisa A., MD and Boguniewicz, Mark, MD and Hata, Tissa, MD and Schneider, Lynda C., MD and Hanifin, Jon, MD and Gallo, Rich, MD, PhD and Paller, Amy S., MD and Lieff, Susi, PhD and Reese, Jamie, BS and Zaccaro, Daniel, MS and Milgrom, Henry, MD and Barnes, Kathleen C., PhD and Leung, Donald Y.M., MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 2, pp. 260 - 269.e7
Background A subset of subjects with atopic dermatitis (AD) are susceptible to serious infections with herpes simplex virus, called eczema herpeticum, or... 
Allergy and Immunology | herpes simplex virus | eczema vaccinatum | Atopic dermatitis | biomarkers | eczema herpeticum | Staphylococcus aureus | FOOD ALLERGY | INNATE IMMUNE-RESPONSE | ANTIMICROBIAL PEPTIDES | VACCINIA VIRUS | IMMUNOLOGY | ACTIVATION-REGULATED CHEMOKINE | ALLERGY | TH2 CYTOKINES | DISEASE | SERUM THYMUS | SKIN | EXPRESSION | Kaposi Varicelliform Eruption - immunology | Humans | Middle Aged | Child, Preschool | Infant | Male | Th2 Cells - immunology | Antibodies, Viral - blood | Immunoglobulin E - blood | Young Adult | Kaposi Varicelliform Eruption - virology | Allergens - immunology | Dermatitis, Atopic - immunology | Aged, 80 and over | Adult | Female | Child | Chemokine CCL27 - metabolism | Dermatitis, Atopic - virology | Dermatitis, Atopic - complications | Kaposi Varicelliform Eruption - etiology | Herpesvirus 2, Human | Herpesvirus 1, Human | Interferon-beta - metabolism | Adolescent | Aged | Chemokine CCL17 - metabolism | Chemokine CXCL10 - metabolism | Medical colleges | Medical examination | Vaccination | Eczema | Staphylococcus aureus infections | Genetic aspects | T cells | Health aspects | Blood | Smallpox | Genotype & phenotype | Immunization | Disease | Hispanic Americans | African Americans | Biomarkers | Viral infections | staphylococcus aureus
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8. Full Text Bacterial colonization, overgrowth, and superinfection in atopic dermatitis
by Rangel, Stephanie M., PhD and Paller, Amy S., MD
Clinics in Dermatology, ISSN 0738-081X, 2018, Volume 36, Issue 5, pp. 641 - 647
Abstract Staphylococcus aureus infection is a major burden for individuals with moderate-to-severe atopic dermatitis and a known inducer of disease... 
Dermatology | UNITED-STATES | ECZEMA PREVALENCE | VITAMIN-D | BLEACH BATHS | SKIN MICROBIOME | INTESTINAL MICROBIOTA | DISEASE | STAPHYLOCOCCUS-AUREUS COLONIZATION | SEVERITY | CHILDREN | DERMATOLOGY | Symbiosis | Skin - microbiology | Humans | Dermatitis, Atopic - microbiology | Immunity, Innate | Anti-Bacterial Agents - therapeutic use | Microbiota | Staphylococcal Skin Infections - drug therapy | Superinfection - immunology | Disease Susceptibility - immunology | Staphylococcal Skin Infections - immunology | Dermatitis, Atopic - immunology | Staphylococcus aureus | Medical colleges | Atopic dermatitis | Staphylococcus aureus infections | Skin care products | Disease susceptibility | Skin | Antibacterial agents
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9. Full Text Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States
by Hsu, Derek Y., BA and Brieva, Joaquin, MD and Silverberg, Nanette B., MD and Paller, Amy S., MD, MS and Silverberg, Jonathan I., MD, PhD, MPH
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2016, Volume 76, Issue 5, pp. 811 - 817.e4
Background Little is known about the epidemiology of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in children. Objective We sought to... 
Dermatology | epidemiology | Stevens-Johnson syndrome | hospitalization | children | burden of disease | pediatric | toxic epidermal necrolysis | ERYTHEMA MULTIFORME | GERMANY | DISEASE | OF-THE-LITERATURE | DERMATOLOGY | United States - epidemiology | Age Factors | Cross-Sectional Studies | Comorbidity | Humans | Risk Factors | Sepsis - epidemiology | Child, Preschool | Infant | Stevens-Johnson Syndrome - mortality | Renal Insufficiency - epidemiology | Stevens-Johnson Syndrome - economics | Epilepsy - epidemiology | Incidence | Stevens-Johnson Syndrome - epidemiology | Health Care Costs - statistics & numerical data | Adolescent | Child | Infant, Newborn | Length of Stay - statistics & numerical data | Neoplasms - epidemiology | Pediatrics | Medical colleges | Medicine, Preventive | Epidemiology | Preventive health services | Bacterial infections | Analysis | Mortality | Children | Health aspects | Diseases | Index Medicus
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10. Full Text A systematic review of topical corticosteroid withdrawal (“steroid addiction”) in patients with atopic dermatitis and other dermatoses
by Hajar, Tamar, MD and Leshem, Yael A., MD and Hanifin, Jon M., MD and Nedorost, Susan T., MD and Lio, Peter A., MD and Paller, Amy S., MD and Block, Julie, BA and Simpson, Eric L., MD, MCR and Natl Eczema Assoc Task Force and the National Eczema Association Task Force
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2014, Volume 72, Issue 3, pp. 541 - 549.e2
Background The National Eczema Association has received increasing numbers of patient inquiries regarding “steroid addiction syndrome,” coinciding with the... 
Dermatology | pruritus | topical corticosteroid withdrawal | topical corticosteroids | atopic dermatitis | side effects | red face | steroid addiction | PERIORAL DERMATITIS | MANAGEMENT | GUIDELINES | CARE | CHILDREN | DERMATOLOGY | ROSACEA-LIKE DERMATITIS | THERAPIES | QUALITY-OF-LIFE | FACE | OINTMENT | Adrenal Cortex Hormones - adverse effects | Dermatitis, Atopic - drug therapy | Dermatologic Agents - administration & dosage | Humans | Skin Diseases - drug therapy | Substance Withdrawal Syndrome - therapy | Administration, Topical | Dermatologic Agents - adverse effects | Substance Withdrawal Syndrome - diagnosis | Adrenal Cortex Hormones - administration & dosage | Drug abuse | Care and treatment | Corticosteroids | Atopic dermatitis
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11. Full Text Nocturnal eczema: Review of sleep and circadian rhythms in children with atopic dermatitis and future research directions
by Fishbein, Anna B., MD, MSci and Vitaterna, Olivia and Haugh, Isabel M., MB, BAO, BCh and Bavishi, Aakash A., BA and Zee, Phyllis C., MD, PhD and Turek, Fred W., PhD and Sheldon, Stephen H., DO and Silverberg, Jonathan I., MD, PhD, MPH and Paller, Amy S., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 5, pp. 1170 - 1177
Children with atopic dermatitis (AD) experience significant sleep disruption, and clinically, the disease is noted to worsen in a circadian manner at night.... 
Allergy and Immunology | sleep | eczema | sleep disturbance | circadian rhythms | Atopic dermatitis | QUALITY | MELATONIN | EFFICACY | DISEASE SEVERITY | ADULTS | IMMUNOLOGY | DISTURBANCE | ALLERGY | PEDIATRIC-PATIENTS | SKIN | CLOCK | LIFE | Sleep - immunology | Animals | Eczema - immunology | Humans | Dermatitis, Atopic - immunology | Circadian Rhythm - immunology | Child | Sleep Wake Disorders - immunology | Circadian rhythms | Sleep disorders | Medical colleges | Sleep | Eczema | Children | Health aspects | Neurophysiology | Circadian rhythm | Insomnia | Dermatitis | Sleep deprivation | Quality of life
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