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Cell, ISSN 0092-8674, 06/2013, Volume 153, Issue 6, p. 1239
A "switch" from oxidative phosphorylation (OXPHOS) to aerobic glycolysis is a hallmark of T cell activation and is thought to be required to meet the metabolic... 
Journal Article
Science, ISSN 0036-8075, 04/2018, Volume 360, Issue 6387, pp. 377 - 378
Autoimmune and inflammatory diseases are diverse conditions caused by inappropriate and prolonged activation of immune cells with associated ongoing production... 
Multiple sclerosis | Immune response | Psoriasis | Medical services | Metabolism | Inflammatory diseases | Glucose metabolism | Fumaric acid | Demyelination | Glycolysis | Glyceraldehyde-3-phosphate dehydrogenase | Skin | Autoimmune diseases | Immune system
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2019, Volume 20, Issue 7, pp. 793 - 801
Unlike other cells in the body, immune cells have to be able to enter and adapt to life within diverse tissues. Immune cells develop within dedicated immune... 
CRUCIAL ROLE | ALTERNATIVELY ACTIVATED MACROPHAGES | ORCHESTRATE DEVELOPMENT | DENDRITIC CELL | FATTY-ACID | REGULATORY T-CELLS | PPAR-GAMMA | BROWN ADIPOSE-TISSUE | IMMUNOLOGY | DIET-INDUCED OBESITY | MAJOR ORGANS | Proteins | Health aspects | Genetic transcription | Cells | Research | Adaptations | Metabolic rate | Transcription | Organs | Bone marrow | Homeostasis | Lymphoid tissue | Tissues | Metabolism | Immune system | Thymus | Adaptation
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 2019, Volume 19, Issue 5, pp. 324 - 335
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 01/2015, Volume 15, Issue 1, pp. 18 - 29
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 01/2016, Volume 212, Issue 1, p. 2121
Journal Article
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 4, p. 1137
(Cell 165, 1708–1720; June 16, 2016) Our article investigated the effects of the metabolites produced by gut bacteria on intestinal stem cells and the role of... 
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 419 - 430
Macrophage polarization involves a coordinated metabolic and transcriptional rewiring that is only partially understood. By using an integrated high-throughput... 
IMMUNITY | CELLS | ACTIVATION | INFLAMMATION | NITRIC-OXIDE | INNATE | GLYCOSYLATION | IMMUNOLOGY | Glutamine - deficiency | Aspartic Acid - immunology | Argininosuccinic Acid - immunology | Mitochondria - immunology | Chemokine CCL22 - immunology | Metabolic Networks and Pathways - immunology | Mitochondria - genetics | Argininosuccinic Acid - metabolism | Gene Regulatory Networks - immunology | Isocitrate Dehydrogenase - immunology | Macrophages - immunology | Uridine Diphosphate N-Acetylglucosamine - metabolism | Nitric Oxide - immunology | Macrophages - classification | Aspartate Aminotransferase, Mitochondrial - immunology | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Isocitrate Dehydrogenase - genetics | Glycosylation | Mitochondria - metabolism | Macrophages - cytology | Immunity, Innate | Citric Acid Cycle | Uridine Diphosphate N-Acetylglucosamine - immunology | Chemokine CCL22 - genetics | Macrophages - metabolism | Metabolic Networks and Pathways - genetics | Animals | Interleukin-6 - immunology | Transcription, Genetic - immunology | Aspartic Acid - metabolism | Mice | Aspartate Aminotransferase, Mitochondrial - genetics | Nitric Oxide - metabolism | Enzymes | Tracers (Biology) | Analysis | Nitric oxide | Physiological aspects | Aspartate | Genetic aspects | Genetic transcription | Macrophages | Glutamine | Metabolites | Rodents | Scientific imaging | Metabolism | Labeling | Mass spectrometry
Journal Article
Immunity, ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 75 - 88
Generation of CD8 memory T cells requires metabolic reprogramming that is characterized by enhanced mitochondrial fatty-acid oxidation (FAO). However, where... 
OXIDATION | LIFE-SPAN | ACTIVATION | CATABOLISM | LIPID-METABOLISM | BIOGENESIS | FATTY-ACID-METABOLISM | PROLIFERATION | IMMUNOLOGY | PROTEINS | ADIPOSE-TISSUE | Lipids | Glucose | Metabolism | Lymphocytes | Experiments
Journal Article