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Frontiers in Molecular Neuroscience, ISSN 1662-5099, 09/2018, Volume 11, p. 313
Actin-based remodeling underlines spine morphogenesis and plasticity and is crucially involved in the processes that constantly reshape the circuitry of the... 
EPS8 | Synapse | Actin cytoskeleton | NMDA receptor | GluN2A | GluN2B | TONIC ACTIVATION | synapse | SUBUNIT COMPOSITION | SYNAPTIC PLASTICITY | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | actin cytoskeleton | DENDRITIC SPINES | AMPA RECEPTORS | AMBIENT GLUTAMATE | EXCITATORY SYNAPSES | BINDING PROTEINS | HUNTINGTONS-DISEASE | Morphogenesis | Schizophrenia | Methyl aspartate | Research | Actin
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2523 - 2538
A disintegrin and metalloproteinase 10 (ADAM10), a disintegrin and metalloproteinase that resides in the postsynaptic densities (PSDs) of excitatory synapses,... 
ALPHA-SECRETASE | DENDRITIC SPINES | MEDICINE, RESEARCH & EXPERIMENTAL | GLUTAMATE RECEPTORS | IDENTIFIES VARIANTS | AMPA RECEPTORS | LONG-TERM DEPRESSION | A-BETA | CELL-SURFACE | AMYLOID PRECURSOR PROTEIN | GENOME-WIDE ASSOCIATION | Amyloid Precursor Protein Secretases - genetics | Humans | Cercopithecus aethiops | Molecular Sequence Data | Fatty Acid-Binding Proteins - metabolism | Alzheimer Disease - pathology | Endocytosis | Amyloid beta-Protein Precursor - metabolism | Hippocampus - enzymology | Membrane Proteins - metabolism | Protein Interaction Domains and Motifs | Amino Acid Sequence | ADAM Proteins - chemistry | Membrane Proteins - genetics | ADAM10 Protein | Models, Molecular | Synapses - enzymology | Alzheimer Disease - enzymology | Amyloid Precursor Protein Secretases - chemistry | Long-Term Synaptic Depression | Amino Acid Motifs | Protein Interaction Mapping | Protein Transport | Cell Membrane - enzymology | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Membrane Proteins - chemistry | Neuronal Plasticity | Long-Term Potentiation | Protein Binding | Fatty Acid-Binding Proteins - chemistry | Mice | ADAM Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | COS Cells | Neuroplasticity | Physiological aspects | Development and progression | Genetic aspects | Research | Metalloenzymes | Alzheimer's disease | Proteins | Software | Alzheimers disease | Experiments | Cell Membrane | Fatty Acid-Binding Proteins | Life Sciences | Neuroscience | Amyloid Precursor Protein Secretases | Cognitive science | Biochemistry, Molecular Biology | ADAM Proteins | Alzheimer Disease | Membrane Proteins | Adaptor Proteins, Signal Transducing | Hippocampus | Synapses | Amyloid beta-Protein Precursor
Journal Article
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 10/2019, Volume 56, Issue 10, p. 7136
A disintegrin and metalloproteinase 10 (ADAM10) is a synaptic enzyme that has been previously shown to limit amyloid-[beta].sub.1--42 (A[beta].sub.1--42)... 
Oligomers | Enzymes | Peptides | Physiological aspects | Alzheimer's disease
Journal Article
European Journal of Haematology, ISSN 0902-4441, 06/2018, Volume 100, Issue 6, pp. 636 - 643
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 02/2018, Volume 233, Issue 2, pp. 1455 - 1467
During embryonic development, new arteries, and veins form from preexisting vessels in response to specific angiogenic signals. Angiogenic signaling is complex... 
Delta/Notch signaling | blood vessel formation growth | Vegf signaling | angiogenesis | transmembrane protein 230 | PHYSIOLOGY | EPHRIN-B2 | NOTCH | CELL BIOLOGY | DLL4 | ARTERIES | Delta | Notch signaling | SPADETAIL | IN-VIVO | NETWORK FORMATION | EMBRYONIC VASCULAR DEVELOPMENT | KNOCKDOWN | EXPRESSION | Amino Acid Sequence | Cell Proliferation | Signal Transduction | Animals, Genetically Modified | Endothelial Cells - metabolism | Membrane Proteins - genetics | Receptors, Notch - metabolism | Zebrafish Proteins - metabolism | Receptors, Notch - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Zebrafish - embryology | Zebrafish - genetics | Animals | Gene Expression Regulation, Developmental | Base Sequence | Zebrafish - metabolism | Conserved Sequence | Membrane Proteins - metabolism | Zebrafish Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Neovascularization, Physiologic | Embryonic development | Drug discovery | Endothelial growth factors | Endothelium | Cell proliferation | Network formation | Leukocyte migration | Blood vessels | Zebrafish | Gene expression | Arteries | Endothelial cells | Regeneration (physiology) | Embryonic growth stage | Angiogenesis | Regeneration | Signal transduction | Signaling | Embryogenesis | Conserved sequence | Cell number | Notch protein | Aberration | Vascular endothelial growth factor | Cell migration
Journal Article
Movement Disorders, ISSN 0885-3185, 07/2017, Volume 32, Issue 7, pp. 1035 - 1046
ABSTRACT Background: Recent studies support the therapeutic utility of repetitive transcranial magnetic stimulation in Parkinson's disease (PD), whose... 
corticostriatal synaptic plasticity | Parkinson's disease | transcranial magnetic stimulation | long‐term potentiation | glia | long-term potentiation | DEPRESSION | RAT | INCREASES | RELEASE | PREFRONTAL CORTEX | CLINICAL NEUROLOGY | NEUROINFLAMMATION | DISEASE | NEURONS | STRIATAL PLASTICITY | Motor Activity - physiology | Corpus Striatum - physiopathology | Rats, Wistar | Genes, Immediate-Early - physiology | Rats | Behavior, Animal - physiology | Male | Parkinsonian Disorders - chemically induced | Transcranial Magnetic Stimulation - methods | Adrenergic Agents - pharmacology | Corpus Striatum - metabolism | Cerebral Cortex - metabolism | Cerebral Cortex - physiopathology | Astrocytes - physiology | Patch-Clamp Techniques | Animals | Microdialysis | Microglia - physiology | Neuronal Plasticity - physiology | Oxidopamine - pharmacology | Parkinsonian Disorders - therapy | Dopamine - metabolism | Theta Rhythm - physiology | Physiological aspects | Phenols | Development and progression | Analysis | Adaptations | Potentiation | Basal ganglia | Plasticity (glial) | Glial cells | Motor task performance | Neuromodulation | Neuronal-glial interactions | Cell activation | Rodents | Neostriatum | Long-term depression | Movement disorders | Dopamine | Neurodegenerative diseases | Astrocytes | Long-term potentiation | Cortex | Attention | 6-Hydroxydopamine | Central nervous system diseases | Inflammation | Spiny neurons | Plasticity (synaptic) | Magnetic fields
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 11/2017, Volume 61, Issue 1, pp. 113 - 123
ADAM10 is the α-secretase that cleaves amyloid-β protein precursor in the non-amyloidogenic pathway in Alzheimer’s disease (AD) and is known to be regulated by... 
Amyloidogenesis | Post-transcription | Regulators | Neurodegenerative diseases | Ribonucleic acids | Gene regulation | MiRNA | Amyloid | Alzheimer's disease | Biological activity | Secretase
Journal Article