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Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 5627 - 5627
Journal Article
EMBO Journal, ISSN 0261-4189, 09/2011, Volume 30, Issue 18, p. 3663
  The mRNA 3[variant prime]UTR has an important role in post-transcriptional regulation. An article in this issue of The EMBO Journal describes a new role for... 
Ribonucleic acid--RNA | Molecular biology | Kinases
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 12/2011, Volume 24, Issue 6, pp. 1107 - 1111
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 498, Issue 7452, pp. 109 - 112
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 1266 - 1266
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 41, pp. 43146 - 43161
Fra-1 (Fos-related antigen-1) is a member of the AP-1 (activator protein-1) family of transcription factors. We previously showed that Fra-1 is necessary for... 
In vivo | Colon cancer | Metastasis | Wnt | Fra-1 | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7372, pp. 186 - 187
For this, they used an ingenious transgenic strategy9 in which specific cell groups could be killed by a drug-inducible caspase enzyme. [...] the authors... 
Proteins | Enzymes | Rodents
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 08/2017, Volume 9, Issue 8, pp. 987 - 989
Considerable clinical successes have been achieved in cancer treatment since the introduction of targeted therapies. However, almost inevitably tumors develop... 
MEDICINE, RESEARCH & EXPERIMENTAL | METASTATIC MELANOMA | BRAF | THERAPY | Paracrine signalling | Drug tolerance | Tumors | Cancer | Index Medicus | Skin | Views
Journal Article
The EMBO Journal, ISSN 0261-4189, 09/2011, Volume 30, Issue 18, pp. 3663 - 3664
EMBO J 30 18, 3714-3728 (2011); published online 29 July 2011A/U-rich elements (AREs) are short sequences in the 3′UTRs of genes, acting in cis to regulate... 
ELEMENTS | ONCOGENE-INDUCED SENESCENCE | CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN-BETA | CELL BIOLOGY | Aging | 3' Untranslated Regions | Humans | CCAAT-Enhancer-Binding Protein-beta - metabolism | Oncogene Protein p21(ras) - metabolism | Gene Expression Regulation | Index Medicus | Have You Seen...?
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5712 - 5712
Increased expression of the Microphthalmia-associated transcription factor (MITF) contributes to melanoma progression and resistance to BRAF pathway... 
BRAF INHIBITION | TYROSINE KINASE AXL | RAF INHIBITION | CELLS | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | IMPROVED SURVIVAL | MEK INHIBITORS | UP-REGULATION | CONFERS RESISTANCE | Prognosis | Skin Neoplasms - drug therapy | Humans | Gene Expression Regulation, Neoplastic | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Melanoma - genetics | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Indoles - pharmacology | Pyrimidinones - pharmacology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | Skin Neoplasms - pathology | Proto-Oncogene Proteins - antagonists & inhibitors | Microphthalmia-Associated Transcription Factor - metabolism | Signal Transduction | Proto-Oncogene Proteins - genetics | Imidazoles - pharmacology | Melanoma - pathology | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Skin Neoplasms - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Proto-Oncogene Proteins B-raf - genetics | Aminopyridines - pharmacology | Melanoma - drug therapy | Skin Neoplasms - genetics | Cell Line, Tumor | Oximes - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Microphthalmia-Associated Transcription Factor - genetics | Pyridones - pharmacology | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2005, Volume 436, Issue 7051, pp. 720 - 724
Most normal mammalian cells have a finite lifespan(1), thought to constitute a protective mechanism against unlimited proliferation(2-4). This phenomenon,... 
TRANSFORMATION | ONCOGENE | P16 | TUMOR SUPPRESSION | BRAF MUTATIONS | MULTIDISCIPLINARY SCIENCES | GENES | MALIGNANT-MELANOMA | CANCER | P53
Journal Article