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KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, ISSN 0023-2165, 03/2019, Volume 236, Issue 3, pp. 253 - 260
Hereditary retinal degenerative diseases are mostly diseases of the photoreceptors and/or the retinal pigment epithelium, which lead to loss of vision or even... 
cell death | DRUG-DELIVERY | MOUSE | cGMP | apoptosis | PIGMENTOSA | OUTER SEGMENTS | DEGENERATION | CHILDREN | EYE | IMPLANT | MUTANTS | MODELS | OPHTHALMOLOGY | blood-retinal-barrier
Journal Article
Cell Death and Disease, ISSN 2041-4889, 02/2010, Volume 1, Issue 2, pp. e24 - e24
Inherited retinal degenerations, collectively termed retinitis pigmentosa (RP), constitute one of the leading causes of blindness in the developed world. RP is... 
Neuroprotection | Retina | Trichostatin A | Epigenetic | Retinitis pigmentosa | Sirtuin | RETINAL DEGENERATION | SURVIVAL | POLY(ADP-RIBOSE) | PROTEIN | epigenetic | trichostatin A | ACETYLATION | TRANSCRIPTION | VALPROIC ACID | CELL BIOLOGY | PHOTORECEPTOR CELL-DEATH | sirtuin | retina | neuroprotection | retinitis pigmentosa | GENE-EXPRESSION | HISTONE DEACETYLASE INHIBITORS | Gene Expression Regulation, Enzymologic - drug effects | Nerve Degeneration - enzymology | Histone Deacetylases - genetics | Oligonucleotide Array Sequence Analysis | Isoenzymes - genetics | Humans | Photoreceptor Cells, Vertebrate - drug effects | Histone Deacetylases - metabolism | Enzyme Activation - drug effects | Nerve Degeneration - pathology | Photoreceptor Cells, Vertebrate - enzymology | Acetylation - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Animals | Isoenzymes - metabolism | Mice, Mutant Strains | Cytoprotection - drug effects | Histone Deacetylase Inhibitors - pharmacology | Mice | Cell Death - drug effects | Retinal Degeneration - pathology | Photoreceptor Cells, Vertebrate - pathology | Retinal Degeneration - enzymology | Original | pigmentosa | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell and Molecular Biology | retinitis | Medicinska och farmaceutiska grundvetenskaper | Cell- och molekylärbiologi
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 12/2008, Volume 38, Issue 3, pp. 253 - 269
Photoreceptor cell death is the major hallmark of a group of human inherited retinal degenerations commonly referred to as retinitis pigmentosa (RP). Although... 
rds | Oxidative stress | rd2 | Calcium | Neurobiology | Calpain | cGMP | Retina | PARP | Cell Biology | Life Sciences | Neurology | CREB | AIF | rd1 | CALCIUM-CHANNEL BLOCKER | APOPTOSIS-INDUCING FACTOR | NITRIC-OXIDE SYNTHASE | D-CIS-DILTIAZEM | ROD CGMP-PHOSPHODIESTERASE | ELEMENT-BINDING PROTEIN | ENDOPLASMIC-RETICULUM STRESS | NEUROSCIENCES | CAMP EARLY REPRESSOR | RD1 MOUSE RETINA | MEDIATED PROGRAMMED NECROSIS | Nucleotides, Cyclic - metabolism | Calpain - metabolism | Oxidative Stress | Calcium - metabolism | Retinal Degeneration - genetics | Humans | Retinitis Pigmentosa - metabolism | Transcription Factors - genetics | Retinal Degeneration - metabolism | Transcription Factors - metabolism | Cyclic AMP Response Element-Binding Protein - genetics | Endoplasmic Reticulum - pathology | Retinitis Pigmentosa - enzymology | Animals | DNA Fragmentation | Cell Death | Cyclic AMP Response Element-Binding Protein - metabolism | Mice | Photoreceptor Cells, Vertebrate - metabolism | Retinal Degeneration - pathology | Photoreceptor Cells, Vertebrate - pathology | Retinal Degeneration - enzymology | Retinitis Pigmentosa - pathology | Disease Models, Animal | Eye diseases | Apoptosis | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | REPRESSOR | Neurovetenskaper | Basic Medicine | CAMP EARLY | Medicinska och farmaceutiska grundvetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e112142
Journal Article
PLOS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6
Retinitis pigmentosa is an inherited blinding disorder characterized by progressive degeneration and loss of photoreceptors. The exact mechanism of... 
RETINAL DEGENERATION | RESCUE | MULTIDISCIPLINARY SCIENCES | CNG CHANNELS | MOUSE | RIBBON SYNAPSES | D-CIS-DILTIAZEM | INHIBITORS | RETINITIS-PIGMENTOSA | BLOCKER | SUBUNIT
Journal Article
Current Molecular Medicine, ISSN 1566-5240, 2012, Volume 12, Issue 5, pp. 598 - 612
Photoreceptor degeneration is the hallmark of several groups of inherited neurodegenerative diseases causing blindness in humans. These diseases are a major... 
Calpastatin | CGK | Epigenetics | Calpain | PARP | PKG | Apoptosis | HDAC | CALCIUM-CHANNEL BLOCKER | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | cGK | PROTEIN-KINASE-G | calpastatin | D-CIS-DILTIAZEM | epigenetics | CONE CELL-DEATH | NERVE GROWTH-FACTOR | calpain | EPITHELIUM-DERIVED FACTOR | RD1 MOUSE RETINA | CILIARY NEUROTROPHIC FACTOR | LEBERS CONGENITAL AMAUROSIS
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 02/2013, Volume 22, Issue 3, pp. 508 - 518
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 13, pp. E2997 - E3006
Journal Article
Investigative Ophthalmology & Visual Science, ISSN 0146-0404, 12/2009, Volume 50, Issue 12, pp. 5927 - 5933
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 2016, Volume 25, Issue 17, pp. 3729 - 3740
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2018, Volume 1074, pp. 367 - 373
Journal Article
GENES, ISSN 2073-4425, 06/2019, Volume 10, Issue 6, p. 453
Photoreceptor physiology and pathophysiology is intricately linked to guanosine-3',5'-cyclic monophosphate (cGMP)-signaling. Here, we discuss the importance of... 
CALCIUM-CHANNEL BLOCKER | RETINAL DEGENERATION | drug delivery systems | translational medicine | CANCER CELLS | PROTEIN-KINASE-G | cyclic GMP | RECESSIVE RETINITIS-PIGMENTOSA | apoptosis | D-CIS-DILTIAZEM | CELL-DEATH | CYCLIC-GMP | retina | necrosis | GENETICS & HEREDITY | NITRIC-OXIDE | GENE-THERAPY
Journal Article