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Trends in Biochemical Sciences, ISSN 0968-0004, 04/2016, Volume 41, Issue 4, p. 386
Due to a production error, a low-resolution version of Figure 5 was inadvertently published in the version of the above Review article by Papasaikas and... 
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 01/2016, Volume 41, Issue 1, p. 33
  The spliceosome, one of the most complex machineries of eukaryotic cells, removes intronic sequences from primary transcripts to generate functional... 
Enzymes | Eukaryotes | Biochemistry | Ribonucleic acid--RNA
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 01/2016, Volume 41, Issue 1, pp. 33 - 45
The spliceosome, one of the most complex machineries of eukaryotic cells, removes intronic sequences from primary transcripts to generate functional messenger... 
Spliceosomes - chemistry | Spliceosomes - metabolism | Spliceosomes - genetics | Humans | RNA - chemistry | RNA - genetics | RNA - metabolism | Enzymes | Catalytic RNA
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2012, Volume 44, Issue 11, pp. 1236 - 1242
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 04/2016, Volume 41, Issue 4, pp. 386 - 386
RNA
Journal Article
Science, ISSN 0036-8075, 12/2012, Volume 338, Issue 6114, pp. 1547 - 1548
  In the chapter of The Origin of Species entitled "Difficulties on Theory," Charles Darwin found it "most difficult to conjecture by what transitions an organ... 
Alternative splicing | Vertebrates | Messenger RNA | Splicing | rev genes | Exons | Introns | Divergent evolution | Genes | PERSPECTIVES | Evolution | PROTEIN-INTERACTION NETWORKS | MULTIDISCIPLINARY SCIENCES | Evolutionary biology | Molecular biology | Gene expression | Genomics | Origins | Messages | Organs | Genomes | Syntax
Journal Article
Nature communications, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3639 - 15
Human pre-catalytic spliceosomes contain several proteins that associate transiently just prior to spliceosome activation and are absent in yeast, suggesting... 
SITE | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | MUTATION | U4/U6-CENTER-DOT-U5 TRI-SNRNP | HOMOLOGS | GENOME | PROGRESSION | PRE-MESSENGER-RNA | Yeasts | Alternative splicing | Regulators | Yeast | Splicing | Introns | RNA-mediated interference | Activation | mRNA | Gene expression | Proteins | Eukaryotes | Catalysis | Spliceosomes | Splicing factors
Journal Article
by Barbeira, Alvaro N and Dickinson, Scott P and Bonazzola, Rodrigo and Zheng, Jiamao and Wheeler, Heather E and Torres, Jason M and Torstenson, Eric S and Shah, Kaanan P and Garcia, Tzintzuni and Edwards, Todd L and Stahl, Eli A and Huckins, Laura M and Aguet, François and Ardlie, Kristin G and Cummings, Beryl B and Gelfand, Ellen T and Getz, Gad and Hadley, Kane and Handsaker, Robert E and Huang, Katherine H and Kashin, Seva and Karczewski, Konrad J and Lek, Monkol and Li, Xiao and MacArthur, Daniel G and Nedzel, Jared L and Nguyen, Duyen T and Noble, Michael S and Segrè, Ayellet V and Trowbridge, Casandra A and Tukiainen, Taru and Abell, Nathan S and Balliu, Brunilda and Barshir, Ruth and Basha, Omer and Battle, Alexis and Bogu, Gireesh K and Brown, Andrew and Brown, Christopher D and Castel, Stephane E and Chen, Lin S and Chiang, Colby and Conrad, Donald F and Damani, Farhan N and Davis, Joe R and Delaneau, Olivier and Dermitzakis, Emmanouil T and Engelhardt, Barbara E and Eskin, Eleazar and Ferreira, Pedro G and Frésard, Laure and Gamazon, Eric R and Garrido-Martín, Diego and Gewirtz, Ariel D. H and Gliner, Genna and Gloudemans, Michael J and Guigo, Roderic and Hall, Ira M and Han, Buhm and He, Yuan and Hormozdiari, Farhad and Howald, Cedric and Jo, Brian and Kang, Eun Yong and Kim, Yungil and Kim-Hellmuth, Sarah and Lappalainen, Tuuli and Li, Gen and Li, Xin and Liu, Boxiang and Mangul, Serghei and McCarthy, Mark I and McDowell, Ian C and Mohammadi, Pejman and Monlong, Jean and Montgomery, Stephen B and Muñoz-Aguirre, Manuel and Ndungu, Anne W and Nobel, Andrew B and Oliva, Meritxell and Ongen, Halit and Palowitch, John J and Panousis, Nikolaos and Papasaikas, Panagiotis and Park, YoSon and Parsana, Princy and Payne, Anthony J and Peterson, Christine B and Quan, Jie and Reverter, Ferran and Sabatti, Chiara and Saha, Ashis and Sammeth, Michael and Scott, Alexandra J and Shabalin, Andrey A and Sodaei, Reza and Stephens, Matthew and Stranger, Barbara E and Strober, Benjamin J and Sul, Jae Hoon and ... and GTEx Consortium
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1825 - 20
Journal Article
NATURE, ISSN 0028-0836, 05/2019, Volume 569, Issue 7754, pp. 66 - 66
Intestinal organoids are complex three-dimensional structures that mimic the cell-type composition and tissue organization of the intestine by recapitulating... 
PROGENITOR CELLS | VARIABILITY | POPULATION | STEM-CELLS | YAP/TAZ | MULTIDISCIPLINARY SCIENCES | NOTCH | YAP | Physiological aspects | Intestines | Symmetry (Biology) | Observations | Broken symmetry | Asymmetric structures | Activation | Paneth cells | Spheres | Gene expression | Yes-associated protein | Regeneration | DELTA protein | Organoids | Intestine | Transcription activation | Crypts | Stem cells | Symmetry
Journal Article
by Battle, Alexis and Brown, Christopher D and Engelhardt, Barbara E and Montgomery, Stephen B and Aguet, François and Ardlie, Kristin G and Cummings, Beryl B and Gelfand, Ellen T and Getz, Gad and Hadley, Kane and Handsaker, Robert E and Huang, Katherine H and Kashin, Seva and Karczewski, Konrad J and Lek, Monkol and Li, Xiao and MacArthur, Daniel G and Nedzel, Jared L and Nguyen, Duyen T and Noble, Michael S and Segrè, Ayellet V and Trowbridge, Casana A and Tukiainen, Taru and Abell, Nathan S and Balliu, Brunilda and Barshir, Ruth and Basha, Omer and Bogu, Gireesh K and Brown, Anew and Castel, Stephane E and Chen, Lin S and Chiang, Colby and Conrad, Donald F and Cox, Nancy J and Damani, Farhan N and Davis, Joe R and Delaneau, Olivier and Dermitzakis, Emmanouil T and Eskin, Eleazar and Ferreira, Peo G and Frésard, Laure and Gamazon, Eric R and Garrido-Martín, Diego and Gewirtz, Ariel D. H and Gliner, Genna and Gloudemans, Michael J and Guigo, Roderic and Hall, Ira M and Han, Buhm and He, Yuan and Hormozdiari, Farhad and Howald, Ceic and Kyung Im, Hae and Jo, Brian and Yong Kang, Eun and Kim, Yungil and Kim-Hellmuth, Sarah and Lappalainen, Tuuli and Li, Gen and Li, Xin and Liu, Boxiang and Mangul, Serghei and McCarthy, Mark I and McDowell, Ian C and Mohammadi, Pejman and Monlong, Jean and Muñoz-Aguirre, Manuel and Ndungu, Anne W and Nicolae, Dan L and Nobel, Anew B and Oliva, Meritxell and Ongen, Halit and Palowitch, John J and Panousis, Nikolaos and Papasaikas, Panagiotis and Park, Yoson and Parsana, Princy and Payne, Anthony J and Peterson, Christine B and Quan, Jie and Reverter, Ferran and Sabatti, Chiara and Saha, Ashis and Sammeth, Michael and Scott, Alexana J and Shabalin, Aney A and Sodaei, Reza and Stephens, Matthew and Stranger, Barbara E and Strober, Benjamin J and Sul, Jae Hoon and Tsang, Emily K and Urbut, Sarah and van de Bunt, Martijn and Wang, Gao and Wen, Xiaoquan and Wright, Fred A and Xi, Hualin S and Yeger-Lotem, Esti and Zappala, Zachary and ... and Pathology and Laboratory Data Analysis and Lab Data Anal Coordinating Ct and Stat Methods Grps-Anal Working Grp and Biospecimen Collection Source Sit and Genome Browser Data Integration and Biospecimen Core Resource-Vari and Leidos Biomedical-Project and Genome Browser Data Integr and Enhancing Gtex Egtex Grps and Gtex Consortium and Biospecimen Collection Source and Brain Bank Repository-Univ M and GTEx Consortium and Leidos Biomedical—Project Management and Laboratory, Data Analysis &Coordinating Center (LDACC) and NIH/NCI and Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group and Statistical Methods groups—Analysis Working Group and Biospecimen Collection Source Site—NDRI and NIH/NHGRI and Brain Bank Repository—University of Miami Brain Endowment Bank and Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz and NIH Common Fund and Enhancing GTEx (eGTEx) groups and NIH/NIMH and Genome Browser Data Integration &Visualization—EBI and Lead analysts and Biospecimen Collection Source Site—RPCI and Biospecimen collection and Biospecimen Core Resource—VARI and NIH program management and eQTL manuscript working group and ELSI Study and NIH/NIDA
Nature, ISSN 0028-0836, 2017, Volume 550, Issue 7675, pp. 204 - 213
Journal Article
Cell Reports, ISSN 2211-1247, 04/2019, Volume 27, Issue 3, pp. 847 - 859.e6
Alternative splicing is a prevalent mechanism of gene regulation that is modulated in response to a wide range of extracellular stimuli. Stress-activated... 
GADD45 | alternative splicing | stress responses | p38 SAPK | cell signaling | ACTIVATED PROTEIN-KINASE | INHIBITION | EMERGING ROLE | CHROMATIN | GENE | TRANSCRIPTION | MAP KINASES | HNRNP A1 | PROLIFERATION | STRESS | CELL BIOLOGY | Alternative splicing | Stress responses | Cell signaling
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2015, Volume 57, Issue 1, pp. 23 - 38
Journal Article