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The American Journal of Human Genetics, ISSN 0002-9297, 05/2009, Volume 84, Issue 5, pp. 617 - 627
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 06/2017, Volume 120, Issue 12, pp. 1903 - 1915
Journal Article
Journal Article
Science signaling, ISSN 1945-0877, 10/2015, Volume 8, Issue 399, pp. ra105 - ra105
Smooth muscle cells (SMCs) and the extracellular matrix (ECM) are intimately associated in the aortic wall. Fbln4(SMKO) mice with an SMC-specific deletion of... 
Actin Depolymerizing Factors - physiology | Mice | Animals | Disease Progression | Aortic Aneurysm - physiopathology | Index Medicus
Journal Article
SCIENCE SIGNALING, ISSN 1945-0877, 10/2015, Volume 8, Issue 399
Smooth muscle cells (SMCs) and the extracellular matrix (ECM) are intimately associated in the aortic wall. Fbln4(SMKO) mice with an SMC-specific deletion of... 
MIGRATION | ACTIN REORGANIZATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MARFAN-SYNDROME | PHENOTYPE | POSTNATAL-DEVELOPMENT | SMOOTH-MUSCLE-CELL | MUTATIONS | PHOSPHATASE SLINGSHOT | BLOOD-PRESSURE | CELL BIOLOGY
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 10/2015, Volume 24, Issue 20, pp. 5867 - 5879
Journal Article
The Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, 2008, Volume 136, Issue 4, pp. 922 - 929.e1
Objective This study sought to characterize the inflammatory infiltrate in ascending thoracic aortic aneurysm in patients with Marfan syndrome, familial... 
Cardiothoracic Surgery | SURGERY | VESSEL | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTAGONIST | RECEPTOR | LOCUS | GROWTH-FACTOR-BETA | INTERFERON-GAMMA | ARTERITIS | RESPIRATORY SYSTEM | DISEASE | DISSECTIONS | MUTATIONS | Immunohistochemistry | Antigens, CD - immunology | Multivariate Analysis | Aortic Aneurysm, Abdominal - immunology | Aortic Aneurysm, Abdominal - surgery | Humans | Marfan Syndrome - surgery | Middle Aged | Male | Reference Values | Case-Control Studies | Antigens, CD - metabolism | Transforming Growth Factor beta2 - immunology | Transforming Growth Factor beta2 - analysis | Aortic Aneurysm, Thoracic - pathology | Sensitivity and Specificity | Statistics, Nonparametric | Adult | Female | Receptors, Antigen, T-Cell - immunology | Aortic Aneurysm, Thoracic - immunology | Aortic Aneurysm, Abdominal - pathology | Vascular Cell Adhesion Molecule-1 - immunology | RNA - analysis | Receptors, Antigen, T-Cell - metabolism | Tissue Culture Techniques | Biomarkers - analysis | Antigens, Differentiation, T-Lymphocyte - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Marfan Syndrome - genetics | Antigens, Differentiation, T-Lymphocyte - genetics | Aortic Aneurysm, Thoracic - surgery | Marfan Syndrome - pathology | Aged | Cardiac Surgical Procedures - methods | Biopsy, Needle | Vascular Cell Adhesion Molecule-1 - metabolism | Polymerase chain reaction | Medical colleges | Care and treatment | Aneurysms | Genetic aspects | T cells | Marfan syndrome | Index Medicus | Abridged Index Medicus
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2013, Volume 5, Issue 183, pp. 183ra58, 1 - 183ra58
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 08/2013, Volume 22, Issue 15, pp. 3123 - 3137
Mutations in ACTA2, encoding the smooth muscle cell (SMC)-specific isoform of alpha -actin ( alpha -SMA), cause thoracic aortic aneurysms and dissections and... 
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2007, Volume 39, Issue 12, pp. 1488 - 1493
  The major function of vascular smooth muscle cells (SMCs) is contraction to regulate blood pressure and flow. SMC contractile force requires cyclic... 
Complications and side effects | Chest | Gene mutations | Actin | Genetic aspects | Research | Diagnosis | Risk factors | Diseases | Blood vessels | Aneurysms | Medical research | Mutation | Muscular system | Cells
Journal Article