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Cancer Research, ISSN 0008-5472, 11/2015, Volume 75, Issue 22 Supplement 2, pp. IA24 - IA24
Journal Article
Science, ISSN 0036-8075, 5/2011, Volume 332, Issue 6030, pp. 687 - 696
Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell "mass cytometry" to examine healthy human... 
T lymphocytes | Cytometry | Phosphorylation | RESEARCH ARTICLE | B lymphocytes | Stem cells | Cell lines | Bone marrow | Bone marrow cells | Cells | Hematopoietic stem cells | STEM-CELLS | ACTIVATION | LYMPHOCYTE | MULTIDISCIPLINARY SCIENCES | MYELOGENOUS LEUKEMIA | TYROSINE KINASE INHIBITOR | FLOW-CYTOMETRY | DASATINIB | IDENTIFICATION | QUANTITATIVE-ANALYSIS | SIGNALING NETWORKS | Lanthanoid Series Elements | Leukocytes, Mononuclear - metabolism | Flow Cytometry - methods | Humans | Antibodies | Lymphocyte Subsets - immunology | Lymphocyte Subsets - metabolism | T-Lymphocytes - metabolism | Hematopoiesis | Single-Cell Analysis - methods | T-Lymphocytes - drug effects | Bone Marrow Cells - immunology | Leukocytes, Mononuclear - immunology | Mass Spectrometry | Bone Marrow Cells - drug effects | B-Lymphocytes - metabolism | Dasatinib | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Bone Marrow Cells - cytology | Lymphocyte Activation | Lymphocyte Subsets - drug effects | Immunophenotyping | Pyrimidines - pharmacology | Transition Elements | B-Lymphocytes - drug effects | Algorithms | B-Lymphocytes - immunology | Signal Transduction - drug effects | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Antigens, Surface - analysis | Bone Marrow Cells - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Evaluation | Flow cytometry | Immune response | Research | Immunopharmacology | Methods
Journal Article
Cell, ISSN 0092-8674, 2011, Volume 144, Issue 6, pp. 864 - 873
The flood of genome-wide data generated by high-throughput technologies currently provides biologists with an unprecedented opportunity: to manipulate, query,... 
ACTIVATION | MODULE | INHIBITION | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTIONAL NETWORK | DYNAMICS | REGULATORS | IDENTIFICATION | MAP | GENOME | CELL BIOLOGY | Models, Genetic | Animals | Mutation | Neoplasms - genetics | Humans | Care and treatment | Models | Analysis | Genomics | Cancer
Journal Article
Nature, ISSN 0028-0836, 01/2018, Volume 553, Issue 7689, pp. 467 - 472
Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome segregation during mitosis. Although chromosomal instability is... 
BREAST-CANCER | MIGRATION | CELLS | ANEUPLOIDY | ACTIVATION | EVOLUTION | PROGNOSIS | PATHWAY | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | EXPRESSION | Breast Neoplasms - secondary | DNA, Neoplasm - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Brain Neoplasms - pathology | NF-kappa B - metabolism | Cytosol - enzymology | Brain Neoplasms - secondary | Inflammation - metabolism | Female | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Cell Line | Micronuclei, Chromosome-Defective | Chromosome Segregation | Brain Neoplasms - genetics | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Chromosomal Instability - genetics | Neoplasm Metastasis - genetics | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Inflammation - genetics | Cytosol - metabolism | Head and Neck Neoplasms - genetics | Mesoderm - metabolism | Mice | Complications and side effects | Development and progression | Genetic aspects | Metastasis | Chromosomal instability syndromes | Genetic suppression | Mitosis | Activation | Genomes | Cytosol | Metastases | Genomic instability | Stimulators | Signal transduction | Cyclic GMP | Chromosomes | Deoxyribonucleic acid--DNA | NF-κB protein | Stability | AMP | Organs | Breast cancer | Survival analysis | Signaling | Medical prognosis | Micronuclei | Interferon | Cancer | Tumors
Journal Article
Nature Methods, ISSN 1548-7091, 09/2015, Volume 12, Issue 10, pp. 951 - 954
An accurate dissection of sources of cell-to-cell variability is crucial for quantitative biology at the single-cell level but has been challenging for the... 
MITOSIS | ACTIVATION | PATHWAY | KINASE | BIOCHEMICAL RESEARCH METHODS | EXPRESSION | ERK | Observations | Cellular control mechanisms | Cytology | Innovations | Cellular biology | Genetic markers | Cell cycle
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 06/2016, Volume 34, Issue 6, pp. 637 - 645
Journal Article
Nature Protocols, ISSN 1754-2189, 01/2015, Volume 10, Issue 2, pp. 316 - 333
Mass-tag cell barcoding (MCB) labels individual cell samples with unique combinatorial barcodes, after which they are pooled for processing and measurement as... 
BIOCHEMICAL RESEARCH METHODS | CYTOMETRY DATA | SAMPLES | Staining and Labeling - methods | Flow Cytometry - methods | Palladium | Software | Algorithms | Single-Cell Analysis - methods | Medical laboratory technology | Medical technology | Bar codes | Innovations | Properties | Contrast media
Journal Article
SCIENCE, ISSN 0036-8075, 11/2014, Volume 346, Issue 6213, pp. 1079 - 1079
Cellular circuits sense the environment, process signals, and compute decisions using networks of interacting proteins. To model such a system, the abundance... 
PATHWAYS | IMMUNE | RESPONSES | CD4 | ACTIVATION | MUTUAL INFORMATION | MASS CYTOMETRY | MULTIDISCIPLINARY SCIENCES | GENERATION | NAIVE | Proteins | Signal transduction | Flow cytometry | T cell receptors | Cellular biology | Networks | Cellular | Circuits | Information flow | Abundance | Mathematical models | Kinases
Journal Article