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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2092 - 18
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 2, pp. 136 - 143
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2497 - 2509
Journal Article
Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, pp. 7629 - 7629
Bile acids are signalling molecules, which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex bile acids in... 
GLP-1 SECRETION | FXR | BILE-ACID RECEPTORS | GLUCOSE-HOMEOSTASIS | OBESITY | MULTIDISCIPLINARY SCIENCES | RAT SMALL-INTESTINE | MICE | TYPE-2 DIABETES-MELLITUS | METABOLIC-RATE | EXPRESSION | Colon - cytology | Intestinal Mucosa - metabolism | Sequestering Agents - pharmacology | Humans | Ileum - metabolism | RNA, Messenger - metabolism | Colesevelam Hydrochloride - pharmacology | Obesity - genetics | Glucagon-Like Peptide 1 - genetics | Jejunum - metabolism | Insulin-Secreting Cells - metabolism | Proglucagon - drug effects | Diet, High-Fat | Jejunum - cytology | Enteroendocrine Cells - metabolism | Ileum - cytology | Proglucagon - metabolism | Insulin Secretion | Glucagon-Like Peptide 1 - metabolism | Signal Transduction | Bile Acids and Salts - metabolism | Nuclear Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Colon - metabolism | Mice, Knockout | Obesity - metabolism | Transcription Factors - metabolism | Insulin - metabolism | Animals | Glycolysis | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice, Obese | Mice | Proglucagon - genetics | Receptors, G-Protein-Coupled - genetics | Blood Glucose - metabolism | Anticholesteremic Agents - pharmacology | Intestines - cytology | Index Medicus | Cell and Molecular Biology | Endokrinologi och diabetes | Multidisciplinary Sciences | Cell- och molekylärbiologi | Endocrinology and Diabetes
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2015, Volume 21, Issue 5, pp. 512 - 517
Journal Article
BMJ, ISSN 0959-8138, 1/2012, Volume 344, Issue 7843, pp. 19 - 19
Journal Article
Journal Article
CLIN Journal, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1037 - 1051
The nuclear bile acid receptor farnesoid X receptor (FXR) is an important transcriptional regulator of bile acid, lipid, and glucose metabolism. FXR is highly... 
OBSTRUCTIVE CHOLESTASIS | MEDICINE, RESEARCH & EXPERIMENTAL | TRANSCRIPTIONAL ACTIVITY | GLUCOSE-HOMEOSTASIS | ACTIVATED PROTEIN-KINASE | LIVER-INJURY | FARNESOID-X-RECEPTOR | POSTTRANSLATIONAL MODIFICATIONS | MICE | CELLULAR-ENERGY | ORPHAN NUCLEAR RECEPTOR | Intestines - drug effects | Liver - pathology | Phosphorylation | Humans | Transcriptional Activation - drug effects | Homeostasis | Molecular Sequence Data | Male | Intestines - metabolism | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Biological Transport | Liver - drug effects | Adenylate Kinase - metabolism | Receptors, Cytoplasmic and Nuclear - chemistry | Transcription, Genetic | Caco-2 Cells | Amino Acid Sequence | Promoter Regions, Genetic | Bile Acids and Salts - biosynthesis | Signal Transduction | Cholestasis, Intrahepatic - pathology | Liver - metabolism | Metformin - pharmacology | Mice, Inbred C57BL | Hep G2 Cells | Hypoglycemic Agents - pharmacology | Cholestasis, Intrahepatic - metabolism | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Protein Binding | Adenylate Kinase - antagonists & inhibitors | Trans-Activators - metabolism | Mice | Protein Processing, Post-Translational | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological research | Transcription factors | Metformin | Research | Properties | Proteins | Biometrics | Rodents | Gallbladder diseases | Ligands | Experiments | Mass spectrometry | Cholesterol | Bile | Index Medicus | Abridged Index Medicus
Journal Article
by Saxena, Richa and Hivert, Marie-France and Langenberg, Claudia and Tanaka, Toshiko and Pankow, James and Vollenweider, Peter and Lyssenko, Valeriya and Bouatia-Naji, Nabila and Dupuis, Josée and Jackson, Anne and Kao, Wen and Li, Man and Glazer, Nicole and Manning, Alisa and Anluan, Jian and Stringham, Heather and Prokopenko, Inga and Johnson, Toby and Grarup, Niels and Boesgaard, Trine and Lecoeur, Cécile and Shrader, Peter and O´Connell, J.R and Ingelsson, Erik and Couper, David and Rice, Kenneth and Song, Kijoung and Aneasen, Camilla and Dina, Christian and Köttgen, Anna and Bacquer, Olivier and Pattou, François and Taneera, Jalal and Steinthorsdottir, Valgerdur and Rybin, Denis and Ardlie, Kristin and Sampson, Michael and Qi, Lu and Hoek, M.V and Weedon, Michael and Aulchenko, Yurii and Voight, Benjamin and Grallert, Harald and Balkau, Beverley and Bergman, Richard and Bielinski, Suzette and Bonnefond, Amélie and Bonnycastle, Lori and Borch-Johnsen, K and Böttcher, Yvonne and Brunner, Eric and Buchanan, Thomas and Bumpstead, Suzannah and Cavalcanti-Proença, Christine and Charpentier, Guillaume and Chen, Chao and Chines, Peter and Collins, Francis and Cornelis, Marilyn and Crawford, Gabe and Delplanque, Jerome and Doney, Alex and Egan, Josephine and Erdos, Michael and Firmann, Mathieu and Forouhi, Nita and Fox, Caroline and Goodarzi, Mark and Graessler, Jürgen and Hingorani, Aroon and Isomaa, Bo and Jørgensen, Torben and Kivimaki, Mika and Kovacs, Peter and Krohn, Knut and Kumari, Meena and Lauritzen, Torsten and Lévy-Marchal, Claire and Mayor, Vladimir and McAteer, Jarred and Meyre, David and Mitchell, Braxton and Mohlke, Karen and Morken, Mario and Narisu, Narisu and Palmer, Colin and Pakyz, Ruth and Pascoe, Laura and Payne, Felicity and Pearson, Daniel and Rathmann, Wolfgang and Sandbaek, Annelli and Sayer, A.A and Scott, Laura and Sharp, Stephen and Sijbrands, Eric and Singleton, Anew and Siscovick, David and Smith, Nicholas and Sparsø, Thomas and ... and GIANT Consortium and MAGIC Investigators and GIANT consortium and MAGIC investigators and the MAGIC investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Molekylär medicin and Geriatrik and Uppsala universitet and Institutionen för medicinska vetenskaper and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 02/2010, Volume 42, Issue 2, pp. 142 - 148
Journal Article