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Nature Biotechnology, ISSN 1087-0156, 09/2013, Volume 31, Issue 9, pp. 839 - 843
The RNA-programmable Cas9 endonuclease cleaves double-stranded DNA at sites complementary to a 20-base-pair guide RNA. The Cas9 system has been used to modify... 
CRISPR | CELLS | IMMUNITY | ENDONUCLEASE | TALENS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SEQUENCE | GENE DISRUPTION | SYSTEMS | ZINC-FINGER NUCLEASES | RNA sequencing | Research | Nucleotide sequencing | Gene expression | DNA sequencing | Enzymes | Genetic engineering | Ribonucleic acid--RNA | Genomics | Deoxyribonucleic acid--DNA
Journal Article
Nature Methods, ISSN 1548-7091, 09/2011, Volume 8, Issue 9, pp. 765 - 772
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 05/2015, Volume 11, Issue 5, pp. 316 - 318
Directly modulating the activity of genome-editing proteins has the potential to increase their specificity by reducing activity following target locus... 
NUCLEASE SPECIFICITY | RNA | NICKASES | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLEAVAGE | DIRECTED EVOLUTION | MAMMALIAN-CELLS | DELIVERY | INTEIN
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 11/2016, Volume 7, Issue 2016, p. 1634
The rapid strides in molecular marker technologies followed by genomics, and next generation sequencing advancements in three major crops (rice, maize and... 
Transgenics | Association mapping | Genomics | Marker assisted selection | Transcriptome | Millets | Blast resistance | Genetic aspects | Research | Millet | Plant genetics | marker assisted selection | transgenics
Journal Article
Human Immunology, ISSN 0198-8859, 10/2018, Volume 79, pp. 159 - 159
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.humimm.2018.07.189... 
Viral antibodies | Antibodies | Transplantation | Kidneys | Medical screening | Analysis
Journal Article
Nature Methods, ISSN 1548-7091, 04/2018, Volume 15, Issue 4, pp. 238 - 239
Journal Article
Nature chemical biology, 05/2015, Volume 11, Issue 5, p. 316
Journal Article
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, ISSN 1058-4838, 05/2019
Anaplasmosis presents with fever, headache, and laboratory abnormalities including leukopenia and thrombocytopenia. Polymerase chain reaction (PCR) is the... 
Journal Article
Nature, ISSN 0028-0836, 1/2016, Volume 529, Issue 7587, pp. 490 - 495
CRISPR-Cas9 nucleases are widely used for genome editing but can induce unwanted off-target mutations. Existing strategies for reducing genome-wide off-targets... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2006, Volume 128, Issue 7, pp. 2477 - 2484
The laboratory evolution of enzymes with tailor-made DNA cleavage specificities would represent new tools for manipulating genomes and may enhance our... 
SITE | RECOMBINASE | MUTAGENESIS | PROTEIN | RECOGNITION | DNA | SELECTION | CLEAVAGE | BINDING | CHEMISTRY, MULTIDISCIPLINARY | PLASTICITY | Enzymes | Chemical properties | Nucleotide sequence | Structure
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 10/2013, Volume 41, Issue 19, pp. e181 - e181
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2016, Volume 24, pp. S288 - S288
Journal Article
Open Forum Infectious Diseases, ISSN 2328-8957, 11/2018, Volume 5, Issue suppl_1, pp. S578 - S578
Journal Article
RNA, ISSN 1355-8382, 4/2008, Volume 14, Issue 4, pp. 657 - 665
We developed self-quenching reporter molecules (SQRMs), oligodeoxynucleotides with fluorophore and quencher moieties at the 5′ and 3′ ends respectively, to... 
oligodeoxynucleotides | RNA silencing | Report | fluorescent probes | structure
Journal Article
RNA, ISSN 1355-8382, 04/2008, Volume 14, Issue 4, pp. 657 - 665
We developed self-quenching reporter molecules (SQRMs), oligodeoxynucleotides with fluorophore and quencher moieties at the 5' and 3' ends respectively, to... 
Journal Article
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