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1. Full Text Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
by Schwartzentruber, Jeremy and Korshunov, Andrey and Liu, Xiao-Yang and Jones, David T. W and Pfaff, Elke and Jacob, Karine and Sturm, Dominik and Fontebasso, Adam M and Quang, Dong-Anh Khuong and Tönjes, Martje and Hovestadt, Volker and Albrecht, Steffen and Kool, Marcel and Nantel, Andre and Konermann, Carolin and Lindroth, Anders and Jäger, Natalie and Rausch, Tobias and Ryzhova, Marina and Korbel, Jan O and Hielscher, Thomas and Hauser, Peter and Garami, Miklos and Klekner, Almos and Bognar, Laszlo and Ebinger, Martin and Schuhmann, Martin U and Scheurlen, Wolfram and Pekrun, Arnulf and Frühwald, Michael C and Roggendorf, Wolfgang and Kramm, Christoph and Dürken, Matthias and Atkinson, Jeffrey and Lepage, Pierre and Montpetit, Alexandre and Zakrzewska, Magdalena and Zakrzewski, Krzystof and Liberski, Pawel P and Dong, Zhifeng and Siegel, Peter and Kulozik, Andreas E and Zapatka, Marc and Guha, Abhijit and Malkin, David and Felsberg, Jörg and Reifenberger, Guido and Von Deimling, Andreas and Ichimura, Koichi and Collins, V. Peter and Witt, Hendrik and Milde, Till and Witt, Olaf and Zhang, Cindy and Castelo-Branco, Pedro and Lichter, Peter and Faury, Damien and Tabori, Uri and Plass, Christoph and Majewski, Jacek and Pfister, Stefan M and Jabado, Nada
Nature (London), ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 226 - 231
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chromatin - metabolism | Humans | Molecular Sequence Data | Chromatin Assembly and Disassembly - genetics | Gene Expression Profiling | X-linked Nuclear Protein | Mutation - genetics | Tumor Suppressor Protein p53 - genetics | Exome - genetics | Histones - genetics | Glioblastoma - genetics | DNA Mutational Analysis | Base Sequence | Adaptor Proteins, Signal Transducing - genetics | Histones - metabolism | Nuclear Proteins - genetics | Child | Chromatin - genetics | DNA Helicases - genetics | Telomere - genetics | Pathogenesis | Mortality | Brain cancer | Epigenetics | DNA methylation | Genomes | Mutation | Telomerase | Index Medicus
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2. Full Text GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak
by Weber, Yvonne G and Storch, Alexander and Wuttke, Thomas V and Brockmann, Knut and Kempfle, Judith and Maljevic, Snezana and Margari, Lucia and Kamm, Christoph and Schneider, Susanne A and Huber, Stephan M and Pekrun, Arnulf and Roebling, Robert and Seebohm, Guiscard and Koka, Saisudha and Lang, Camelia and Kraft, Eduard and Blazevic, Dragica and Salvo-Vargas, Alberto and Fauler, Michael and Mottaghy, Felix M and Münchau, Alexander and Edwards, Mark J and Presicci, Anna and Margari, Francesco and Gasser, Thomas and Lang, Florian and Bhatia, Kailash P and Lehmann-Horn, Frank and Lerche, Holger
The Journal of clinical investigation, ISSN 0021-9738, 06/2008, Volume 118, Issue 6, pp. 2157 - 2168
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Xenopus | Amino Acid Sequence | Humans | Molecular Sequence Data | Male | Anemia, Hemolytic - genetics | Chorea - pathology | Animals | Glucose Transporter Type 1 - genetics | Models, Biological | Erythrocytes - metabolism | Glucose Transporter Type 1 - physiology | Glucose - metabolism | Adult | Female | Cations | Chorea - genetics | Anemia, Hemolytic - etiology | Physical Exertion | Care and treatment | Hemolytic anemia | Gene mutations | Diagnosis | Research | Risk factors | Movement disorders | Index Medicus | Abridged Index Medicus
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3. Full Text Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
by Cin, Huriye and Meyer, Claus and Herr, Ricarda and Janzarik, Wibke G and Lambert, Sally and Jones, David T. W and Jacob, Karine and Benner, Axel and Witt, Hendrik and Remke, Marc and Bender, Sebastian and Falkenstein, Fabian and Van Anh, Ton Nu and Olbrich, Heike and von Deimling, Andreas and Pekrun, Arnulf and Kulozik, Andreas E and Gnekow, Astrid and Scheurlen, Wolfram and Witt, Olaf and Omran, Heymut and Jabado, Nada and Collins, V Peter and Brummer, Tilman and Marschalek, Rolf and Lichter, Peter and Korshunov, Andrey and Pfister, Stefan M
Acta neuropathologica, ISSN 0001-6322, 6/2011, Volume 121, Issue 6, pp. 763 - 774
Medicine & Public Health | Pathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Astrocytoma - genetics | NIH 3T3 Cells | Sequence Deletion | Follow-Up Studies | Oligonucleotide Array Sequence Analysis | Humans | Brain Neoplasms - genetics | Child, Preschool | Infant | Male | Gene Expression Profiling | Mutation - genetics | Phosphorylation - genetics | Animals | MAP Kinase Signaling System - genetics | Transfection - methods | Comparative Genomic Hybridization | Oncogene Proteins, Fusion - genetics | Proto-Oncogene Proteins B-raf - genetics | Statistics, Nonparametric | Female | Mice | Chromosomes, Human, Pair 7 - genetics | Gene Expression Regulation, Neoplastic - genetics | Care and treatment | Molecular genetics | Oncology, Experimental | Leukemia | Genetic research | Cytogenetics | Research | Universities and colleges | Histochemistry | Biometry | Cancer | Index Medicus | Drugs | Phosphorylation | MAP kinase | Raf protein | Chromosome deletion | Gene deletion | raf1 gene | Gene fusion | K-Ras protein | Signal transduction | DNA microarrays | chromosome 7 | gene duplication | genomics | Mutation | gene rearrangement | Astrocytoma | Tumors
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4. Full Text Prognostic impact of distinct genetic entities in pediatric diffuse glioma WHO‐grade II—Report from the German/Swiss SIOP‐LGG 2004 cohort
by Falkenstein, Fabian and Gessi, Marco and Kandels, Daniela and Ng, Ho‐Keung and Schmidt, René and Warmuth‐Metz, Monika and Bison, Brigitte and Krauss, Juergen and Kortmann, Rolf‐Dieter and Timmermann, Beate and Thomale, Ulrich‐Wilhelm and Albert, Michael H and Pekrun, Arnulf and Maaß, Eberhard and Gnekow, Astrid K and Pietsch, Torsten
International journal of cancer, ISSN 0020-7136, 10/2020, Volume 147, Issue 8, pp. 2159 - 2175
diffuse glioma WHO‐grade II | genetics | astrocytoma | Histone3 gene mutation | child | Life Sciences & Biomedicine | Oncology | Science & Technology | Pediatrics | Brain tumors | Radiation therapy | Survival | Patients | Mutants | Chemotherapy | Glioma | Biopsy | Medical prognosis | Neurofibromatosis | Risk assessment | Mutation | Tumors | Index Medicus
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5. Full Text HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment
by Milde, Till and Lodrini, Marco and Savelyeva, Larissa and Korshunov, Andrey and Kool, Marcel and Brueckner, Lena M and Antunes, André S. L. M and Oehme, Ina and Pekrun, Arnulf and Pfister, Stefan M and Kulozik, Andreas E and Witt, Olaf and Deubzer, Hedwig E
Journal of neuro-oncology, ISSN 0167-594X, 12/2012, Volume 110, Issue 3, pp. 335 - 348
Panobinostat | Neurology | Medicine & Public Health | Medulloblastoma | MYC | Vorinostat | Group 3 | HC-toxin | Irradiation | Oncology | Group 3 | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Humans | Child, Preschool | Male | Gene Expression Profiling | Medulloblastoma - pathology | Biomarkers, Tumor - metabolism | Cerebellar Neoplasms - pathology | Tumor Cells, Cultured | Medulloblastoma - genetics | Disease Models, Animal | Cerebellar Neoplasms - drug therapy | In Situ Hybridization, Fluorescence | Cerebellar Neoplasms - genetics | Mice, SCID | Blotting, Western | Magnetic Resonance Imaging | Animals | Comparative Genomic Hybridization | Histone Deacetylase Inhibitors - pharmacology | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Medulloblastoma - drug therapy | Index Medicus | Drugs | Histone deacetylase | Prognosis | Wnt protein | Brain tumors | Glial fibrillary acidic protein | Cytology | Data processing | Transplantation | Isochromosomes | Myc protein | Gene expression | p53 protein | Metastases | Cell death | Hedgehog protein | Children
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6. Full Text Disseminated oligodendroglial cell-like leptomeningeal tumors: preliminary diagnostic and therapeutic results for a novel tumor entity
by Preuss, Matthias and Christiansen, Holger and Merkenschlager, Andreas and Hirsch, Franz Wolfgang and Kiess, Wieland and Müller, Wolf and Kästner, Stefanie and Henssler, Andreas and Pekrun, Arnulf and Hauch, Holger and Nathrath, Michaela and Meixensberger, Jürgen and Pietsch, Torsten and Kuchelmeister, Klaus
Journal of neuro-oncology, ISSN 0167-594X, 8/2015, Volume 124, Issue 1, pp. 65 - 74
Neurology | Leptomeningeal gliomatosis | Medicine & Public Health | Diffuse leptomeningeal neuroepithelial tumor | Disseminated oligodendroglial-like leptomeningeal tumor | Hydrocephalus | Oncology | Diffuse leptomeningeal glioneuronal tumor | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Health aspects | Algorithms
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7. Full Text Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS)
by Scheer, Monika and Blank, Bernd and Bauer, Sebastian and Vokuhl, Christian and Stegmaier, Sabine and Feuchtgruber, Simone and Henssen, Anton and Sparber-Sauer, Monika and Eggert, Angelika and Handgretinger, Ruppert and Pekrun, Arnulf and Rossig, Claudia and Rutkowski, Stefan and Schlegel, Paul-Gerhardt and Schrappe, Martin and Simon, Thorsten and Kazanowska, Bernarda and Niggli, Felix and Ladenstein, Ruth and Ljungman, Gustaf and Jahnukainen, Kirsi and Fuchs, Joerg and Bielack, Stefan S and Koscielniak, Ewa and Klingebiel, Thomas and CWS and Cooperative Weichteilsarkom Studiengruppe [CWS] and The Cooperative Weichteilsarkom Studiengruppe [CWS]
Journal of cancer research and clinical oncology, ISSN 0171-5216, 04/2020, Volume 146, Issue 4, pp. 953 - 960
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasm Invasiveness | Humans | Child, Preschool | Infant | Male | Sarcoma, Synovial - surgery | Young Adult | Neoplasm Metastasis | Adolescent | Age of Onset | Female | Neoplasm Staging | Sarcoma, Synovial - pathology | Child | Index Medicus
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8. Full Text Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma
by Desch, Ann-Kathrin and Hartung, Kristin and Botzen, Ante and Brobeil, Alexander and Rummel, Mathias and Kurch, Lars and Georgi, Thomas and Jox, Theresa and Bielack, Stefan and Burdach, Stefan and Classen, Carl Friedrich and Claviez, Alexander and Debatin, Klaus-Michael and Ebinger, Martin and Eggert, Angelika and Faber, Joerg and Flotho, Christian and Fruehwald, Michael and Graf, Norbert and Jorch, Norbert and Kontny, Udo and Kramm, Christof and Kulozik, Andreas and Kuehr, Joachim and Sykora, Karl-Walter and Metzler, Markus and Mueller, Hermann L and Nathrath, Michaela and Nuesslein, Thomas and Paulussen, Michael and Pekrun, Arnulf and Reinhardt, Dirk and Reinhard, Harald and Roessig, Claudia and Sauerbrey, Axel and Schlegel, Paul-Gerhardt and Schneider, Dominik T and Scheurlen, Wolfram and Schweigerer, Lothar and Simon, Thorsten and Suttorp, Meinolf and Vorwerk, Peter and Schmitz, Roland and Kluge, Regine and Mauz-Koerholz, Christine and Koerholz, Dieter and Gattenloehner, Stefan and Braeuninger, Andreas
Leukemia, ISSN 0887-6924, 01/2020, Volume 34, Issue 1, pp. 151 - 166
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Antigens | Pediatrics | Medical colleges | Medical research | B cells | Non-Hodgkin's lymphomas | Vincristine | Cable television broadcasting industry | Analysis | DNA | Medicine, Experimental | Genetic aspects | Cancer | Genotyping | Nucleotides | Lymphoma | Deoxyribonucleic acid--DNA | Hodgkin's disease | Tumors | Gene sequencing | Index Medicus
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9. Full Text Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis
by Suwala, Abigail K and Stichel, Damian and Schrimpf, Daniel and Kloor, Matthias and Wefers, Annika K and Reinhardt, Annekathrin and Maas, Sybren L. N and Kratz, Christian P and Schweizer, Leonille and Hasselblatt, Martin and Snuderl, Matija and Abedalthagafi, Malak Sameer J and Abdullaev, Zied and Monoranu, Camelia M and Bergmann, Markus and Pekrun, Arnulf and Freyschlag, Christian and Aronica, Eleonora and Kramm, Christof M and Hinz, Felix and Sievers, Philipp and Korshunov, Aney and Kool, Marcel and Pfister, Stefan M and Sturm, Dominik and Jones, David T. W and Wick, Wolfgang and Unterberg, Aneas and Hartmann, Christian and Dodgshun, Anew and Tabori, Uri and Wesseling, Pieter and Sahm, Felix and von Deimling, Aneas and Reuss, David E
Acta neuropathologica, ISSN 0001-6322, 2020, Volume 141, Issue 1, pp. 85 - 100
Pathology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Prognosis | Yeast | Copy number | p53 Protein | AKT protein | Microsatellite instability | DNA repair | MSH6 protein | Colon cancer | Mismatch repair | DNA methylation | Deoxyribonucleic acid--DNA | Astrocytoma | Genotypes | Young adults | MLH1 protein | MSH2 protein | 1-Phosphatidylinositol 3-kinase | Mutants | Chemotherapy | Medical prognosis | Epigenetics | DNA sequencing | Tumors | Index Medicus
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