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by Meade, T and Collins, R and Armitage, J and Parish, S and Barton, J and Bray, C and Wincott, E and Bowman, L and Clarke, R and Graham, I and Simpson, D and Warlow, C and Tobert, J and Musliner, T and Doll, R and Fox, K.M and Hill, C and Sandercock, P and Peto, R and Webster, J and Jamieson, J and Nixon, A and Lackie, S and Thompson, J and Brown, M and Blackwood, S and Morgan, M and Rhoden, W and Saeed, B and Houghton, M and Nicholson, A and Simpson, C and Hoburn, B and Cooper, I and Gallivan, A and Pickerell, E and Hancock, J and Watkinson, J and Burbridge, W and Kitchen, M and O'Leary, H and Verow, C and Meynell, L and Rollinson, L and Bain, S and Jones, A and Jewkes, C and Russon, C and Bateson, M and Gill, P and Stansbie, D and Bayly, G and Andrews, G and Halestrap, M and Meredith, J and Best, R and Appleyard, D and Wareing, H and Holmes, K and Holt, J and Kenyon, M and White, C and Khalifa, M and Newton, D and Wass, A and Watkinson, R and Creamer, J and Bethell, A and Butler, C and Washington, M and Weston, E and Machin, J and Cleaver, K and Wray, R and Sinclair, J and Van Aalst, A and Been, M and Mattu, R and Burke, A and Gill, L and Walton, E and Cowley, M and Robson, H and Graham, A and Rose, G and Kerr, M and Mallinson, J and Peascod, B and Scott, A and Donnelly, R and Gibson, T and Hannah, J and Henshaw, L and Margetts, M and Pearson, N and Frost, S and Murray, S and Marshall, A and Went, J and Simmonds, J and ... and The SEARCH Collaborative Group and SEARCH Collaborative Grp and SEARCH Collaborative Group and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The New England Journal of Medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 8, pp. 789 - 799
A genomewide screen of patients with myopathy who were taking high-dose simvastatin (80 mg per day) showed a strong association between myopathy and variants... 
MEDICINE, GENERAL & INTERNAL | POLYMORPHISMS | EFFICACY | SAFETY | TRANSPORTING POLYPEPTIDE 1B1 | SIMVASTATIN | CYP3A4 | ASSOCIATION | ATORVASTATIN | Simvastatin - therapeutic use | Simvastatin - adverse effects | Humans | Middle Aged | Diabetes Mellitus - drug therapy | Genotype | Male | Risk | Genetic Markers | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Myocardial Infarction - drug therapy | Arterial Occlusive Diseases - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Female | Aged | Myocardial Infarction - prevention & control | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 12 | Muscular Diseases - chemically induced | Muscular Diseases - genetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Complications and side effects | Analysis | Muscle diseases | Genetic aspects | Dosage and administration | Single nucleotide polymorphisms | Risk factors | Statins | Drug therapy | Kinases | Drug dosages | Cholesterol | Index Medicus | Abridged Index Medicus | MEDICIN OCH HÄLSOVETENSKAP | Single Nucleotide | genetics | Arterial Occlusive Diseases | pharmacokinetics | Muscular Diseases | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Chromosomes | MEDICAL AND HEALTH SCIENCES | Human | drug therapy | chemically induced | Simvastatin | prevention & control | Diabetes Mellitus | Myocardial Infarction | Pair 12 | Organic Anion Transporters | adverse effects | therapeutic use | Polymorphism
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9753, pp. 1658 - 1669
Journal Article
by Mihaylova, Borislave and Briggs, Andrew and Hlatky, Mark and Armitage, Jane and Parish, Sarah and Gray, Alastair and Collins, Rory and Collins, R and Meade, T and Sleight, P and Armitage, J and Parish, S and Peto, R and Youngman, L and Buxton, M and De Bono, D and George, C and Fuller, J and Keech, A and Mansfield, A and Pentecost, B and Simpson, D and Warlow, C and McNamara, J and O’Toole, L and Doll, R and Wilhelmsen, L and Fox, K.M and Hill, C and Sandercock, P and Benjamin, N and Webster, J and Jamieson, J and Donald, L and Blandford, R and Carrington, L and McMahon, H and Cheetham, D and Reckless, J and Brice, L and Carpenter, R and Christmas, J and Flower, C and Cooper, I and Frampton, S and Pickerell, E and Wells, J and Scott, M and Crowe, V and Shaw, A and Shannon, L and Jones, S and Faulkner, G and Lavery, A and O’Leary, H and Watson, R and Capewell, C and Hughes, S and Bain, S and Jones, A and Holmes, G and Jewkes, C and Bellamy, T and Harrison, P and Buller, N and Hooks, J and Jones, H and Smith, E and Vint, P and Crook, P and Williams, J and Bateson, M and Cawley, P and Gill, P and Hawkeswell, L and Simpson, K and Armitage, M and Cope, C and Tricksey, J and Wilson, M and Cottrell, S and Jones, C and Llewellyn, M and Smith, P and Woodsford, T and Vincent, R and Joyce, E and Skipper, N and Peters, P and Lemon, M and Stansbie, D and Hagos Kidan, A and Halestap, M and Gibbons, A and Meredith, J and Dawkins, C and Papouchado, M and Baker, L and Boulton, K and Dawe, C and ... and Heart Protection Study and Heart Protection Study Collaborative Group
Circulation: Cardiovascular Quality and Outcomes, ISSN 1941-7713, 2009, Volume 2, Issue 2, pp. 65 - 72
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56100
Journal Article
by Meade, T and Sleight, P and Collins, R and Armitage, J and Parish, S and Peto, R and Youngman, L and Buxton, M and de Bono, D and Fuller, J and Keech, A and Mansfield, A and Pentecost, B and Simpson, D and Warlow, C and O'Toole, L and Doll, R and Wilhelmsen, L and Fox, K and Hill, C and Sandercock, P and Barton, J and Bray, C and Jayne, K and Lawson, A and Harding, P and Lay, M and Wallendszus, K and Benjamin, N and Webster, J and Jamieson, J and Donald, L and Blandford, R and Carrington, L and McMahon, H and Cheetham, D and Reckless, J and Brice, L and Carpenter, R and Christmas, J and Flower, C and Cooper, I and Frampton, S and Pickerell, E and Wells, J and Scott, M and Crowe, V and Shaw, A and Shannon, L and Jones, S and Faulkner, G and Lavery, A and O'Leary, H and Watson, R and Capewell, C and Hughes, S and Bain, S and Jones, A and Holmes, G and Jewkes, C and Bellamy, T and Harrison, P and Buller, N and Nield, H and Smith, E and Vint, P and Crook, P and Williams, J and Bateson, M and Cawley, P and Gill, P and Simpson, K and Armitage, M and Cope, C and Tricksey, J and Wilson, M and Cottrell, S and Jones, C and Llewellyn, M and Smith, P and Woodsford, T and Vincent, R and Joyce, E and Skipper, N and Peters, P and Lemon, M and Stansbie, D and Kidan, AH and Halestrap, M and Gibbons, A and Meredith, J and Dawkins, C and Papouchado, M and Baker, L and Boulton, K and Dawe, C and Lewis, A and Wisby, J and Brown, M and Emeny, J and ... and MRC BHF Heart Study Collaborative Grp
EUROPEAN HEART JOURNAL, ISSN 0195-668X, 05/1999, Volume 20, Issue 10, pp. 725 - 741
Journal Article
by Armitage, Jane and Heart Protection Study Collaborative Group, Protection Study Collaborative Group and Collins, Rory and Bowman, Louise and Parish, Sarah and Sleight, Peter and Peto, Richard and Meade, T and Youngman, L and Buxton, M and de Bono, D and George, C and Fuller, J and Keech, A and Mansfield, A and Pentecost, B and Simpson, D and Warlow, C and McNamara, J and O'Toole, L and Benjamin, N and Webster, J and Jamieson, J and Donald, L and Blandford, R and Carrington, L and McMahon, H and Cheetham, D and Reckless, J and Brice, L and Carpenter, R and Christmas, J and Flower, C and Cooper, I and Frampton, S and Pickerell, E and Wells, J and Scott, M and Crowe, V and Shaw, A and Shannon, L and Jones, S and Faulkner, G and Lavery, A and O'Leary, H and Watson, R and Capewell, C and Hughes, S and Bain, S and Jones, A and Holmes, G and Jewkes, C and Bellamy, T and Harrison, P and Buller, N and Hooks, J and Jones, H and Smith, E and Vint, P and Watson, R and Crook, P and Williams, J and Bateson, M and Cawley, P and Gill, P and Hawkeswell, L and Simpson, K and Armitage, M and Cope, C and Tricksey, J and Wilson, M and Cottrell, S and Jones, C and Llewellyn, M and Smith, P and Woodsford, T and Vincent, R and Joyce, E and Skipper, N and Peters, P and Lemon, M and Stansbie, D and Kidan, A. Hagos and Halestap, M and Gibbons, A and Meredith, J and Dawkins, C and Papouchado, M and Baker, L and Boulton, K and Dawe, C and Lewis, A and Wisby, J and Brown, M and Emeny, J and Smith, W and Thurston, D and Trutwein, D and Cornwell, M and Lloyd, D and Heart Protection Study Collaborati and Heart Protection Study Collaborative Group
BMC Medicine, ISSN 1741-7015, 03/2005, Volume 3, Issue 1, pp. 6 - 6
Background: There have been concerns that low blood cholesterol concentrations may cause non-vascular mortality and morbidity. Randomisation of large numbers... 
MEDICINE, GENERAL & INTERNAL | Simvastatin - therapeutic use | Follow-Up Studies | Cholesterol - blood | Humans | Middle Aged | Mortality | Neoplasms - mortality | Male | United Kingdom | Diabetes Mellitus | Cause of Death | Vascular Diseases - mortality | Anticholesteremic Agents - therapeutic use | Aged, 80 and over | Adult | Cholesterol, LDL - blood | Female | Aged
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 6/2014, Volume 59, Issue 6, pp. 1197 - 1206
Journal Article