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Nature Reviews Cancer, ISSN 1474-175X, 02/2015, Volume 15, Issue 3, pp. 166 - 180
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2019, Volume 73, Issue 2, pp. 212 - 223.e7
Cohesin subunits are frequently mutated in cancer, but how they function as tumor suppressors is unknown. Cohesin mediates sister chromatid cohesion, but this... 
PBAF | PBRM1 | STAG2 | SA2 | SWI/SNF | cancer | transcriptional silencing | DNA repair | SMARCA4 | INACTIVATION | MUTATIONAL PROCESSES | REPAIR | PROTEIN | REPLICATION | CHROMATIN | ROLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | HOMOLOGOUS RECOMBINATION | CANCER | CELL BIOLOGY | SWI | SNF
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 13, pp. 21290 - 21304
Background: The key to interpreting the contribution of a disease-associated mutation in the development and progression of cancer is an understanding of the... 
Tumour suppressor | Mutation | Oncogene | Cancer | PROTEIN | VARIANTS | tumour suppressor | STABILITY | oncogene | SOMATIC MUTATIONS | CELL BIOLOGY | mutation | PATHOGENICITY | DATABASE | FUNCTIONAL IMPACT | SEQUENCE | GENES | cancer | Oncogenes - genetics | Computational Biology - methods | Neoplasms - genetics | Humans | Models, Molecular | DNA Mutational Analysis - methods | Mutation - genetics | Genes, Tumor Suppressor
Journal Article
Expert Opinion on Drug Discovery, ISSN 1746-0441, 06/2017, Volume 12, Issue 6, pp. 599 - 609
Journal Article
BIOSCIENCE REPORTS, ISSN 0144-8463, 08/2017, Volume 37
Bioinformatics approaches are becoming ever more essential in translational drug discovery both in academia and within the pharmaceutical industry.... 
TYROSINE KINASE INHIBITORS | CELL LUNG-CANCER | THERAPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | BIOLOGY | TARGETS | MUTATIONS | BINDING-SITES | STRATIFICATION | GENOME-WIDE ASSOCIATION | CELL BIOLOGY
Journal Article
Bioscience Reports, ISSN 0144-8463, 08/2017, Volume 37, Issue 4, p. BSR20160180
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2003, Volume 31, Issue 1, pp. 452 - 455
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 10/1999, Volume 293, Issue 2, pp. 333 - 342
The evolution of proteins and their functions is reviewed from a structural perspective in the light of the current database. Protein domain families segregate... 
protein folds | protein evolution | SEQUENCES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALGORITHM | enzymes | CLASSIFICATION | protein function | protein structure | DATABASE | FAMILIES | ASSIGNMENT | GENERATION | STRUCTURAL DOMAINS
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 1/2009, Volume 37, Issue suppl_1, pp. D824 - D831
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 01/2000, Volume 28, Issue 1, pp. 277 - 282
We report the latest release (version 1.6) of the CATH protein:domains database (http://www.biochem.ucl. ac.uk/bsm/cath), This is a hierarchical classification... 
ASSIGNMENT | PROTEIN STRUCTURES | DATABASE | SEARCH | BIOCHEMISTRY & MOLECULAR BIOLOGY
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/1999, Volume 27, Issue 1, pp. 275 - 279
Journal Article