X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (403) 403
Patent (48) 48
Magazine Article (22) 22
Publication (12) 12
Dissertation (6) 6
Book / eBook (3) 3
Book Chapter (3) 3
Conference Proceeding (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (63) 63
index medicus (55) 55
apoptosis (44) 44
animals (42) 42
oncology (41) 41
cancer (34) 34
mice (34) 34
apoptosis - drug effects (30) 30
cell line, tumor (29) 29
male (27) 27
antineoplastic agents - pharmacology (25) 25
cell proliferation - drug effects (23) 23
leukemia (23) 23
mutation (20) 20
mice, nude (19) 19
female (17) 17
kinases (17) 17
phosphorylation (17) 17
proteins (17) 17
xenograft model antitumor assays (17) 17
human necessities (16) 16
research (16) 16
tyrosine kinase inhibitor (16) 16
chronic myeloid-leukemia (15) 15
in-vitro (15) 15
mice, inbred balb c (14) 14
physics (14) 14
beta-catenin (12) 12
imatinib mesylate (12) 12
signal transduction - drug effects (12) 12
tyrosine (12) 12
cell biology (11) 11
chronic myelogenous leukemia (11) 11
drug synergism (11) 11
health aspects (11) 11
imatinib (11) 11
metastasis (11) 11
activation (10) 10
biochemistry & molecular biology (10) 10
cell proliferation (10) 10
cell survival - drug effects (10) 10
genetic aspects (10) 10
neoplastic stem cells - drug effects (10) 10
tumors (10) 10
adult (9) 9
analysis (9) 9
bcr-abl (9) 9
chronic myeloid leukemia (9) 9
inhibition (9) 9
leukemia, myelogenous, chronic, bcr-abl positive - drug therapy (9) 9
protein kinase inhibitors - pharmacology (9) 9
学生 (9) 9
课堂教学 (9) 9
cancer-cells (8) 8
care and treatment (8) 8
cell cycle - drug effects (8) 8
chemotherapy (8) 8
diagnosis (8) 8
electricity (8) 8
gene expression (8) 8
hemic and lymphatic diseases (8) 8
invasion (8) 8
leukemia, myelogenous, chronic, bcr-abl positive - genetics (8) 8
melanoma (8) 8
middle aged (8) 8
pyrimidines - pharmacology (8) 8
signal transduction (8) 8
β-catenin (8) 8
bone marrow (7) 7
cell cycle (7) 7
cell movement - drug effects (7) 7
chemistry (7) 7
down-regulation (7) 7
drug resistance (7) 7
expression (7) 7
flow cytometry (7) 7
growth (7) 7
hygiene (7) 7
leukemia, myelogenous, chronic, bcr-abl positive - pathology (7) 7
mechanisms (7) 7
medical or veterinary science (7) 7
myeloid leukemia (7) 7
niclosamide (7) 7
optics (7) 7
philadelphia-chromosome (7) 7
resistance (7) 7
science (7) 7
stem cells (7) 7
stem-cells (7) 7
survival (7) 7
therapy (7) 7
triptolide (7) 7
精选 (7) 7
语文教学 (7) 7
article (6) 6
biology (6) 6
cancer stem-cells (6) 6
cancer stem-like cells (6) 6
cell migration (6) 6
cell survival (6) 6
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


British Journal of Pharmacology, ISSN 0007-1188, 08/2017, Volume 174, Issue 15, pp. 2427 - 2443
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2017, Volume 174, Issue 15, pp. 2427 - 2443
Background and Purpose Aberrant activation of the cyclin D1‐cyclin‐dependent kinase 4/6 (CDK4/6)‐Rb signalling pathway is common in oesophageal squamous cell... 
EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | 1ST-LINE TREATMENT | STEM-CELLS | CONCISE GUIDE | SIGNALING PATHWAY | CDK4/6 INHIBITION | PHARMACOLOGY & PHARMACY | COMBINATION | PD 0332991 | PANCREATIC-CANCER CELLS | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Apoptosis - drug effects | Carcinoma, Squamous Cell - pathology | Humans | Male | Structure-Activity Relationship | Esophageal Neoplasms - pathology | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Tumor Cells, Cultured | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Esophageal Squamous Cell Carcinoma | Cell Survival - drug effects | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Piperazines - pharmacology | Cell Movement - drug effects | Animals | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Esophageal Neoplasms - drug therapy | Neoplasms, Experimental - drug therapy | Squamous cell carcinoma | Metastasis | Analysis | Esophageal cancer | Fluorouracil | Apoptosis | Flow cytometry | Animal models | Senescence | Wound healing | Leukocyte migration | 5-Fluorouracil | Cyclin-dependent kinases | Cyclin D1 | Cisplatin | Cyclin-dependent kinase 4 | Metastases | Esophagus | Cell adhesion & migration | Gelatinase A | Cyclin-dependent kinase | Signal transduction | Mitochondria | Xenografts | Annexin V | Cell migration | Tumors | Research Papers | Research Paper
Journal Article
Journal of Hematology & Oncology, ISSN 1756-8722, 12/2012, Volume 5, Issue S1, pp. A6 - A6
  Doc number: A6 
Proteins | Kinases | Addictions | Leukemia | Cancer
Journal Article
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 2018, Volume 18, Issue 10, pp. 988 - 998
Background: Uveal melanoma is the most common primary intraocular malignancy in adults. So far, there have been no effective targeted therapeutic agents in... 
Uveal melanoma | Cancer stem-like cells | Artesunate | Migration | Wnt/β-catenin | Invasion | APOPTOSIS | uveal melanoma | SURVIVIN | BETA-CATENIN | CANCER | cancer stem-like cells | STEM-LIKE CELLS | invasion | GENE | ONCOLOGY | Wnt/beta-catenin | migration | ABSENCE | MUTATIONS | ARTEMISININ
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2016, Volume 126, Issue 10, pp. 3961 - 3980
lmatinib-insensitive leukemia stem cells (LSCs) are believed to be responsible for resistance to BCR-ABL tyrosine kinase inhibitors and relapse of chronic... 
PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | TYROSINE KINASE | SYMMETRIC DIMETHYLATION | PHILADELPHIA-CHROMOSOME | ARGININE METHYLTRANSFERASE | BONE-MARROW | BETA-CATENIN | IMATINIB MESYLATE | CHRONIC MYELOID-LEUKEMIA | ONCOGENE ADDICTION | RNA, Small Interfering - genetics | Cell Proliferation | Neoplastic Stem Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | Molecular Targeted Therapy | Gene Knockdown Techniques | STAT5 Transcription Factor - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | 1-Naphthylamine - pharmacology | HEK293 Cells | Female | Antineoplastic Agents - pharmacology | Protein-Arginine N-Methyltransferases - genetics | Aminoquinolines - pharmacology | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Gene Expression | Cell Survival | Imatinib Mesylate - pharmacology | Mice, Inbred C57BL | Enzyme Induction | Pyrimidines - pharmacology | Mice, SCID | Protein-Arginine N-Methyltransferases - metabolism | 1-Naphthylamine - analogs & derivatives | Xenograft Model Antitumor Assays | Animals | Cell Line, Tumor | Mice, Inbred NOD | Carbazoles - pharmacology | Neoplastic Stem Cells - enzymology | Fusion Proteins, bcr-abl - metabolism | Care and treatment | Methyltransferases | Development and progression | Genetic aspects | Chronic myeloid leukemia | Properties | Gene expression | Health aspects | Cloning | Leukemia | Mortality | Science | Grants | Kinases | Experiments | Proteins | Stem cells | DNA methylation | Epigenetics | Mutation | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 3, pp. 789 - 803
Purpose: Leukemia stem cells (LSC), which are insensitive to tyrosine kinase inhibitors (TKI), are an important source of TKI resistance and disease relapse in... 
CANCER-CELLS | ACTIVATION | ONCOLOGY | PHILADELPHIA-CHROMOSOME | IN-VIVO | IMATINIB | TRANSCRIPTION | BETA-CATENIN | NF-KAPPA-B | CHRONIC MYELOID-LEUKEMIA | CML STEM | RNA, Small Interfering - genetics | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Drug Resistance, Neoplasm | Neoplasm Proteins - metabolism | Cell Self Renewal - drug effects | Heterografts | Chromatin Immunoprecipitation | RNA Interference | Niclosamide - pharmacology | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Antineoplastic Agents - pharmacology | Promoter Regions, Genetic | Graft Survival | Gene Expression Regulation, Leukemic | Mice, SCID | beta Catenin - metabolism | Mice, Knockout | Protein Interaction Mapping | Interleukin Receptor Common gamma Subunit - deficiency | Fusion Proteins, bcr-abl - genetics | Animals | Transcription Factor RelA - metabolism | Anthelmintics - pharmacology | Fusion Proteins, bcr-abl - antagonists & inhibitors | K562 Cells | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Feedback, Physiological - drug effects | Mice, Inbred NOD | Protein Kinase Inhibitors - pharmacology | Forkhead Box Protein M1 - metabolism | Chromatin | Immunoprecipitation | Severe combined immunodeficiency | Transcription | Leukemia | Niclosamide | Stem cell transplantation | Feedback loops | Kinases | Positive feedback | Recruitment | Disease resistance | β-catenin | Allografts | Protein-tyrosine kinase | Tyrosine | CD34 antigen | Translocation | NF-κB protein | Myeloid leukemia | Chronic myeloid leukemia | Survival | Nuclear transport | Experimental design | Stem cells | Regulatory mechanisms (biology) | Mice | Cancer
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 06/2018, Volume 36, Issue 4, pp. 228 - 240
Journal Article
Current cancer drug targets, 2018, Volume 18, Issue 10, p. 988
Uveal melanoma is the most common primary intraocular malignancy in adults. So far, there have been no effective targeted therapeutic agents in patients with... 
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 400, pp. 47 - 60
Abstract Uveal melanoma (UM) is the most common intraocular malignant neoplasm in adults. Despite the availability of enucleation, radiation and chemotherapy,... 
Hematology, Oncology and Palliative Medicine | Uveal melanoma | Epigenetics | HDAC inhibitor | β-catenin | Migration and invasion | Cancer stem-like cells | beta-catenin | APOPTOSIS | METASTASIS | CATENIN | OVARIAN-CANCER | CANCER STEM-CELLS | INVASION | ONCOLOGY | PATHWAY | LEUKEMIA | HISTONE DEACETYLASE INHIBITORS | HUMAN MAST-CELLS | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Melanoma - enzymology | Male | Depsipeptides - pharmacology | Uveal Neoplasms - enzymology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cell Self Renewal - drug effects | Dose-Response Relationship, Drug | Transfection | RNA Interference | Time Factors | Melanoma - genetics | Neoplastic Stem Cells - pathology | Histone Deacetylase 1 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Aldehyde Dehydrogenase - metabolism | Histone Deacetylase 1 - genetics | Uveal Neoplasms - genetics | Uveal Neoplasms - pathology | Matrix Metalloproteinase 2 - metabolism | Neoplasm Invasiveness | Bcl-2-Like Protein 11 - genetics | Mitochondria - metabolism | Melanoma - pathology | Mitochondria - drug effects | Mitochondria - pathology | Mice, SCID | Uveal Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Bcl-2-Like Protein 11 - metabolism | Wnt Signaling Pathway - drug effects | Tumor Burden - drug effects | Melanoma - drug therapy | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Mice, Inbred NOD | Cell Proliferation - drug effects | Vinblastine - pharmacology | Neoplastic Stem Cells - enzymology | Histone Deacetylase 1 - metabolism | Epigenetic inheritance | Chemotherapy | Melanoma | Histones | Ophthalmology | Metastasis | Mitogens | Protein kinases | Cancer | Histone deacetylase | Seeds | Wnt protein | Leukocyte migration | Radiation | Kinases | Metastases | Ovarian cancer | Cell growth | Xenografts | Inhibition | Immunoglobulins | Pharmacology | Chemical compounds | Patients | Gelatinase A | Enucleation | Inhibitors | Adults | In vitro methods and tests | Cell migration | BIM protein | Apoptosis
Journal Article
Journal Article