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eLife, ISSN 2050-084X, 09/2019, Volume 8
Cells rely on prolyl hydroxylase enzymes to sense low levels of oxygen, but they might act on fewer targets than previously thought. 
Proteins | Enzymes | Researchers | Hydroxylase | Hypoxia | Amino acids | Physiology | Prolyl hydroxylase | Experiments
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 06/2002, Volume 16, Issue 12, pp. 1466 - 1471
Journal Article
MethodsX, ISSN 2215-0161, 2018, Volume 5, pp. 257 - 267
Chemogenetics uses engineered proteins that are controlled by small molecule actuators, allowing in vivo functional studies of proteins with temporal and dose... 
G-protein-coupled receptor (GPCR) | Chemical synthesis | Chemical-genetics | Preparation and application of clozapine N-oxide (CNO)
Journal Article
by Yusuf, Dimas and Butland, Stefanie L and Swanson, Magdalena I and Bolotin, Eugene and Ticoll, Amy and Cheung, Warren A and Zhang, Xiao Yu Cindy and Dickman, Christopher T. D and Fulton, Debra L and Lim, Jonathan S and Schnabl, Jake M and Ramos, Oscar H. P and Vasseur-Cognet, Mireille and de Leeuw, Charles N and Simpson, Elizabeth M and Ryffel, Gerhart U and Lam, Eric W.-F and Kist, Ralf and Wilson, Miranda S. C and Marco-Ferreres, Raquel and Brosens, Jan J and Beccari, Leonardo L and Bovolenta, Paola and Benayoun, Bérénice A and Monteiro, Lara J and Schwenen, Helma D. C and Grontved, Lars and Wederell, Elizabeth and Manup, Susanne and Veitia, Reiner A and Chakravarthy, Harini and Hoodless, Pamela A and Mancarelli, M. Michela and Torbett, Bruce E and Banham, Alison H and Reddy, Sekhar P and Cullum, Rebecca L and Liedtke, Michaela and Tschan, Mario P and Vaz, Michelle and Rizzino, Angie and Zannini, Mariastella and Frietze, Seth and Farnham, Peggy J and Eijkelenboom, Astrid and Brown, Philip J and Laperrière, David and Leprince, Dominique and de Cristofaro, Tiziana and Prince, Kelly L and Putker, Marrit and del Peso, Luis and Camenisch, Gieri and Wenger, Roland H and Mikula, Michal and Rozendaal, Marieke and Mader, Sylvie and Ostrowski, Jerzy and Rhodes, Simon J and van Rechem, Capucine and Boulay, Gaylor and Olechnowicz, Sam W. Z and Breslin, Mary B and Lan, Michael S and Nanan, Kyster K and Wegner, Michael and Hou, Juan and Mullen, Rachel D and Colvin, Stephanie C and Noy, Peter John and Webb, Carol F and Witek, Matthew E and Ferrell, Scott and Daniel, Juliet M and Park, Jason and Waldman, Scott A and Peet, Daniel J and Taggart, Michael and Jayaraman, Padma-Sheela and Karrich, Julien J and Blom, Bianca and Vesuna, Farhad and O'Geen, Henriette and Sun, Yunfu and Gronostajski, Richard M and Woodcroft, Mark W and Hough, Margaret R and Chen, Edwin and Europe-Finner, G. Nicholas and Karolczak-Bayatti, Magdalena and Bailey, Jarrod and Hankinson, Oliver and Raman, Venu and Lebrun, David P and Biswal, Shyam and Harvey, Christopher J and Debruyne, Jason P and Hogenesch, John B and Hevner, Robert F and Héligon, Christophe and ...
Genome biology, ISSN 1465-6906, 2012, Volume 13, Issue 3, pp. R24 - R24
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2008, Volume 105, Issue 9, pp. 3368 - 3373
Journal Article
by Sullivan, Patrick and Yuan, Maoli and Coleman, John and Destefano, Joanne and Zhang, Xinsheng and Yates, Nicole and Barouch, Dan and Ackerman, Margaret and Decamp, Allan and Alter, Galit and Tomaras, Georgia and Tomaras, Georgia and Montefiori, David and Montefiori, David and Rasmussen, Beth and Morrow, Gavin and Koff, Wayne and Kashuba, Angela and Kashuba, Angela and Mascola, John and Picker, Louis and Kent, Stephen and Selhorst, Philippe and Masson, Lindi and Ngandu, Nobubelo and Rademeyer, Cecilia and Karim, Quarraisha Abdool and Kijak, Gustavo and Barouch, Dan and Rasheed, Ata Ur and Havenar-Daughton, Colin and Pham, Matthew and Kovalenkov, Yevgeniy and Gumber, Sanjeev and Johnson, Matthew and Wrammert, Jens and Villinger, Francois and Haynes, Barton and Haynes, Barton and Fox, Christopher and Reed, Steve and Vasilakos, John and Tomai, Mark and Crotty, Shane and Ahmed, Rafi and Pulendran, Bali and Fukazawa, Yoshinori and Lifson, Jeffrey and Lifson, Jeffrey and Moore, Penny and Chatora, Kumbirai and Skorochod, Elisabeth and Madidi, Ngonidzashe and Gomez, Anabel and Ncube, Getrude and Sundaram, Maaya and Kretschmer, Steve and Pauthner, Matthias and Briney, Bryan and Lee, Jeong Hyun and Saye-Francisco, Karen and Hsueh, Jessica and Ramos, Alejandra and Le, Khoa and Jones, Meaghan and Jardine, Joseph and Bastidas, Raiza and Sarkar, Anita and Liang, Chi-Hui and Wilson, Ian and Ward, Andrew and Zhu, Jiang and Poignard, Pascal and Burton, Dennis and Krebs, Shelly and Law, Wiliam and Gift, Syna and Chenine, Agnes and Rolland, Morgane and Moody, M. Anthony and Jarosinski, Marissa and Georgiev, Ivelin and Chuang, Gwo-Yu and Chuang, Gwo-Yu and Asokan, Mangaiarkarasi and Bailer, Robert T and Cale, Evan M and Louder, Mark and Kwong, Peter D and Polonis, Victoria and Tovanabutra, Sodsai and Robb, Merlin and Mascola, John R and Wibmer, Constantinos Kurt and Wibmer, Constantinos Kurt and Madzorera, Vimbai S and Doria-Rose, Nicole A and Morris, Lynn and Moore, Penny L and Anthony, Colin and ...
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2016, Volume 32, Issue S1, pp. 1 - 409
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Journal of Clinical Investigation, ISSN 0021-9738, 07/2013, Volume 123, Issue 7, pp. 3037 - 3041
Journal Article
Cell Metabolism, ISSN 1550-4131, 2010, Volume 11, Issue 5, pp. 364 - 378
Factor inhibiting HIF-1α (FIH) is an asparaginyl hydroxylase. Hydroxylation of HIF-α proteins by FIH blocks association of HIFs with the transcriptional... 
HUMDISEASE | SIGNALING | VENTILATORY RESPONSES | OXYGEN | HIF-1 | TRANSCRIPTIONAL ACTIVITY | FACTOR FIH | HYPOXIA-INDUCIBLE-FACTOR | IN-VIVO | ENDOCRINOLOGY & METABOLISM | MICE | CAROTID-BODY | ANKYRIN REPEAT DOMAIN | CELL BIOLOGY
Journal Article