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Journal of Medical Genetics, ISSN 0022-2593, 10/2015, Volume 53, Issue 2, pp. 98 - 110
Journal Article
PLoS Genetics, ISSN 1553-7390, 01/2014, Volume 10, Issue 1, pp. e1004118 - e1004118
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2015, Volume 11, Issue 7, pp. e1005368 - e1005368
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62274 - e62274
Retinoic acid (RA), an active derivative of the liposoluble vitamin A (retinol), acts as an important signaling molecule during embryonic development,... 
MOUSE DEVELOPMENT | RESPONSE ELEMENT | NEURAL STEM-CELLS | NERVOUS-SYSTEM | RETINALDEHYDE DEHYDROGENASE | MOTIF OVER-REPRESENTATION | VERTEBRATE BODY AXIS | MULTIDISCIPLINARY SCIENCES | NUCLEAR RECEPTOR TLX | NEURONAL DIFFERENTIATION | POSTIMPLANTATION DEVELOPMENT | Embryonic Stem Cells - metabolism | Reproducibility of Results | Signal Transduction | Regulatory Sequences, Nucleic Acid | Computational Biology | Gene Expression Regulation, Developmental - drug effects | Gene Expression Profiling | Aldehyde Oxidoreductases - genetics | Cell Lineage - drug effects | Embryo, Mammalian - metabolism | Mice, Knockout | Pregnancy | Phenotype | Animals | Embryonic Stem Cells - drug effects | Tretinoin - metabolism | Female | Mice | Cell Lineage - genetics | Cluster Analysis | Tretinoin - pharmacology | Embryonic development | Vitamin A deficiency | Research | Genetic transcription | TOR protein | Cluster analysis | Pattern formation | Spinal cord | Transcription factors | Dehydrogenases | Transcription | Calcium | Arches | Genomics | Genes | Forebrain | Calcium metabolism | Genomes | Tissues | Calcium signalling | Signal transduction | Receptors | Embryogenesis | Retinaldehyde dehydrogenase 2 | Foxg1 protein | Carotenoids | Pathways | Repressors | Rodents | Vascular endothelial growth factor | Deoxyribonucleic acid--DNA | ILK protein | Enzymes | Developmental biology | Abnormalities | HOXA1 protein | Somitogenesis | Retinaldehyde | Gene expression | Nuclear receptors | Metabolism | Embryos | Pharynx | Embryonic growth stage | DNA microarrays | Acids | Retinaldehyde dehydrogenase | Stem cells | Hindbrain | Ligands | Retinoic acid | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e32447 - e32447
Studies in avian models have demonstrated an involvement of retinoid signaling in early neural tube patterning. The roles of this signaling pathway at later... 
MOTOR-NEURONS | PROGENITOR CELLS | NEURITE OUTGROWTH | SONIC HEDGEHOG | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | VERTEBRATE NEURAL-TUBE | DORSAL-ROOT GANGLIA | RETINALDEHYDE DEHYDROGENASE-2 | NEUROGENIN2 EXPRESSION | NERVE GROWTH-FACTOR | Nestin | Spinal Cord - metabolism | Signal Transduction | Receptors, Notch - metabolism | Intermediate Filament Proteins - biosynthesis | Mice, Transgenic | Aldehyde Oxidoreductases - genetics | Neural Stem Cells - cytology | Aldehyde Oxidoreductases - metabolism | Cell Lineage | Fibroblast Growth Factors - metabolism | Spinal Cord - embryology | Phenotype | Tubulin - metabolism | Animals | Tretinoin - metabolism | Nerve Tissue Proteins - biosynthesis | Transcription, Genetic | Cell Differentiation | Mice | Mutation | Spinal Cord - cytology | Ganglia, Spinal - metabolism | Fibroblast growth factors | Cell differentiation | Intermediate filament proteins | Analysis | Stem cells | Tretinoin | Pattern formation | Pediatrics | Fibroblast growth factor | Spinal cord | Animal models | Wnt protein | Differentiation (biology) | Stem cell transplantation | Alcohol | Lethality | Gestation | Vitamin A | Signal transduction | Neural tube | Tubulin | Allografts | Rodents | Neurospheres | Birth defects | Gene expression | Embryos | Mutants | Medicine | Signaling | Brain research | Acids | Neural stem cells | Notch protein | Alzheimers disease | Retinoic acid | Pluripotency | Apoptosis | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 03/2019, Volume 28, Issue 6, pp. 877 - 887
Abstract Acrocallosal syndrome (ACLS) is a rare genetic disorder characterized by agenesis or hypoplasia of corpus callosum (CC), polydactyly, craniofacial... 
MUTANT | DEFECTS | GENE | CORPUS-CALLOSUM FORMATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | PLANAR CELL POLARITY | MUTATIONS | EXPRESSION | SONIC-HEDGEHOG | PRIMARY CILIA | MIDLINE
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e84343 - e84343
Background: The RSK2 gene is responsible for Coffin-Lowry syndrome, an X-linked dominant genetic disorder causing mental retardation, skeletal growth delays,... 
MORPHOGENESIS | IN-VITRO | RETINOIC ACID | TOOTH DEVELOPMENT | COFFIN-LOWRY-SYNDROME | MULTIDISCIPLINARY SCIENCES | MOUSE MOLAR | RIBOSOMAL S6 KINASE | KAPPA-B-ALPHA | SPROUTY GENES | TABBY/EDA MICE | Abnormalities, Multiple - pathology | RNA, Small Interfering - genetics | Ribosomal Protein S6 Kinases, 90-kDa - deficiency | Male | Tooth - growth & development | Gene Expression Profiling | Head - growth & development | Craniofacial Abnormalities - physiopathology | Tooth - anatomy & histology | Abnormalities, Multiple - physiopathology | Gene Knockdown Techniques | MAP Kinase Signaling System | Odontogenesis | Phenotype | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Craniofacial Abnormalities - enzymology | Gene Expression Regulation, Developmental | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Abnormalities, Multiple - enzymology | Craniofacial Abnormalities - pathology | Mice | Enzyme Activation | Mental illness | Genetic aspects | DNA microarrays | Bioengineering | Pattern formation | Nuclear medicine | Phosphorylation | Transcription factors | Transcription | Mesenchyme | Genes | Molars | Kinases | Coffin-Lowry syndrome | Maxilla | Defects | Morphogenesis | Proteins | Biomedical materials | Etiology | Cell cycle | Deoxyribonucleic acid--DNA | Mandible | Medical imaging | Abnormalities | Teeth | Craniofacial syndromes | Biophysics | Dentistry | Gene expression | Neural crest | Mutants | Hereditary diseases | Ribosomal protein S6 kinase | Craniofacial growth | Cellular biology | Anomalies | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2015, Volume 11, Issue 7
  Spermatogenesis consists broadly of three phases: proliferation of diploid germ cells, meiosis, and finally extensive differentiation of the haploid cells... 
Transcription factors | Ontology | Sperm | Spermatogenesis | Rodents | Mutation | Gene expression | Arrests | Cell adhesion & migration | Defects
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 02/2016, Volume 53, Issue 2, p. 98
This appears to be the first report of the isolation of a penicillinase-producing strain of Neisseria gonorrhoeae in the Netherlands. The presence of a... 
Journal Article