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International Journal of Molecular Sciences, ISSN 1422-0067, 10/2019, Volume 20, Issue 19, p. 4920
Brugada syndrome (BrS) is marked by an elevated ST-segment elevation and increased risk of sudden cardiac death. Variants in the SCN5A gene are considered to... 
mutation | Brugada syndrome | sodium channel | genetic testing | arrhythmia | channelopathy | sudden cardiac death | SCN5A | family | point-nonsense mutation
Journal Article
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, ISSN 1099-5129, 07/2019, Volume 21, Issue 10, pp. 1550 - 1558
The Brugada syndrome (BrS) is an inherited disease associated with an increased risk of sudden cardiac death. Often, the genetic cause remains undetected.... 
Journal Article
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, ISSN 1099-5129, 06/2019, Volume 21, Issue 10, pp. 1574 - 1574
Journal Article
09/2019
The local conduction velocity of a cardiac activation wavefront can be computed by collecting a plurality of electrophysiology ("EP") data points using a... 
SURGERY | DIAGNOSIS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | IDENTIFICATION
Patent
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, ISSN 1099-5129, 08/2019
To define the clinical characteristics and long-term clinical outcomes of a large cohort of patients with idiopathic ventricular fibrillation (IVF) and normal... 
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 08/2019, Volume 10, p. 986
Myocardial infarct requires prompt thrombolytic therapy or primary percutaneous coronary intervention to limit the extent of necrosis, but reperfusion creates... 
CARDIOMYOCYTE HYPERTROPHY | PHYSIOLOGY | sphingolipids | LIPOPROTEIN-LIPASE ACTIVITY | DOWN-REGULATION | RECEPTOR | myriocin | ischemia | HEART | ceramide | GENE-EXPRESSION | PERILIPIN 5 | PPAR-GAMMA | metabolism | ACCUMULATION | reperfusion | ADIPOSE-TISSUE | Ischemia | Lipids
Journal Article
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, ISSN 1099-5129, 05/2019, Volume 21, Issue 8, pp. 1193 - 1202
Clinical outcomes after radiofrequency catheter ablation (RFCA) remain suboptimal in the treatment of non-paroxysmal atrial fibrillation (AF).... 
Journal Article
Heart Rhythm, ISSN 1547-5271, 07/2019, Volume 16, Issue 7, pp. 1047 - 1056
Patient-specific programming of cardiac resynchronization therapy (CRT) is often neglected, despite significant nonresponse rates. The device-based SyncAV CRT... 
Heart failure | QRS duration | Cardiac resynchronization therapy | Optimization | Atrioventricular delay | CARDIAC & CARDIOVASCULAR SYSTEMS | PART | HEART-FAILURE | Cardiology | Algorithms | Electric properties
Journal Article
06/2019
A flexible tip electrode for an ablation catheter is disclosed. The catheter includes a catheter body and a hollow elongate tip electrode disposed at a distal... 
SURGERY | DIAGNOSIS | HYGIENE | METALLURGY | ORGANIC MACROMOLECULAR COMPOUNDS | CHEMISTRY | THEIR PREPARATION OR CHEMICAL WORKING-UP | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | IDENTIFICATION | COMPOSITIONS OF MACROMOLECULAR COMPOUNDS | COMPOSITIONS BASED THEREON
Patent
FRONTIERS IN GENETICS, ISSN 1664-8021, 06/2019, Volume 10, p. 547
In this case report, we characterize a novel inherited frameshift mutation c.4700_4701del (p.Phe1567Cysfs*221) in a single copy of the SCN5A gene and its... 
mutation | atrial fibrillation | GENETIC-BASIS | Brugada syndrome | sodium channel | genetic testing | arrhythmia | GENETICS & HEREDITY | sudden cardiac death | SCN5A | Tachycardia | Care and treatment | Genetic aspects | Medical research | Gene mutations | Medicine, Experimental | Research
Journal Article
Cardiac electrophysiology clinics, 06/2019, Volume 11, Issue 2, p. 345
Several acquired and congenital disease conditions and many cardiac and noncardiac drugs affect ventricular repolarization and increase susceptibility to... 
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 05/2019, Volume 10, p. 666
Brugada syndrome (BrS) is a known cause of sudden cardiac death. The genetic basis of BrS is not well understood, and no one single gene is linked to even a... 
PHYSIOLOGY | Brugada syndrome | sodium channel | genetic testing | arrhythmia | variant | RISK | COHORT | sudden cardiac death | SCN5A | MUTATIONS | cardiomyopathy
Journal Article
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN 1010-7940, 05/2019, Volume 55, Issue 5, pp. 845 - 850
Journal Article
JACC. Cardiovascular imaging, 03/2019
The aim of this study was to identify the pattern of exercise left atrial (LA) dynamics, its gas exchange correlates, and prognosis in mitral regurgitation... 
Journal Article
Arrhythmia and Electrophysiology Review, ISSN 2050-3369, 03/2019, Volume 8, Issue 1, pp. 13 - 18
Brugada syndrome (BrS) represents an inherited disorder associated with risk of sudden cardiac death due to VF in patients without structural heart disease.... 
Right ventricular outflow tract | Brugada syndrome | Catheter ablation | Ventricular tachycardia | Ajmaline | ICD | Arrhythmic substrate | Ventricular fibrillation | ventricular fibrillation | ajmaline | ventricular tachycardia | arrhythmic substrate | catheter ablation | Clinical Arrhythmias | right ventricular outflow tract
Journal Article
European Heart Journal Supplements, ISSN 1520-765X, 03/2019, Volume 21, Issue Supplement_B, pp. B61 - B66
Abstract Brugada syndrome (BrS) and several cardiomyopathies, including dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, left... 
CARDIAC & CARDIOVASCULAR SYSTEMS | Mapping | Brugada syndrome | Sudden cardiac death | Implantable cardioverter-defibrillator | Catheter ablation
Journal Article
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