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1. Full Text Dopamine Agonists Diminish Value Sensitivity of the Orbitofrontal Cortex: A Trigger for Pathological Gambling in Parkinson's Disease?
by Van Eimeren, Thilo and Ballanger, Bénédicte and Pellecchia, Giovanna and Miyasaki, Janis M and Lang, Anthony E and Strafella, Antonio P
Neuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 12/2009, Volume 34, Issue 13, pp. 2758 - 2766
Reinforcement | Impulse control disorder | Reward | Addiction | FMRI | Dopamine agonist | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Dopamine Agonists - pharmacology | Levodopa - pharmacology | Parkinson Disease - complications | Benzothiazoles - pharmacology | Gambling - psychology | Levodopa - therapeutic use | Frontal Lobe - physiopathology | Humans | Middle Aged | Dopamine Agonists - therapeutic use | Male | Parkinson Disease - drug therapy | Psychomotor Performance - drug effects | Parkinson Disease - physiopathology | Parkinson Disease - psychology | Psychomotor Performance - physiology | Pramipexole | Magnetic Resonance Imaging | Frontal Lobe - drug effects | Risk-Taking | Benzothiazoles - therapeutic use
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2. Full Text The Role of VPS35 in the Pathobiology of Parkinson's Disease
by Sassone, Jenny and Reale, Chiara and Dati, Giovanna and Regoni, Maria and Pellecchia, Maria Teresa and Garavaglia, Barbara
Cellular and molecular neurobiology, ISSN 0272-4340, 03/2021, Volume 41, Issue 2, pp. 199 - 227
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genes | Medical genetics | Membrane proteins | Dopamine | Parkinson's disease | Hydrolase | Neurodegenerative diseases | Homeostasis | Synuclein | Autophagy | Proteins | Mitochondria | Neurodegeneration | Parkin protein | Mutation | LRRK2 protein | Protein transport | Chromosome 16 | Movement disorders | Neurotransmission | Phagocytosis | Dopamine receptors | Endosomes | Index Medicus
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3. Full Text Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder
by Uddin, Mohammed and Tammimies, Kristiina and Pellecchia, Giovanna and Alipanahi, Babak and Hu, Pingzhao and Wang, Zhuozhi and Pinto, Dalila and Lau, Lynette and Nalpathamkalam, Thomas and Marshall, Christian R and Blencowe, Benjamin J and Frey, Brendan J and Merico, Daniele and Yuen, Ryan K. C and Scherer, Stephen W
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 7, pp. 742 - 747
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Humans | RNA, Messenger - genetics | Child, Preschool | Exons - genetics | Infant | Male | Gene Regulatory Networks | Reverse Transcriptase Polymerase Chain Reaction | Case-Control Studies | Mutation, Missense - genetics | Brain - metabolism | Phenotype | Child Development Disorders, Pervasive - genetics | Adolescent | Brain - pathology | Adult | Female | Real-Time Polymerase Chain Reaction | Genetic aspects | Gene mutations | Gene expression | Health aspects | Exon (Molecular genetics) | Pervasive developmental disorders | Autism | Medical research | Mutation | Genomics | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Morphometric Correlation of Impulsivity in Medial Prefrontal Cortex
by Cho, Sang Soo and Cho, Sang Soo and Pellecchia, Giovanna and Pellecchia, Giovanna and Aminian, Kelly and Aminian, Kelly and Ray, Nicola and Ray, Nicola and Segura, Barbara and Segura, Barbara and Obeso, Ignacio and Obeso, Ignacio and Strafella, Antonio P and Strafella, Antonio P
Brain topography, ISSN 0896-0267, 7/2013, Volume 26, Issue 3, pp. 479 - 487
Neurology | Medial prefrontal cortex | Neurosciences | Impulsivity | Voxel based morphometry | Biomedicine | Magnetic resonance imaging | Decision making | Ventral striatum | Psychiatry | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Decision Making | Humans | Male | Statistics as Topic | Prefrontal Cortex - pathology | Neuropsychological Tests | Young Adult | Attention - physiology | Impulsive Behavior - pathology | Magnetic Resonance Imaging | Psychiatric Status Rating Scales | Adolescent | Brain Mapping | Adult | Female | Parkinson's disease | Index Medicus | Addiction
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5. Full Text RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation
by Jones, Robert A and Robinson, Tyler J and Liu, Jeff C and Shrestha, Mariusz and Voisin, Veronique and Ju, Youngjun and Chung, Philip E.D and Pellecchia, Giovanna and Fell, Victoria L and Bae, Sooin and Muthuswamy, Lakshmi and Datti, Alessandro and Egan, Sean E and Jiang, Zhe and Leone, Gustavo and Bader, Gary D and Schimmer, Aaron and Zacksenhaus, Eldad
The Journal of clinical investigation, ISSN 0021-9738, 10/2016, Volume 126, Issue 10, pp. 3739 - 3757
Neoplasm Transplantation | Protein Biosynthesis | Humans | Retinoblastoma Binding Proteins - deficiency | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Tumor Suppressor Protein p53 - metabolism | Mice, Transgenic | Mitochondrial Proteins - genetics | Tumor Suppressor Protein p53 - genetics | Protein Interaction Maps | Animals | Gene Amplification | Triple Negative Breast Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Mitochondrial Proteins - metabolism | Triple Negative Breast Neoplasms - metabolism | Triple Negative Breast Neoplasms - pathology | Cell Line, Tumor | Ubiquitin-Protein Ligases - deficiency | Female | Retinoblastoma Binding Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Care and treatment | Analysis | Breast cancer | Genetic aspects | Genetic transcription | Tumor proteins | Genetic translation | Risk factors | Medical research | Cell growth | Rodents | Software | Mutation | Metabolism | Gene expression | Experiments | Cancer therapies | Tumors | Apoptosis | Index Medicus | Abridged Index Medicus
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6. Full Text Alteration of endosomal trafficking is associated with early-onset parkinsonism caused by SYNJ1 mutations
by Fasano, D and Parisi, S and Pierantoni, Giovanna and Rosa, Anna and Picillo, Marina and Amodio, G and Pellecchia, Maria Teresa and Barone, P and Moltedo, O and Bonifati, Vincenzo and Michele, Giuseppe and Nitsch, L and Remondelli, P and Criscuolo, Chiara and Paladino, S
Cell death & disease, ISSN 2041-4889, 01/2018, Volume 9, Issue 3, pp. 385 - 15
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Basal ganglia | Transferrin | Epidermal growth factor | Fibroblasts | Central nervous system diseases | Homeostasis | Membrane trafficking | Mutation | Age | Movement disorders | Endosomes | Index Medicus
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7. Full Text PERK-mediated unfolded protein response activation and oxidative stress in PARK20 fibroblasts
by Amodio, G and Moltedo, O and Fasano, D and Zerillo, L and Oliveti, M and Di Pietro, P and Faraonio, R and Barone, Paolo and Pellecchia, Maria Teresa and Rosa, Anna and Michele, Giuseppe and Polishchuk, E and Polishchuk, R and Bonifati, Vincenzo and Nitsch, L and Pierantoni, Giovanna and Renna, M and Criscuolo, Chiara and Paladino, S and Remondelli, P
Frontiers in neuroscience, ISSN 1662-4548, 06/2019, Volume 13, pp. 673 - 673
Mitochondrial dysfunction | PARK20 | PERK (PKR-like endoplasmic reticulum kinase) | ER stress | Synaptojanin 1 | Membrane trafficking | Oxydative stress | Parkinson’s disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Proteins | Phosphatases | Oxidative stress | Basal ganglia | Immunoglobulins | Laboratories | Cytology | Homeostasis | Central nervous system diseases | Bipolar disorder | Dentistry | Phosphatase | Golgi apparatus | Medicine | Phosphatidylinositol | Signal transduction | Mitochondria | Protein folding | Fibroblasts | Mutation | Endoplasmic reticulum | Movement disorders | Neuroscience | oxydative stress | mitochondrial dysfunction | membrane trafficking
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8. Full Text Motor, cognitive and behavioral differences in MDS PSP phenotypes
by Picillo, Marina and Cuoco, Sofia and Tepedino, Maria Francesca and Cappiello, Arianna and Volpe, Giampiero and Erro, Roberto and Santangelo, Gabriella and Pellecchia, Maria Teresa and Barone, Paolo and PSP Salerno Study Grp and PSP Salerno study group and The PSP Salerno study group
Journal of neurology, ISSN 0340-5354, 7/2019, Volume 266, Issue 7, pp. 1727 - 1735
Neurology | Neurosciences | Medicine & Public Health | Progressive supranuclear palsy | Diagnostic criteria | MDS | Subtype | Neuroradiology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Diagnosis, Differential | Humans | Middle Aged | Movement Disorders - diagnosis | Movement Disorders - psychology | Male | Supranuclear Palsy, Progressive - psychology | Mental Disorders - psychology | Phenotype | Aged, 80 and over | Cognitive Dysfunction - psychology | Female | Aged | Cognitive Dysfunction - diagnosis | Retrospective Studies | Mental Disorders - diagnosis | Supranuclear Palsy, Progressive - diagnosis | Cohort Studies | Medicine, Experimental | Medical research | Research | Diagnosis | Basal ganglia | Phenotypes | Cognitive ability | Central nervous system diseases | Genotype & phenotype | Cognition & reasoning | Semantics | Dementia disorders | Apraxia | Paralysis | Movement disorders | Dementia | Index Medicus
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9. Full Text Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer
by Liu, Jeff C and Granieri, Letizia and Shrestha, Mariusz and Wang, Dong-Yu and Vorobieva, Ioulia and Rubie, Elizabeth A and Jones, Rob and Ju, YoungJun and Pellecchia, Giovanna and Jiang, Zhe and Palmerini, Carlo A and Ben-David, Yaacov and Egan, Sean E and Woodgett, James R and Bader, Gary D and Datti, Alessandro and Zacksenhaus, Eldad
Cell reports (Cambridge), ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 112 - 126
basal-like breast cancer | RB1 | WEE1 | CHK1 | CDC25 | therapy | PTEN |