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Nature Neuroscience, ISSN 1097-6256, 11/2010, Volume 13, Issue 11, pp. 1396 - 1403
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 13, pp. 5074 - 5079
Journal Article
Neuron, ISSN 0896-6273, 12/2014, Volume 84, Issue 6, pp. 1213 - 1225
Expanded GGGGCC (G4C2) nucleotide repeats within the C9ORF72 gene are the most common genetic mutation associated with both amyotrophic lateral sclerosis (ALS)... 
Journal Article
Journal Article
2006, 2nd ed., ISBN 9781841844633, xxi, 370
Book
Neuron, ISSN 0896-6273, 12/2014, Volume 84, Issue 6, pp. 1213 - 1225
Journal Article
Glia, ISSN 0894-1491, 08/2016, Volume 64, Issue 8, pp. 1298 - 1313
The efficacy of drugs targeting the CNS is influenced by their limited brain access, which can lead to complete pharmacoresistance. Recently a tissue‐specific... 
mutant SOD1 | endothelial cells | P‐glycoprotein | blood–brain barrier | amyotrophic lateral sclerosis | P-glycoprotein | Amyotrophic lateral sclerosis | Blood-brain barrier | Mutant SOD1 | Endothelial cells | blood-brain barrier | OXIDATIVE STRESS | MODEL | NEUROSCIENCES | SPORADIC ALS | DRUG EFFLUX TRANSPORTERS | PLURIPOTENT STEM-CELLS | IN-VITRO | MOTOR-NEURON DEGENERATION | DISEASE | MICE | EXPRESSION | Up-Regulation | Spinal Cord - metabolism | Capillaries - pathology | Coculture Techniques | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Astrocytes - pathology | NF-kappa B - metabolism | Spinal Cord - pathology | Superoxide Dismutase-1 - metabolism | Capillaries - metabolism | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | Cell Line | Endothelial Cells - metabolism | Mice, Transgenic | RNA-Binding Protein FUS - metabolism | Blood-Brain Barrier - metabolism | Blood-Brain Barrier - pathology | Amyotrophic Lateral Sclerosis - pathology | Animals | Amyotrophic Lateral Sclerosis - metabolism | Superoxide Dismutase-1 - genetics | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Astrocytes - metabolism | Drug resistance in microorganisms | Nervous system diseases | Gene mutations | Neurons | Analysis | Superoxide | Endothelium | Glycoproteins | Index Medicus
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 4/2016, Volume 131, Issue 4, pp. 605 - 620
Amyotrophic lateral sclerosis is characterized by progressive loss of motor neurons in the brain and spinal cord. Mutations in several genes, including FUS,... 
Neurosciences | Primary motor neurons | FUS | ALS | Amyotrophic lateral sclerosis | RNA-binding proteins | Stress granules | Pathology | Medicine & Public Health | Motor neuron diseases | Neurodegeneration | TDP-43 | Pur-alpha | C9orf72 | PRION-LIKE DOMAINS | DROSOPHILA MODEL | AMYOTROPHIC-LATERAL-SCLEROSIS | SINGLE-STRANDED-DNA | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | MEDIATED NEURODEGENERATION | MESSENGER-RNA | ALS-ASSOCIATED MUTATION | NUCLEAR FACTOR TDP-43 | CFTR EXON-9 | Arsenites - pharmacology | RNA, Small Interfering - genetics | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Humans | Male | DNA-Binding Proteins - metabolism | Poly-ADP-Ribose Binding Proteins | RNA Helicases | Cytoplasmic Granules - metabolism | Female | RNA Recognition Motif Proteins | Brain - cytology | Gene Expression Regulation - genetics | Cytoplasmic Granules - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | RNA-Binding Protein FUS - genetics | Rats | RNA-Binding Protein FUS - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Sodium Compounds - pharmacology | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Motor Neurons - metabolism | Transcription Factors - metabolism | Amyotrophic Lateral Sclerosis - pathology | DNA Helicases | Animals | Carrier Proteins - metabolism | Doxycycline - pharmacology | Anti-Bacterial Agents - pharmacology | RNA, Small Interfering - metabolism | RNA | Binding proteins | Cells | Neurophysiology | Protein binding | Index Medicus | primary motor neurons | neurodegeneration | amyotrophic lateral sclerosis | RNA binding proteins
Journal Article