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1. Full Text Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial
by Panés, Julián, Prof and García-Olmo, Damián, MD and Van Assche, Gert, Prof and Colombel, Jean Frederic, Prof and Reinisch, Walter, Prof and Baumgart, Daniel C, Prof and Dignass, Axel, Prof and Nachury, Maria, MD and Ferrante, Marc, Prof and Kazemi-Shirazi, Lili, Prof and Grimaud, Jean C, Prof and de la Portilla, Fernando, Prof and Goldin, Eran, Prof and Richard, Marie Paule, MD and Leselbaum, Anne, MD and Danese, Silvio, Prof and ADMIRE CD Study Grp Collaborators and ADMIRE CD Study Group Collaborators
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10051, pp. 1281 - 1290
Summary Background Complex perianal fistulas in Crohn's disease are challenging to treat. Allogeneic, expanded, adipose-derived stem cells (Cx601) are a... 
Internal Medicine | 6-MERCAPTOPURINE | ANAL FISTULAS | MEDICINE, GENERAL & INTERNAL | THERAPY | ACTIVITY INDEX | METRONIDAZOLE | INFLIXIMAB | CIPROFLOXACIN | REMISSION | LONG | Double-Blind Method | Rectal Fistula - etiology | Europe | Humans | Middle Aged | Rectal Fistula - surgery | Male | Treatment Outcome | Combined Modality Therapy | Evidence-Based Medicine | Transplantation, Homologous | Crohn Disease - complications | Rectal Fistula - therapy | Rectal Fistula - pathology | Mesenchymal Stromal Cells | Adult | Female | Aged | Israel | Adipose Tissue | Mesenchymal Stem Cell Transplantation | Medical colleges | Hospitals | Gastrointestinal diseases | Stem cells | Clinical trials | Fistula | Health aspects | Spain | Tumor necrosis factor-TNF | Inflammation | Medical treatment | Crohns disease | Index Medicus | Abridged Index Medicus
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2. Full Text What is Disease Progression in Crohn’s Disease and how can it be Measured?
by Panés, Julián
Journal of Crohn's and Colitis, ISSN 1873-9946, 8/2015, Volume 9, Issue 8, pp. 599 - 600
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3. Full Text Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study
by Feagan, Brian G, Prof and Sandborn, William J, MD and D'Haens, Geert, Prof and Panés, Julián, Prof and Kaser, Arthur, Prof and Ferrante, Marc, Prof and Louis, Edouard, Prof and Franchimont, Denis, Prof and Dewit, Olivier, Prof and Seidler, Ursula, Prof and Kim, Kyung-Jo, Prof and Neurath, Markus F, Prof and Schreiber, Stefan, Prof and Scholl, Paul, MB BChir and Pamulapati, Chandrasena, PhD and Lalovic, Bojan, PhD and Visvanathan, Sudha, PhD and Padula, Steven J, MD and Herichova, Ivona, PhD and Soaita, Adina, PhD and Hall, David B, PhD and Böcher, Wulf O, Prof
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10080, pp. 1699 - 1709
Summary Background The interleukin-23 pathway is implicated genetically and biologically in the pathogenesis of Crohn's disease. We aimed to assess the... 
Internal Medicine | TRIAL | CELLS | MEDICINE, GENERAL & INTERNAL | ANTI-TNF | INFLAMMATORY-BOWEL-DISEASE | EFFICACY | ULCERATIVE-COLITIS | NECROSIS-FACTOR ANTAGONISTS | ANTITUMOR | MAINTENANCE THERAPY | FACTOR-ALPHA | Clinical trials | Monoclonal antibodies | Medicine, Experimental | Medical research | Interleukins | Intravenous administration | Pathogenesis | Mucosa | Interleukin | Interleukin 23 | Antagonists | Intravenous therapy | Randomization | Endoscopes | Motivation | Gastroenterology | Remission | Tumor necrosis factor-TNF | Colon | Safety | Active control | Chronic illnesses | Psoriasis | Cytokines | Ileitis | Nausea | Inflammation | Crohn's disease | Disease control | Patients | Ileum | Crohns disease | Inflammatory bowel disease | Interactive systems | Tumor necrosis factor | Ulcers | TNF inhibitors | Tumors | Index Medicus | Abridged Index Medicus
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4. Full Text Preface
by Panés, Julián
Digestive Diseases, ISSN 0257-2753, 09/2013, Volume 31, Issue 2, pp. 185 - 185
Preface
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5. Full Text Response to Gracie and Ford
by Marín-Jiménez, Ignacio and Panés, Julián
American Journal of Gastroenterology, ISSN 0002-9270, 06/2016, Volume 111, Issue 6, pp. 901 - 902
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6. Full Text Preface
by Panés, Julián
Digestive Diseases, ISSN 0257-2753, 09/2013, Volume 31, Issue 2, p. 185
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7. Full Text Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
by Anderson, Carl A and Boucher, Gabrielle and Lees, Charlie W and Franke, Ane and D'Amato, Mauro and Taylor, Kent D and Lee, James C and Goyette, Philippe and Imielinski, Marcin and Latiano, Anna and Lagacé, Caroline and Scott, Regan and Amininejad, Leila and Bumpstead, Suzannah and Baidoo, Leonard and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Colombel, Jean-Frédéric and Denson, Lee A and de Vos, Martine and Dubinsky, Marla and Edwards, Cathryn and Ellinghaus, David and Fehrmann, Rudolf S. N and Floyd, James A. B and Florin, Timothy and Franchimont, Denis and Franke, Lude and Georges, Michel and Glas, Jürgen and Glazer, Nicole L and Guthery, Stephen L and Haritunians, Talin and Hayward, Nicholas K and Hugot, Jean-Pierre and Jobin, Gilles and Laukens, Debby and Lawrance, Ian and Lémann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and McGovern, Dermot P and Milla, Monica and Montgomery, Grant W and Morley, Katherine I and Mowat, Craig and Ng, Aylwin and Newman, William and Ophoff, Roel A and Papi, Laura and Palmieri, Orazio and Peyrin-Biroulet, Laurent and Panés, Julián and Phillips, Anne and Prescott, Natalie J and Proctor, Deborah D and Roberts, Rebecca and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Schumm, Philip and Seibold, Frank and Sharma, Yashoda and Simms, Lisa A and Seielstad, Mark and Steinhart, A. Hillary and Targan, Stephan R and van den Berg, Leonard H and Vatn, Morten and Verspaget, Hein and Walters, Thomas and Wijmenga, Cisca and Wilson, David C and Westra, Harm-Jan and Xavier, Ramnik J and Zhao, Zhen Z and Ponsioen, Cyriel Y and Andersen, Vibeke and Torkvist, Leif and Gazouli, Maria and Anagnou, Nicholas P and Karlsen, Tom H and Kupcinskas, Limas and Sventoraityte, Jurgita and Mansfield, John C and Kugathasan, Subra and Silverberg, Mark S and Halfvarson, Jonas and Rotter, Jerome I and Mathew, Christopher G and Griffiths, Anne M and Gearry, Richard and Ahmad, Tariq and Brant, Steven R and Chamaillard, Mathias and ... and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 3, pp. 246 - 252
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six... 
COMMON VARIANTS | CELLS | INFLAMMATORY-BOWEL-DISEASE | PROTEIN | CROHNS-DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | GENE-EXPRESSION | ENRICHMENT | MULTIPLE | GENOME-WIDE ASSOCIATION | Crohn Disease - genetics | Risk | Genome-Wide Association Study | Humans | Colitis, Ulcerative - genetics | Genetic aspects | Disease susceptibility | Research | Risk factors | Ulcerative colitis | Meta-analysis | Studies | Inflammatory bowel disease | Celiac disease | Genetics | Genomics | Genes | Index Medicus | Medicine | Medicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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8. Full Text Preface
by Panés, Julián
Digestive Diseases, ISSN 0257-2753, 2013, Volume 31, Issue 2, pp. 185 - 185
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9. Full Text Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis
by Dotti, Isabella and Mora-Buch, Rut and Ferrer-Picón, Elena and Planell, Núria and Jung, Peter and Masamunt, M Carme and Leal, Raquel Franco and Martín de Carpi, Javier and Llach, Josep and Ordás, Ingrid and Batlle, Eduard and Panés, Julián and Salas, Azucena
Gut, ISSN 0017-5749, 12/2017, Volume 66, Issue 12, pp. 2069 - 2079
ObjectiveUC is a chronic inflammatory disease of the colonic mucosa. Growing evidence supports a role for epithelial cell defects in driving pathology.... 
HUMAN COLON | CLAUDIN-18 | ANNEXIN A10 | ADENOCARCINOMA | GROUP-II PHOSPHOLIPASE-A2 | GASTROINTESTINAL-TRACT | BARRIER | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | MUCUS | STAGE-II | Immunohistochemistry | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Tissue Array Analysis | Colitis, Ulcerative - metabolism | Humans | Middle Aged | Epithelial Cells - pathology | Male | Colitis, Ulcerative - pathology | Stem Cells - metabolism | Case-Control Studies | Biopsy | Stem Cells - pathology | Adult | Female | Real-Time Polymerase Chain Reaction | Intestinal Mucosa - pathology | RNA - metabolism | Care and treatment | Messenger RNA | Epithelial cells | Anti-infective agents | Dosage and administration | Research | Ulcerative colitis | Inflammatory bowel diseases | Aquaporin 8 | Mucosa | Colorectal cancer | Genomes | Small intestine | Inflammatory diseases | Organoids | Intestine | Colonoscopy | Rodents | DNA methylation | Endoscopy | Phenotypes | Aquaporins | Gene expression | Epithelium | Patients | Chloride channels (calcium-gated) | Crohns disease | Inflammatory bowel disease | Hospitals | Stem cells | Index Medicus | Abridged Index Medicus | GENE EXPRESSION | INTESTINAL EPITHELIUM | STEM CELLS | Inflammatory Bowel Disease | ULCERATIVE COLITIS | 1506
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10. Full Text IBD: Regulatory T cells for treatment of Crohn's disease
by Salas, Azucena and Panés, Julián
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 06/2015, Volume 12, Issue 6, pp. 315 - 316
The suppression of excessive immune responses by infusion of regulatory T cells would require a product of high purity, adequate ex vivo expansion and... 
Crohn Disease - therapy | Crohn Disease - immunology | Humans | T-Lymphocytes, Regulatory - immunology | Index Medicus
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11. Full Text Efficacy of tofacitinib treatment in ulcerative colitis
by Panés, Julián and Gisbert, Javier P
Gastroenterologia y Hepatologia, ISSN 0210-5705, 06/2019, Volume 42, Issue 6, pp. 403 - 412
Tofacitinib is an oral synthetic small-molecule inhibitor of Janus kinases, which are involved in the pathogenesis of various inflammatory diseases,... 
Efficacy | Janus kinases | Tofacitinib | Ulcerative colitis
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12. Full Text Eficacia de tofacitinib en el tratamiento de la colitis ulcerosa
by Panés, Julián and Gisbert, Javier P
Gastroenterología y Hepatología, ISSN 0210-5705, 2019, Volume 42, Issue 6, pp. 403 - 412
ResumenTofacitinib es una molécula pequeña sintética, de administración oral, que actúa inhibiendo a las cinasas Janus implicadas en la patogénesis de diversas... 
Gastroenterology and Hepatology | Tofacitinib | Cinasas Janus | Efficacy | Janus kinases | Colitis ulcerosa | Eficacia | Ulcerative colitis
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13. Full Text What is Disease Progression in Crohn's Disease and how can it be Measured?
by Panés, Julián and Panés, Julián
Journal of Crohn's & colitis, ISSN 1873-9946, 08/2015, Volume 9, Issue 8, pp. 599 - 600
MAINTENANCE | MULTIPLE-SCLEROSIS | ADALIMUMAB | MAGNETIC-RESONANCE | CHARM TRIAL | INDEX | GASTROENTEROLOGY & HEPATOLOGY | DAMAGE | SEVERITY | REMISSION | Severity of Illness Index | Adalimumab - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Crohn Disease - drug therapy | Humans | Female | Male | Infliximab - therapeutic use | Index Medicus
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14. Full Text Adalimumab in Ulcerative Colitis: Can Pharmacodynamics Be Improved Based on Pharmacokinetics?
by Louis, Edouard and Panés, Julián
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 1, pp. 176 - 178
Gastroenterology and Hepatology
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15. JAK Inhibition: The Most Promising Agents in the IBD Pipeline?
by Fernandez-Clotet, A and Castro-Poceiro, J and Panes, J
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2019, Volume 25, Issue 1, pp. 32 - 40
Under current therapeutic algorithms, half of the patients with moderate-severe ulcerative colitis or Crohn's disease fail in achieving a sustained remission.... 
RHEUMATOID-ARTHRITIS | new therapies | CROHNS-DISEASE | ULCERATIVE-COLITIS | Crohn's disease | FILGOTINIB GLPG0634 | MAINTENANCE THERAPY | Inflammatory bowel disease | SELECTIVE INHIBITOR | JANUS KINASE INHIBITOR | PHASE IIB | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | JAK inhibitors | small molecules | T-CELLS | Ulcerative colitis
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16. Full Text Reply
by Panés, Julián and López–Sanromán, Antonio
Gastroenterology, ISSN 0016-5085, 03/2014, Volume 146, Issue 3, pp. 869 - 870
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17. Full Text Reply
by Panés, Julián and López–Sanromán, Antonio
Gastroenterology, ISSN 0016-5085, 03/2014, Volume 146, Issue 3, pp. 869 - 870
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18. Full Text Reply
by Panés, Julián and López–Sanromán, Antonio
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 3, pp. 869 - 870
Gastroenterology and Hepatology
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19. Full Text Reply
by Panés, Julián and López-Sanromán, Antonio
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 3, pp. 869 - 870
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20. Full Text Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
by Franke, Ane and McGovern, Dermot P. B and Barrett, Jeffrey C and Wang, Kai and Radford-Smith, Graham L and Ahmad, Tariq and Lees, Charlie W and Balschun, Tobias and Lee, James and Roberts, Rebecca and Anderson, Carl A and Bis, Joshua C and Bumpstead, Suzanne and Ellinghaus, David and Festen, Eleonora M and Georges, Michel and Green, Todd and Haritunians, Talin and Jostins, Luke and Latiano, Anna and Mathew, Christopher G and Montgomery, Grant W and Prescott, Natalie J and Raychaudhuri, Soumya and Rotter, Jerome I and Schumm, Philip and Sharma, Yashoda and Simms, Lisa A and Taylor, Kent D and Whiteman, David and Wijmenga, Cisca and Baldassano, Robert N and Barclay, Murray and Bayless, Theodore M and Brand, Stephan and Büning, Carsten and Cohen, Albert and Colombel, Jean-Frederick and Cottone, Mario and Stronati, Laura and Denson, Ted and de Vos, Martine and D'Inca, Renata and Dubinsky, Marla and Edwards, Cathryn and Florin, Tim and Franchimont, Denis and Gearry, Richard and Glas, Jürgen and van Gossum, Ane and Guthery, Stephen L and Halfvarson, Jonas and Verspaget, Hein W and Hugot, Jean-Pierre and Karban, Amir and Laukens, Debby and Lawrance, Ian and Lemann, Marc and Levine, Arie and Libioulle, Cecile and Louis, Edouard and Mowat, Craig and Newman, William and Panés, Julián and Phillips, Anne and Proctor, Deborah D and Regueiro, Miguel and Russell, Richard and Rutgeerts, Paul and Sanderson, Jeremy and Sans, Miquel and Seibold, Frank and Steinhart, A. Hillary and Stokkers, Pieter C. F and Torkvist, Leif and Kullak-Ublick, Gerd and Wilson, David and Walters, Thomas and Targan, Stephan R and Brant, Steven R and Rioux, John D and D'Amato, Mauro and Weersma, Rinse K and Kugathasan, Subra and Griffiths, Anne M and Mansfield, John C and Vermeire, Severine and Duerr, Richard H and Silverberg, Mark S and Satsangi, Jack and Schreiber, Stefan and Cho, Judy H and Annese, Vito and Hakonarson, Hakon and Daly, Mark J and Parkes, Miles and Hälsoakademin and Örebro universitet
Nature genetics, ISSN 1061-4036, 2010, Volume 42, Issue 12, pp. 1118 - 1125
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls... 
COMMON VARIANTS | ACTIVATION | INFLAMMATORY-BOWEL-DISEASE | PROTEIN | NEDD4 FAMILY | GENE | GENETICS & HEREDITY | SEQUENCE VARIANTS | RECEPTOR | IDENTIFICATION | ASSOCIATION | Genetic Variation | Crohn Disease - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Humans | Computational Biology | Genetic Loci - genetics | Crohn Disease - etiology | Genome, Human - genetics | Genetic Linkage | Care and treatment | Methyltransferases | Physiological aspects | Disease susceptibility | Genetic aspects | Crohn's disease | Research | Risk factors | Inflammatory bowel disease | Genetics | Genomics | Meta-analysis | Index Medicus | Medicine | Medicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
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