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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2015, Volume 112, Issue 11, pp. E1307 - E1316
The synthesis and processing of mRNA, from transcription to translation initiation, often requires splicing of intragenic material. The final mRNA composition... 
CLK1 | Alternative splicing | Ewing sarcoma | TERT | EWS-FLI1 | RNA-POLYMERASE-II | PATHWAYS | DNA-BINDING | SR PROTEIN | alternative splicing | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | TARGET GENES | TELOMERASE REVERSE-TRANSCRIPTASE | EXPRESSION | HELICASE | Oncogene Proteins, Fusion - metabolism | Humans | Sarcoma, Ewing - pathology | RNA, Messenger - metabolism | Spliceosomes - metabolism | Protein Isoforms - metabolism | Proto-Oncogene Protein c-fli-1 - metabolism | Base Sequence | Protein Binding - drug effects | Telomerase - metabolism | Indoles | Introns - genetics | Proto-Oncogene Protein c-fli-1 - genetics | RNA Processing, Post-Transcriptional - drug effects | Alternative Splicing - genetics | RNA, Messenger - genetics | RNA-Binding Protein EWS - genetics | Exons - genetics | Signal Transduction - genetics | RNA-Binding Protein EWS - metabolism | Alternative Splicing - drug effects | RNA Processing, Post-Transcriptional - genetics | Signal Transduction - drug effects | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Sarcoma, Ewing - genetics | Spliceosomes - drug effects | Physiological aspects | Development and progression | Messenger RNA | Research | Tumor proteins | Ewing's sarcoma | Proteins | Tumorigenesis | Ribonucleic acid--RNA | Telomerase | Genes | Stem cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2010, Volume 30, Issue 5, pp. 1217 - 1230
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 07/2011, Volume 18, Issue 7, pp. 761 - 768
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2018, Volume 50, Issue 6, pp. 814 - 824
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e78190 - e78190
The anti-cancer drug camptothecin inhibits replication and transcription by trapping DNA topoisomerase I (Top1) covalently to DNA in a "cleavable complex". To... 
RNA-POLYMERASE-II | CELLS | REPAIR | INITIATION | ELONGATION | MULTIDISCIPLINARY SCIENCES | CLEAVABLE COMPLEXES | DOUBLE-STRAND BREAKS | DNA TOPOISOMERASE-I | DAMAGE | DRUG CAMPTOTHECIN | DNA Topoisomerases, Type I - metabolism | Gene Library | Humans | Genome - genetics | Molecular Sequence Data | Genome - drug effects | Sequence Analysis, DNA | Transcription Elongation, Genetic - drug effects | DNA Helicases - metabolism | Poly-ADP-Ribose Binding Proteins | Base Sequence | DNA Repair Enzymes - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | Camptothecin - pharmacology | Fibroblasts - metabolism | Care and treatment | RNA | Genes | Genomics | DNA topoisomerase I | Genomes | B cells | Genetic transcription | Antineoplastic agents | RNA polymerases | Antimitotic agents | Synthesis | Analysis | DNA | Genetic aspects | Drug therapy | Tumor proteins | Cancer | Cockayne syndrome | Camptothecin | Health sciences | Transcription elongation | p53 Protein | Oncology | Kinases | Cancer therapies | Recovery | Transcription-coupled repair | Defects | Anticancer properties | T-cell receptor | Transcription termination | Poisons | Fibroblasts | Lesions | Repair | Bioinformatics | Elongation | Public health | Deoxyribonucleic acid--DNA | Environmental health | DNA topoisomerase | Gene expression | Ribonucleic acids | Combinatorial analysis | Apoptosis | Proto-oncogenes | Index Medicus | Deoxyribonucleic acid
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2005, Volume 209, Issue 1, pp. 1 - 9
Journal Article
Journal Article