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Scientific Reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, pp. 90 - 12
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7510, pp. 478 - 482
Cutaneous melanoma is epidemiologically linked to ultraviolet radiation (UVR), but the molecular mechanisms by which UVR drives melanomagenesis remain... 
P53 GAIN | MULTIDISCIPLINARY SCIENCES | PREVENTION | MICE | SUNSCREEN | MUTATIONS | MELANOCYTIC NEVI | SEQUENCING DATA | CANCER | EXPRESSION | EXPOSURE | Cell Transformation, Neoplastic - radiation effects | Melanoma - etiology | Humans | Melanocytes - metabolism | Sunburn - genetics | Tumor Suppressor Protein p53 - genetics | Melanocytes - radiation effects | Nevus - genetics | Mutagenesis - radiation effects | Cell Transformation, Neoplastic - genetics | Melanoma - genetics | Base Sequence | Melanocytes - pathology | Sunburn - complications | DNA Damage - genetics | Female | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Nevus - etiology | Melanoma - metabolism | Skin Neoplasms - pathology | Mutation - radiation effects | Mice, Inbred C57BL | Mutagenesis - genetics | Tumor Suppressor Protein p53 - metabolism | Melanoma - pathology | Mutation - genetics | Ultraviolet Rays - adverse effects | Skin Neoplasms - metabolism | Animals | Nevus - pathology | Proto-Oncogene Proteins B-raf - genetics | Skin Neoplasms - genetics | Mice | Skin Neoplasms - etiology | Sunburn - etiology | Sunscreening Agents - pharmacology | Nevus - metabolism | Ultraviolet radiation | Rodents | Analysis | Melanoma | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Sunscreen | Mutation | Deoxyribonucleic acid--DNA | Tumors | Skin cancer
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 11/2014, Volume 27, Issue 6, pp. 1162 - 1166
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 01/2017, Volume 16, Issue 1, pp. 25 - 34
AZD6738 is an orally active ATR inhibitor (ATRi) currently in phase I clinical trials. We found in vitro growth inhibitory activity of this ATRi in a panel of... 
CANCER-CELLS | ONCOLOGY | CONSEQUENCES | SENSITIVITY | TUMOR-CELLS | CHECKPOINT | IDENTIFICATION | CHROMOTHRIPSIS | STRESS | DEPENDENT MANNER | RADIATION | Homologous Recombination - drug effects | Tumor Burden - radiation effects | Humans | Tumor Suppressor Protein p53 - genetics | G2 Phase Cell Cycle Checkpoints - radiation effects | G2 Phase Cell Cycle Checkpoints - drug effects | Micronuclei, Chromosome-Defective - drug effects | Inhibitory Concentration 50 | Micronuclei, Chromosome-Defective - radiation effects | Disease Models, Animal | Radiation, Ionizing | DNA Damage - drug effects | Sulfoxides - pharmacology | Homologous Recombination - radiation effects | Radiation-Sensitizing Agents - pharmacology | Tumor Suppressor Protein p53 - metabolism | Pyrimidines - pharmacology | Radiation Tolerance - drug effects | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | DNA Damage - radiation effects | Biotechnology | Mitosis | p53 Protein | DNA damage | Homologous recombination | Cytology | Radiation | Clinical trials | Fluorescence | Homology | Nuclei | Ubiquitination | Radiosensitization | Inhibition | Deoxyribonucleic acid--DNA | BRCA2 protein | Medical research | Radiation effects | CHK1 protein | Breast cancer | Tumor cell lines | Inhibitors | Micronuclei | Cell lines | Nuclei (cytology) | Three dimensional models | Radiation damage | Cancer
Journal Article
SAE International Journal of Fuels and Lubricants, ISSN 1946-3952, 09/2015, Volume 8, Issue 3
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 12/2014, Volume 12, Issue 12 Supplement, pp. B11 - B11
Journal Article
International journal of epidemiology, ISSN 0300-5771, 03/2019
Despite advances in life expectancy, low socioeconomic status is associated with a shorter lifespan. This study was conducted to investigate socioeconomic... 
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 11/2014, Volume 307, Issue 9, pp. E822 - E829
Plasma glucose, insulin, and C-peptide responses during an OGTT are informative for both research and clinical practice in type 2 diabetes. The aim of this... 
Oral glucose tolerance | Type 2 diabetes | Obesity | β-cell dysfunction | Insulin sensitivity | Hyperinsulinemic euglycemic clamp | Insulin sensitivity index | Insulin resistance | β-cell function | Disposition index | Insulin secretion | PHYSIOLOGY | CLAMP | insulin secretion | beta-cell dysfunction | EXERCISE | insulin sensitivity | beta-cell function | type 2 diabetes | TYPE-2 DIABETIC-PATIENTS | METABOLISM | ENDOCRINOLOGY & METABOLISM | disposition index | RESISTANCE | oral glucose tolerance | SECRETION | insulin resistance | insulin sensitivity index | obesity | hyperinsulinemic euglycemic clamp | Glucose Intolerance - metabolism | Glycated Hemoglobin A - analysis | Prediabetic State - metabolism | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Glucose Intolerance - blood | Glucose Intolerance - diagnosis | Insulin-Secreting Cells - metabolism | Female | Insulin Secretion | Glucose Intolerance - physiopathology | Diagnosis, Differential | Glucose Tolerance Test | Prediabetic State - blood | Blood Glucose - analysis | Insulin Resistance | Disease Progression | Allostasis | Prediabetic State - diagnosis | Diabetes Mellitus, Type 2 - diagnosis | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Prediabetic State - physiopathology | Denmark | Ohio | Glucose Clamp Technique | Cohort Studies
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 01/2017, Volume 17, Issue 1, p. 86
Background: Concurrent cisplatin radiotherapy (CCRT) is a current standard-of-care for locally advanced head and neck squamous cell carcinoma (HNSCC). However,... 
FANCA | ATM | DDR | RAD51 | AUY922 | HNSCC | TUMOR-CELLS | RADIATION SENSITIVITY | FANCONI-ANEMIA | LUNG-CANCER | REPAIR | RADIOSENSITIZATION | ONCOLOGY | GELDANAMYCIN | SQUAMOUS-CELL CARCINOMA | MULTITARGET APPROACH | Homologous Recombination - drug effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | DNA Repair - radiation effects | DNA Repair - genetics | Carcinoma, Squamous Cell - radiotherapy | Head and Neck Neoplasms - metabolism | Organoplatinum Compounds - pharmacology | Tumor Suppressor Protein p53 - genetics | Resorcinols - pharmacology | Chromosomes - drug effects | Squamous Cell Carcinoma of Head and Neck | Chromosomes - genetics | DNA Damage - genetics | Female | DNA Fragmentation - drug effects | DNA Damage - drug effects | Chemoradiotherapy - methods | DNA Repair - drug effects | Head and Neck Neoplasms - drug therapy | Isoxazoles - pharmacology | BRCA1 Protein - genetics | Head and Neck Neoplasms - radiotherapy | Animals | Carcinoma, Squamous Cell - drug therapy | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Mice, Nude | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | DNA Damage - radiation effects | Care and treatment | Usage | DNA damage | Head and neck cancer | Dosage and administration | Research | Radiotherapy | Cisplatin
Journal Article
Immuno-analyse et biologie spécialisée, ISSN 0923-2532, 2006, Volume 21, Issue 4, pp. 234 - 238
The presence of TSH-receptor antibodies (TRAb) in serum is a key abnormality in Graves' disease (GD). The latest generation of assays detects TRAb in around... 
Multinodular toxic goitre | Assay | Analyse | Maladie de Graves | Graves' disease | Autoanticorps du récepteur de la TSH | Goitre malin multinodulaire | TSH receptor antibodies | Hypothyroidism | Hypothyroïdisme | Measurement | Viral antibodies | Antibodies | Thyroid hormones | Pregnant women
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2017, Volume 141, Issue 4, pp. 687 - 693
Journal Article
Cancer Discovery, ISSN 2159-8274, 2013, Volume 3, Issue 2, pp. 158 - 167
Journal Article
Journal Article