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science & technology (274) 274
life sciences & biomedicine (271) 271
gastroenterology & hepatology (200) 200
humans (195) 195
male (142) 142
gastroenterology and hepatology (113) 113
female (105) 105
adult (93) 93
ulcerative colitis (88) 88
middle aged (80) 80
abridged index medicus (72) 72
crohn's disease (71) 71
inflammatory bowel disease (71) 71
animals (65) 65
biological and medical sciences (65) 65
medical sciences (61) 61
treatment outcome (50) 50
severity of illness index (43) 43
gastroenterology. liver. pancreas. abdomen (39) 39
other diseases. semiology (38) 38
aged (35) 35
care and treatment (35) 35
inflammation (34) 34
stomach. duodenum. small intestine. colon. rectum. anus (34) 34
inflammatory bowel diseases (33) 33
rats (33) 33
crohn disease - drug therapy (32) 32
colitis, ulcerative - drug therapy (31) 31
rats, sprague-dawley (28) 28
endoscopy (26) 26
prospective studies (26) 26
adolescent (25) 25
gastroenterology (25) 25
pharmacology & pharmacy (25) 25
young adult (25) 25
crohn disease - diagnosis (24) 24
double-blind method (24) 24
magnetic resonance imaging (24) 24
medical research (24) 24
remission induction (24) 24
research (23) 23
clinical trials (22) 22
crohn disease - therapy (22) 22
patients (22) 22
quality of life (22) 22
mice (21) 21
crohns disease (20) 20
immunology (20) 20
medicine, experimental (20) 20
time factors (20) 20
anti-inflammatory agents - therapeutic use (19) 19
antibodies, monoclonal - therapeutic use (19) 19
colon - pathology (19) 19
colonoscopy (19) 19
crohn disease - pathology (19) 19
crohn’s disease (19) 19
endothelium (19) 19
gastrointestinal agents - therapeutic use (18) 18
intestinal mucosa - pathology (18) 18
risk factors (18) 18
intestine (17) 17
analysis (16) 16
case-control studies (16) 16
colitis, ulcerative - diagnosis (16) 16
diagnosis (16) 16
immunosuppressive agents - therapeutic use (16) 16
infliximab (16) 16
stem cells (16) 16
crohn disease - complications (15) 15
crohn disease - immunology (15) 15
leukocytes - physiology (15) 15
pharmacology. drug treatments (15) 15
colitis, ulcerative - pathology (14) 14
crohn disease - diagnostic imaging (14) 14
gastric mucosa - blood supply (14) 14
antibodies, monoclonal, humanized - therapeutic use (13) 13
dose-response relationship, drug (13) 13
health aspects (13) 13
inflammatory bowel diseases - pathology (13) 13
tofacitinib (13) 13
tumor necrosis factor-tnf (13) 13
adhesion molecules (12) 12
biomarkers (12) 12
colon (12) 12
cytokines (12) 12
disease models, animal (12) 12
follow-up studies (12) 12
gastrointestinal diseases (12) 12
hematology (12) 12
inflammatory bowel diseases - therapy (12) 12
intercellular adhesion molecule-1 - metabolism (12) 12
leukocytes (12) 12
medicine (12) 12
studies (12) 12
surgery (12) 12
surveys and questionnaires (12) 12
tumor necrosis factor (12) 12
tumor necrosis factor-alpha - antagonists & inhibitors (12) 12
usage (12) 12
hepatology (11) 11
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1. Full Text Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials
by Panés, Julian and Sandborn, William J and Schreiber, Stefan and Sands, Bruce E and Vermeire, Séverine and D'Haens, Geert and Panaccione, Remo and Higgins, Peter D R and Colombel, Jean-Frederic and Feagan, Brian G and Chan, Gary and Moscariello, Michele and Wang, Wenjin and Niezychowski, Wojciech and Marren, Amy and Healey, Paul and Maller, Eric
Gut, ISSN 0017-5749, 06/2017, Volume 66, Issue 6, pp. 1049 - 1059
CLINICAL TRIALS | IMMUNOLOGY | Crohn'S DISEASE | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Severity of Illness Index | Piperidines - administration & dosage | Double-Blind Method | Pyrimidines - administration & dosage | Humans | Middle Aged | Male | Protein Kinase Inhibitors - adverse effects | Remission Induction | Protein Kinase Inhibitors - administration & dosage | C-Reactive Protein - metabolism | Pyrroles - administration & dosage | Crohn Disease - blood | Crohn Disease - drug therapy | Piperidines - adverse effects | Pyrimidines - adverse effects | Pyrroles - adverse effects | Adult | Female | Maintenance Chemotherapy | Treatment outcome | Care and treatment | Tofacitinib | Patient outcomes | Crohn's disease | Dosage and administration | Drug therapy | Comparative analysis | Statistical analysis | C-reactive protein | Cytokines | Clinical trials | Patients | Crohns disease | Inflammatory bowel disease | Studies | Signal transduction | Gastroenterology | TNF inhibitors | Janus kinase | Remission | Index Medicus | Abridged Index Medicus | CROHN'S DISEASE | Inflammatory Bowel Disease | 1506
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2. Full Text Letter: accuracy of magnetic resonance index of activity score to predict response to biologics in Crohn's disease—authors' reply
by Rimola, Jordi and Panés, Julian and Ordás, Ingrid
Alimentary pharmacology & therapeutics, ISSN 0269-2813, 01/2021, Volume 53, Issue 1, pp. 207 - 208
Crohn Disease - diagnostic imaging | Magnetic Resonance Spectroscopy | Crohn Disease - drug therapy | Humans | Tumor Necrosis Factor Inhibitors | Tumor Necrosis Factor-alpha | Biological Products - therapeutic use | Crohn's disease | Index Medicus
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3. Full Text Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis
by Sandborn, William J and Su, Chinyu and Sands, Bruce E and D’Haens, Geert R and Vermeire, Séverine and Schreiber, Stefan and Danese, Silvio and Feagan, Brian G and Reinisch, Walter and Niezychowski, Wojciech and Friedman, Gary and Lawendy, Nervin and Yu, Dahong and Woodworth, Deborah and Mukherjee, Arnab and Zhang, Haiying and Healey, Paul and Panés, Julian and OCTAVE Induction 1 OCTAVE Inductio and OCTAVE Induction 1, OCTAVE Induction 2, and OCTAVE Sustain Investigators
The New England journal of medicine, ISSN 0028-4793, 05/2017, Volume 376, Issue 18, pp. 1723 - 1736
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Protein Kinase Inhibitors - pharmacokinetics | Pyrroles - pharmacokinetics | Double-Blind Method | Humans | Middle Aged | Induction Chemotherapy | Male | Protein Kinase Inhibitors - adverse effects | Chi-Square Distribution | Remission Induction | Janus Kinases - antagonists & inhibitors | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Piperidines - adverse effects | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Pyrroles - adverse effects | Adult | Female | Piperidines - pharmacokinetics | Maintenance Chemotherapy | Colitis, Ulcerative - drug therapy | Pyrroles - therapeutic use | Treatment outcome | Tofacitinib | Patient outcomes | Analysis | Dosage and administration | Drug therapy | Ulcerative colitis | Inflammatory bowel disease | Studies | Colon | Gastroenterology | Pharmaceuticals | Index Medicus | Abridged Index Medicus
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4. Full Text Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme
by Sandborn, William J and Panés, Julian and Sands, Bruce E and Reinisch, Walter and Su, Chinyu and Lawendy, Nervin and Koram, Nana and Fan, Haiyun and Jones, Thomas V and Modesto, Irene and Quirk, Daniel and Danese, Silvio
Alimentary pharmacology & therapeutics, ISSN 0269-2813, 11/2019, Volume 50, Issue 10, pp. 1068 - 1076
Gastroenterology & Hepatology | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Venous Thrombosis - chemically induced | Humans | Middle Aged | Male | Pulmonary Embolism - epidemiology | Colitis, Ulcerative - epidemiology | Incidence | Young Adult | Pyrroles - adverse effects | Adult | Female | Retrospective Studies | Colitis, Ulcerative - drug therapy | Pyrroles - therapeutic use | Venous Thromboembolism - epidemiology | Risk Factors | Piperidines - therapeutic use | Pyrimidines - therapeutic use | Piperidines - adverse effects | Venous Thrombosis - epidemiology | Pyrimidines - adverse effects | Venous Thromboembolism - chemically induced | Aged | Pulmonary Embolism - chemically induced | Cohort Studies | Exposure | Maintenance | Risk analysis | Patients | Thrombosis | Two phase | Embolism | Risk factors | Inflammatory bowel disease | Thromboembolism | Health risk assessment | Ulcerative colitis | Index Medicus | Tofacitinib and Venous Thromboembolism in Uc | Original
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5. Increased response and remission rates in short-duration crohn's disease with subcutaneous certolizumab pegol: An analysis of PRECiSE 2 randomized maintenance trial data
by Schreiber, Stefan and Colombel, Jean-Frédéric and Bloomfield, Ralph and Nikolaus, Susanna and Schölmerich, Jürgen and Panés, Julian and Sandborn, William J and PRECISE 2 Study Investigators and PRECiSE 2 Study Investigators
The American journal of gastroenterology, ISSN 0002-9270, 07/2010, Volume 105, Issue 7, pp. 1574 - 1582
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Certolizumab Pegol | Prognosis | Double-Blind Method | Humans | Middle Aged | Immunologic Factors - administration & dosage | Logistic Models | Male | Treatment Outcome | Immunoglobulin Fab Fragments - therapeutic use | Polyethylene Glycols - therapeutic use | Remission Induction | Polyethylene Glycols - administration & dosage | Antibodies, Monoclonal, Humanized | Immunoglobulin Fab Fragments - administration & dosage | Crohn Disease - pathology | Crohn Disease - drug therapy | Injections, Subcutaneous | Placebos | Adult | Female | Aged | Drug Therapy, Combination | Immunologic Factors - therapeutic use
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6. Full Text Drug development in IBD: from novel target identification to early clinical trials
by Danese, Silvio and Fiocchi, Claudio and Panés, Julián
Gut, ISSN 0017-5749, 08/2016, Volume 65, Issue 8, pp. 1233 - 1239
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Index Medicus | Abridged Index Medicus
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7. Full Text Stem cell therapy for perianal fistulas in Crohn's disease
by Panes, Julian
Gastroenterology & hepatology, ISSN 1554-7914, 10/2016, Volume 12, Issue 10, pp. 637 - 640
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8. Full Text JAK Inhibitors: Back to Small Molecules for the Treatment of IBD
by Panes, Julian and Vermeire, Severine
Journal of Crohn's and colitis, ISSN 1873-9946, 07/2020, Volume 14, Issue Supplement_2, pp. S711 - S712
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Index Medicus | ulcerative colitis | AcademicSubjects | MED00260 | JAK inhibitors | Crohn’s disease
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9. Full Text Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
by Vermeire, Séverine, Dr and O'Byrne, Sharon, MD and Keir, Mary, PhD and Williams, Marna, PhD and Lu, Timothy T, MD and Mansfield, John C, MD and Lamb, Christopher A, MD and Feagan, Brian G, MD and Panes, Julian, MD and Salas, Azucena, PhD and Baumgart, Daniel C, MD and Schreiber, Stefan, MD and Dotan, Iris, MD and Sandborn, William J, MD and Tew, Gaik W, MSc and Luca, Diana, PhD and Tang, Meina T, PhD and Diehl, Lauri, DVM and Eastham-Anderson, Jeffrey, MS and De Hertogh, Gert, MD and Perrier, Clementine, PhD and Egen, Jackson G, PhD and Kirby, John A, PhD and van Assche, Gert, MD and Rutgeerts, Paul, MD
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 384, Issue 9940, pp. 309 - 318
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | General aspects | Medical sciences | Other diseases. Semiology | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Humans | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Antibodies, Monoclonal, Humanized - administration & dosage | Time Factors | Antibodies, Monoclonal - administration & dosage | Adult | Female | Remission Induction - methods | Colitis, Ulcerative - drug therapy | Monoclonal antibodies | Drug therapy | Health aspects | Analysis | Ulcerative colitis | Integrins | Inflammatory bowel disease | Flow cytometry | Ostomy | Biopsy | Gene expression | Drug dosages | Patients | Immune system | Index Medicus | Abridged Index Medicus
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10. Full Text Tofacitinib, an Oral Janus Kinase Inhibitor, in Active Ulcerative Colitis
by Sandborn, William J and Ghosh, Subrata and Panes, Julian and Vranic, Ivana and Su, Chinyu and Rousell, Samantha and Niezychowski, Wojciech and Study A3921063 Investigators
The New England journal of medicine, ISSN 0028-4793, 08/2012, Volume 367, Issue 7, pp. 616 - 624
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | General aspects | Medical sciences | Other diseases. Semiology | Double-Blind Method | Administration, Oral | Lipoproteins, HDL - blood | Pyrimidines - administration & dosage | Humans | Middle Aged | Male | Protein Kinase Inhibitors - adverse effects | Remission Induction | Dose-Response Relationship, Drug | Janus Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Pyrroles - administration & dosage | Piperidines | Pyrimidines - adverse effects | Pyrroles - adverse effects | Adult | Female | Colitis, Ulcerative - drug therapy | Pyrroles - therapeutic use | Lipoproteins, LDL - blood | Treatment outcome | Dosage and administration | Diagnosis | Tofacitinib | Drug therapy | Ulcerative colitis | Inflammatory bowel diseases | Cytokines | Clinical trials | Patients | Bleeding | Cholesterol | Inflammatory bowel disease | Cell activation | Interleukins | Rectum | Janus kinase | Remission | Colon | Immune system | Index Medicus | Abridged Index Medicus
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11. Full Text Development of the Lémann Index to Assess Digestive Tract Damage in Patients With Crohn's Disease
by Pariente, Benjamin and Mary, Jean-Yves and Danese, Silvio and Chowers, Yehuda and De Cruz, Peter and D’Haens, Geert and Loftus, Edward V and Louis, Edouard and Panés, Julian and Schölmerich, Jürgen and Schreiber, Stefan and Vecchi, Maurizio and Branche, Julien and Bruining, David and Fiorino, Gionata and Herzog, Matthias and Kamm, Michael A and Klein, Amir and Lewin, Maïté and Meunier, Paul and Ordas, Ingrid and Strauch, Ulrike and Tontini, Gian-Eugenio and Zagdanski, Anne-Marie and Bonifacio, Cristiana and Rimola, Jordi and Nachury, Maria and Leroy, Christophe and Sandborn, William and Colombel, Jean-Frédéric and Cosnes, Jacques
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2015, Volume 148, Issue 1, pp. 52 - 63.e3
Gastroenterology and Hepatology | Illness Index Severity | Response to Therapy | Prognosis | MRI | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Predictive Value of Tests | Prospective Studies | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Gastrointestinal Tract - pathology | Diagnostic Imaging - methods | Multimodal Imaging | Colonoscopy | Crohn Disease - diagnosis | Adult | Female | Severity of Illness Index | Crohn Disease - diagnostic imaging | Reproducibility of Results | Cross-Sectional Studies | Europe | Linear Models | Magnetic Resonance Imaging | Crohn Disease - pathology | Gastrointestinal Tract - diagnostic imaging | Israel | Australia | Observer Variation | Medicine, Experimental | Medical colleges | Medical research | Index Medicus | Abridged Index Medicus | Organic chemistry | Chemical Sciences
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