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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2015, Volume 112, Issue 6, pp. 1779 - 1784
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2015, Volume 14, Issue 7 Supplement, pp. IA15 - IA15
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 11/2014, Volume 12, Issue 11 Supplement, pp. IA3 - IA3
Journal Article
Cancer Research, ISSN 0008-5472, 10/2013, Volume 73, Issue 19 Supplement, pp. IA12 - IA12
Journal Article
Cell, ISSN 0092-8674, 4/2018, Volume 173, Issue 3, pp. 649 - 664.e20
Resistance to chemotherapy plays a significant role in cancer mortality. To identify genetic units affecting sensitivity to cytarabine, the mainstay of... 
Journal Article
Cell, ISSN 0092-8674, 2011, Volume 146, Issue 3, pp. 353 - 358
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 08/2018, Volume 8, pp. 340 - 340
Precision medicine holds real promise for the treatment of cancer. Adapting therapeutic strategies so patients receive individualized treatment protocols, will... 
Co-Clinical Trial | Precision medicine | Mouse models | PDX | Mouse Hospital | Cancer | mouse models | STEM-CELLS | CLINICAL TRIAL PROJECT | TUMOR ORGANOIDS | ORGANOID TRANSPLANTATION | DRUG-RESISTANCE | HETEROGENEITY | MODELS | ONCOLOGY | PROSTATE-CANCER | precision medicine | cancer | MICE | PATIENT-DERIVED XENOGRAFTS | Care and treatment | Research | Patient outcomes | Oncology, Experimental | Methods
Journal Article
Cancer discovery, ISSN 2159-8274, 06/2019, Volume 9, Issue 9, pp. CD-18-0083 - 1323
The function of PTEN in the cytoplasm largely depends on its lipid-phosphatase activity, though which it antagonizes the PI3K-AKT oncogenic pathway. However,... 
Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 601 - 601
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2012, Volume 122, Issue 8, pp. 2765 - 2768
Small nucleolar RNAs (snoRNAs) are emerging as an important new class of genes deregulated in cancer. Orphans snoRNAs are encoded outside of ribosomal protein... 
NONCODING RNA | MULTIPLE-MYELOMA | MEDICINE, RESEARCH & EXPERIMENTAL | MMSET | SMALL NUCLEOLAR RNAS | GROWTH | PTEN | SNORNA HOST GENES | GAS5 | MICRORNA | Genetic aspects | Genetic engineering | MicroRNA | Genes | Multiple myeloma | Cancer
Journal Article
Oncogene, ISSN 0950-9232, 09/2008, Volume 27, Issue 41, pp. 5385 - 5385
Journal Article
Cell, ISSN 0092-8674, 2000, Volume 100, Issue 4, pp. 387 - 390
In his celebrated monolog, the Shakespearean hero Hamlet clearly identified two extreme remedies: “To die: to sleep; no more” against “the heartache and the... 
Phosphatases | Tumors
Journal Article
Cancer discovery, ISSN 2159-8274, 4/2017, Volume 7, Issue 4, pp. 359 - 368
The activity of RNA is controlled by different types of post-transcriptional modifications, such as the addition of methyl groups and other chemical and... 
Journal Article
Oncogene, ISSN 0950-9232, 04/2004, Volume 23, Issue 18, pp. 3134 - 3137
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1388, pp. 139 - 154
PTEN expression can be dysregulated in cancers via multiple mechanisms including genomic loss, epigenetic silencing, transcriptional repression, and... 
PTEN | ceRNA | miRNA | MicroRNA | Competing endogenous RNA | PTEN Phosphohydrolase - genetics | Computational Biology - methods | Animals | HCT116 Cells | Humans | Gene Expression Regulation | Mice | MicroRNAs - genetics | RNA - genetics | Index Medicus
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1388, pp. 289 - 306
Manipulation of mammalian genome and generation of genetically engineered mouse models (GEMMs) has revolutionized the scientific approach to address biological... 
Knock-in mice | PTEN | Southern blot analysis | Embryonic stem cells | Point mutations | DNA sequencing | PTEN Phosphohydrolase - genetics | Animals | Neoplasms - genetics | Mice | Mutation | Gene Knock-In Techniques - methods | Disease Models, Animal | Index Medicus
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 11/2002, Volume 22, Issue 22, pp. 7831 - 7841
Journal Article
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