Medical Journal of Wuhan University, ISSN 1671-8852, 03/2019, Volume 40, Issue 2, pp. 338 - 341
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0120704
Major depressive disorder (MDD) is accompanied by atypical brain structure. This study first presents the alterations in the cortical surface of patients with...
DIRECT-CURRENT STIMULATION | WHITE-MATTER INTEGRITY | CORTICAL THICKNESS | ABNORMALITIES | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL CONNECTIVITY | PSYCHOMOTOR RETARDATION | DEFAULT-MODE NETWORK | SUBCORTICAL VOLUME | COGNITIVE DEFICITS | WORKING-MEMORY | Depressive Disorder, Major - pathology | Magnetic Resonance Imaging | Humans | Middle Aged | Cerebral Cortex - pathology | Brain - pathology | Adult | Female | Male | Brain | Disease susceptibility | Major depressive disorder | Health care | Neuroimaging | Neurosciences | Cerebral cortex | Mental disorders | Neurobiology | Mental health | Mental depression | Alterations | Maps | Cortex (parietal) | Cortex (frontal) | Cortex (cingulate) | Medical imaging | Dopamine | Patients | Emotions | Medicine | Studies | Brain research | Hospitals | Researchers | Magnetic resonance imaging | Morphometry | Surface area
DIRECT-CURRENT STIMULATION | WHITE-MATTER INTEGRITY | CORTICAL THICKNESS | ABNORMALITIES | MULTIDISCIPLINARY SCIENCES | FUNCTIONAL CONNECTIVITY | PSYCHOMOTOR RETARDATION | DEFAULT-MODE NETWORK | SUBCORTICAL VOLUME | COGNITIVE DEFICITS | WORKING-MEMORY | Depressive Disorder, Major - pathology | Magnetic Resonance Imaging | Humans | Middle Aged | Cerebral Cortex - pathology | Brain - pathology | Adult | Female | Male | Brain | Disease susceptibility | Major depressive disorder | Health care | Neuroimaging | Neurosciences | Cerebral cortex | Mental disorders | Neurobiology | Mental health | Mental depression | Alterations | Maps | Cortex (parietal) | Cortex (frontal) | Cortex (cingulate) | Medical imaging | Dopamine | Patients | Emotions | Medicine | Studies | Brain research | Hospitals | Researchers | Magnetic resonance imaging | Morphometry | Surface area
Journal Article
Shanghai Archives of Psychiatry, ISSN 1002-0829, 08/2015, Volume 27, Issue 4, pp. 246 - 248
Obsessive-compulsive symptoms are common in patients with bipolar disorders. This comorbid condition complicates the clinical treatment of the two disorders,...
Comorbidity | Bipolar disorder | Obsessive-compulsive disorder | Medical research | Mania | Medicine, Experimental | Serotonin uptake inhibitors | Evidence-based medicine | bipolar disorder | comorbidity | obsessive-compulsive disorder | Forum
Comorbidity | Bipolar disorder | Obsessive-compulsive disorder | Medical research | Mania | Medicine, Experimental | Serotonin uptake inhibitors | Evidence-based medicine | bipolar disorder | comorbidity | obsessive-compulsive disorder | Forum
Journal Article
Journal of Psychiatric Research, ISSN 0022-3956, 2016, Volume 78, pp. 65 - 71
Abstract Recently, increasing evidence has indicated that dysfunction of microRNA-124 (miR-124) might be involved in the pathophysiology and treatment of major...
Psychiatry | miR-124 | MicroRNA | Treatment | Expression | PBMC | Major depressive disorder | MiR-124 | NERVOUS-SYSTEM | PSYCHIATRY | RATS | RECEPTOR | SCHIZOPHRENIA | ANTIDEPRESSANTS | MESSENGER-RNA | MOOD DISORDERS | GENE-EXPRESSION | PATHWAY ANALYSIS | BRAIN | Depressive Disorder, Major - blood | Leukocytes, Mononuclear - metabolism | Leukocytes, Mononuclear - drug effects | Follow-Up Studies | Area Under Curve | Humans | Male | MicroRNAs - metabolism | Treatment Outcome | Biomarkers - blood | Antidepressive Agents - therapeutic use | Adult | Female | ROC Curve | Real-Time Polymerase Chain Reaction | Depressive Disorder, Major - drug therapy | Medical colleges | Care and treatment | Antidepressants | Analysis | Genetic research | Psychiatric services
Psychiatry | miR-124 | MicroRNA | Treatment | Expression | PBMC | Major depressive disorder | MiR-124 | NERVOUS-SYSTEM | PSYCHIATRY | RATS | RECEPTOR | SCHIZOPHRENIA | ANTIDEPRESSANTS | MESSENGER-RNA | MOOD DISORDERS | GENE-EXPRESSION | PATHWAY ANALYSIS | BRAIN | Depressive Disorder, Major - blood | Leukocytes, Mononuclear - metabolism | Leukocytes, Mononuclear - drug effects | Follow-Up Studies | Area Under Curve | Humans | Male | MicroRNAs - metabolism | Treatment Outcome | Biomarkers - blood | Antidepressive Agents - therapeutic use | Adult | Female | ROC Curve | Real-Time Polymerase Chain Reaction | Depressive Disorder, Major - drug therapy | Medical colleges | Care and treatment | Antidepressants | Analysis | Genetic research | Psychiatric services
Journal Article
Shanghai Archives of Psychiatry, ISSN 1002-0829, 12/2014, Volume 26, Issue 6, pp. 365 - 367
There is on-going controversy about the definition and sub-classification of treatment-resistant depression (TRD) that makes it difficult to assess the...
Combined treatment | Adjunctive treatment | Classification | Treatment-resistant depression | Research | Drug therapy | Antidepressants | Health aspects | Depression, Mental | treatment-resistant depression | combined treatment | Antidepressant polypharmacy | classification | adjunctive treatment | Forum
Combined treatment | Adjunctive treatment | Classification | Treatment-resistant depression | Research | Drug therapy | Antidepressants | Health aspects | Depression, Mental | treatment-resistant depression | combined treatment | Antidepressant polypharmacy | classification | adjunctive treatment | Forum
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 7/2016, Volume 53, Issue 5, pp. 2936 - 2943
Genetic variation in the gene encoding zinc finger protein 804A gene (ZNF804A) has been identified to be associated with bipolar disorder in genome-wide...
Neurology | Neurosciences | Biomedicine | Neurobiology | ZNF804A | Bipolar disorder | Han Chinese | eQTL | Subtype | Cell Biology | HUMAN BRAIN | METAANALYSIS | SUSCEPTIBILITY | SCHIZOPHRENIA | IDENTIFICATION | VARIANT | NEUROSCIENCES | ALLELIC DIFFERENCES | ASSOCIATION | EXPRESSION | Gene Frequency - genetics | Genetic Predisposition to Disease | Humans | RNA, Messenger - genetics | Risk Factors | Male | RNA, Messenger - metabolism | Bipolar Disorder - genetics | Case-Control Studies | Kruppel-Like Transcription Factors - metabolism | Alleles | Brain - pathology | Polymorphism, Single Nucleotide - genetics | Adult | Female | Odds Ratio | Kruppel-Like Transcription Factors - genetics | RNA | Genomics | Genetic research | Genetic aspects | DNA binding proteins | Risk factors | Psychiatric services | Genetics
Neurology | Neurosciences | Biomedicine | Neurobiology | ZNF804A | Bipolar disorder | Han Chinese | eQTL | Subtype | Cell Biology | HUMAN BRAIN | METAANALYSIS | SUSCEPTIBILITY | SCHIZOPHRENIA | IDENTIFICATION | VARIANT | NEUROSCIENCES | ALLELIC DIFFERENCES | ASSOCIATION | EXPRESSION | Gene Frequency - genetics | Genetic Predisposition to Disease | Humans | RNA, Messenger - genetics | Risk Factors | Male | RNA, Messenger - metabolism | Bipolar Disorder - genetics | Case-Control Studies | Kruppel-Like Transcription Factors - metabolism | Alleles | Brain - pathology | Polymorphism, Single Nucleotide - genetics | Adult | Female | Odds Ratio | Kruppel-Like Transcription Factors - genetics | RNA | Genomics | Genetic research | Genetic aspects | DNA binding proteins | Risk factors | Psychiatric services | Genetics
Journal Article
Journal Article
卫生职业教育, ISSN 1671-1246, 2017, Issue 15, pp. 108 - 109
Journal Article
Psychopharmacology, ISSN 0033-3158, 2/2014, Volume 231, Issue 4, pp. 685 - 693
In clinical practice, ketamine, an antagonist of the N-methyl-d-aspartate receptor (NMDAR), is used to alleviate depressive symptoms in patients with major...
Neurosciences | Biomedicine | Genetic predictor | Treatment-resistant depression | Pharmacology/Toxicology | Psychiatry | GRIN2B | Major depressive disorder | ANTAGONIST | EFFICACY | PSYCHIATRY | BIPOLAR DISORDER | NEUROSCIENCES | NR2B | POLYMORPHISMS | GLUTAMATE | TREATMENT RESPONSE | PAROXETINE | PHARMACOLOGY & PHARMACY | NTRK2 GENE | ASSOCIATION | Haplotypes | Genetic Predisposition to Disease | Gene Frequency | Humans | Male | Genotyping Techniques | Depressive Disorder, Treatment-Resistant - genetics | Receptors, N-Methyl-D-Aspartate - genetics | Depressive Disorder, Major - genetics | Adult | Female | Polymorphism, Single Nucleotide | Longitudinal Studies | Methyl aspartate | Research | Analysis | Genetic polymorphisms | Mental depression | Neuropsychology | Antagonist drugs | Psychopharmacology
Neurosciences | Biomedicine | Genetic predictor | Treatment-resistant depression | Pharmacology/Toxicology | Psychiatry | GRIN2B | Major depressive disorder | ANTAGONIST | EFFICACY | PSYCHIATRY | BIPOLAR DISORDER | NEUROSCIENCES | NR2B | POLYMORPHISMS | GLUTAMATE | TREATMENT RESPONSE | PAROXETINE | PHARMACOLOGY & PHARMACY | NTRK2 GENE | ASSOCIATION | Haplotypes | Genetic Predisposition to Disease | Gene Frequency | Humans | Male | Genotyping Techniques | Depressive Disorder, Treatment-Resistant - genetics | Receptors, N-Methyl-D-Aspartate - genetics | Depressive Disorder, Major - genetics | Adult | Female | Polymorphism, Single Nucleotide | Longitudinal Studies | Methyl aspartate | Research | Analysis | Genetic polymorphisms | Mental depression | Neuropsychology | Antagonist drugs | Psychopharmacology
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0128947
Journal Article
Psychiatry Research, ISSN 0165-1781, 2016
Abstract Background Previousstudies have shown that the genes involved in synaptic density and plasticity were downregulated in bipolar disorder (BD)...
Psychiatry
Psychiatry
Journal Article
Comprehensive Psychiatry, ISSN 0010-440X, 11/2018, Volume 87, pp. 32 - 37
This study aimed to investigate the clinical characteristics of somatic symptoms of patients in China who suffer from major depressive disorder (MDD). 3273...
PSYCHOMETRIC PROPERTIES | POPULATION | GENDER-DIFFERENCE | PRIMARY-CARE | RECOGNITION | ANXIETY | PSYCHIATRY | PSYCHOLOGICAL SYMPTOMS | QUICK INVENTORY | PREVALENCE | SYMPTOMATOLOGY | Diagnostic and Statistical Manual of Mental Disorders | Prevalence | Pain - epidemiology | Somatoform Disorders - psychology | Sleep Initiation and Maintenance Disorders - diagnosis | Humans | Middle Aged | Male | China - epidemiology | Depressive Disorder, Major - epidemiology | Sleep Initiation and Maintenance Disorders - epidemiology | Depressive Disorder, Major - psychology | Young Adult | Pain - psychology | Somatoform Disorders - epidemiology | Adolescent | Somatoform Disorders - diagnosis | Adult | Female | Surveys and Questionnaires | Depressive Disorder, Major - diagnosis | Pain - diagnosis | Sleep Initiation and Maintenance Disorders - psychology | Medical research | Hospitals | Insomnia | Analysis | Medicine, Experimental | Mental illness | Psychiatric services | Major depressive disorder | Mental disorders | Comorbidity | Headaches | Nervous system | Research | Mental depression | Muscular system | Respiratory system | Mental health care | Pain | Anxieties | Age
PSYCHOMETRIC PROPERTIES | POPULATION | GENDER-DIFFERENCE | PRIMARY-CARE | RECOGNITION | ANXIETY | PSYCHIATRY | PSYCHOLOGICAL SYMPTOMS | QUICK INVENTORY | PREVALENCE | SYMPTOMATOLOGY | Diagnostic and Statistical Manual of Mental Disorders | Prevalence | Pain - epidemiology | Somatoform Disorders - psychology | Sleep Initiation and Maintenance Disorders - diagnosis | Humans | Middle Aged | Male | China - epidemiology | Depressive Disorder, Major - epidemiology | Sleep Initiation and Maintenance Disorders - epidemiology | Depressive Disorder, Major - psychology | Young Adult | Pain - psychology | Somatoform Disorders - epidemiology | Adolescent | Somatoform Disorders - diagnosis | Adult | Female | Surveys and Questionnaires | Depressive Disorder, Major - diagnosis | Pain - diagnosis | Sleep Initiation and Maintenance Disorders - psychology | Medical research | Hospitals | Insomnia | Analysis | Medicine, Experimental | Mental illness | Psychiatric services | Major depressive disorder | Mental disorders | Comorbidity | Headaches | Nervous system | Research | Mental depression | Muscular system | Respiratory system | Mental health care | Pain | Anxieties | Age
Journal Article
Journal of Affective Disorders, ISSN 0165-0327, 08/2018, Volume 235, pp. 135 - 141
Suicide risk is greatly increased in depression. Detection of those at risk is clinically important. Hence, this study aimed to evaluate the prevalence and...
Depression | Chinese | Suicidal ideation | Risk factors | Symptoms | Prevalence | Area Under Curve | Humans | Middle Aged | Risk Factors | Suicide, Attempted - statistics & numerical data | Logistic Models | Male | Suicidal Ideation | China - epidemiology | Depressive Disorder, Major - epidemiology | Depressive Disorder, Major - psychology | Suicide, Attempted - psychology | Asian Continental Ancestry Group - psychology | Adult | Female | ROC Curve | Odds Ratio | Asian Continental Ancestry Group - statistics & numerical data | Medicine, Experimental | Medical research | Suicidal behavior | Depression, Mental
Depression | Chinese | Suicidal ideation | Risk factors | Symptoms | Prevalence | Area Under Curve | Humans | Middle Aged | Risk Factors | Suicide, Attempted - statistics & numerical data | Logistic Models | Male | Suicidal Ideation | China - epidemiology | Depressive Disorder, Major - epidemiology | Depressive Disorder, Major - psychology | Suicide, Attempted - psychology | Asian Continental Ancestry Group - psychology | Adult | Female | ROC Curve | Odds Ratio | Asian Continental Ancestry Group - statistics & numerical data | Medicine, Experimental | Medical research | Suicidal behavior | Depression, Mental
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 9/2017, Volume 54, Issue 7, pp. 5573 - 5582
There is a high rate of misdiagnosis between major depressive disorder (MDD) and bipolar disorder (BD) in clinical practice. Our previous work provided...
Neurology | Neurosciences | Biomedicine | Brain-derived neurotrophic factor | Neurobiology | Bipolar disorder | Precursor | Major depressive disorder | Cell Biology | TREATMENT-RESISTANT DEPRESSION | METAANALYSIS | NEUROTROPHIC FACTOR BDNF | NEUROSCIENCES | MATRIX METALLOPROTEINASES | PLASMA-LEVELS | MATURE BDNF | SERUM-LEVELS | PSYCHIATRIC-DISORDERS | EXPRESSION | PRECURSOR PROBDNF | Antidepressive Agents - therapeutic use | Enzyme-Linked Immunosorbent Assay - methods | Diagnosis, Differential | Humans | Middle Aged | Adult | Female | Male | Brain-Derived Neurotrophic Factor - blood | Depressive Disorder, Major - diagnosis | Bipolar Disorder - diagnosis | Enzymes | Yuan (China) | Medical colleges | Antidepressants | Analysis | Diagnosis | Psychiatric services | Brain | Mental depression | Assaying | Medical diagnosis | Patients | Differential diagnosis | Diagnostic systems | Kits | Enzyme-linked immunosorbent assay | Plasmas (physics)
Neurology | Neurosciences | Biomedicine | Brain-derived neurotrophic factor | Neurobiology | Bipolar disorder | Precursor | Major depressive disorder | Cell Biology | TREATMENT-RESISTANT DEPRESSION | METAANALYSIS | NEUROTROPHIC FACTOR BDNF | NEUROSCIENCES | MATRIX METALLOPROTEINASES | PLASMA-LEVELS | MATURE BDNF | SERUM-LEVELS | PSYCHIATRIC-DISORDERS | EXPRESSION | PRECURSOR PROBDNF | Antidepressive Agents - therapeutic use | Enzyme-Linked Immunosorbent Assay - methods | Diagnosis, Differential | Humans | Middle Aged | Adult | Female | Male | Brain-Derived Neurotrophic Factor - blood | Depressive Disorder, Major - diagnosis | Bipolar Disorder - diagnosis | Enzymes | Yuan (China) | Medical colleges | Antidepressants | Analysis | Diagnosis | Psychiatric services | Brain | Mental depression | Assaying | Medical diagnosis | Patients | Differential diagnosis | Diagnostic systems | Kits | Enzyme-linked immunosorbent assay | Plasmas (physics)
Journal Article
Brain Imaging and Behavior, ISSN 1931-7557, 10/2019, Volume 13, Issue 5, pp. 1255 - 1264
Reported structural abnormalities of patients with bipolar disorder (BD) are inconsistent and the use of psychotropic medication is one of the sources of...
Neurosciences | Biomedicine | MRI | Mood stabilizers | Bipolar disorder | Neuropsychology | Prefrontal cortex | Psychiatry | Neuroradiology | Euthymia | SURFACE-BASED ANALYSIS | GRAY-MATTER VOLUME | HIPPOCAMPAL VOLUMES | ABNORMALITIES | VALPROIC ACID | AMYGDALA VOLUME | NEUROIMAGING | CEREBRAL-CORTEX | LITHIUM TREATMENT | INCREASE | DISORDER | Neuroimaging | Drugs | Brain | Cortex (prefrontal) | Medical imaging | Brain architecture | Abnormalities | Lithium | Valproic acid | Drug development | Anatomy | Patients | Image acquisition | Psychotropic drugs | Heterogeneity | Neurology | Mood | Magnetic resonance imaging | Cortex (frontal) | Biomarkers
Neurosciences | Biomedicine | MRI | Mood stabilizers | Bipolar disorder | Neuropsychology | Prefrontal cortex | Psychiatry | Neuroradiology | Euthymia | SURFACE-BASED ANALYSIS | GRAY-MATTER VOLUME | HIPPOCAMPAL VOLUMES | ABNORMALITIES | VALPROIC ACID | AMYGDALA VOLUME | NEUROIMAGING | CEREBRAL-CORTEX | LITHIUM TREATMENT | INCREASE | DISORDER | Neuroimaging | Drugs | Brain | Cortex (prefrontal) | Medical imaging | Brain architecture | Abnormalities | Lithium | Valproic acid | Drug development | Anatomy | Patients | Image acquisition | Psychotropic drugs | Heterogeneity | Neurology | Mood | Magnetic resonance imaging | Cortex (frontal) | Biomarkers
Journal Article
Shanghai Archives of Psychiatry, ISSN 1002-0829, 06/2016, Volume 28, Issue 3, pp. 166 - 168
Bipolar Disorder (BD) features with various of clinical symptoms, leading to the misdiagnosis of major depressive disorder (MDD). The atypical features (ATFs)...
Bipolar disorder | Major depressive disorder, atypical features, mood reactivity | Mood (Psychology) | Research | Analysis
Bipolar disorder | Major depressive disorder, atypical features, mood reactivity | Mood (Psychology) | Research | Analysis
Journal Article
FRONTIERS IN PSYCHIATRY, ISSN 1664-0640, 11/2018, Volume 9, p. 552
Background: Metabolic factors in the kynurenine pathway (KP) have been widely accepted as being a major mechanism in Major Depressive Disorder (MDD). However,...
TRYPTOPHAN | kynurenine pathway | major depressive disorder | PSYCHIATRY | INFLAMMATION | HIPPOCAMPAL | quinolinic acid | mass spectrometry | BIPOLAR DISORDER | kynurenic acid | BRAIN | Development and progression | Research | Diagnosis | Metabolism | Major depressive disorder
TRYPTOPHAN | kynurenine pathway | major depressive disorder | PSYCHIATRY | INFLAMMATION | HIPPOCAMPAL | quinolinic acid | mass spectrometry | BIPOLAR DISORDER | kynurenic acid | BRAIN | Development and progression | Research | Diagnosis | Metabolism | Major depressive disorder
Journal Article