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Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2016, Volume 92, pp. 100 - 109
Familial Cerebral Cavernous Malformation type 1 (CCM1) is an autosomal dominant disease caused by mutations in the Krev Interaction Trapped 1 gene, and... 
Disease severity | Oxidative stress | Free radicals | Cerebral Cavernous Malformation (CCM) | Familial Cerebral Cavernous Malformation type 1 | Vascular brain lesions | Reactive oxygen species (ROS) | Matrix metalloproteinase (MMP) | Genetic markers set association study | Intracerebral hemorrhage | KRIT1/CCM1 | Inter-individual variability in disease susceptibility and outcome | Cytochrome P450 (CYP) | Cerebrovascular disease | EET epoxyeicosatrienoic acids | 1,25-dihydroxyvitamin D3 | 24-OHC 24(S)-hydroxycholesterol | SNP single nucleotide polymorphism | 25-hydroxyvitamin D3 | AA arachidonic acid | ICH intracerebral hemorrhage | Abbreviations CCM Cerebral Cavernous Malformation | LT leukotrienes | CYP cytochrome P450 | ROS reactive oxygen species | ECM extracellular matrix | 27-OHC 27-hydroxycholesterol | BBB blood-brain barrier | PG prostaglandins | 1,25-OH | NVU neurovascular unit | MMP matrix metalloproteinase | 25-OH-D | CHM common hispanic mutation | VITAMIN-D | SIGNALING PATHWAYS | REDUCES OXIDATIVE STRESS | CEREBROVASCULAR-DISEASE | WHITE-MATTER LESIONS | ENDOCRINOLOGY & METABOLISM | MEDIATED REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BLOOD-BRAIN-BARRIER | CHOLESTEROL 24-HYDROXYLASE | CORONARY-ARTERY-DISEASE | Brain - diagnostic imaging | Matrix Metalloproteinases - genetics | KRIT1 Protein | Microtubule-Associated Proteins - genetics | Humans | Middle Aged | Male | Hemangioma, Cavernous, Central Nervous System - genetics | Brain - metabolism | Adult | Female | Multigene Family - genetics | Severity of Illness Index | Hemangioma, Cavernous, Central Nervous System - diagnostic imaging | Oxidative Stress - genetics | Genotype | Proto-Oncogene Proteins - genetics | Magnetic Resonance Imaging | Phenotype | Hemangioma, Cavernous, Central Nervous System - pathology | Brain - pathology | Cytochrome P-450 Enzyme System - genetics | Heterozygote | Aged | Polymorphism, Single Nucleotide | Mutation | Brain | Genetic markers | Analysis | Pharmacy | Cytochrome P-450 | Genetic research | Drugstores | Brain damage | Epidemiology | ECM, extracellular matrix | 27-OHC, 27-hydroxycholesterol | 25-OH-D3, 25-hydroxyvitamin D3 | CHM, common hispanic mutation | NVU, neurovascular unit | ICH, intracerebral hemorrhage | PG, prostaglandins | CCM, Cerebral Cavernous Malformation | KRIT1 | ROS, reactive oxygen species | CYP, cytochrome P450 | EET, epoxyeicosatrienoic acids | LT, leukotrienes | Original Contribution | BBB, blood–brain barrier | SNP, single nucleotide polymorphism | AA, arachidonic acid | 24-OHC, 24(S)-hydroxycholesterol | 1,25-OH2-D3, 1,25-dihydroxyvitamin D3 | CCM1 | MMP, matrix metalloproteinase
Journal Article
Cerebrovascular Diseases, ISSN 1015-9770, 01/2015, Volume 38, Issue 6, pp. 433 - 440
Journal Article
Stroke, ISSN 0039-2499, 01/2014, Volume 45, Issue 1, pp. 2 - 3
Journal Article
Journal Article
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 141, Issue 5, pp. 1160 - 1169
Journal Article
JOURNAL OF NEUROSURGERY, ISSN 0022-3085, 04/2019, Volume 130, Issue 4, pp. 1346 - 1350
OBJECTIVE The pathogenesis of dural arteriovenous fistulas (DAVFs) remains poorly defined. Prior studies on thrombophilia as a risk factor for DAVF development... 
SURGERY | RISK-FACTORS | MANAGEMENT | dural arteriovenous fistula | SINUS | THROMBOSIS | MTHFR | PREVALENCE | prothrombin | vascular disorders | CLINICAL NEUROLOGY | thrombophilia | factor V Leiden | WOMEN | FACTOR-V-LEIDEN | VENOUS THROMBOEMBOLISM | MUTATION | MALFORMATION
Journal Article
Cerebrovascular Diseases, ISSN 1015-9770, 01/2014, Volume 37, Issue 1, pp. 57 - 63
Journal Article