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1. Full Text TH-302 in Combination with Radiotherapy Enhances the Therapeutic Outcome and Is Associated with Pretreatment [F-18]HX4 Hypoxia PET Imaging
by Peeters, Sarah G. J. A and Zegers, Catharina M. L and Biemans, Rianne and Lieuwes, Natasja G and van Stiphout, Ruud G. P. M and Yaromina, Ala and Sun, Jessica D and Hart, Charles P and Windhorst, Albert D and van Elmpt, Wouter and Dubois, Ludwig J and Lambin, Philippe
Clinical cancer research, ISSN 1078-0432, 07/2015, Volume 21, Issue 13, pp. 2984 - 2992
Life Sciences & Biomedicine | Oncology | Science & Technology | Nitroimidazoles - pharmacology | Phosphoramide Mustards - pharmacology | Rats | Treatment Outcome | Antineoplastic Agents - therapeutic use | Lung Neoplasms - therapy | Positron-Emission Tomography | Chemoradiotherapy | Cell Hypoxia | Xenograft Model Antitumor Assays | Carcinoma, Non-Small-Cell Lung - therapy | Animals | Imidazoles | Nitroimidazoles - therapeutic use | Phosphoramide Mustards - therapeutic use | Triazoles | Lung Neoplasms - diagnostic imaging | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Radiopharmaceuticals | Index Medicus
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2. Full Text Preclinical Assessment of Efficacy of Radiation Dose Painting Based on Intratumoral FDG-PET Uptake
by Trani, Daniela and Yaromina, Ala and Dubois, Ludwig and Granzier, Marlies and Peeters, Sarah G. J. A and Biemans, Rianne and Nalbantov, Georgi and Lieuwes, Natasja and Reniers, Brigitte and Troost, Esther E. G. C and Verhaegen, Frank and Lambin, Philippe
Clinical cancer research, ISSN 1078-0432, 12/2015, Volume 21, Issue 24, pp. 5511 - 5518
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Rhabdomyosarcoma - diagnosis | Tumor Burden - radiation effects | Humans | Fluorodeoxyglucose F18 - metabolism | Rats | Male | Neoplasms - diagnosis | Positron-Emission Tomography | Radiation Dosage | Rhabdomyosarcoma - radiotherapy | Animals | Neoplasms - radiotherapy | Dose-Response Relationship, Radiation | Disease Models, Animal | Index Medicus
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3. Full Text Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs
by Dubois, Ludwig and Peeters, Sarah G.J.A and van Kuijk, Simon J.A and Yaromina, Ala and Lieuwes, Natasja G and Saraya, Ruchi and Biemans, Rianne and Rami, Marouan and Parvathaneni, Nanda Kumar and Vullo, Daniela and Vooijs, Marc and Supuran, Claudiu T and Winum, Jean-Yves and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2013, Volume 108, Issue 3, pp. 523 - 528
Hematology, Oncology and Palliative Medicine | Sulfamide | Carbonic anhydrase IX (CAIX) | 5-Nitroimidazole | Radiotherapy | Dual targeting | Carbonic Anhydrases - physiology | Animals | Nitroimidazoles - pharmacology | Antigens, Neoplasm - physiology | Humans | Radiation-Sensitizing Agents - pharmacology | Colorectal Neoplasms - radiotherapy | Cell Line, Tumor | Mice | Carbonic Anhydrase Inhibitors - pharmacology | Carbonic Anhydrase IX | Health aspects | Tumors | Index Medicus
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4. Full Text [F-18]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models
by Peeters, Sarah G. J. A and Dubois, Ludwig and Lieuwes, Natasja G and Laan, Dennis and Mooijer, Martien and Schuit, Robert C and Vullo, Daniela and Supuran, Claudiu T and Eriksson, Jonas and Windhorst, Albert D and Lambin, Philippe
Molecular imaging and biology, ISSN 1536-1632, 10/2015, Volume 17, Issue 5, pp. 615 - 619
CAIX | Preclinical | PET imaging | [F-18]VM4-037 | Biodistribution | Medicine & Public Health | [ 18 F]VM4-037 | Imaging / Radiology | F]VM4-037 | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Neoplasms - metabolism | Sulfonamides - chemistry | Dipeptides - pharmacokinetics | Humans | Molecular Imaging - methods | Positron-Emission Tomography - methods | Dipeptides - chemistry | Sulfonamides - pharmacokinetics | Carbonic Anhydrases - metabolism | Tissue Distribution | Antigens, Neoplasm - metabolism | Cell Line, Tumor | Neoplasms - pathology | Carbonic Anhydrase IX | Tracers (Biology) | Developmental biology | Liver | Tumors | Index Medicus | [18F]VM4-037 | Brief
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5. Full Text New ways to image and target tumour hypoxia and its molecular responses
by Dubois, Ludwig J and Niemans, Raymon and van Kuijk, Simon J.A and Panth, Kranthi M and Parvathaneni, Nanda-Kumar and Peeters, Sarah G.J.A and Zegers, Catharina M.L and Rekers, Nicolle H and van Gisbergen, Marike W and Biemans, Rianne and Lieuwes, Natasja G and Spiegelberg, Linda and Yaromina, Ala and Winum, Jean-Yves and Vooijs, Marc and Lambin, Philippe
Radiotherapy and oncology, ISSN 0167-8140, 2015, Volume 116, Issue 3, pp. 352 - 357
Hematology, Oncology and Palliative Medicine | Therapy | Hypoxia | Carbonic anhydrase IX | Window-of-opportunity trial | Imaging | Hypoxia - physiopathology | Positron-Emission Tomography | Neoplasms - physiopathology | Hypoxia - diagnostic imaging | Neoplasms - diagnostic imaging | Humans | Tumors | Index Medicus
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6. Full Text Two-Dimensional Covalent Crystals by Chemical Conversion of Thin van der Waals Materials
by Sreepal, Vishnu and Yagmurcukardes, Mehmet and Vasu, Kalangi S and Kelly, Daniel J and Taylor, Sarah F. R and Kravets, Vasyl G and Kudrynskyi, Zakhar and Kovalyuk, Zakhar D and Patanè, Amalia and Grigorenko, Alexander N and Haigh, Sarah J and Hardacre, Christopher and Eaves, Laurence and Sahin, Hasan and Geim, Andre K and Peeters, Francois M and Nair, Rahul R
Nano letters, ISSN 1530-6984, 09/2019, Volume 19, Issue 9, pp. 6475 - 6481
2D covalent crystal | fluorination | van der Waals materials | Indium selenide | indium fluoride | Materials Science | Materials Science, Multidisciplinary | Physics, Condensed Matter | Science & Technology - Other Topics | Chemistry, Physical | Physics | Science & Technology | Physics, Applied | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Technology | Chemistry, Multidisciplinary | Index Medicus | Physics - Materials Science | Letter
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7. Full Text A phase 1 'window-of-opportunity' trial testing evofosfamide (TH-302), a tumour-selective hypoxia-activated cytotoxic prodrug, with preoperative chemoradiotherapy in oesophageal adenocarcinoma patients
by Larue, Ruben T. H. M and Van de Voorde, Lien and Berbee, Maaike and van Elmpt, Wouter J. C and Dubois, Ludwig J and Panth, Kranthi M and Peeters, Sarah G. J. A and Claessens, Ann and Schreurs, Wendy M. J and Nap, Marius and Warmerdam, Fabienne A. R. M and Erdkamp, Frans L. G and Sosef, Meindert N and Lambin, Philippe
BMC cancer, ISSN 1471-2407, 08/2016, Volume 16, Issue 1, pp. 644 - 644
Oesophageal cancer | Hypoxia imaging | Dose limiting toxicity | Evofosfamide | Oesophagectomy | Window-of-opportunity trial | Neoadjuvant chemoradiotherapy | Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Hypoxia - drug effects | Nitroimidazoles - pharmacology | Phosphoramide Mustards - pharmacology | Humans | Esophagectomy | Male | Treatment Outcome | Positron-Emission Tomography - methods | Preoperative Care | Chemoradiotherapy, Adjuvant - methods | Dose-Response Relationship, Drug | Adenocarcinoma - therapy | Phosphoramide Mustards - administration & dosage | Survival Analysis | Female | Adenocarcinoma - diagnostic imaging | Esophageal Neoplasms - therapy | Esophageal Neoplasms - diagnostic imaging | Nitroimidazoles - administration & dosage | Adenocarcinoma | Chemotherapy | Research | Drug therapy | Esophageal cancer | Cancer | Index Medicus | Study Protocol
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8. Full Text Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression
by Gheuens, Sarah and Pierone, Gerald and Peeters, Patrick and Koralnik, Igor J
Journal of neurology, neurosurgery and psychiatry, ISSN 0022-3050, 03/2010, Volume 81, Issue 3, pp. 247 - 254
Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Surgery | Science & Technology | Neurology | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Leukoencephalopathy, Progressive Multifocal - immunology | HIV Seronegativity | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Male | Survival Rate | Leukoencephalopathy, Progressive Multifocal - diagnosis | Leukoencephalopathy, Progressive Multifocal - mortality | Opportunistic Infections - diagnosis | CD4-Positive T-Lymphocytes - immunology | Pregnancy | Magnetic Resonance Imaging | Neurologic Examination | Immune Tolerance - immunology | Brain - pathology | Adult | Female | Lymphopenia - immunology | Opportunistic Infections - immunology | Lymphopenia - diagnosis | Immunosuppression | Leukoencephalopathy, Progressive multifocal | Causes of | Polyoma virus | Research | Identification and classification | Risk factors | Index Medicus | idiopathic CD4+ T cell lymphocytopenia | immunosuppression | immunocompetent | progressive multifocal leukoencephalopathy | JC virus
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9. Full Text Confirmation of the role of pathogenic SMAD6 variants in bicuspid aortic valve-related aortopathy
by Luyckx, I and MacCarrick, G and Kempers, M.J.E and Meester, J. de and Geryl, C and Rombouts, O and Peeters, N and Claes, C and Boeckx, N and Sakalihasan, N and Jacquinet, A and Hoischen, A and Vandeweyer, G and Lent, S. Van and Saenen, J and Craenenbroeck, E. Van and Timmermans, J and Duijnhouwer, A.L and Dietz, H and Laer, L. Van and Loeys, B.L and Verstraeten, A
European journal of human genetics : EJHG, ISSN 1018-4813, 2019, Volume 27, Issue 7, pp. 1044 - 1053
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Bone Morphogenetic Protein 2 - genetics | Aneurysm, Dissecting - genetics | Aortic Aneurysm, Thoracic - genetics | Aortic Valve - abnormalities | Craniosynostoses - genetics | Humans | Middle Aged | Male | Bicuspid Aortic Valve Disease | Genetic Variation | Heart Valve Diseases - genetics | Adult | Female | Aged | Smad6 Protein - genetics | Bone morphogenetic protein 2 | Craniosynostosis | Coronary vessels | Alleles | Aneurysms | Aorta | Single-nucleotide polymorphism | Thorax | Aortic valve | Index Medicus | Congenital heart defects | Genetics research
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10. Full Text Atomically thin micas as proton-conducting membranes
by Mogg, L and Hao, G. -P and Zhang, S and Bacaksiz, C and Zou, Y. -C and Haigh, S. J and Peeters, F. M and Geim, A. K and Lozada-Hidalgo, M
Nature nanotechnology, ISSN 1748-3387, 10/2019, Volume 14, Issue 10, pp. 962 - 966
Science & Technology - Other Topics | Materials Science | Nanoscience & Nanotechnology | Technology | Materials Science, Multidisciplinary | Science & Technology | Protons | Conduction | Membranes | Crystals | Conductivity | Boron nitride | Cation exchanging | Conductors | Channels | Ion exchanging | Boron | Molybdenum disulfide | Graphene | Monolayers | Cations | Two dimensional materials | Hydroxyl groups | Crystal structure | Index Medicus
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11. Full Text A Comparative Study of the Hypoxia PET Tracers [18 F]HX4, [18 F]FAZA, and [18 F]FMISO in a Preclinical Tumor Model
by Peeters, Sarah G.J.A., MSc and Zegers, Catharina M.L., MSc and Lieuwes, Natasja G., BSc and van Elmpt, Wouter, PhD and Eriksson, Jonas, PhD and van Dongen, Guus A.M.S., PhD and Dubois, Ludwig, PhD and Lambin, Philippe, MD, PhD
International journal of radiation oncology, biology, physics, ISSN 0360-3016, 02/2015, Volume 91, Issue 2, pp. 351 - 359
Radiology | Hematology, Oncology and Palliative Medicine | Oncology | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Rhabdomyosarcoma - metabolism | Rats | Rhabdomyosarcoma - pathology | Misonidazole - pharmacokinetics | Imidazoles - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Rhabdomyosarcoma - diagnostic imaging | Oxygen - metabolism | Cell Hypoxia | Animals | Models, Biological | Computer Simulation | Sensitivity and Specificity | Cell Line, Tumor | Triazoles - pharmacokinetics | Nitroimidazoles - pharmacokinetics | PET imaging | Tracers (Biology) | Comparative analysis | Developmental biology | Tumors | Index Medicus | NEOPLASMS | BIOMEDICAL RADIOGRAPHY | NICOTINAMIDE | SENSITIVITY | CORRELATIONS | COMPARATIVE EVALUATIONS | CAT SCANNING | OXYGEN | MODIFICATIONS | ANOXIA | INJECTION | POSITRON COMPUTED TOMOGRAPHY | RESPIRATION | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | FLUORINE 18 | BLOOD
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12. A standard set of value-based patient-centered outcomes for breast cancer: The International Consortium for Health Outcomes Measurement (ICHOM) initiative
by Ong, Wee Loon and Schouwenburg, Maartje G and Van Bommel, Annelotte C.M and Stowell, Caleb and Allison, Kim H and Benn, Karen E and Browne, John P and Cooter, Rodney D and Delaney, Geoff P and Duhoux, Francois P and Ganz, Patricia A and Hancock, Patricia and Jagsi, Reshma and Knaul, Felicia M and Knip, Anne M and Koppert, Linetta B and Kuerer, Henry M and McLaughin, Sarah and Mureau, Marc A. M and Partridge, Ann H and Reid, Dereesa Purtell and Sheeran, Lisa and Smith, Thomas J and Stoutjesdijk, Mark J and Vrancken Peeters, Marie Jeanne T.F.D and Wengström, Yvonne and Yip, Cheng-Har and Saunders, Christobel
JAMA oncology, ISSN 2374-2437, 2017, Volume 3, Issue 5, pp. 677 - 685
Life Sciences & Biomedicine | Oncology | Science & Technology | Breast Neoplasms - therapy | Delphi Technique | Humans | Focus Groups | Quality of Life | Female | International Cooperation | Quality of Health Care | Patient Reported Outcome Measures
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