2015, ISBN 1498500072, xxii, 278
Book
Cytokine, ISSN 1043-4666, 09/2015, Volume 75, Issue 1, pp. 79 - 88
The Th2 cytokines, interleukin (IL)-4 and -13, are structurally and functionally related. They regulate immune responses and the immune microenvironment, not...
Interleukin-4 | Receptor-targeted cancer therapy | Interleukin-4 receptor | Interleukin-13 receptor | Interleukin-13 | Neoplasms - metabolism | Immunotherapy - methods | Interleukin-13 Receptor alpha2 Subunit - metabolism | Interleukin-4 Receptor alpha Subunit - metabolism | Cell Proliferation | Cell Survival | Humans | Gene Expression Regulation, Neoplastic | Polyethylene Glycols - chemistry | Antineoplastic Agents - therapeutic use | Doxorubicin - chemistry | Receptors, Interleukin-13 - metabolism | Cell Adhesion | Neoplasm Metastasis | Animals | Doxorubicin - analogs & derivatives | Biomarkers, Tumor - metabolism | Antigens - immunology | Immunotoxins - chemistry | Mice | Antibodies, Monoclonal - immunology | Disease Models, Animal | Antimitotic agents | Care and treatment | Interleukins | Physiological aspects | Cellular signal transduction | Antibody-toxin conjugates | Antineoplastic agents | Health aspects | Cancer | Index Medicus
Interleukin-4 | Receptor-targeted cancer therapy | Interleukin-4 receptor | Interleukin-13 receptor | Interleukin-13 | Neoplasms - metabolism | Immunotherapy - methods | Interleukin-13 Receptor alpha2 Subunit - metabolism | Interleukin-4 Receptor alpha Subunit - metabolism | Cell Proliferation | Cell Survival | Humans | Gene Expression Regulation, Neoplastic | Polyethylene Glycols - chemistry | Antineoplastic Agents - therapeutic use | Doxorubicin - chemistry | Receptors, Interleukin-13 - metabolism | Cell Adhesion | Neoplasm Metastasis | Animals | Doxorubicin - analogs & derivatives | Biomarkers, Tumor - metabolism | Antigens - immunology | Immunotoxins - chemistry | Mice | Antibodies, Monoclonal - immunology | Disease Models, Animal | Antimitotic agents | Care and treatment | Interleukins | Physiological aspects | Cellular signal transduction | Antibody-toxin conjugates | Antineoplastic agents | Health aspects | Cancer | Index Medicus
Journal Article
Neuro-Oncology, ISSN 1522-8517, 8/2010, Volume 12, Issue 8, pp. 871 - 881
Convection-enhanced delivery (CED) of cintredekin besudotox (CB) was compared with Gliadel wafers (GW) in adult patients with glioblastoma multiforme (GBM) at...
Gliadel wafers | Cintredekin besudotox | Convection-enhanced delivery | Glioblastoma multiforme | IL13-PE38QQR | Humans | Middle Aged | Interleukin-13 - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Antineoplastic Agents - administration & dosage | Decanoic Acids - adverse effects | Convection | Exotoxins - adverse effects | Young Adult | Exotoxins - administration & dosage | Polyesters - administration & dosage | Adult | Female | Brain Neoplasms - mortality | Catheters, Indwelling | Drug Administration Routes | Interleukin-13 - administration & dosage | Polyesters - adverse effects | Carmustine | Kaplan-Meier Estimate | Decanoic Acids - administration & dosage | Brain Neoplasms - drug therapy | Magnetic Resonance Imaging | Adolescent | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | cintredekin besudotox | glioblastoma multiforme | Clinical Investigations | convection-enhanced delivery
Gliadel wafers | Cintredekin besudotox | Convection-enhanced delivery | Glioblastoma multiforme | IL13-PE38QQR | Humans | Middle Aged | Interleukin-13 - adverse effects | Neoplasm Recurrence, Local - drug therapy | Male | Antineoplastic Agents - administration & dosage | Decanoic Acids - adverse effects | Convection | Exotoxins - adverse effects | Young Adult | Exotoxins - administration & dosage | Polyesters - administration & dosage | Adult | Female | Brain Neoplasms - mortality | Catheters, Indwelling | Drug Administration Routes | Interleukin-13 - administration & dosage | Polyesters - adverse effects | Carmustine | Kaplan-Meier Estimate | Decanoic Acids - administration & dosage | Brain Neoplasms - drug therapy | Magnetic Resonance Imaging | Adolescent | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | cintredekin besudotox | glioblastoma multiforme | Clinical Investigations | convection-enhanced delivery
Journal Article
Journal of the American Medical Directors Association, ISSN 1525-8610, 04/2019, Volume 20, Issue 4, pp. 462 - 469
To understand physical therapy (PT) and occupational therapy (OT) staffing levels in nursing homes and to examine their relationship with quality of care....
Therapy staff | nursing home policy | Medicare and Medicaid | quality of care | non-nursing staff | SYSTEM | MEDICARE PROSPECTIVE-PAYMENT | FACILITIES | RISK | GERIATRICS & GERONTOLOGY | IMPACT | REHABILITATION | OUTCOMES | FALL | Medical policy | Nursing homes | Care and treatment | Activities of daily living | Medicare | Therapeutics, Physiological | Information management | Patients | Analysis | Medical care | Occupational therapy | Medicaid | Physical therapy | Quality management
Therapy staff | nursing home policy | Medicare and Medicaid | quality of care | non-nursing staff | SYSTEM | MEDICARE PROSPECTIVE-PAYMENT | FACILITIES | RISK | GERIATRICS & GERONTOLOGY | IMPACT | REHABILITATION | OUTCOMES | FALL | Medical policy | Nursing homes | Care and treatment | Activities of daily living | Medicare | Therapeutics, Physiological | Information management | Patients | Analysis | Medical care | Occupational therapy | Medicaid | Physical therapy | Quality management
Journal Article
American Journal of Occupational Therapy, ISSN 0272-9490, 01/2015, Volume 69, Issue 1, pp. 16 - 22
The authors set forth a foundation on which to build further dialogue and evidence to highlight occupational therapy’s distinctive contribution, significance,...
Patient outcome assessment | Occupational therapy | Value-based purchasing | Delivery of health care | Quality of health care | FALLS | quality of health care | PRIMARY-CARE | VULNERABLE ELDERS | REHABILITATION | value-based purchasing | delivery of health care | INTERVENTION | occupational therapy | patient outcome assessment | URINARY-INCONTINENCE | Occupational Therapy - trends | United States | Humans | Health Care Reform - trends | Cooperative Behavior | Cost-Benefit Analysis - trends | Patient Protection and Affordable Care Act - economics | Quality Assurance, Health Care - economics | Patient Protection and Affordable Care Act - trends | Health Care Reform - economics | Forecasting | Quality Indicators, Health Care - economics | Quality Improvement - trends | Interdisciplinary Communication | Delivery of Health Care - economics | Quality Improvement - economics | Occupational Therapy - economics | Quality Assurance, Health Care - trends | Quality Indicators, Health Care - trends | Delivery of Health Care - trends | Medical policy | Influence | Standards | Health Policy s
Patient outcome assessment | Occupational therapy | Value-based purchasing | Delivery of health care | Quality of health care | FALLS | quality of health care | PRIMARY-CARE | VULNERABLE ELDERS | REHABILITATION | value-based purchasing | delivery of health care | INTERVENTION | occupational therapy | patient outcome assessment | URINARY-INCONTINENCE | Occupational Therapy - trends | United States | Humans | Health Care Reform - trends | Cooperative Behavior | Cost-Benefit Analysis - trends | Patient Protection and Affordable Care Act - economics | Quality Assurance, Health Care - economics | Patient Protection and Affordable Care Act - trends | Health Care Reform - economics | Forecasting | Quality Indicators, Health Care - economics | Quality Improvement - trends | Interdisciplinary Communication | Delivery of Health Care - economics | Quality Improvement - economics | Occupational Therapy - economics | Quality Assurance, Health Care - trends | Quality Indicators, Health Care - trends | Delivery of Health Care - trends | Medical policy | Influence | Standards | Health Policy s
Journal Article
AMERICAN JOURNAL OF OCCUPATIONAL THERAPY, ISSN 0272-9490, 01/2019, Volume 73, Issue 1, p. 7301205140p1
Readmissions to health care facilities are undesirable outcomes that indicate the quality of the care transitions. Although there is a growing evidence-base...
REDUCE HOSPITAL READMISSIONS | VISITS | OLDER-ADULTS | HIGH-RISK | HEART-FAILURE | REHABILITATION | PLANNING INTERVENTION | RANDOMIZED CONTROLLED-TRIAL | QUALITY-OF-LIFE | HOME | PROGRAM | Subacute Care - organization & administration | Delivery of Health Care - organization & administration | Humans | Patient Transfer | Patient Discharge | Transitional care | Medical care | Rehabilitation | Management | Methods | Quality management | Intervention | Drugs | Coaching | Transitions | Health services | Communities | Subacute care | Clinical research | Patients | Clinical outcomes | Selfmanagement | Acute services | Quality of care
REDUCE HOSPITAL READMISSIONS | VISITS | OLDER-ADULTS | HIGH-RISK | HEART-FAILURE | REHABILITATION | PLANNING INTERVENTION | RANDOMIZED CONTROLLED-TRIAL | QUALITY-OF-LIFE | HOME | PROGRAM | Subacute Care - organization & administration | Delivery of Health Care - organization & administration | Humans | Patient Transfer | Patient Discharge | Transitional care | Medical care | Rehabilitation | Management | Methods | Quality management | Intervention | Drugs | Coaching | Transitions | Health services | Communities | Subacute care | Clinical research | Patients | Clinical outcomes | Selfmanagement | Acute services | Quality of care
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10063 - 9
Glioblastoma (GBM) is a heterogeneous and lethal brain cancer. These tumors are followed using magnetic resonance imaging (MRI), which is unable to precisely...
INVASION | PROLIFERATION | KINETICS | MULTIDISCIPLINARY SCIENCES | GROWTH | Learning | Neuroimaging | Learning algorithms | Statistical analysis | Nuclear magnetic resonance--NMR | Magnetic resonance imaging | Brain tumors | Surgery | Machine learning | Glioblastoma | Artificial intelligence | Cell density
INVASION | PROLIFERATION | KINETICS | MULTIDISCIPLINARY SCIENCES | GROWTH | Learning | Neuroimaging | Learning algorithms | Statistical analysis | Nuclear magnetic resonance--NMR | Magnetic resonance imaging | Brain tumors | Surgery | Machine learning | Glioblastoma | Artificial intelligence | Cell density
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 1928 - 1928
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi172 - vi172
Abstract There have been increasing efforts to standardize MRI scanning protocols for both routine and clinical trial imaging of glioma. The recent BTIP...
Journal Article
Cancer Medicine, ISSN 2045-7634, 12/2014, Volume 3, Issue 6, pp. 1615 - 1628
Previously, we have demonstrated that interleukin‐4 receptor α (IL‐4Rα) is overexpressed on a variety of human cancers and can serve as target for IL‐4...
Biomarker | IL‐4Rα | grade and clinical stage | tumor aggressiveness | bladder cancer–associated protein | Tumor aggressiveness | Grade and clinical stage | Bladder cancer-associated protein | IL-4Rα | CD4(+) T-CELLS | IL-4R alpha | bladder cancer-associated protein | RENAL-CELL CARCINOMA | CYTOTOXIN THERAPY | MALIGNANT GLIOMA | IN-VITRO | PULMONARY METASTASIS | ONCOLOGY | HUMAN PLEURAL MESOTHELIOMA | ANTITUMOR IMMUNITY | PSEUDOMONAS EXOTOXIN | TUMOR-GROWTH | Human Umbilical Vein Endothelial Cells | Immunohistochemistry | Tissue Array Analysis | Humans | Middle Aged | Interleukin-4 Receptor alpha Subunit - biosynthesis | Interleukin-4 Receptor alpha Subunit - genetics | Animals | Heterografts | Neoplasm Grading | Urinary Bladder Neoplasms - genetics | Mice, Nude | Urinary Bladder Neoplasms - pathology | Cell Line, Tumor | Adult | Female | Aged | Mice | Neoplasm Staging | Real-Time Polymerase Chain Reaction | Urinary Bladder Neoplasms - metabolism | Interleukins | Bladder cancer | Analysis | Cell proliferation | Statistical analysis | Cytokines | Immunodeficiency | Colorectal cancer | Melanoma | mRNA | Metastasis | Regression analysis | Tumor cell lines | Cancer therapies | Skin cancer | Signal transduction | Cell growth | Biopsy | Lymphocytes | Medical prognosis | Cell lines | Xenografts | Prostate | Umbilical vein | Tumors | Index Medicus | Cancer Biology
Biomarker | IL‐4Rα | grade and clinical stage | tumor aggressiveness | bladder cancer–associated protein | Tumor aggressiveness | Grade and clinical stage | Bladder cancer-associated protein | IL-4Rα | CD4(+) T-CELLS | IL-4R alpha | bladder cancer-associated protein | RENAL-CELL CARCINOMA | CYTOTOXIN THERAPY | MALIGNANT GLIOMA | IN-VITRO | PULMONARY METASTASIS | ONCOLOGY | HUMAN PLEURAL MESOTHELIOMA | ANTITUMOR IMMUNITY | PSEUDOMONAS EXOTOXIN | TUMOR-GROWTH | Human Umbilical Vein Endothelial Cells | Immunohistochemistry | Tissue Array Analysis | Humans | Middle Aged | Interleukin-4 Receptor alpha Subunit - biosynthesis | Interleukin-4 Receptor alpha Subunit - genetics | Animals | Heterografts | Neoplasm Grading | Urinary Bladder Neoplasms - genetics | Mice, Nude | Urinary Bladder Neoplasms - pathology | Cell Line, Tumor | Adult | Female | Aged | Mice | Neoplasm Staging | Real-Time Polymerase Chain Reaction | Urinary Bladder Neoplasms - metabolism | Interleukins | Bladder cancer | Analysis | Cell proliferation | Statistical analysis | Cytokines | Immunodeficiency | Colorectal cancer | Melanoma | mRNA | Metastasis | Regression analysis | Tumor cell lines | Cancer therapies | Skin cancer | Signal transduction | Cell growth | Biopsy | Lymphocytes | Medical prognosis | Cell lines | Xenografts | Prostate | Umbilical vein | Tumors | Index Medicus | Cancer Biology
Journal Article
1992, Illinois Natural History Survey bulletin, ISBN 2173336880, Volume 34, art. 6, 537-549
Book
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 5, p. e0217131
Pyruvate kinase M2 (PKM2) is an alternatively spliced variant, which mediates the conversion of glucose to lactate in cancer cells under normoxic conditions,...
Immunohistochemistry | Enzymes | RNA | Lung cancer, Non-small cell | Health aspects | Analysis | Therapy | Biotechnology | Alternative splicing | Enzyme activity | Immunocytochemistry | Xenotransplantation | Lung cancer | Colorectal cancer | Staining | Pyruvic acid | mRNA | Kinases | Cancer therapies | Proteins | Signal transduction | Cell growth | Immunology | Epidermal growth factor | Enzymatic activity | Xenografts | Gallbladder | Food | Medical research | Pyruvate kinase | Non-small cell lung carcinoma | Tumor cell lines | Metabolism | Gene expression | Chemotherapy | Medical prognosis | Cell lines | Biomarkers | Hypoxia | Lactic acid | Viability | Cytoplasm | Tumors | Apoptosis
Immunohistochemistry | Enzymes | RNA | Lung cancer, Non-small cell | Health aspects | Analysis | Therapy | Biotechnology | Alternative splicing | Enzyme activity | Immunocytochemistry | Xenotransplantation | Lung cancer | Colorectal cancer | Staining | Pyruvic acid | mRNA | Kinases | Cancer therapies | Proteins | Signal transduction | Cell growth | Immunology | Epidermal growth factor | Enzymatic activity | Xenografts | Gallbladder | Food | Medical research | Pyruvate kinase | Non-small cell lung carcinoma | Tumor cell lines | Metabolism | Gene expression | Chemotherapy | Medical prognosis | Cell lines | Biomarkers | Hypoxia | Lactic acid | Viability | Cytoplasm | Tumors | Apoptosis
Journal Article
ILAR journal, ISSN 1084-2020, 04/2019
Institutional Animal Care and Use Committees (IACUCs) occasionally face regulatory requirements for which clear guidance may not be available. Either the...
Journal Article
Journal of translational medicine, ISSN 1479-5876, 12/2018, Volume 16, Issue 1, pp. 369 - 13
Previously, we have demonstrated that Interleukin 13 receptor alpha 2 (IL-13Rα2) is overexpressed in approximate 78% Glioblastoma multiforme (GBM) samples. We...
Transcription factors | IL-13Rα2 | IL-13 | AP-1 | Glioblastoma | Immunohistochemistry | Pediatrics | Biotechnology | Immunocytochemistry | Brain cancer | Gene regulation | Interleukin | Colorimetry | Statistical methods | Activation | Metastasis | Kinases | Ovarian cancer | Cell adhesion & migration | Proteins | Signal transduction | Receptors | Cell activation | Transcription activation | Immunotherapy | Glioma cells | Growth factors | c-Fos protein | Astrocytoma | Enzyme-linked immunosorbent assay | Statistical analysis | Cytokines | Activator protein 1 | c-Jun protein | Interleukin 13 | Tumor cell lines | Glioblastoma multiforme | Patients | Fra1 protein | Variance analysis | JunB protein | Signaling | Pancreatic cancer | Sampling methods | Transduction | Tumors
Transcription factors | IL-13Rα2 | IL-13 | AP-1 | Glioblastoma | Immunohistochemistry | Pediatrics | Biotechnology | Immunocytochemistry | Brain cancer | Gene regulation | Interleukin | Colorimetry | Statistical methods | Activation | Metastasis | Kinases | Ovarian cancer | Cell adhesion & migration | Proteins | Signal transduction | Receptors | Cell activation | Transcription activation | Immunotherapy | Glioma cells | Growth factors | c-Fos protein | Astrocytoma | Enzyme-linked immunosorbent assay | Statistical analysis | Cytokines | Activator protein 1 | c-Jun protein | Interleukin 13 | Tumor cell lines | Glioblastoma multiforme | Patients | Fra1 protein | Variance analysis | JunB protein | Signaling | Pancreatic cancer | Sampling methods | Transduction | Tumors
Journal Article
GUT, ISSN 0017-5749, 11/2014, Volume 63, Issue 11, pp. 1728 - 1728
Objective Previous studies have shown that ulcerative colitis (UC) is associated with the presence of lamina propria non-invariant (Type II) NKT cells...
INTERLEUKIN-13 | GASTROENTEROLOGY & HEPATOLOGY | RECEPTOR
INTERLEUKIN-13 | GASTROENTEROLOGY & HEPATOLOGY | RECEPTOR
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 08/2014, Volume 55, Issue 8, pp. 1323 - 1329
Interleukin-13 Pseudomonas exotoxin (IL-13PE), a targeted agent for interleukin-13 receptor α2 (IL-13Rα2)-expressing tumors, has been administered...
Brain tumor | IL-13PE | Radioiodination | Convection-enhanced delivery | Biodistribution | SPECT | Brain - diagnostic imaging | Humans | Tomography, Emission-Computed, Single-Photon | Tomography, X-Ray Computed | Pseudomonas | Receptors, Interleukin-13 - metabolism | Glioma - metabolism | Brain - metabolism | Tissue Distribution | Injections | Animals | Glioma - diagnostic imaging | Glioma - pathology | Immunotoxins - metabolism | Cell Line, Tumor | Isotope Labeling | Mice | Disease Models, Animal
Brain tumor | IL-13PE | Radioiodination | Convection-enhanced delivery | Biodistribution | SPECT | Brain - diagnostic imaging | Humans | Tomography, Emission-Computed, Single-Photon | Tomography, X-Ray Computed | Pseudomonas | Receptors, Interleukin-13 - metabolism | Glioma - metabolism | Brain - metabolism | Tissue Distribution | Injections | Animals | Glioma - diagnostic imaging | Glioma - pathology | Immunotoxins - metabolism | Cell Line, Tumor | Isotope Labeling | Mice | Disease Models, Animal
Journal Article