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Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 9, pp. 1283 - 1294
Journal Article
by Peden, Carol and Peden, Carol J and Stephens, Tim and Martin, Michael and Martin, Graham and Kahan, Brennan and Kahan, Brennan C and Thomson, Ann and Rivett, Kate and Wells, Duncan and Wells, John and Richardson, Peter and Richardson, Gerry and Kerry, Sally and Bion, Julian and Pearse, Rupert M and Pearse, Rupert and Brett, Stephen and Ackland, Gareth and Grocott, Mike and Holt, Peter and Robert, Glenn and Ukoumunne, Obioha and Waring, Justin and Everingham, Kirsty and Phull, Mandeep and Cromwell, David and Evley, Rachel and Lilford, Richard and Kocman, David and Asaria, Miqdad and Tarrant, Carolyn and Yang, Fan and Abraham, Ajit and Bothma, Pieter and Conway, Daniel and Stapleton, Clare and Edwards, Jennifer and Edwards, Mark and Minto, Gary and Saunders, David and Owen, Tom and Waldmann, Carl and Hayden, Paul and Gillies, Michael and Tighe, Sean and Smith, Hannah and Smith, Neil and Mythen, Monty and Murray, Therese and Murray, Dave and Murray, Diane and Murray, David and Lobo, Dileep and Leuwer, Martin and Kirk-Bayley, Justin and Howell, Simon and Gordon, Anthony and Anderson, Iain and Lourtie, Jose and Walker, Simon and Drake, Sharon and Watson, Geoff and Watson, Nick and Watson, Nicholas and Watson, Mark and Szakmany, Tamas and Sutcliffe, Robert and Mahajan, Ravi and Girling, Alan and Forbes, Gordon and Faiz, Omar and Blunt, Mark and Singh, Jagdeep and Singh, Satish and Singh, Surjait and Steel, Alistair and Wong, Kate and Cabreros, Leilani and Chitre, Vivek and Obideyi, Ayodele and Ali, Dhiraj and Blenk, Karl and Broad, Dan and Brodbeck, Andreas and Dumpala, Rajesh and Engel, Arnth and Ganepola, Ranjit and Garg, Sudha and Gay, Mike and Karlikowsk, Michael and Lams, Edward and Millican, Dean and Misane, Inga and Mull, Ajaya and Naik, Veena and Pushpa, Nathan and Nutt, Chris and Sagadai, Saravanna and Stuart, Hazel and ... and Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group
The Lancet, ISSN 0140-6736, 06/2019, Volume 393, Issue 10187, pp. 2213 - 2221
Emergency abdominal surgery is associated with poor patient outcomes. We studied the effectiveness of a national quality improvement (QI) programme to... 
Intervention | Medical personnel | Abdominal surgery | Systemic diseases | Health | Decision making | Health services | Mortality | Health care policy | Critical care | Clinical trials | Emergency medical care | Survival | Patients | Clinical outcomes | Abdomen | Randomization | Hospitals | Motivation | Surgery | Quality control | Clusters | Emergency medical services | Quality of care
Journal Article
IEEE Transactions on Fuzzy Systems, ISSN 1063-6706, 10/2014, Volume 22, Issue 5, pp. 1229 - 1244
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 18002 - 10
Intratumoral genetic heterogeneity is a widely accepted characteristic of human cancer, including the most common primary malignant brain tumor, glioblastoma.... 
GLIOMA INVASION | MIGRATION | TYROSINE KINASE GENES | AMPLIFICATION | THERAPY | MRI | MULTIDISCIPLINARY SCIENCES | INTEGRATED GENOMIC ANALYSIS | MUTATION | MYOSIN-II | EGFR | Subpopulations | Epidermal growth factor receptors | Invasiveness | Brain tumors | Glioblastoma | Parenchyma | Gefitinib | Patients | Cell migration | Tumors | Cell adhesion & migration | Cancer
Journal Article
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2016, Volume 64, Issue 3, pp. 868 - 869
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 12
Among high-grade brain tumors, glioblastoma is particularly difficult to treat, in part due to its highly infiltrative nature which contributes to the... 
PROLIFERATION | CANCER | CELL-MIGRATION | MULTIDISCIPLINARY SCIENCES | GENES | MOTILITY | CRISPR | Phenotypes | Wound healing | Mesenchyme | Therapeutic applications | Brain tumors | Brain cancer | Glioblastoma | MAP kinase | Kinases | Glioma | Protein kinase | Cell lines
Journal Article