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Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 499 - 499
Copper-64-Diacetyl-bis(N-4-methylthiosemicarbazone) [Cu-64][Cu(ATSM)] is a hypoxia-targeting PET tracer with applications in oncology and cardiology. Upon... 
OXYGEN | MECHANISM | MULTIDISCIPLINARY SCIENCES | CARDIAC HYPOXIA | IN-VIVO | INTRACELLULAR PH | ISCHEMIA | CU-64-ATSM | FAILURE | PET
Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7527, pp. 431 - 435
Journal Article
Life Sciences, ISSN 0024-3205, 10/2012, Volume 91, Issue 13-14, pp. 544 - 549
Aims: To determine the pharmacology of ET - and ET -mediated β-arrestin recruitment and compare this to established human pharmacology of these receptors to... 
β-arrestin recruitment | Human left ventricle | Endothelin | BQ123 | Biased antagonist | Vasoconstriction | Biased agonist | Sitaxentan | Human pharmacology | Ambrisentan | BQ788
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 216 - 11
By the time cardiotoxicity-associated cardiac dysfunction is detectable by echocardiography it is often beyond meaningful intervention. 99mTc-sestamibi is used... 
Medical imaging | Echocardiography | Retention | Doxorubicin | Single photon emission computed tomography | Lipophilic | Mitochondria | Anthracycline | Computed tomography | Perfusion | Myocardium | Hypoxia | Membrane potential | Pharmacokinetics
Journal Article
Scientific reports, 01/2019, Volume 9, Issue 1, p. 216
By the time cardiotoxicity-associated cardiac dysfunction is detectable by echocardiography it is often beyond meaningful intervention. Tc-sestamibi is used... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 35, pp. 14486 - 14495
Nitrate (NO3-) and nitrite (NO2-) are known to be cardioprotective and to alter energy metabolism in vivo. NO3- action results from its conversion to NO2- by... 
OXIDATIVE STRESS | OXIDE | NITRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | INJURY | CYSTEINE | SWITCH | MASS-SPECTROMETRY | NITROSYLATION | PROTEOMICS | Index Medicus | S-nitrosation | redox regulation | nitrite | Bioenergetics | proteomics | mitochondria | OxICAT | heart | ischemia | redox
Journal Article
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 10/2018, Volume 123, pp. 88 - 91
Ischemia-reperfusion (IR) injury occurs when blood supply to an organ is disrupted and then restored, and underlies many disorders, notably myocardial... 
Ischemia-reperfusion injury | Mitochondria | Ischemic preconditioning | Succinate | CARDIAC & CARDIOVASCULAR SYSTEMS | INHIBITION | METABOLISM | ROS | STRESS | CELL BIOLOGY | Cell death | Oxidation-reduction reaction | Reperfusion injury | ischemia-reperfusion injury | succinate | ischemic preconditioning | mitochondria
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 09/2017, Volume 292, Issue 35, p. 14486
Journal Article
Journal Article